Drosophila pseudoobscura: 4816331 Help Entry 4816331           CDS       T01032                                  Name (RefSeq) protein purity of essence   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism dpo  Drosophila pseudoobscura Brite KEGG Orthology (KO) [BR:dpo00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:dpo04121]     4816331 Enzymes [BR:dpo01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      4816331 Ubiquitin system [BR:dpo04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     4816331 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Htt_N-HEAT_1 Poty_PP LEDGF Motif Other DBs NCBI-GeneID:  4816331 NCBI-ProteinID:  XP_001355926 UniProt:  Q29L39 LinkDB All DBs Position 4:complement(8523413..8541235) Genome browser AA seq 5381 aa AA seqDB search MSSHSGGTDWNSVIKALLLSRTGALNKNEVVNLLKAITRCEHEFFDDEGSFVPFYTAFAA LAADKLMQIKSICQTQICQLHDATAVLIRFILFRLPKVSVFESKWLLAALKMLCEGRENA SSAVAQFDYSAVAGVVKSSKHPESSNKSIMSMAGSTTGGAGAGGSNDKESPKLEIKRSRS DLSSVILQQLLAPLEPGKMTWVPLSEEITDCTEQLLAANVEVFQEANGVDTLLDICVGLP ILSRYRMKYMETINAGKPLYLPLTQAEATTVKSSMNHMLTDLSIVGQAYALIVMQPLTPS RIEKLSMCGISALYNAVLTSIATSVLSMGQASSAQKQQQQQTAAAASTSQGSGGGLSSVQ TSKDHDEFEEQASGIVNKALEIYSSIGEMFKSSARMYIYQNHLCYGSWLLISGIQGAMGA SGSASAETAAKAAAATKVASKTESITAPSTPIARVNLFKVQQGFGELNAAIANHSIKLLS ELIEDLKIESACGQSSVTDPETLPEPAQFDILQNYTSLERIVRVLNTATLHQLFTFLATV AYRKACTLKRASTKDRTECDPISYSDSTTCLNESMSYSDNSEEDDSESYLGHWFKETLSP ETHDDNANTSSQERSGEQKSALVPKLDEPHEYLELSADIFCFLDQFLANRHAYMQRYVKA GVSDQQMLLMANIIKDFDRDVMRNDSEQQSPPSTAAAVAAATGAGSSGSSAKWQASMIRF SGAAGRYIHNLISTGLLSEQLQSNLLQHLAISPWSTDTNTWPLQVYPSTLSVLVQILLLK PIQEKEAACLSVWHRLINTLVDGVCSSSSAGDSDYEDINIEHAQLLLFLFHSLNLMQKKS ILLLTAGGVIRCAEVCRGISAERVVRNSQMMLLSRLLVFLEYLMKHLYHAPPELLDQVRW ILFSVSSMPETQKVSDLINSRTKLNSYCRQDIEEKFRKSSGEYGSNIRPTFYSLVVKEPE KAYWVSEFKLDGLAWNFILCTPDKLKYPLLVDALVDILNIADMSSFSRKENSESNSIHNL CAMQYCFTNTWKLLLGLPPSTSHVEALRIERAPNLHSLVWSTRLPLATSHYLIVNSLIKQ GMYTQYAESLYTQVGDTTADIRYNLKQTILGVEAFNQQMSNKGIPRLSELILFDALVAHM QAVAWAEKEGFKLLRKDCEDSSGGDQSSCTSAASSSGGNATDHDHPEVYSSNESIDEEKS KHEDDQGLSTETLQRNQMINELLIKLMDSYRYLSEIVREQMLKQLSSTTPEHVLNLIVPI VSDKPAIMLELHAAFLKLLPNEDKQLIANEWPKCLMVNDSAFDGKQHPVEPYTLNVIDAH ITELTRGSGGVAYSTLHTLKHCLKTILHLMELLLPFASNCSEMDAQLKPLLIASMLDMRT DYLQGQSEQCLREILSGLTLEAQKLLLYEHMIGYCYRMLIEFAAELRQPAAGGTPLDQER ALFNESMLFAVLKTFIKMLEKPTAVQAMRQFFHDQKTGSLTTLLLSFTGTTLPLSYARKM LQFVERLFEQSTRADSQFQHEDLVDCFSDLATVDVARLKLWLAHIIYGPNMTAGDVSNSE TMDPTCRLLTSIMQPSSSSSSNAQTPTNMATVSAMPSISDQLDAMDIDYDCGAAAGAAGA APNTSQILSLWQAAQPNPSEESSQACDHSEGGEQRQSERNGGLLLSITKYLVRDQSKAGP IAAPLFQALLQLGQTLISPPHDGCDFADVLQIMITLADASPARGHVALFNTTLLWLELAK LQLPDKHLRHAENVSALLRYLSELLQSIGYRGSRQHMPPWDDELQTDIDDLYDELAEEEQ DSLLDDSDEDTLNNKLCTFSQTQKEFMNQHWYHCHTCNMINTVGVCSVCARVCHKGHDVS YAKYGNFFCDCGAKEDGSCQALSRRLGSGEARESVGPGGSNSCSYLPSHMSLLASKKRIN TAPGATQQQHGAPARKDSISSERIQLLGKLLEPYRETLQHQEQWMLVVRCILEYFDVLLP SIRENCTLYSIVGCHRRATAALQRLHQLEQSFQITDQLMFATLGSQEGAFENVRMNYSGD