Dreissena polymorpha (zebra mussel): 127870859 Help Entry 127870859         CDS       T08834                                  Name (RefSeq) ryanodine receptor-like   KO K04962   ryanodine receptor 2 Organism dpol  Dreissena polymorpha (zebra mussel) Brite KEGG Orthology (KO) [BR:dpol00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:dpol04040]     127870859    04990 Domain-containing proteins not elsewhere classified [BR:dpol04990]     127870859 Ion channels [BR:dpol04040]  Voltage-gated cation channels   Ryanodine receptor    127870859 Domain-containing proteins not elsewhere classified [BR:dpol04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    127870859 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_1 EF-hand_7 EF-hand_5 EF-hand_6 EF-hand_8 GCIP_N Motif Other DBs NCBI-GeneID:  127870859 NCBI-ProteinID:  XP_052269357 LinkDB All DBs Position 3:106853843..107056975 Genome browser AA seq 5286 aa AA seqDB search MAEPGDAVSSEQDDISFLRTNDMVCLSCVTATTRDSPSERVNLAAEGFGNRMCFLENVSS KDIPPDISMCVFVLEQALSVRALQEMVTSSSQDSSAAQSGHRTLLYGHAVLLRHLPSNMY LSCLSTSSSNDKLAFDVGLNESSQGESCWWTIHPASKQRSEGEKVRVGDDLILVSVSSER YLHIGSSSEVIASFQQTLWTVVPMSSGVIRVKSMGFVFGGDVLRLFHGHMDECLTIPEAG SDSEFNCVMYETGAVCSHARSLWRLEFIKTKWAGGFMGWGQQVRIRHVTSGRYLGITHDH NVVTVHRGKADEDTTSFYLRQTKDDKKLAEGHEDEGMGKCDLKYGDSVVFIQHCATGLWL SYQTFETKKRGVGRVEEKKAVMLVEGHMDDGITLSRAQEEESRSARVIRKCQSLFNRFNK ALDLLRSEGRTCIAWSRIRLSEVVKCLTDLIDYFQQPAVDEEHEEKQNKLRALRNRQDLF QEEGMIALILETIDKFGQYKGKRQFAHYAGEEAANKWDDISSYLYLLLAAMIRGNRANCA QFAQSYRLDWLVHRLESQMSSKGVLDVLHCVLIDSPEALNMIKEKHIITIISLIDKHGRD PKVLNVLKSLCVGNNVAVRTNQNLICENLLPGRDLLLQTKLVDHVFSMKPNIYVGLCEGS SMYRRWYFEVVVDQFEAGSHLPPLLRIGWASSSGFVPYPGGGQGWGCNAAGDDLYSFAFD GNCFWTGAKRKQVRDLSLIFRKGDVVGCLLDLTGPKISFTINGAPVMGLFKDFNLDGLFF PVISMTACVSCRFVLGSEHGKLKYGPPEGHSPAIESLLPKQKLKIEPCFYFGDVQKNIIS GPTEVLDYAPFVPQPVDTGNVQLPVYVECVRDKLAENLHEVWAMNKIDQGWSWGEIREDT RKKNPSLTSFEKLPMSEKKYVVTVAFETLRTLLALGYHVSMEMKDSKTNRMKTVKLSSDF LQSNGYKPMPLDLSGTELDEKMCDLVELLAENTHNVWAKDRIKNGWTYGLCEDLATKRSP HLVPYNKVEEHIKRANREAAAQTVKTILAYGYTLEPPTSELGESTKIQSGSKLENHLAAH GLLKATDKSLTETNMKKTRTYRAQLTYAVTAGKWYFECEVLTPGYMKVGWAKESAVPSEE IGMDGSSYAFDGLFGRKWNQGAEFYGKQWKTGDVVGCMLDLSDRTITFSLNGELMMDSLG QEIAFRNIEVSKGYVPAFTVGAFQQMRLNFGQDVNTLKYFTFCGLQEGYEPFCVNMTRIM SLWYTRDQAHFTTVTNSDPSIAVSRIPGGANVAPCLKVTSKTFGTLEDVKLEYLRLSLPV KCKDEFIPSRDKVSHQATLDRHMNLENLRRRELDIEEEQDGGTDPGTENYSDANMSDASI ERGSKLVADTLRHLVGTNRRHVSSHNHKHHDPTNSDGRPPSPILKHSKKCTTILENNTDT VSKDSPGSQGSHPGSQGSKGSHAAATSSSGTRSTKHSNDDDSSIAGMSHSFTEDTIDSRR SKTKSKSLSRGHSLEESSNDGGPGRLKTAASESMLAGDTGSLAIPPDGRKVSSKLSLLGD KLGDAARMLAERSSVKKPKTPFSMFKKKSSRDPSPNDTRGRARSTEYGGSLDRHKPGMRS AGGRSPNRNTTLPITRLSDEADGNGSTNGPLMNLDAPRAIIPYEFQDAMGRGGGRGFTQD GSDPDLTEADLMEMNAWAEHVDEYYYSVRIFPGQDPGQVYVGWMTPGFHSIQKSFDTKKT RHAVVSLLDQDFRIKSSVGRKNCYMVCAGDLQQRYGNSSSSTDVSSKRTSPGLLIGCTID VATGVLAFSVNGKEVANKFQVEPGAKLFPAVICEPTIKEMLQFELGSTKNALPLSAAVFR