Dipodomys ordii (Ord's kangaroo rat): 105999053
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Entry
105999053 CDS
T07834
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord04217
Necroptosis
dord04380
Osteoclast differentiation
dord04620
Toll-like receptor signaling pathway
dord04621
NOD-like receptor signaling pathway
dord04630
JAK-STAT signaling pathway
dord04658
Th1 and Th2 cell differentiation
dord04659
Th17 cell differentiation
dord05145
Toxoplasmosis
dord05160
Hepatitis C
dord05161
Hepatitis B
dord05162
Measles
dord05164
Influenza A
dord05165
Human papillomavirus infection
dord05167
Kaposi sarcoma-associated herpesvirus infection
dord05168
Herpes simplex virus 1 infection
dord05169
Epstein-Barr virus infection
dord05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105999053 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
105999053 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105999053 (Tyk2)
04621 NOD-like receptor signaling pathway
105999053 (Tyk2)
04658 Th1 and Th2 cell differentiation
105999053 (Tyk2)
04659 Th17 cell differentiation
105999053 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
105999053 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
105999053 (Tyk2)
05160 Hepatitis C
105999053 (Tyk2)
05171 Coronavirus disease - COVID-19
105999053 (Tyk2)
05164 Influenza A
105999053 (Tyk2)
05162 Measles
105999053 (Tyk2)
05168 Herpes simplex virus 1 infection
105999053 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
105999053 (Tyk2)
05169 Epstein-Barr virus infection
105999053 (Tyk2)
05165 Human papillomavirus infection
105999053 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105999053 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dord01001
]
105999053 (Tyk2)
Enzymes [BR:
dord01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105999053 (Tyk2)
Protein kinases [BR:
dord01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105999053 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
105999053
NCBI-ProteinID:
XP_012889393
Ensembl:
ENSDORG00000010102
UniProt:
A0A1S3GKJ0
LinkDB
All DBs
Position
Unknown
AA seq
1027 aa
AA seq
DB search
MSLQKRFPAQSSSTAVDAQPMAAVGSVKVLLHWVGPAGGEPWVTFSDSLLTAEEICVQIA
HKIGITPPCFNLFALFDAQAGVWLPPNHTLDMSRDTNMTLLFRMRFYFRNWHGLNSQEPA
VYRCGFPGVEAPSERAEQGVQLLDSASFEYLFEQVQVTGTGGIQWRPVQAEGLGSQDSKG
GNGGSRNPQARPSRKKGKAHPAGQQVVGRPWESPWTYFCDFQDISHVVLTDSRVSIRRQD
NQCLEFSLLSRASALSFVALVDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLDPF
VQAKLRPEDGLYLIHWSTNHLYRLILTVAQRDSAPGVRGLRLRKFPILQEAGAFVLEGWD
RSFASIRELRVALQGCALRAGEDCFPLRRCCLPRPGEISNLLIMRGSRPNSQPPNLSQLS
FHRVHQDEITQLSHLGQGTRTNVYEGLLRVGVPEEEEEDKVDSGISLEPCGGRGQELRVV
LKVLDPSHHDIALAFYETASLMSQVSHAHLAFVHGVCVRGSENIMVTEYVEHGPLDVWLR
RERGHVPMAWKVAVTQQLASALSYLEDKSLVHGNVCGRNILLARPGLAEDTSPFIKLSDP
GVGLGALSREERVERIPWTAPECLTGGANSLSTAADKWGFGATLLEICFDGEAPLQGRGP
SEKERFYQKQHQLPEPSCPELATLTSQCLTYEPAQRPSFRTILRDLTRLQPHNLVDISTV
NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQL
RSGWRREIDILRTLYHEHIVKYKGCCEDPGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQL
LLFAQQICKGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED
GDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTHCDSSQSPPSKFFELIGLTQGQMT
VLRLTELLERGERLPRPDKCPSEVYLLMKNCWELEASFRPTFQNLIPILKMAHDKYQAQA
PSVFSVC