QGQTIKHLLTSGTIRRVAFCCLSSPHGRRQQLAVSHEKGKVTILQLSALLKQADASKRKL TLTQLSSAPIACTVLSLAANPCNEDCLAVCGLKECHVLTFSSSGSTNEHIVITPQLENGN FLKKAMWLPGSQTLLAIVTTDYVKIYDLSVDTISPKYYYLVAVGKIKDCTFMYHQQNGSG SYFMLSFTSSGYIYTQQLDQQSLAVHGDFYVTNTLELSHQHIKDINGQVCGGGVSIYYSH ALQLLFYSYTCGRSFCSPLTNVNEGVKGIYHLDINNTAASTASKSSSASKVPLQSLVGWT EVAGHPGLIYASMHTSNNPVILMITPERIYMQEIKAQSAKSRIMDVVGIRHSVAGTEKTT LLLLCEDGSLRIFSAQPEHTSFWLSPQVQPFGNQLYSSTLLAKNTTNNPQGKSKGGGSAA AGKLLHRKASSQQHQKQLTSGGQPIFPIDFFEHCNMLADVEFGGNDLLQIYNKQKLKTRL FSTGMFVASTKATGFTLEVVNNDPNVVMVGFRVMLGTQDIQRAPVSVTILGRTIPTTMRK ARWFDIPLTREEMFQSDKMLKVVFAKSQDPEHVTLLDSIEVYGKSKELVGWPDDSEDVPA PSSGPTPVTATQQSAAANFGEGFNCITQLDRMVNHLLEVLDCALHLLGGSAVAAPLRSKV VKTASGLLLLPTPNPVQTQARYVLATLYGSRASYHSFKDGVILHFVHGELQAMQPKLQQL ESLQEIDPEAFYRLILLVRGVANSRPQSLAKICLENSYDLVPDLMRIVLELHKITPDLDE PVNIVRRGLCQPETIVHCLVEIMYGFALADPGQVGRMTQYFIDLLKHDATVISHSAKEAL ILLLSPRMKRRKVAAIAVITPPACSTPTPQMQALQAVAASAANDIIEEAAGVAAGQDQDN AAAALLEAVEGGLPGQQPNHQLLNLEAFMGGGFPRLLGLPEDGDDEAIMDIAIALSLQQH GGADANALHSLQQGLANIQGIRQAAANAAAASVSVSVSAGGSDDEGSNVATDGSTLRTSP AEPAGSGGSESGGSGVESIGGTSARSSNFGDHPNTTPPRQSCSSVKDGEPGEEQQPGPSG SGGSASVPGGGLSAMSSTEDNNEINEDEKLQKLHDLRIAVLESIIQHLGTFDLCNGLQAI PLIQVIHMLTTDLNGNNERDQQVLQELLQALVEYVEIGKRGAASRMENKCPGNEVRLALL SLFGVMMGKTKSKQTGTTSPPHQFKDNSSFVASTTANVLSKSGAFVYALEALNTLLVHWK TVLGDPYAPGQAAAPIASGGATSGPGVQLLKPVKHGPKPDISILIPQNYLKNYPDIFESY DGLLTEIIVRLPYQILRLSSAHPDNYDSSFCEAMTFTLCEYMMLNLNTLLRRQVRKLLMY ICGSKEKFRMYRDGHSLDAHFRVVKRVCSIVSSKTGAPYNANPPMLSYDSLVDLTEHLRT CQEISQMRTGNWQKFCVVHEDALAMLMEIACYQLDDGVSPIIIQLLQAAVCNMPANKQQQ QQQQPPPAVVSASSKLRSDREKSEDTDAYYSKFDPAQCGTFVHQIFRYACDALIIRFVRI FLLENNISQLRWQAHSFMTGLFEHANERQREKLLTIFWNLWPLVPTYGRRTAQFVDLLGY LTLTTRSITERLPEFVSRAVEVLRTQNELLCKHPNAPVYTTLESILQMNGYYLESEPCLV CNNPEVPMANIKLPSVKSDSKYTTTTMIYKLVQCHTISKLIVRIADLKRTKMVRTINVYY NNRSVQAVVELKNRPALWHKARSVSLQSGQTELKIDFPLPITACNLMIEFADFFETVSGS SENLQCPRCSAAVPAYPGVCGNCGENVFQCHKCRAINYDEKDPFLCHSCGFCKYAKFDFS MYARVCCAVDPIESAEDRAKTVLMIHTSLERADRIYHQLLANKQLLELLIQKVAEHRIND RLVEDNMASVHSTSQVNKIIQLLAQKYCVESRASFEELSKIVQKVKACRSELVAYDRQQQ DLPPSNLALVLGAENPTTNRCYGCALASTEQCLTLLRAMAYNYDCRMGLYSQGLVSELAE HNLRRGTPQIQNEVRNLLVVLTKDNAEACMHLLQLVTSRVKSALMGSIPLISLEAAVHQE MTLLEVLLSQDDLCWEYKLKVIFELFISNCKLPRGPVASVLHPCLRILQSLINPTISGSG SGGKPVSAIELSNIKLPEGNTIDYRAWLNSDQNHEYLAWSNRMPISHHQQDAPAGTKPKS SKQQQSAGTETPPRKTKEAARAAYLGEKFGKRWRSNVLDKQRVTKPLVFNAEWIQPLLFN ENSRFGRQLACTLLGGLARTHERKQQALNLLTSFLYHVGDAGEASNEYLALYRSIATESP WLQYLVLRGVLCKISSLLATEIAKVHCMEEHSLSSDLTLGYALRRYVELLWLFLECPNIR RTYKTRLLGPVLESYLALRSLVVQRTRHIDEAQEKLLEMLEEMTSGTEEETRAFMEILID TVDKTRMNDIKTPVFIFERLYSIIHPEEHDESEFYMTLEKDPQQEDFLQGRMLGNPYPSG EMGLGPLMRDVKNKICTDCELIALLEDDNGMELLVNNKIISLDLPVKDVYKKVWLAEGGD RDAMRIVYRMRGLLGDATEEFVETLNNKSQEAVDTEQLYRMANVLADCNGLRVMLDRIGS LQRISRQRELIQVLLKLFLICVKVRRCQEVLCQPEIGAINTLLKVLQMCLQSENDSIQSA VTEQLLEIMETLLSKAASDTLDSFLQFSLTFGGPEYVSALISCTDCPNVRNNPSVLRHLI