GPKSVVPTCPPRLDVQSLVPSSWARVPHNATYVQSLKLSDIRGWSMLSDKTISMQSVFIP EEDCSMDILDLIEHEHLLNFHATTLELYQAVCSHGNHNVASTLTHHVDILQLMYCIQSEY LSGPLRAGFHNMLIAMHLDSHTRARHGTEKEYIIPLTDQVQSLSLYRQLSPTSDTYKIKH TIPNMDASVSIRPKLCLNKKDIETRNQTRNKAGTSPYFPMDRLKMFMMQALTDGVEKGAA HIRDPIGGSNANLFVPMLKTLDNLLVMGLLTDDDLHQLLLLIDPETFDENGHLGSKRNGL LHMKLAEPVKLEVCRILQHLCDIQLRHRVEAIIAFSRDFVGQCQNDQLRRYNDIKQANLP SSVTARKTREFRCPPSEQMRNLLAFKTAAEELIHNCPCISEIRDVMWNFHSNLLKHCSMP TAIDSEGGTEAPSEAQLQEQTTGLTQRLLSLVWQAPETPADQPADSSQAKIDSIQKLIQK TMVMWAEEDFITSPDLVREMFSLLHRQYNGIGELLEALQKAYVISSSSVVDINSLLKALG NIRSLLLVQAGPDEEELMMNSLKDLMDNKVFFQHPDLMRALCVHETVMQLMVNTLNKAQQ QQQSTTSSELASTSQRRHSTVQPTSGLDNNFAESGKDAAAEMVVMCCRFLCYFCRTSGQN QRAMFEHLSYLLDNSSMLLARPSLRGSCPLDVAYSSLMDNNELSLALREAHLEKIAMYLS RCGLQSNSELLEKGYPEIGWDPVEGERYLDFFRFCVWVNGETVEENANLVVKLLIRRPEC LGPALRGEGGGLLKAMKDGIRMSEQIAAARDGTSCMFLSAMNDDDDSDGKYLFQSKFDFS TLPPEDDEDYVDMGGAILNFYSSLVDLLGRCAPDAESIKAGRSDALRARSILRSLVSMED LEGVLGLRFILPVGGEADGALPPGLLPPHKASVVMFLERVYGIEDQGTFFRLLEDCILSD LRAATTLDMAASSESDMTLALNRYLCGSVLPLLTKHSHFFMDADHMSSLLESTLNTVYRL SKCNSLTKNQRDMVSDFLVAFTNQLRPPMMAKLLRKMAVDVPALNENTVVPLRVLTAYYE RCGRYYSHGGWGSFGAASDEEKRLTMMLFSGIFDSLSQRAYDPELFSKALPCLSAIGCAL SPDYSLSSHDDTWYQQALAESEQTYNPNPVDTARVHLNQNLESACMKFAEHFHDTWALKK MDEGWTYGSAFDDDRKSHPMLKPYHALADREKNKYQYPVRDSIKSIVAWGWSLEQDQARL TANRESMKRRMSKDMFDHGYSPRPFDLRNMTLTRELQALSEQLSENSHDLWARSKKKELE EIGGGVHPQLVPYDILTEKEKKRDREHSQELLKFLQFLGFRLHSSNDLDLDAKGRKKSSA SRPTKDSETDQGVGGSAMEKRFAYSLLEKLLMYFDKASTSMTQTRNISRFSRRGSFTTAT KDVKFFGKVVLPFVEKYFRAHREYFAGGPNTPPTGSVASVKEKEMTASLFSKLTSTLRSK LNAFGHDVNISVRCLQVLIKAVDARTVVKNSPEIIRSSLLPFFNNTADDLANLVENLQNG RFSHVKGTITRGATSLSYVHMVLLPVLSSLFDHLGRHKFGPDLIVQDVQLACYRILNSLY LLGTSGNNFMHRETVTSELSRHRPALGECLSSFAGCFPVAFLEPKMNKYNKYSILFGLEG KISEHSLEAQEVMDLLQETLPPLEKILEEVDALAESGGKYMEAPHVIEVTLPMLCSYLPY WLQNAPAIQGNNPVSSVTVELMNRVLGNVLHLISNNIGAEDAPWMNTIASRVQPIISSSH PDMISDHFLPIAKKIRDNAMLVEQKEKQLYLSKLHQTQNDEDSDMEANVQLAFSILVRDI YAFYPLLIKYVDLHRSTWLKNPTTAAEELFTLIADIFLLWSKSIFYKREEQNFVLSNEID NMSLIMPSQTKPAVVQMDPSLESKKPTGRRREKKRLEPHNSLNVACLKRLLPIGLSFFSG REQELLQTVKQKLIDDPEADLEDFLGKILEEVEGPIDDKIKWQKVLYHKIGGGSGSNKDQ GRVIDRIISMAKVMHGLHTVEHPLAHHKNVWRKVVSTQRKRAVMACFRMIPLHNLPKHRC INLFLKCYRSQWLVTEEYEKKVLIDDLTRSDVKEEEAVEKKEEEVERPDPLKQLITCLSR AATKEQQSSMPEDILYISYAQIMSQSCSGADDDDDDEGGEEDGPGSSFQLHLDILKEQEM EKQQLLSEQARLSERGAAEMVLLYISASRGCVGPMVSETIETGISLLRGGNIDVQKRMLR HLKDKKDVGCFTSLAGLMQQCSVLDLDAFERTNKAEGLGMSSEATPGEKNLHDADFICKL FRFLQLLCEGHNLEFQNYLRTQAGNNTTVNIVISTVDYLLRLQESIMDFYWHYSGKDTID TAGKENFCRAINVSKQVFATLTEYVQGPCSQNQLTLAHSRLWDAVGGFLYIFAHMQEKLS RDSEQLELLREFMKLQKEMMIMLLSMLEGNVMNGPIGKQMVDTLVESSGNVEMILKFFDI FLKMKDLTTSDAFLEFDTNKDGYISAKEFRRAMDSQKMYSREEIEYIMMCVDANQDGKVD FNEFTDRFHNPAKDIGFTMAVLLTNLSEHMPNDPRLERFLEKASCVLDYFQPYLGRIEIL GGAGRIERVYFEIKQSHIDQWEKPQIKESKRSFLHSVVNEGGDKEKLESFVNFCEDTIFE MQHATSISAEEQRMAALRSGAVPDTRGGVLQPVKMGYNYVKDNIGLFLSLFTMSNVRQSY