KEGG   Dipodomys ordii (Ord's kangaroo rat): 105992227
Entry
105992227         CDS       T07834                                 
Symbol
Mgst1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
dord  Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00480  Glutathione metabolism
dord00980  Metabolism of xenobiotics by cytochrome P450
dord00982  Drug metabolism - cytochrome P450
dord00983  Drug metabolism - other enzymes
dord01100  Metabolic pathways
dord01524  Platinum drug resistance
dord05200  Pathways in cancer
dord05204  Chemical carcinogenesis - DNA adducts
dord05207  Chemical carcinogenesis - receptor activation
dord05208  Chemical carcinogenesis - reactive oxygen species
dord05225  Hepatocellular carcinoma
dord05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dord00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    105992227 (Mgst1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    105992227 (Mgst1)
   00982 Drug metabolism - cytochrome P450
    105992227 (Mgst1)
   00983 Drug metabolism - other enzymes
    105992227 (Mgst1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105992227 (Mgst1)
   05204 Chemical carcinogenesis - DNA adducts
    105992227 (Mgst1)
   05207 Chemical carcinogenesis - receptor activation
    105992227 (Mgst1)
   05208 Chemical carcinogenesis - reactive oxygen species
    105992227 (Mgst1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    105992227 (Mgst1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    105992227 (Mgst1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    105992227 (Mgst1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:dord02000]
    105992227 (Mgst1)
Enzymes [BR:dord01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     105992227 (Mgst1)
Transporters [BR:dord02000]
 Other transporters
  Pores ion channels [TC:1]
   105992227 (Mgst1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 105992227
NCBI-ProteinID: XP_012880504
UniProt: A0A1S3FWV5
LinkDB
Position
Unknown
AA seq 178 aa
MEKEAGFQKEPGGHGWLLAWPPDRFGDDSVVFWNVPEGGGGRDQCILEYIICRIPLLPPS
GIRGQVFANPEDCASFGKGENTKKYLRTDDSVERVRRAHLNDLENVVPFVGVGLLYALSR
PAPATALLHFRVFAGARLFHTVAYLLPLPQPSRALGFFVGYGVTLSMAGRVLQAALRL
NT seq 537 nt   +upstreamnt  +downstreamnt
atggagaaggaggctgggttccagaaggagccaggaggccatggctggctgttggcctgg
ccccctgatcggtttggggatgactccgtggtgttctggaacgttcctgagggtgggggt
gggcgggatcagtgcatcctggagtatataatttgtcgtattcctctcctccccccctct
ggtattcggggtcaggtgtttgccaacccagaagactgtgcgagtttcggcaagggagag
aacaccaagaagtatcttcggacggacgacagcgtggagcgtgtgcggagggcgcacctg
aacgacctggagaacgtggttcccttcgtgggcgtcgggttgctgtacgcgctgagccgg
cccgcgccggccacggcgctgctgcacttccgcgtgttcgcgggcgcgcggctcttccac
accgtggcctacctgctgccgctgccgcagccaagccgcgcgctcggcttcttcgtgggc
tacggggtgacgctgtccatggccggccgcgtgctgcaggcggcgctgcgcctctga

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