RVLAALVYGNEVKMALLCEHFKDTLNFKRFDNERTPEEEFKLELFCVLTNQIEHNCIGGT LKDYIVSLGIVERSLAYITEHAPCVKPTLLRTDSDELKEFISRPSLKYILRFLTGLSNHH EATQVAISKDIIPIIHRLEQVSSDEHVGSLAENLLEALSTDAATAARVQQVRDFTRAEKK RLAMATREKQLDALGMRTNEKGQVTAKGSILQKIEKLRDETGLTCFICREGYACQPEKVL GIYTFTKRCNVEEFELKSRKTIGYTTVTHFNVVHVDCHTSAIRLTRGRDEWERASLQNAN TRCNGLLPLWGPSVLETTFSASMTRHSSYMQESTQRCDISYTSSIHDLKLLLVRFAWERS FHDDAGGGGPQSNMHFVPYLLFYSIYMLLSSRSAARDSKTVLAYLTAPPSEKWLECGFEV EGPLYMITISVTLHSRELWNKHKVAHLKRMLAVAQARHVSPSVLCKALLAPADRQVKDYS VYKPYLMMWAMIDMIYNILFKLVTMPKEEAWPVSLFDYIRKNDEAMLKSTDGILHILTEE LLPCTSFGEFCDVAGLLTLIEQPDSFIEDLLASLPSTTSSS NT seq 16146 nt NT seq  +upstreamnt  +downstreamnt atgtcgtcccatagcggcgggaccgattggaactccgtaataaaagcattgcttttaagc cgcacgggtgcattaaacaaaaacgaagtggttaatttgctaaaagcaataactagatgt gaacacgaatttttcgacgatgaaggcagtttcgtaccattttatacggcctttgcggca ctggctgccgacaaacttatgcaaatcaaatcaatttgtcagacacagatatgccagctg cacgatgccacggcagtgcttattcgctttatactcttccgtctgccaaaagtgtcggtc tttgaatcgaaatggctattggcagccctcaaaatgctctgcgagggcagggagaatgct tcttcggctgtcgcacagttcgactacagtgccgtggctggggtggtgaagagctccaaa cacccggaatcatccaataagagtattatgtcaatggcaggtagcaccacaggtggtgct ggtgctggcggcagcaacgataaagagtcaccaaaattggagattaaacgctcgcgctcg gacctatcatcggttatccttcagcagctgttggcgccgctggagccgggaaagatgacc tgggtgcccctcagcgaagagatcaccgactgcactgagcaacttttggcagccaatgtg gaggtgttccaggaggcaaatggcgtcgataccctgttggacatctgcgtgggcctgccc attctcagtcgctatcgcatgaagtacatggagacgataaatgctgggaaacccctctac ctgccactcacacaggcggaggccacaactgtgaaatcatcgatgaatcacatgcttaca gatctctcgattgtgggccaggcctatgctttgatagtcatgcagccgctgacaccgagc cgcattgaaaagctttccatgtgcggcatctcggcgctgtacaatgctgtcctcacctcg atagccaccagtgtcttgagcatgggccaggcgagcagcgcgcagaaacaacagcaacaa cagacggctgctgcagcgtccaccagccagggcagcggcggtggcttgtccagtgtccag acaagcaaagatcacgacgaatttgaagaacaggctagcgggattgtaaacaaagccctc gaaatctattcgagcattggcgagatgttcaaatcctcggccaggatgtatatatatcag aatcatttgtgctacggcagctggctgctcatcagcggcatccagggagccatgggtgcc agtggcagtgcctcggcagaaacggcagctaaagcggcagccgccacaaaagtagcatcc aaaacagagtcgattacagcgcccagtacaccaatagccagggtgaatctgttcaaagtc caacagggctttggagaattgaatgcagctattgccaatcacagcattaagctgctgtcc gaactgattgaggatctaaagattgaatccgcctgcggacagagcagtgtcacagatccc gaaacgctgccagagccagcgcaatttgatatcctgcagaattacacatcgctggagagg attgtgcgggtcctaaacactgccacgctgcatcagctgttcacttttctggccaccgtg gcctaccgcaaggcatgcactctgaagcgtgcttcaactaaagaccgcaccgaatgcgat ccgattagctattcggactccacgacctgcctgaatgagtccatgtcctattcggacaac tctgaagaagatgacagcgaaagctatctggggcattggttcaaggaaaccctctccccg gaaacgcacgacgacaatgccaatacttcgtcgcaagagcgcagtggagagcagaagagc gctttggtaccgaaactagatgagccgcacgagtatctggagctgtcggcagacatcttc tgcttcctggatcaattcctagccaaccgtcatgcctacatgcagcgctatgtgaaggca ggcgtcagcgatcagcagatgctgctgatggccaacataatcaaggactttgatcgcgat gtgatgcgcaacgacagcgaacagcagtcgccaccaagtacggctgctgctgtggctgct gccacaggagctggatcttctggttcctctgccaagtggcaggcgtcgatgatacgtttc tcgggtgctgctggccgatacatacacaacctgatctccacgggactgctctccgagcag