RAFHKMTYFQLFVALMKLNFRIAFTLLSVLFHIVWTLGQFVLNMMLGEPDPSRDGELPVP AGPLALPGPATPGSIHPATPIPVPGLDPYPEHKEEGKIITLSDTRQSATGQSSLDSDKAT ADEPHIADTSSTQREPMRTPELSRQMSSINNIGQPGVGNDQEEEATYDTKSFDYRKYVLR TLTNIGSLFARNFYNFKYLALLLAFLINFLLLFYKVSRLTVEVVGGEEETADAVADLAMN LTEALTGQEEEVEEEVEELVSMSESSYYLEHVLRCLAVCHSLAAFSMLVAYYCLKVPLVI FKREKEIARKLEFDGLWIAEQPGEDDLKSHWDKLVLSTQSFPDSYWDKFVKKKVRNRYAE QYEYEAISNLLGMEKSDAITIDKEEKTGLFKFLYSVDWQYQIWKWGVIFTDNSFLYIAWY FTWSCLGNLNHFFFAAHLLDVAVSFNTLRTILQSVTHNGKQLILTVMLLSIIVYIYTVIA FNFFRKFYVKDEDGSVDYKCHDMLTCFVYHLHTGVRAGGGIGDEIEPADGDAYEIWRILF DITFFFFVIVILLAIIQGLIIDAFGELRDQLEQVKEDMESKCFICGIGKEYFDKIPHGFE THVANEHNFANYMFFLMHLINKPDTEYTGQETYVWALYQQRCWDFFPVGDCFRKQYEDEI GGAQKS NT seq 15861 nt NT seq  +upstreamnt  +downstreamnt atggcggagcccggtgatgcagtatcatctgaacaggatgatatttcgtttctccgaaca aatgacatggtatgtttgagctgcgtcactgccaccacaagggacagtccaagtgagaga gtgaaccttgctgcagagggctttggaaaccgcatgtgctttctagagaatgtctccagc aaggacattccgccagacatttccatgtgtgtgtttgtgttggaacaagctctgtctgtt agggcgttacaagaaatggtcacctcatcgtctcaagactcttctgcagcgcagtcaggg catagaacccttctatatggccatgcggttctgttgagacatcttccaagcaacatgtac ctgtcatgtctgtccaccagttcctccaatgacaaactggcctttgatgtcggcctcaac gaatcttcacaaggagagtcttgctggtggacaatccacccggccagcaagcagaggtca gagggtgagaaggtcagggtcggtgatgacctcatactggtcagtgtgtccagtgagaga tacctgcacatcggcagcagttctgaagtgatagcctccttccagcagacactgtggacg gttgtacccatgagttcaggcgtcatcagagtcaaatcaatggggtttgtgtttggtggc gatgtgctccgactgttccatggtcatatggatgaatgcctaaccattcctgaggcaggc agtgacagtgaattcaactgtgtgatgtatgagacaggggctgtgtgcagccatgcccga tcactgtggagattagagttcatcaaaacgaagtgggcaggtggtttcatgggctggggg cagcaggtgcgtatccgtcatgtgacctcgggtcgttaccttggcatcactcacgaccac aacgtggttaccgtgcacaggggcaaggcagacgaggataccacctccttctatttgcga caaaccaaggatgacaagaagcttgctgaaggtcatgaggacgagggtatgggcaagtgt gacctcaagtatggggactctgtcgtgttcatccagcactgtgccacaggcctatggctc tcctaccagacctttgagaccaagaaacggggcgtagggcgcgtagaggagaaaaaagca gtgatgctggtggaaggtcacatggacgatggtatcacactgtccagggctcaggaggaa gaatctaggtcggccagggtcatacgcaagtgtcagtcgctcttcaataggttcaacaaa gccctggatttactgaggagtgagggccgaacatgtattgcctggtcccgtatacggctg tcagaggttgtcaagtgccttactgatctaattgactattttcaacaacctgctgtcgat gaagaacatgaggagaagcagaacaagctgcgagccttgaggaaccgccaggacctgttc caggaggagggcatgatcgcgctgatccttgagaccattgacaagttcggtcagtacaaa ggcaagaggcagtttgcacactacgcaggcgaggaggcagccaacaaatgggacgatatc tccagctacctctaccttctcttagctgcaatgatccggggtaaccgtgccaactgtgcc cagtttgctcagtcctacaggctcgactggcttgtacacaggctcgagagtcagatgtca tccaaaggtgttctggacgttctacactgtgttctcatcgactcaccagaggcactgaac atgatcaaggaaaaacatatcataaccatcatatcactgattgacaagcatggaagagac cctaaggtgcttaacgttctcaagtccctgtgtgtgggtaacaacgtggcggtgcgcacc aaccaaaacctgatctgtgagaacctgctgcctggtcgagatctcctcctgcagaccaaa ctggtagatcacgtgtttagtatgaaacccaatatctacgttggtctgtgtgagggctct tcgatgtacaggcgctggtatttcgaggttgttgtcgaccagtttgaggctgggtctcac