Dipodomys ordii (Ord's kangaroo rat): 106003227
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Entry
106003227 CDS
T07834
Symbol
Erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord01521
EGFR tyrosine kinase inhibitor resistance
dord01522
Endocrine resistance
dord01524
Platinum drug resistance
dord04010
MAPK signaling pathway
dord04012
ErbB signaling pathway
dord04020
Calcium signaling pathway
dord04066
HIF-1 signaling pathway
dord04151
PI3K-Akt signaling pathway
dord04510
Focal adhesion
dord04518
Integrin signaling
dord04520
Adherens junction
dord04530
Tight junction
dord05200
Pathways in cancer
dord05205
Proteoglycans in cancer
dord05206
MicroRNAs in cancer
dord05212
Pancreatic cancer
dord05213
Endometrial cancer
dord05215
Prostate cancer
dord05219
Bladder cancer
dord05223
Non-small cell lung cancer
dord05224
Breast cancer
dord05226
Gastric cancer
dord05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
106003227 (Erbb2)
04012 ErbB signaling pathway
106003227 (Erbb2)
04066 HIF-1 signaling pathway
106003227 (Erbb2)
04020 Calcium signaling pathway
106003227 (Erbb2)
04151 PI3K-Akt signaling pathway
106003227 (Erbb2)
09133 Signaling molecules and interaction
04518 Integrin signaling
106003227 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
106003227 (Erbb2)
04520 Adherens junction
106003227 (Erbb2)
04530 Tight junction
106003227 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106003227 (Erbb2)
05206 MicroRNAs in cancer
106003227 (Erbb2)
05205 Proteoglycans in cancer
106003227 (Erbb2)
05230 Central carbon metabolism in cancer
106003227 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
106003227 (Erbb2)
05226 Gastric cancer
106003227 (Erbb2)
05219 Bladder cancer
106003227 (Erbb2)
05215 Prostate cancer
106003227 (Erbb2)
05213 Endometrial cancer
106003227 (Erbb2)
05224 Breast cancer
106003227 (Erbb2)
05223 Non-small cell lung cancer
106003227 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
106003227 (Erbb2)
01524 Platinum drug resistance
106003227 (Erbb2)
01522 Endocrine resistance
106003227 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dord01001
]
106003227 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dord04147
]
106003227 (Erbb2)
04090 CD molecules [BR:
dord04090
]
106003227 (Erbb2)
Enzymes [BR:
dord01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
106003227 (Erbb2)
Protein kinases [BR:
dord01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
106003227 (Erbb2)
Exosome [BR:
dord04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
106003227 (Erbb2)
CD molecules [BR:
dord04090
]
Proteins
106003227 (Erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Tcell_CD4_C
Kinase-like
HGSNAT_cat
Motif
Other DBs
NCBI-GeneID:
106003227
NCBI-ProteinID:
XP_012893522
Ensembl:
ENSDORG00000014861
UniProt:
A0A1S3GZZ1
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLQLPTSPETHLQMLRHLYEGCQVVQGNL
ELTYLPANASLSFLQDIQEVQGYMLVAHSQVRQIPLQRLRIVRGTQLFEDNYALAVLDNG
DPLDSATPAMGVALGGLRELQLRSLTEILKGGVLIQRNPQLCYQETILWKDIFHKNNQLA
RTVIDTNRSRMCPPCASSCKDNYCWGESSSDCQILTGTICASGCARCKGRLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTSCP
YNYLSTDVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLRAARAVTSAN
IQEFAGCKKIFGSLAFLPESFEGIPTSNIAPLKPEHLQMFETLEEITGYLYISAWPDSLP
DLSVFQNLQVIRGRVLYDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNTHLCFIHTV
PWDQLFRNPHQALLHSGNRPEDACVGEGQACYHLCANGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVSDRHCLPCHTECQPQNGSVTCFGSEADQCEACANYKDPPFCVSRC
PSGVKADLSYMPIWKFPDEEGTCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIATVVG
VLLFVVVGVVLAILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAIPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVVEFSRMARDPQRFVVIQNEDLGTASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGTGGTTHRRHRSSSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGVGAAKGLQSLPQHDLSPLQRYSEDPTVPLPLEMDGYVAPLTCSPQPEYV
NQPEVRSQPTLPPEGPLSSVRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPR
GSTGTQPHPPPAFSPAFDNLYYWNQDRSERGPPPSTFEGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgcccttctgccccccggagcc
gcgggcacccaagtgtgcaccggcacggatatgaagctgcagctccccaccagtcctgag
acccacctgcaaatgctccgccacctctacgagggctgccaggtggtacagggcaacttg
gaactcacctacctgcccgccaatgccagtctctcctttctgcaggacatccaggaggtt
cagggctacatgctggtggctcacagccaggtgaggcagatcccgttgcagaggctgcgg
atcgtgcgaggcacccagctcttcgaggacaactatgcgctggccgtgctagacaacgga
gaccctctggacagtgccacccctgccatgggggttgccctaggagggctgcgggagctg
cagcttcgaagcctcacagagatcttgaagggaggagttttgatccagcggaacccccag
ctctgctaccaggaaaccattttgtggaaggacatctttcacaagaacaaccagctggct
cgcacggtcatagacaccaaccgctcccggatgtgcccgccctgtgcttcatcatgtaaa
gataactattgctggggagaaagttcttcggactgtcagatcttgactggcaccatctgt
gccagtggctgtgcccgctgtaaaggccggctgcccacagactgctgtcatgagcagtgt
gctgcgggctgcacaggtcccaagcactctgactgcctggcctgcctccacttcaaccat
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacagacaccttcgag
tccatgcccaaccctgagggccgttacacctttggcgccagctgtgtgacctcttgtcct
tacaactacctgtctacggacgtggggtcctgcacgctggtctgtcccccgaacaaccag
gaagtgacagccgaggatggaacacagcggtgtgaaaaatgcagcaaaccctgtgcccga
gtatgctacggtctgggtatggaacatctgcgggcagcaagggcagttaccagtgccaac
atccaggagtttgctggctgcaagaagatctttgggagcctggcatttttgccagagagc
tttgaagggatccctacttccaacattgcccccctgaaacctgagcacctccaaatgttt
gagaccctggaggagatcacaggttacctgtacatctcagcatggccagacagcctgcct
gacctcagtgtcttccagaaccttcaagtcatccggggacgcgttctgtatgatggcgcc
tactcgctaactctccaaggcctgggcatccgctggctggggctgcgttcactgcgggag
ctgggcagcgggctggccctcatccatcgcaacacccacctctgcttcatacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgcttcatagtggcaatcggcca
gaggatgcatgtgtgggcgagggccaggcctgttaccatttgtgtgccaatgggcactgc
tgggggccggggcctacccagtgcgtcaactgcagtcagtttctccggggccaggaatgt
gtggaggaatgccgagtcctgcaggggcttcccagggagtatgtgagtgacaggcactgt
ctgccctgtcatactgagtgtcagccccagaatggctcagtgacttgctttggatcggag
gcagaccaatgtgaggcctgtgctaactacaaggatcctcccttctgcgtgtcccgctgc
cccagtggtgtgaaggctgacctctcctacatgcccatctggaagttcccagatgaagaa
ggcacgtgccagccgtgccccatcaactgcacacactcctgtgtggacctggatgacaag
ggttgccccgcagagcagagagccagccctgtcacatccatcatcgctaccgtggtgggt
gtcctgttgttcgtggtcgtgggagttgtccttgcgattctaatcaagcgaaggcgccag
aagatccgaaagtacacaatgcggaggctgctgcaggaaaccgagttggtggagcctctg
acacccagtggagcaatacccaaccaggctcagatgcggatcttgaaagagactgagcta
aggaaggtgaaggtgcttggatctggagcttttggcacagtctacaagggcatctggatc
ccagatggagagaacgtgaaaatccctgtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcttatgtgatggctggtgtgggctcccct
tatgtgtctcgcctcctgggcatctgcctgacttccacggtgcagctggtgacacagctt
atgccctatggctgccttttggaccacgtccgagaacaccgagggcgcctgggctctcag
gacctgctcaactggtgtgtgcagatagccaagggcatgagctacctggaggatgtgcgg
ctggtacacagggacctggctgcccgcaatgttctggtcaaaagtccaaatcacgtcaag
attacagacttcgggctagctcggctgctggacattgatgagactgagtaccacgcggat
ggtggcaaggtgcccatcaagtggatggcattagaatccattctccgccggcggttcacc
caccagagtgacgtatggagctatggtgtgactgtgtgggaactcatgacttttggagcc
aaaccctatgatggaatacctgcccgggagatccctgacctgctggagaagggggagagg
ctgccccagccccctatctgcaccattgacgtctatatgatcatggtcaaatgttggatg
attgattctgaatgccggccaagattccgggagttggtggttgaattttctcgcatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggtacagccagtcccttg
gacagcaccttctaccgctcactgctggaggatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccaacagggtttcttctgcccagaccctgctccaggcacaggg
ggtaccacccaccgcaggcatcgaagctcatccaccaggagtggaggtggtgagctgacc
ctggggctggagccttctgaagaagaaccacccaggtctccactagccccctcagaaggg
gctggctctgatgtattcgatggtgacttgggggtaggggcagctaaggggttgcagagc
ctcccccaacatgacctcagccccctgcagcggtacagtgaggaccccacagtgcctctg
cccctggagatggatggctacgttgctcccctcacctgcagcccccagccagaatatgtg
aaccagccagaagttcggtcacagcctaccttacccccggagggtcctctttcttctgtc
cgacctgctggtgccactctggaaaggcccaagactctctcccctgggaagaatggggtt
gtcaaagacgtttttgcctttgggggtgctgtggagaacccagagtacttggcacctcgg
ggaagcactggtacccaaccccaccctcctccagcattcagcccagcctttgataacctc
tactactggaaccaggaccgatcagaacgagggcctccacccagcacctttgaagggacc
cctacagcagaaaaccccgagtacctgggcctggatgttccagtgtga
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integrated database retrieval system