ctccaatcgaatctgctgcaacatttggccatctctccgtggtccacggatacgaataca tggcccctacaggtctatcccagcactctttccgttcttgtgcagatactgctgctgaaa cccatacaggagaaggaggccgcctgcctgtcggtgtggcatcgcctgatcaacacgctg gttgatggcgtctgctcctcttcgtctgccggtgactcggactacgaggacatcaacatt gagcatgcccagctgctgctcttcctgttccactcgctcaatctcatgcaaaagaaatcc atcctgctgctaactgcgggcggggtgatacgctgcgccgaagtctgtcgcggcatcagt gccgagcgtgtcgtcaggaatagccaaatgatgcttctatcgcgcttgctcgtattccta gagtatctgatgaaacatctgtatcacgcaccgcccgaactgttggatcaagtccgctgg atactgttcagcgtgagcagcatgccggagacgcagaaggtctccgatttgatcaacagt cgtaccaaactgaactcgtattgccgtcaggatattgaagagaagttccgcaagtcttca ggagaatatggatcgaatatacggcccacgttttatagcctggtcgtaaaggagcccgaa aaggcctattgggtgagcgaattcaaattggacggcctggcctggaactttatactctgc acaccggacaaactcaagtatccgctgctggtggacgccctcgtggatatcctgaacata gcggacatgtcctcgttttcccgaaaggagaacagcgagagcaacagcatacacaatctg tgtgccatgcagtattgttttaccaacacctggaaactgctgctgggcctgcccccatcc acctctcacgtggaggcgctccgcattgagcgggcacccaatttgcattcgctggtgtgg agcacacgcctgcccttggccacgtcacattatctgattgtcaatagcctcataaagcag ggcatgtacacacagtacgcggagtcgttgtacacccaagtgggggataccacagccgat atacgatataatttgaagcaaacgatccttggtgtagaggccttcaatcagcagatgagt aacaaaggtattccacgcctctcggaactcatactctttgatgccttggtggcccacatg caggccgtggcctgggccgaaaaggagggcttcaagctgctgcgcaaggactgcgaggat agcagcggtggcgaccaatcatcgtgcaccagtgcggcctccagtagtggtggcaatgcc acagaccatgatcatcccgaggtgtattcctccaacgaatccatcgatgaagagaaatcc aagcacgaggatgaccagggtctatccacggaaacgctgcaacgcaatcaaatgatcaac gagctgctgatcaagctaatggactcgtatcgctacctatcggagattgtgcgcgagcaa atgctcaagcagctgtcgagcaccacgccagagcatgtcctcaacttgatagtgcccatt gtgagcgataagccggccataatgctggagctgcatgcggcattccttaagctgctgccg aatgaggataagcagttgatagccaatgaatggcccaagtgtttgatggtcaatgattcg gccttcgatggaaaacagcatcccgtggagccatacaccctgaatgttattgatgcacac attacagagctgaccagaggcagcggcggtgtggcctattccactttgcatacgctcaaa cactgcctgaagacgatactccatttgatggagctgctgctgcccttcgcctccaattgc agcgaaatggatgcccagttgaagccgctgctgattgcctcaatgctggacatgcgcacc gactatctgcagggccagagcgagcagtgtctgagggaaatcttgagcggactgacccta gaggcgcagaaactgttgctgtacgagcacatgattggctactgctatcgtatgctgatc gaatttgccgcagaattgcgacagccagcggcgggaggcaccccattggatcaagagaga gccttgttcaatgaatcaatgctgtttgctgtcctaaagacattcatcaagatgctggag aagcccacagctgtgcaggccatgcgccagttcttccatgaccagaagacgggcagcttg accacgctgctgctgtcctttacgggtaccacgctgcccctgagctatgcccgcaaaatg ctgcagtttgtcgaacgtttgtttgagcaatccactcgagcggactcccagttccagcat gaggacttggtggattgtttcagcgatctagccacagtcgatgtggcacggctgaagctg tggctggcccacataatctatggcccaaatatgacggcaggcgatgttagcaactccgag accatggatccgacatgccgcctgctcacgagcatcatgcagccttcaagcagctccagt agcaatgcccagacacccacaaacatggccacagtgtcggctatgcccagtatctccgat cagctagatgccatggacatagattacgactgcggggcagcagcaggagcggcaggagct gcacccaacacttcacagatcttgagcctgtggcaggcagcacagccgaatccctcggag gagtcctcacaggcctgcgatcacagcgaagggggagagcaacgccaaagcgaacgcaat