ctgccgcccctgttgcgtattggctgggccagcagctccgggtttgtgccgtaccctggc gggggacagggctggggttgcaatgcagcaggggatgatctgtactcattcgctttcgat ggcaactgcttttggacaggagcaaagcgtaagcaggtgcgagacctcagtttgatattc aggaagggtgacgtggtgggctgcctactggatctgacaggccccaagatatccttcacc atcaatggggcgcctgtcatgggcctgttcaaggatttcaatctggacgggttgttcttt cctgtcatctccatgacggcatgtgtcagttgtcgtttcgtgcttgggagtgaacatggc aagctgaaatacgggcctccggagggccactcgccagccattgagtccctgctacccaaa cagaaactgaaaattgagccctgcttctactttggggacgttcagaagaacattatcagt ggccccactgaggtccttgattatgccccttttgtacctcagccagttgatacaggcaat gttcagctgccagtgtatgtagaatgtgtgcgagacaaattagccgagaaccttcatgag gtgtgggccatgaacaagatagaccagggttggtcctggggggagatacgtgaagacaca cgcaaaaagaatcccagtcttaccagctttgagaagctgcccatgtccgagaagaaatat gttgtcactgtggcttttgaaacactcagaactctcctggcccttggataccatgtctcc atggaaatgaaggattccaagacaaacagaatgaagactgtcaagctgagttcagatttc ctacaaagcaacggctacaagccaatgcccctggacttgtcaggcactgagctggatgag aaaatgtgtgaccttgttgaactcctggcggagaacacacacaatgtctgggccaaggat cgcatcaagaatggatggacatatgggctgtgtgaggatctagcaactaagagaagcccc catttagtgccttacaacaaagttgaggaacatatcaaacgagcaaacagggaggctgca gcccagacggtaaagacaatacttgcctatgggtacacattagaacctccgaccagtgag cttggagagtcaacaaaaatccagtcaggaagcaaactagaaaaccatttggctgcccat ggtttattgaaagctaccgacaagtcattgacagaaaccaatatgaagaaaaccaggact taccgtgctcagctgacgtatgctgtaacagctgggaaatggtattttgagtgtgaggtg ctcactcccggctacatgaaggtgggctgggccaaggagtcagcagtcccctcagaggag atagggatggatggcagctcgtacgcatttgatggactctttggtcgcaagtggaaccag ggagctgaattttacgggaaacagtggaagacaggagacgttgttggttgcatgctggat ctgtctgaccgcaccattacattttctctgaacggagagctgatgatggactcgctgggg caggagattgcgttccgtaatattgaggtcagcaagggctacgtcccagcgttcactgtg ggagccttccagcagatgaggctcaactttgggcaggatgtcaacacactcaagtacttc accttctgtggactgcaggagggatatgaacctttctgtgtaaacatgacccgcatcatg tcgctgtggtatacaagggatcaggctcacttcaccacggtgaccaacagtgacccctcc attgcagtatcacgaatccctggaggagcgaacgtggccccatgtctgaaggtgacctcc aagactttcgggacgctagaggacgtgaaactcgagtacctgagactgagcctgccagtc aagtgcaaggatgagttcatacccagtcgtgacaaggtgagccaccaggctacactggac cgacacatgaacctggagaacctgcggcggcgtgagctggacatagaggaggaacaagat ggaggcactgacccaggcacggagaattacagtgacgccaatatgagtgatgcctccatc gagagaggcagcaaacttgtggcagacaccttgcgtcatcttgtcggcacaaaccgtcgg catgtctccagccataaccataaacaccatgatcccactaactcagatggccgcccccct tctcccatcctcaaacactccaagaagtgcacgaccatccttgagaataacacagacacg gtgtccaaggactcgcctggtagccaggggtcacatcctggaagccaggggtcaaagggg tcgcatgcggctgctacttcctcttctggcactcgctccactaagcacagcaatgacgat gactcatctatcgcaggaatgagtcacagtttcacggaagacacaatagatagtcgaaga tcgaagaccaagtcaaaatctttgagtcgaggtcactctcttgaggagagctcgaatgac ggtggtcccgggcgtttgaagacggcagccagtgagtcgatgctggcaggtgacacagga tcacttgcaatccctcccgacggaagaaaagtctcttccaagttgtcacttcttggagac aaactgggtgacgctgctaggatgctggccgaaaggagctcagtgaagaagccaaagact cctttctcaatgttcaagaagaaatcatccagagacccctcacccaacgacactaggggt