Drosophila pseudoobscura: 4802698
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Entry
4802698 CDS
T01032
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
dpo
Drosophila pseudoobscura
Pathway
dpo00280
Valine, leucine and isoleucine degradation
dpo00640
Propanoate metabolism
dpo00785
Lipoic acid metabolism
dpo01100
Metabolic pathways
dpo01210
2-Oxocarboxylic acid metabolism
Module
dpo_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dpo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
4802698
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
4802698
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
4802698
Enzymes [BR:
dpo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
4802698
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GFIT
Motif
Pfam:
E1_dh
Transketolase_N
DXP_synthase_N
DUF6409
Motif
Other DBs
NCBI-GeneID:
4802698
NCBI-ProteinID:
XP_001359565
UniProt:
A0A6I8UR49
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All DBs
Position
2:24922208..24924046
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AA seq
439 aa
AA seq
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MSFLRKSVKLLNAAAGRQQNLKAIVGSTLRHQRTYSSEPPNDYANFPGAKAPFVSKLKLN
MPEDYAPIPIYRVMDRDGFIADETQDPQLGREVVEKMFRDMLLLNTMDKILYESQRQGRI
SFYMTNFGEEASHIGSAAALEMRDLIYGQYREAGVLVWRGFRIDQFIDQCYGNVDDLGRG
KQMPVHYGSRELNFVTISSPLSTQMPQAVGAAYAMKMRPNNDACVVCYFGEGAASEGDAH
AAFNFAATLNCPVILFCRNNGFAISTPSHEQYRGDGIAGRGPMGYGIATIRVDGTDVFAV
YNAMKEAREYVLRENKPVVFEALAYRVGHHSTSDDSTAYRSTEEIEVWNSVEHPISKLKR
YMVHKGWFDEAEETAYIKEVRKKVLKQIAVSEKKLKPNWKEMFEGVYAEMPEHLVEQQRE
LQEHIEAHKDSYPLKDFKQ
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
atgtcattcctgcgcaaatcagtcaaactgttgaatgcagcagcggggaggcagcaaaat
ctcaaagcgattgttggatccaccttgcggcatcagcggacttacagctctgaaccgcca
aatgattatgccaattttcctggagccaaggccccgtttgtaagtaaactgaagctaaat
atgccggaggattatgcgcccatacccatttaccgcgttatggatcgcgatggtttcatt
gccgatgaaacgcaagatccccagctaggccgcgaggtggtggagaagatgttccgcgac
atgctgctgcttaatacaatggataaaatcctatatgaatcgcagcgccaggggcgcata
tcgttctacatgaccaattttggcgaggaagcctctcacatcggcagtgcggccgctttg
gagatgagagacctcatctatggccaatatcgtgaggccggtgtgctggtctggcgtggc
ttccgcattgatcagttcatcgatcagtgctatggcaacgtagatgatttgggtcgtggc
aagcaaatgcccgtacattatggctccagagagctgaactttgtcaccatctccagtcca
ttgtccactcaaatgccacaggctgtgggtgccgcctatgcgatgaagatgcgaccgaac
aacgatgcttgtgtggtctgctactttggggagggtgcggcgtcggagggagatgctcat
gcggccttcaatttcgctgcaacgctgaactgccccgtcattctcttctgtcgcaacaat
ggctttgccatatcgacgccctcccatgagcaatacagaggcgatggtatagctggtcgt
ggtccgatgggctatggtattgccaccattcgtgtggatggcaccgatgtctttgccgta
tacaatgccatgaaagaagctcgagagtatgtgctgcgtgagaacaagccggtggtgttt
gaggccttggcgtaccgtgtgggacatcattccacctcggacgacagtacagcataccgg
tcgacagaggaaatagaggtttggaactccgtagagcacccgatctcgaagcttaagcgc
tacatggtacacaagggctggttcgatgaggcggaggaaacagcatacatcaaggaagtg
cgcaagaaggtactcaagcagattgctgtgtctgagaagaagctaaaacccaactggaag
gagatgttcgagggcgtgtacgccgagatgcccgagcatttggtggaacagcagcgcgag
ctccaggagcatatagaggcgcacaaggacagctatcctttgaaggactttaagcagtag
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