ggaggactactgctgtccatcaccaagtacctagtacgcgatcagagcaaggcaggaccg atagcagcacccctcttccaggccctcctacagctgggtcagactttgataagcccgcct cacgatggctgtgactttgcggatgtcctacagataatgatcaccctggcggatgcctct ccagcacgcggacacgtggcgctgttcaatacgacgctgctgtggctggagctggccaaa ctgcagctccccgacaagcatttgcgacacgcggaaaatgtgagcgccctgctgcggtac ctcagcgaactgttgcagagcattggctaccgtggcagtcgccagcatatgcccccatgg gacgacgaactgcagacggacattgacgatctgtacgatgagctggccgaagaggaacag gactcgctgctggatgactccgatgaggacacgctgaacaacaagctgtgcacattctcg cagacccaaaaggagttcatgaaccagcactggtaccactgtcacacctgcaacatgatc aacacggtcggcgtgtgctctgtgtgtgcccgagtgtgccacaaggggcacgatgtgagc tatgccaagtacgggaactttttctgcgactgtggtgccaaggaggatggctcgtgtcag gcgttgagtcgcagattgggctctggagaggcacgcgagtcggtgggacctggcggcagc aacagctgcagctacttgccctcgcacatgagtctcctggcgagtaagaagagaatcaac acagcaccaggagccacacagcagcagcatggagcgcctgcccgcaaggattcgatcagc agtgagagaatccagcttttggggaaactcctcgaaccctaccgtgagacgttgcagcat caggaacaatggatgctcgtggtccgatgcatactcgagtactttgatgtgctgctgccg tcgataagggagaactgcacgctctactcgattgtgggatgccacaggcgtgccactgcc gccttgcagcgtctgcatcagctggagcagagtttccagatcaccgatcaactgatgttc gccactctgggctctcaggagggggcctttgagaatgtgcggatgaattactccggagat caggggcagaccatcaagcacttgctgacctctggcacgatacgccgcgtggccttttgt tgcctgtcctcgccgcacggacgccgccagcagttggccgtgtcgcatgagaagggaaag gtcaccatactgcagctatcggcgttgctcaagcaggcagatgcctccaagcggaagttg actctcacgcaactcagttccgcgcccattgcctgcactgtgctctcgctggcggccaat ccctgcaatgaggactgcctggccgtgtgtggactgaaagagtgccatgtgctgaccttc tcgagcagcggcagcaccaatgaacacattgtcatcacgccccaattggagaatggcaac ttcctgaagaaggccatgtggctgcctggctcccagactctgctggccattgtcaccacg gattacgtgaagatttatgacctgtcggtggacacaatcagtccgaagtactactatctc gtggctgtgggcaagatcaaggactgcacgttcatgtaccatcagcagaatggcagcggg agctatttcatgctcagttttaccagctctggctacatctatacgcagcagctggatcag cagagcctggccgtgcacggcgacttttatgtgacaaataccctcgagttgagccatcag catatcaaggatatcaatggacaggtgtgcggcggtggtgtgtccatctattactcgcac gcgctgcagctgctcttctacagctacacctgcggcaggagcttctgttcgcccctgacg aacgtaaacgagggtgtcaagggcatctatcatttggacatcaacaacacagcagcatcg acggccagcaaatcatcgtcggcttcgaaggtgccgctccagtcgcttgtgggttggaca gaggtggccgggcatcccggactgatctatgccagcatgcatacgtccaataatccagtg atactgatgatcacacccgaacgcatatacatgcaggagatcaaggcacagtcggccaaa tcgaggataatggatgtggtgggcatacgccatagcgtggcggggactgagaaaaccacc ctactgctcctgtgcgaggacggcagcctcaggatcttctcggcccagccagagcacacg agtttctggctgtcgccgcaggtgcaacctttcggcaatcaattgtacagctccacgctg ctggcaaagaataccacaaacaatccgcagggcaaaagcaagggaggcggctctgcagcg gctggaaagctgctccatcgcaaggccagcagccaacagcaccagaagcaactgacatct ggaggccaacccatcttcccgattgatttctttgagcattgcaacatgctggcggacgtg gagtttggcggcaacgatctcttgcagatctacaacaaacagaagctcaagacgcgcctc ttctccacggggatgtttgtggccagcacaaaggccacgggattcacactggaggtggtg aacaacgatccaaatgtggtcatggtgggcttccgtgtgatgctgggcacccaggatatc caacgggcacccgtatcagttacgatccttggacgcaccatacccacaacgatgaggaag gcgcgatggtttgatataccgctgacgcgcgaggaaatgttccaatcggacaaaatgctg