cgtgctcgaagtacagagtatggaggcagtcttgaccgtcacaagcccggaatgcggtcc gcagggggccgctctcccaatcggaacaccaccttgcccatcaccaggctcagcgacgag gccgatgggaacgggtcaacaaacgggcccttgatgaacttggacgctcccagggccatc ataccgtatgagttccaagatgccatgggtagaggaggtggtagaggcttcacccaggac gggtctgatcctgacctgactgaggccgacctcatggagatgaatgcctgggcggaacat gtggatgagtactactactcggtgagaattttcccgggtcaggatccaggacaggtgtat gtgggatggatgacgcccggcttccacagcattcagaaatcatttgacaccaagaagact aggcatgctgttgtgtcacttcttgatcaggacttcagaatcaaatcaagtgttggccgc aagaactgctacatggtttgtgcaggagatctacaacagcgatacggtaacagcagcagc agtacggacgtgtccagcaagcgaacctcaccgggcctcctgattggctgtaccattgac gtggcaacaggggtgcttgcattctccgtcaacgggaaggaggttgccaacaagttccag gttgagccgggagccaagctgttcccagctgtgatctgcgagccaacgataaaagagatg ttgcagtttgaactagggtctaccaagaatgccttgccgctgtcagctgcagtgttccgt ggcccgaagagtgtggttcccacttgcccgccccgtctggacgttcaatcactggttccc agtagctgggctcgagttccccacaacgccacctatgttcagtcgctgaaactgtcagac attcgtggctggagcatgctgtctgataaaacaatctcgatgcagtcagtgttcatccca gaagaggactgctccatggatatactggacctcatagaacatgaacacctgctcaatttc cacgcaacgaccctggaactgtaccaggcggtgtgttcccatggcaaccacaacgtggcc agcaccctgacacaccacgtggacatactgcagctgatgtactgcatccagagcgagtac ctgtctggaccccttcgcgcaggctttcataacatgctgattgccatgcacctggactcc cacacaagggctagacacggcacagagaaggagtacatcatcccgctgacggaccaggtg cagtccctgagcctgtacagacagctcagtcccaccagcgacacatacaagatcaagcac accatacccaacatggacgccagcgtgtccatcaggcccaagctgtgtctcaacaagaaa gacattgaaaccagaaaccagacaaggaacaaagctgggacgtccccatatttcccaatg gaccgtctgaagatgtttatgatgcaggcactcacagatggggtggagaaaggtgctgcc cacatacgggaccctatagggggcagcaacgccaatctgtttgtgccaatgttgaagacg ctggacaatctcctggtgatgggtctgctcactgatgatgacttgcaccagctactgctc ctcattgacccagaaaccttcgatgaaaacggccacctcggctcaaagaggaatggactg ctgcacatgaaacttgcagaacctgtcaaactagaggtgtgccgaatcctgcagcacctt tgtgacatccagctgagacacagggtggaggccatcatagccttctcacgagactttgtg ggccagtgtcagaatgatcagctacgtagatacaacgatattaagcaggccaatctgcca tcatctgtgacagccagaaagacacgtgagtttcgttgtcccccgagtgagcagatgagg aatctcctcgcgttcaagacagccgcagaggagctgattcacaactgcccgtgtatcagc gaaattcgagacgtaatgtggaacttccactccaacttgctcaagcactgttccatgccc acagccatcgattctgaaggagggacagaggctcccagtgaagcccagctgcaggagcag acaacagggctgacccagcgacttctctcccttgtctggcaggccccagaaaccccagct gatcagcctgctgacagctcccaggccaagatagattcaatacagaagcttatacagaaa acaatggtgatgtgggcagaggaggactttattacctcccctgaccttgtcagagaaatg tttagtctgctgcatcgacagtacaatggcattggagagttactggaagccctgcagaag gcgtacgtgatcagctccagtagtgtggtggacatcaacagcctgctgaaggccctgggc aacattcgctctctgctcctggtacaggctggaccggatgaggaggagctgatgatgaat agtctcaaggacctgatggacaacaaggtgttcttccagcatccagacctgatgcgggcc ctgtgcgtgcatgagacagtcatgcagctgatggtgaacacactaaacaaggcgcagcag caacaacagtccaccacgagcagcgagctcgcctccaccagtcaaaggagacactccact gtgcagcccacctccggcctcgacaacaactttgcagagtcaggcaaggatgctgctgct gagatggtggtgatgtgctgtcgattcctctgctatttctgtcgcaccagcggacagaac cagcgtgccatgtttgagcacctcagctacctgcttgacaacagcagcatgctattagct