NT seq
3084 nt
NT seq
+upstream
nt +downstream
nt
atgtcccttcagaagcgatttccagcccagtccagctccacagcggtggacgcccagccc
atggctgccgtgggaagtgtgaaggtgctgctgcactgggtcgggcccgcaggtggggag
ccctgggtcaccttcagcgattccctgctgactgcagaggagatctgtgttcagatcgca
cacaaaatcggcatcactccgccctgtttcaatctctttgccctcttcgatgcccaggcc
ggagtctggctgcccccaaaccacaccctggacatgtccagagacacaaatatgacgctg
ttattccgaatgaggttttatttccgcaactggcatggcctgaattctcaggagcctgct
gtataccgctgcggattcccaggggttgaagcaccctcagaacgggcagagcagggggtg
cagctcttggactcagcctcgtttgagtacctctttgagcaggtgcaggtgaccggcacg
gggggcatccagtggcggccggtgcaggccgaggggctgggttcccaggattccaagggc
ggcaatggcggcagcaggaacccccaggcccgcccgtcccggaagaaaggcaaggcccac
ccggcgggacagcaggtggtgggcaggccctgggagtcgccctggacctacttctgtgat
ttccaagacatctcccacgtggtgctgacagacagccgcgtcagcatccgccggcaggac
aaccagtgcctggagttcagcctgctttctcgggccagcgccttgtctttcgtggcgctg
gtggacggctacttccgcctaacggccgactccagccactacctgtgccacgaggtggcg
ccgccccggctggtgatgagcatccaggatggcatccacggacccctgctggatccgttt
gtgcaagcgaagctgcggccagaagacgggctgtacctcattcattggagcactaaccac
ctgtaccgcctcatcctcacagtggcccagcgtgactcggcacccggggtgcggggcttg
cgcctccggaagttccccatcctgcaagaggccggggcctttgtgctggagggttgggac
cgctcctttgccagcatcagggagctgcgggtggctttgcagggctgtgccctgcgggct
ggcgaggactgcttccccctgcgccgctgctgcctgccccgacctggagaaatctccaac
ctcctcatcatgcgggggtcgcggcccaacagccagccgcctaatctcagccagctcagc
ttccaccgggtgcatcaggacgagatcacccagctctcccacctgggccagggtacaaga
acgaacgtgtacgagggcctcctacgtgtgggggtccctgaggaggaggaggaggacaaa
gtggacagtgggatctccctggaaccatgtggaggccgtgggcaggagctacgcgtggtg
cttaaagtcctggaccccagtcaccacgacatcgccctggccttctacgagactgccagc
ctcatgagccaggtctcccatgcacacctggcctttgtgcacggcgtgtgtgtgcgtggc
tccgagaacatcatggtgacggagtacgtggaacacgggcccctggatgtgtggctgcgg
agagagcggggccacgtgcccatggcctggaaggtggcagtgacccagcagctggccagt
gccctcagctacctggaagacaagagcctggttcacggtaatgtgtgtggccgaaacatc
ttactagccaggccagggctggcagaggacaccagcccattcatcaagttgagtgaccca
ggcgtgggcctgggggcgctctccagagaggagcgcgttgagcgcataccctggacggct
cccgagtgcctgaccggcggagccaacagcctgagcaccgcggccgacaagtgggggttt
ggcgccaccctgcttgagatctgctttgatggggaagcccccctccagggccgtggcccc
tctgagaaagagcgtttctaccagaagcaacaccagctacccgagccctcgtgccctgag
ctggccacactcaccagccagtgcctgacctatgaacctgcccagcggccgtccttccgc
accattctgcgcgacctcactcggctgcagccccacaatctagtggatatctctaccgtg
aaccctgactccccggcctcggaccccacggtgttccacaagcgatatttgaaaaagatt
cgggatctgggcgaggggcacttcggcaaggtcagcctgtactgctacgaccccaccaac
gatggcaccggggagatggtggccgtgaaggccctcaaggcgggctgcgggccccagctc
cgctcgggctggcggcgggagatcgacatcctgcgcacgctctaccacgagcacatcgtc
aagtacaagggctgctgcgaggacccaggcgagaagtcggtgcagctggtcatggagtac
gtacctctgggtagcctccgggactacctgccccggcacagcgtcgggctggctcagctg
ctgctcttcgcccagcagatctgcaagggcatggcctacctgcacgcccagcactacatc
caccgagatctagccgcgcgcaacgtgctgctggacaacgacaggctggtcaagatcggg
gactttggcctagccaaggccgtgcctgaaggccacgagtactaccgcgtgcgcgaggat
ggggacagccccgtgttctggtacgccccagagtgcctgaaggagtgcaagttctactat
gcatctgacgtctggtcgtttggggtgacactctacgagctgctgacacactgtgactcc
agccagagccctccttcgaaattcttcgagctcatcggcctcacccagggccagatgaca
gtgctgagactcaccgagttattggaacgaggagagaggctgccgcggcccgacaaatgc
cccagtgaggtctatctcctcatgaagaactgctgggaactggaggcctccttccgcccg
accttccagaacctcattcccatcctcaagatggctcatgacaagtaccaggcccaggcc
ccttcggtgttcagtgtgtgctga
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