aaggtggtgtttgccaagtcgcaggaccccgaacatgtcacactcctggactctatcgag gtctatggcaagtcaaaggagctcgtgggctggcccgacgatagcgaagacgtaccggca cccagctctggtccgacgcccgtgacggccacgcaacagagtgccgccgccaactttggc gagggcttcaattgcatcacccagctggatcgcatggttaaccatctgctggaggtgctg gactgcgccctgcatctgctgggcggcagtgccgtggctgccccactgcgctcgaaggtc gtgaagacagccagcggactgctgctgctgcccacaccgaatcccgttcaaacccaggcc cgctatgtgctggccaccctctatggcagtcgggcgtcctatcacagcttcaaggatggc gtgatcctgcacttcgtgcacggcgaactgcaggccatgcagccgaagctgcagcaacta gaatctctgcaagaaatcgatccggaggccttctatcgcctgatattgctggtacgcggc gtggccaactcccgtccccagtcactggccaagatctgtctggagaacagctacgatttg gtgcccgacctgatgaggattgtcctggagctgcacaagatcacccccgatctggacgag ccagtgaatattgtgagacgcggcctgtgccagccggagaccatcgtccattgtttggtg gagattatgtatggctttgcattggccgatcccggtcaagtgggtcgcatgacccagtac ttcattgatctgctcaagcacgatgccaccgtgatcagtcacagcgccaaggaggcactg atccttctcctcagtccacgcatgaagcgccgcaaggtggcggccatagccgtcattacg ccgcctgcctgctccacgcccacgcctcaaatgcaggccctgcaagcggtggctgcatcg gcggccaacgacatcatcgaagaggcagcaggcgtggctgccggacaggatcaagacaat gcagcggccgctctgctcgaggcagtggagggaggactccccggacagcagccgaaccac cagctgctcaatctggaggcgttcatgggcggcggtttcccccgattgctgggtctaccc gaagatggcgacgacgaggccatcatggacatagccattgccctgagtctccaacagcat ggcggagccgatgccaatgccctgcattctctgcagcagggattggccaatatccagggc atcagacaggcggcagccaatgctgcagcggccagtgtttcggtctctgtgtctgcggga ggctccgatgatgagggctccaatgtggccaccgatggctccacgctgcgcacctcaccc gcagagccggcaggcagtgggggatccgagagcggtggcagtggtgtggagagcattggc ggcacatcggcgcgcagcagtaactttggcgatcatccgaatacaacgccaccgcgacag agttgcagttccgtcaaggatggagagccgggcgaggagcagcagccaggacccagtggc tctggtggctctgcctctgtcccaggaggtggcctgagcgccatgagcagcaccgaggac aacaacgagatcaacgaagatgaaaagctgcagaaactgcacgatttaaggattgctgtt ttggagagcattatccagcacttgggcacattcgatctgtgcaatggtctgcaggccata ccgctcatccaggtgatacacatgctgaccacagatctcaatggcaacaacgaaagggac cagcaggtgctccaggagctgcttcaggctctagtggagtacgtggaaataggcaaacgt ggagcggcctcaaggatggagaacaaatgtcccggaaatgaagtacgccttgctctattg tcgctctttggtgtgatgatgggcaagaccaaatcgaagcaaactggcaccacctcgcca ccgcatcagttcaaggataacagctcatttgtggccagcaccacagcgaatgttctgagc aagagtggggcctttgtctatgctttggaggcactcaacacgctcctcgtgcactggaaa accgtgctaggggatccctatgcgccaggccaagccgcagcaccgatcgcgagtggggga gccacctcgggaccgggcgtacagctgctcaaacccgttaaacacggccccaaaccagat atatccatactgataccgcagaactacctgaagaactatccagatatctttgagtcgtac gacggactgctcacggagatcattgtgcggctgccctaccagattctgcggctaagcagc gcccatccggacaactacgacagcagcttctgtgaggccatgacatttaccttgtgcgag tacatgatgctcaatctgaatacactgctgcgaaggcaggtgcgtaagctgctgatgtac atttgcggcagcaaagagaagttccgcatgtaccgcgatggtcactcgttggatgctcat ttccgtgtggtcaagagagtgtgcagcattgtaagcagcaagactggtgccccgtacaat gccaatccgccaatgctcagctacgactcgttggtggatttgacagagcatctgcgcacc tgccaggagatcagccaaatgcgcactggcaattggcaaaagttctgtgtggttcatgag gatgccttggccatgctaatggagattgcctgctatcagctagatgatggcgtgtctccc attattatacagctgctgcaggcggccgtttgcaatatgccagccaacaagcagcagcag