cgcccatccctgcgtggctcatgccccctggacgtggcctacagttccctgatggacaac aatgagctgtcgctggctctgcgagaggcccacttagagaagattgccatgtacctgtca cgctgtgggctgcagtctaactcagagctgctcgagaaggggtatccagagatcggctgg gatcccgtggagggggagagatacctggatttcttcagattctgtgtctgggtcaatgga gagactgtagaggagaatgccaacctggtggtgaagctgctgatcagacgtcccgagtgt ctggggccggccctcaggggggagggtgggggtctcctaaaggcaatgaaagacggcatc cgcatgtcggagcagatagctgcagctcgtgacggcacctcttgcatgttcctctccgcg atgaatgatgatgatgactctgatgggaaatatctcttccagagcaagtttgatttctcc accctaccaccggaggatgatgaagactatgtggacatggggggtgcaatccttaacttc tacagcagccttgtcgacctgctaggtcgctgtgctcctgacgcagagtctataaaggca ggccggagtgacgcactacgcgcgcgctccatattgcgttccctggtatccatggaggac ctggagggcgtgctggggctcagattcatactgccagtaggaggggaggctgatggtgcc cttcccccaggcctgttgccgccccacaaggcgtccgttgtgatgttcctggagcgcgtg tacgggatagaggatcaggggacgttcttcagactccttgaagactgtatcctgtctgac ctgcgagctgcaaccacccttgatatggcggcctcctctgagagtgacatgactctggcc ctgaaccgctacctgtgtgggtcggtactgcccctgctcaccaagcacagccacttcttc atggacgcagatcacatgagctccctgctggagtccacactgaacacggtgtaccgcctc tccaagtgtaactccctcaccaagaaccagagggacatggtgtccgactttctggtcgcc ttcacaaatcaactgaggccccccatgatggccaagctcctgagaaagatggcggtggat gttcctgctcttaatgagaacactgtggtacctctaagggtgctcacagcatactacgag cgttgtggccgttactatagccacggtggttggggctcgtttggggcagccagcgatgag gagaagaggctcactatgatgctgttttctggaatatttgactccttgtctcaaagggcg tacgaccctgagttgttctcgaaggcattgccatgcctctctgctattggatgcgccctt tcaccggactactcactgagcagccatgatgacacctggtaccagcaggcactggctgag tctgaacaaacttataaccccaaccctgttgatacagcaagggttcatctcaaccagaac ttggagtctgcctgtatgaagtttgcagaacacttccatgacacatgggcactgaagaag atggatgaaggatggacgtatggcagtgcctttgatgatgacaggaagtcccatcccatg ttgaagccataccacgcactggcagacagggagaagaacaagtaccagtatcctgtgcgt gactccatcaagtcgatcgtggcgtggggctggagtctggagcaggaccaggcgcgactc acggccaacagggagtccatgaaacgcaggatgtcaaaggatatgtttgaccatgggtac agtccacgaccgtttgaccttcgaaacatgaccttgacccgtgaactgcaggcgttgtca gaacaactgtctgagaactcacatgacctgtgggctcgtagcaagaagaaggagctggaa gaaataggaggtggtgtgcacccccagcttgtcccctatgacatcctgacagagaaggag aagaagagggaccgagagcactcccaggagctcctcaagttcctgcagttcctcggcttc cgtctacacagcagcaatgacctggatctggatgcgaagggacgcaagaagtcgtctgct tccagaccaacgaaggattctgagacggaccagggcgttggtgggtcggccatggagaaa cggtttgcatacagcctcctagagaagttgctcatgtactttgataaggcctctaccagc atgactcagaccagaaacatctccaggttcagtaggcgcggaagtttcaccaccgccact aaggatgtgaagttctttggcaaggttgtgttgccgtttgttgagaagtatttccgtgcc catcgcgagtactttgctgggggacccaacaccccacccacaggctccgtggcctcagtc aaggaaaaggagatgactgccagcttgttttccaaattgacttccactctgcggtcaaag ttgaacgcctttggccatgatgtgaacatctcagtgcgatgtcttcaggtgctgataaag gctgttgatgccaggactgtagtcaaaaacagcccagagatcatccgttcgtcccttctg ccgttcttcaacaacacagcagacgacctcgcgaaccttgtggaaaaccttcaaaatggc cgcttcagtcacgtgaagggaacgatcacccgcggggctacaagccttagttacgtgcac atggtcctgcttcctgtgctctcgtctttgtttgatcatctcggtagacacaagtttggc ccggatttgatagtgcaagacgtacagctagcctgttaccggatcctgaactccctctac ctactgggaaccagcggaaacaacttcatgcacagggaaacagttacatcagaattgtca agacaccgaccggccctgggtgagtgcctgagctccttcgcaggctgtttcccagtggcc ttcctcgaacccaagatgaacaagtacaacaagtactccattctctttggactcgagggg aaaatatcggagcactcgctggaagcacaagaggtgatggacctgctgcaggagacgctg cctcccctggagaagatcctggaggaagtggatgcccttgcagagtccggggggaagtac atggaggccccgcacgtcatagaggtcaccctgcccatgttgtgtagctacctgccctac tggctgcagaacgcccccgctatacagggcaacaatccagtgtccagtgtgactgttgag ctaatgaaccgagtccttggcaacgttcttcacctgatcagcaacaacattggtgctgaa gatgccccttggatgaacaccattgcatctcgagtccagccaatcattagcagctctcac ccagacatgatctctgatcacttcctgcctatcgctaagaagatccgagacaatgcgatg cttgttgagcaaaaggagaaacagctgtacctgagcaagcttcaccagacacagaatgat gaggactcggatatggaggccaatgttcagctggcatttagtatcctggtgcgtgacatc tacgccttctacccgctgttgatcaagtatgtggacctgcatcgctccacgtggctcaag aaccccaccacagcagccgaggagctgttcactctcatagctgacatctttctgctctgg tccaagtccattttttacaaacgagaggagcagaactttgtgctgtccaatgagattgac aacatgtctctgatcatgcccagtcagaccaagcctgctgttgtgcagatggacccgagt ctggagtcaaagaaacccaccgggagaaggcgtgaaaaaaagcgtttggagcctcataac agtctgaacgtggcctgtctcaaacgtcttctgcccattggtctgagcttctttagcggc cgagagcaggaactgctgcagacggtcaaacagaaactcattgatgacccagaggcggat cttgaagactttctggggaagattttggaggaagtagaagggcctattgatgacaagatc aagtggcagaaggtcttataccataagataggtggagggtcagggtcaaacaaagaccag gggcgtgtcattgaccgcatcatctccatggcaaaagtcatgcatggcctccatacagtt gaacacccattggcccaccacaagaatgtctggaggaaggttgtgtccactcagagaaag agagctgtcatggcctgcttcaggatgataccattgcataacctgccaaagcaccgctgc atcaacctgttcctgaagtgttaccggtcccagtggctcgtcaccgaggagtatgaaaag aaggtgctcattgacgaccttactaggagtgatgtgaaagaggaggaggctgtagagaag aaggaggaggaggtggagcgacccgaccccctcaagcagctcatcacctgcctgtcccgg gccgccacaaaggagcagcagagctccatgcctgaggacatactctacatctcatatgca cagatcatgagtcagagctgcagtggcgctgacgatgatgatgatgatgaaggtggggag gaggatggtcctggctcttctttccaacttcacttggacattctcaaggagcaggaaatg gagaagcagcagctactgtcagagcaggcccggctgtctgagcgcggggcagcagagatg gtgctgctctacatcagtgccagcaggggttgtgttgggccaatggtatctgaaaccatt gagactggaatttccttgctaagaggtggaaatattgatgtgcaaaagaggatgctgcga cacttgaaggacaagaaggatgtagggtgcttcacctccctggcaggcctcatgcagcaa tgcagcgtgttggatcttgatgcatttgagagaaccaacaaggcagaaggtctaggcatg agctctgaggcaacaccaggggagaagaatctccatgacgcagacttcatctgcaagctc ttccgcttcctgcagttactttgtgaaggacataatctagaattccagaactatttgcgc acacaggctggtaacaacacaacagtgaacatcgtcatcagcacagtagactacctactg agactgcaggagtccatcatggatttctactggcactactctggcaaggacaccattgac actgctggcaaggagaacttctgtcgggcaatcaacgtctccaagcaggtgtttgcaaca cttacagagtatgtacagggcccgtgttcccagaaccagcttactctggctcacagtcga ctgtgggacgcagttgggggcttcctttacatctttgcccatatgcaggagaaattgtcc agggactcagagcagctggagttgctgagagagttcatgaagctacagaaggagatgatg atcatgctgctctccatgcttgaaggcaatgtgatgaatggaccgataggcaaacagatg gtggacactctggtagagtcttctggcaatgtagagatgatcctgaagttctttgacata