caacaacagcagccaccgccagcagtcgtgtcggcgtcttcgaagctgcgcagcgatcgt gagaaaagcgaggacaccgacgcctactattcgaaattcgatccggcacagtgcgggaca tttgtccatcagatatttcggtatgcctgcgatgctttgatcatacgcttcgtaaggatc ttcctgctggagaataatatcagtcagctgcgctggcaggcgcactccttcatgacgggg ctgttcgagcatgccaacgagcgacagcgcgagaagctgttgaccattttctggaacctg tggcccctggtgcccacctatggccgaaggacagcacaatttgtggatctattgggatac ctcactctgacaacacgcagcataaccgaacgcctgccagagtttgtctcgcgggcagtc gaagtactccggacacagaacgagctgctgtgcaagcacccgaatgcccccgtctacacc accctggagtcgatactgcagatgaacggatactatctggaatcggagccctgtttggtg tgcaacaacccggaggtgccgatggccaacatcaagctgccgtcggtcaagtccgactca aaatataccaccacaacgatgatctacaagctggtgcagtgccacaccatctcgaagctg attgtgcggattgcggatctgaagcgcacgaagatggtgcgcacgatcaatgtgtactac aacaatcgcagtgtccaggcggtggtcgagctgaagaaccgccctgcgctgtggcacaag gcccgctccgtttcgctgcaatcgggacagacagagctgaagattgatttcccattgccc atcacggcctgcaatctgatgattgaatttgcggacttctttgagactgtgagcggttcc agcgagaatctgcagtgtccgcgctgcagtgccgctgtgccagcgtatccgggcgtgtgc ggcaactgcggggagaatgtgttccagtgccacaagtgtcgggccatcaactatgacgaa aaggatccgttcttgtgccactcgtgtggcttctgcaagtacgccaaattcgattttagc atgtatgcacgcgtctgctgtgccgtggatccgatcgaatcggccgaggatcgagccaag actgtattgatgatacacacctcactggagcgtgcggatcgcatctaccaccagctgttg gccaacaaacagcttctcgagctgctcatccagaaggtggccgagcatcgcatcaatgat cgtcttgtcgaggacaacatggccagtgtgcatagcacttcacaggtgaacaagatcatc cagctgctcgcccagaaatactgcgtggaatcacgcgccagcttcgaggaactaagcaag attgtccagaaagtcaaagcctgccgcagcgagctggtggcctacgatcgccaacaacag gatctgccgcccagcaatctggctttggtcttgggcgccgagaatcccacaacgaaccgt tgctatggctgcgccttggcctccactgagcagtgccttaccctgctgcgggccatggcc tacaattatgactgtcgcatgggtctctatagccagggactggtcagcgagctggcggag cataatctgcgccgtggaacaccgcagatccagaacgaggtgcgcaatctactggttgtt ttgaccaaggacaatgccgaggcgtgcatgcatctgctgcagctggtcacgtcgcgtgtg aagagcgctttgatggggtccattcccctgattagtctggaggcagccgtgcatcaggag atgacgctgctggaggtgcttctcagccaagatgatttatgctgggaatacaagctgaag gtgatctttgagctgtttatcagcaattgcaagttgccccgtggaccggtggcttcagtg ctgcatccctgcctgcgcattctgcagagtctgattaatcccacgatctctggcagcggc agcggcggcaagccagtatctgccattgagttgagcaacattaaactgcccgaaggcaac accatcgactatcgggcgtggctcaactcggatcagaatcacgagtacttggcctggagc aatcgcatgcctatcagccaccaccaacaggatgcaccggcaggcaccaagccaaagagc agcaaacagcagcagtcggcgggcacggagacaccgccaagaaagaccaaggaagccgcc agggcggcatatttgggcgagaagtttggcaaacgctggcgttcgaatgtgctggacaag cagcgtgtgaccaagccgctggtgttcaatgcagagtggatccaaccgttgctcttcaac gaaaactcccgctttggccggcaactggcgtgcacgctgctcggaggactggcacgcacg cacgaacgcaagcagcaggctctcaatttgctcacgtccttcctgtatcatgtgggggac gcgggagaggccagcaacgagtatttggctctctaccggagcattgccaccgagtcgccc tggctgcagtatttggtactgaggggagtgctgtgcaagatctcgtcgctgctggctacg gagatagccaaagtgcattgcatggaagagcattcgctgtcctcggacctgacgctcggc tatgctttgcgccgatatgtggagctcttgtggctcttcctcgagtgccccaacatacgc aggacctacaagacccgtctgctgggcccagtgctcgagagctacttggctctgagaagt