ttcttgaaaatgaaggacttgacaacatcggatgcattcttggagtttgatacaaacaaa gatggctatatatcggccaaggaattccgccgtgccatggattcacagaagatgtattca cgtgaggagatagagtacatcatgatgtgtgtggacgccaaccaggacggcaaggtggac ttcaacgagttcacagaccgcttccacaacccggccaaggacatcggcttcaccatggct gtactgctaaccaacctctctgagcacatgcccaatgatcccaggttggagcgtttcctg gagaaggccagctgcgtattggactacttccagccttacctgggtaggattgagatcctg ggtggagcaggacgcattgagagggtctactttgagattaaacagtcacatatagaccag tgggagaaaccacaaattaaggagtcaaagcgttcgttcttgcacagtgtcgtcaatgag gggggagacaaggaaaaactggagagctttgtgaacttctgtgaggataccatttttgag atgcagcatgcgaccagtatcagtgcagaggaacagaggatggctgcactacgtagtggc gcagttcccgacacaagaggaggtgttctgcagccagtgaagatggggtataattatgtg aaagacaacattggattattcctgtctttgtttacaatgtccaatgtgagacagtcgtac cgggcgtttcacaagatgacctactttcaactgtttgtggcattgatgaaattgaatttt cgcatcgctttcaccttgctgtctgttctcttccatatagtgtggacactaggccagttt gtactgaacatgatgctgggagagcctgacccatcccgtgatggggagttgcctgtacct gctgggcccctggccctccctggccccgcaactccaggctccatccacccggccacgccc attcctgtcccaggcctggatccgtaccctgaacacaaggaggaaggcaaaatcataact ctgtctgacacaagacaatctgcgacagggcagagtagcctagactctgacaaggcaact gctgatgagccacacattgctgatacctcgtcaacacagagagagcccatgagaacacct gaactgtccagacagatgagttccatcaacaacattggacagccaggagtgggcaatgac caggaggaggaagccacctatgataccaagagctttgactacaggaaatacgtactgagg acattaacaaacattgggagcttgtttgcccgcaacttttacaactttaagtacctggcc ctcctgcttgccttcctcatcaacttcctgctgctcttctacaaggtgtcgcgcctgacc gttgaagttgtcggaggggaagaggaaaccgcagatgctgtagcggacttggccatgaac ctgacagaggcgcttactggtcaggaggaggaagtggaagaggaggtggaggaactggtc tccatgtctgagagtagctactacctggaacacgtgctgcgctgcctggccgtctgccac tcactggcagcgttctccatgctggttgcgtactactgtctgaaggttccgctcgtgata ttcaagcgggagaaagagattgcaaggaagcttgagtttgacggactctggattgccgag caacctggggaggatgatctcaagtcgcactgggacaagctcgtactcagcactcagtcc ttccctgacagctactgggacaagtttgtcaagaagaaggtgcgtaaccgttatgcagag cagtacgagtatgaggccatcagtaacctgctgggcatggagaagagtgatgccatcacc atagacaaggaggagaaaacggggctgtttaagttcctctacagtgtggactggcaatat cagatatggaaatggggtgttattttcactgataattctttcctgtacattgcctggtac ttcacctggtcctgcctgggaaatctcaaccatttcttctttgcggcccacttgctggat gtggctgtcagctttaacacactgcggactatcctccagtctgtgacacacaatggaaaa cagctgatactgactgtgatgctgctgagtattatagtgtacatctacacggtgatagca ttcaacttcttcaggaagttctacgtgaaggatgaggatggctccgtagactataaatgc cacgacatgctcacttgttttgtgtatcacctgcacacgggtgtgcgtgccggaggtggt attggagatgagatagagccggctgacggggacgcctacgagatctggaggatcctcttt gacatcacattcttcttctttgtcatcgtcatcctcctggccatcattcagggtttgatc attgacgccttcggagaactgagagaccagctggaacaggtcaaagaagacatggagtcc aagtgcttcatatgtggcataggcaaggagtactttgataaaataccacacggctttgag acccatgtggccaatgaacacaactttgctaactacatgtttttcttgatgcacctgatc aataagccggacactgagtacacaggccaggagacgtacgtgtgggcgctgtaccagcag aggtgctgggacttcttcccagtgggagactgcttcaggaaacagtacgaggatgagata ggaggggcgcagaagagctag

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