ctggtggttcagcgaacccgacacattgacgaggcgcaggagaagctgctcgaaatgctg gaggagatgaccagcggcaccgaagaagagacgcgtgcctttatggagattctcattgat acggtcgacaagacgcgcatgaatgacatcaagacgccggtgtttatctttgagcgtctg tattcgatcatacatccggaggagcacgacgagagcgagttctacatgaccctggagaag gatccacagcaggaggacttcctgcagggccgcatgctcggcaatccctatccctccggc gaaatggggctgggccccctgatgcgagatgtaaagaacaaaatctgcacggactgtgaa ttgattgctctgctggaggatgacaacggcatggagctgctggtgaacaataagatcata agcttggacctgcccgtcaaggatgtgtacaaaaaggtgtggctggccgagggcggcgat cgcgatgccatgcgtattgtctatcgcatgcgcggactgctgggcgatgccaccgaggag tttgtcgagacgctgaacaacaagagtcaggaggcggtggacacagagcagctataccgc atggccaacgtactggccgattgtaatggccttcgtgtgatgctggacaggattggcagt ctgcagagaatctcccgccagcgtgaacttatccaggttctgctcaagctcttcctcatc tgtgtaaaagtgcgccgctgccaggaggtcctgtgccagcccgagattggggccatcaat acactgctgaaggtgctacagatgtgcctgcaatcggagaatgactcaatacagtcggca gtcaccgaacaactactggagattatggaaacgctgctctcgaaggcagctagtgatacg ctggactcgttcctgcagttctccctgacgttcggagggcccgagtatgtgtcggcattg atctcctgcacggattgtccgaatgtacgcaacaatccttcggtgttgcggcatctcatt cgtgtgctggccgccctggtctacgggaatgaggtgaagatggccctgctgtgtgagcat ttcaaggacacactcaacttcaaacgctttgacaacgaacgcacacccgaggaggagttc aagcttgagctcttctgcgtcctgaccaatcagatcgagcacaattgcattggcggcacc ctcaaggattacattgtcagtctgggcattgtggagcgctcgttggcctacatcacagag catgccccatgtgtgaagcccacactcctgcgcaccgactccgacgagctgaaggagttc atttcgcgccctagtctcaagtatatactgcgcttccttaccggactctccaatcatcac gaggccactcaggtggccatcagcaaggacattataccgattatacatcgcctagagcaa gtgtccagcgatgagcatgtcggcagtctggccgagaatcttctagaggctttgtcaacc gatgcagccaccgcggcccgagtccagcaagtgcgtgacttcacgcgcgccgaaaagaaa cgtctggccatggccacgcgcgagaaacaactggatgccttgggtatgcgtacgaacgag aagggacaggtgacggccaagggctctatactgcaaaagatcgagaaactgcgcgacgag actgggctgacgtgtttcatctgccgcgaggggtatgcctgccagcccgaaaaggtgctg ggcatctatacgttcaccaagcgctgcaacgtggaggaattcgagctgaagtcccgcaaa accattggctacaccacggtgacccatttcaatgtggtccatgtggactgtcacacctca gcgattcgtttgacccgcggccgtgatgaatgggagcgggctagtctgcagaatgccaat acccgatgcaatggtctgctgccgctctggggcccgtccgtgctcgagacgaccttctcc gcttcgatgacgcgtcacagcagctacatgcaggagagcacccagcgttgtgacatctcc tacacgagcagcatacacgacctgaagctgctgctggtgcgtttcgcctgggagcgtagc ttccacgatgatgccggcggcggtggtccccagtccaatatgcactttgtgccctacctg ctcttctattcgatctacatgctgctgtcctcgcgctcggcggccagggatagcaagacg gtactcgcctatctaacagccccgcccagcgagaagtggctcgagtgtggcttcgaggta gagggaccgctgtacatgatcaccatttcggtgacgctgcacagtcgcgagctgtggaac aagcacaaggtggcgcatctgaaacgaatgctggccgtggcccaggcacgacacgtctca ccatcggtgctgtgcaaggctctgcttgcgccggccgatcgccaggtgaaggattacagt gtgtacaagccgtacctgatgatgtgggccatgatcgatatgatatacaacatcctgttc aaattggtgaccatgcccaaggaggaggcctggccagtttccctgttcgattacatacgc aaaaatgacgaggctatgcttaagtcaacagatggcatcctacacatcctgactgaggag ctattgccgtgcacttcgtttggcgagttctgcgatgtggcaggacttctaactctgatc gaacagccggacagcttcatcgaggatctgctggcctccctgccttcgaccacaagttct agttaa

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