Dryobates pubescens (Downy woodpecker): 104299335 Help Entry 104299335         CDS       T08526                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism dpub  Dryobates pubescens (Downy woodpecker) Brite KEGG Orthology (KO) [BR:dpub00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:dpub04121]     104299335 (UBR4) Enzymes [BR:dpub01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      104299335 (UBR4) Ubiquitin system [BR:dpub04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     104299335 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR ARM_LRRK2 Motif Other DBs NCBI-GeneID:  104299335 NCBI-ProteinID:  XP_009897795 LinkDB All DBs Position Unknown AA seq 5095 aa AA seqDB search MHARLESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACKVLIEFSLLR LENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQK ELASPVSPELRQKEVQMNFLNQLTSVFNPRVSSSPSIMSEAQVEGESEDQASTDQSSAAK TKSIFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATA VRNGFHSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGS TQQVRTGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCL LNSLFLILNLSPTALADKGKEKDPLAALRVRDIIARTKEGVGSPKLGPGKGHQGFGVLSV VLANHAIKLLSSLFQDLQVEALHKGWESDGPPAVLDIMAQSTSIQRIQRLIDSVPLTNLL LTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQW FEETISPSKEKVAPPPPPPPPPLESSPRVKSPNKQSTGENGNILASRKDPELFLSLASNI LNFLTSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFN HSLVTSDLQSPALQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKASAQGDP DVPECLKVWERFVGTLKQNALQGTLPSDTEDLNVEHLQLLLLICHNFSERGRRSVLLLCI QTIVELTGSMETQQAAVPLVVARLLLVFDYLLHQYAKAPVYLFEQVQYNLLTPPIGWVSG SQDSSRRTSVPLYHGFKEVEENWTKHCSSDAAPQPRFYCILSPEASEDDLNRLDSTVCEV LFSRTMKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPP SKNYMNQLATNTPEMSECDILHTLRWSSRLRITSYVTWIKDHLIKQGMKADHAASLTELA SSKCSSVKYDVEIAEEYFARQISSFCGVDCTTILQLHEVPSLQSIYTLDAAISKIQVSLD EHFSKLAAETDPHKSSEITKNLLPATLQLIDTYATFTRSYLLRSLSEEGSPENKPCEEKL RGYAAVLAIGSSRCKSNALGPTLVQNLPSAVQTLCESWNNIHTNEFPNIGSWRNAFANDT IPAESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNPPQVIHSLL PLLLETSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDES ILEECLQHLEKQLESSQARKAMEEFFSESGELVQIMMATANESLSAKFCNRVLKFFTKLF QLTEKSPNPSLLRLCGSLAQLACVEPARLQAWLTRMTMAPPKDSDQLEVVQENRQLLQLL TTYIVRENSQVGEGVCTVLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQ LHGAAVDWLGRCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALGQSSG QGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQH WYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSG MSSTMKESAFQSEPRVPESVIRHASTSPAEKAKVTISEGKGPDEEKPKKSSLCRNVEGCR EELQSQANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALNELHTLDKSVEMTD QLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSH EKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCH VLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPT FYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNH EDLKDSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRASLEVQRLFPINIKSSNG GSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVA IRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAA ITTRTSSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGF TIEVTNNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNMTRARWFDFPFTREEALQ ADKKLTIFIGASVDPAGVTMMDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQG NGTGDAESAAPAAASGTVLERLVVSSLEALESCFAVGPVNEKEKNKVAAQELATMLLSMP APSSVQQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVIT ARSIAIMRPNNLVHYTESKLPQLEAEGEEGQDAQKHTEGDGCTFITQLVNHFWKLHASKP KNAFLAPACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSC KQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQ EQSEVDHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVE LAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAAT DGSTPLSGRSSAYGDTAAEGHPAGPGSVSSSTGAISTTTGQQEGDGSEGEGEAEGDVHTS NRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVILMLTTDLDGDDEKDKGALDNLLSQ LIAELCMDKKDVSKKNERSPVNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAA ALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKG HAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPIFDHSWFYFLSEYLMIQQTPFVR RQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYD TLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCAL CGSKVLSVASSSGSSSTSSTSAPAASGSGQPTTQSKSSTKKSKKEEKEKEREGESLGSQE DQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLALHIYRNSNKSQQELLL DLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKKLKEYSQKAVEILRTQNHILTNHP NSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGS HTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVK IDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCR SINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADR VYHQLMGHRPQLENLLCKVNEAAPEKPQDESGSGGGISSTSASVNRYILQLAQEYCGDCK NSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTTVQPTFTASQYRALSVLGCGHTS STKCYGCASAVTEHCITLLRALATNSAIRHILVSQGLIRELFDYNLRRGAASMREEVRQL MCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDLASSLQYEMLLLTDSISKEDSCWEL RLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPLDALTTVKPY SNEIHAQAQLWLKRDPKASYEAWKKCLPARGIDASGKSLSKAEIHQLYLSEKYVWKWKQF LSRRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALTTIPSRKQQVLDLLTS YLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARGVLPYIGSLITKEIARLLALEEATL STDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQ DMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSIIYPEENEVTE FFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMEL LVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEED EEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKP EMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLT GDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLSFGELEKMQILVDRFKPYCNFDKYD EEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNLDAD IWKKFLSRPALPFILRLLRGLATQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLL EALREHPEVNKKIDAARKETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQME ELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGYSTVSHFNIVHY DCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTG QREPTYQLNVHDIKLLFLRFAMEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATS REEKNLQSFMEHPKEKWVESAYEVDGPHYYTVLALHISPPEKWKAMRVEVLKRLLVTSHA RVVSPGGASRLADKAVKDYATYRSGLLFWALVDLIYNMFKKVPTSNTEGGWSYSLAEFIR HNDMPIHEAADRALKTFQEEFMPVETFAEFLDVAGLLSEINDPDSFLKDLLNSIP NT seq 15288 nt NT seq  +upstreamnt  +downstreamnt atgcacgcccggctcgagtctgagatcctgcaccacgacaagcagtatgagcccttctac tcctcctttgttgcactttctacacattacatcactactgtgtgtggtctcatccccagg aaccagctgcagtcggtggcggcggcgtgcaaggtcctgatcgagttctcgctgctgcgc ctggagaaccccgatgaagcttgtgctgtgtcacagaaacatctcatcctgctgatcaag gggctgtgcacgggctgcagccgcctggaccgcaccgagatcatcaccttcacagccatg atgaagtcagccaagctgcctcagactgtcaaaaccctctctgatgtagaggatcagaag gagctggcctccccagtgagcccagagctgaggcagaaagaagtgcagatgaacttcctc aatcagctgacatcagtctttaaccctagagtctcatcatcaccatctatcatgtcagag gcacaggtggaaggagaaagtgaggatcaagcttccacagatcaaagctctgcagcaaag accaaaagcatattcattgctcagaatgtagccagcctgcaagaacttggtggctctgag aagctgctgagggtctgcctgaacctgccctacttcctgcgctacatcaaccgcttccag gacgcggtgtcggccaactccttcttcatcatgccagccacggtggctgatgccaccgcg gtgcgcaacgggtttcattcgctggtcatcgatgtgaccatggccctggatactctgtcc ctgcctgtgctggagcctctgacacccacacgtctccaggatgtcactgtgcttgctctc agctgtctctatgcaggtgtgagtgtggccacctgcatggccatcctgcacgtggggagc actcagcaggtacgaactggctccacaagttccaaagaagaagattatgaaaatgatgct gctactattgtacaaaaatgtcttgaaatctacgaaatgattggacaagccatcagcaat tcacgccgggcagggggtgagcattatcagaacttccagctgctgggggcttggtgtctg ctgaacagcctcttcctcatcttgaacctcagccccacggccttggctgataaggggaag gagaaggatcccttggccgcccttcgagtccgagacatcatcgctcgcaccaaggagggc gtcgggtctcccaagctggggcctgggaaagggcatcaaggctttggtgttctgtcagtg gtgctagccaaccacgctatcaaactgctgtcctccctctttcaagacctgcaagtggag gcgttgcacaagggctgggagagtgatggtccaccagcagtgctggatatcatggctcag agcacctccatccagaggattcagcgcctgatcgattctgtcccactcaccaacctgctg ctgactttgctgtctacatcctacaggaaggcttgtgtcttgcagcgccagaggaagggc tccatgagcagcgacgcgagtgcctccaccgactccaacacctactatgaggatgacttc agcagcactgaggaggacagcagccaagatgacgacagtgaaccaatccttgggcaatgg ttcgaagagacaatctctccaagcaaagaaaaagtggccccaccaccacctcctccacca ccccctttggagagctcccctagagtgaaaagccccaacaaacagagcactggagagaac ggcaacatcctggccagccgcaaagacccggagctgtttctgagcctggcttccaacatt ctgaacttcctcacttcctccatgctgaactccaggaacaacttcattcgcaactacctg agcgtctctctctcggagcagcacatggctacgctggccagcatcatcaaagaggtggat aaggatggcctgaagggtacatcagatgaggagtttgctgctgcgctctaccacttcaac cattccttggtgacctcagatcttcagtctcctgctttgcagaacacacttcttcagcag ctgggagttgctcctttctctgaaggtccctggcctctctacatccatccccagagtctg tcagtgctctcaagacttctcctgatttggcagcataaagccagtgcccagggggatcct gatgttccagaatgccttaaagtgtgggaaaggttcgtgggcacgctgaagcagaacgcc ctgcaggggactcttcccagcgacacagaggacctgaatgtggagcacctccagctgctg ctgctgatctgccacaacttctcagagaggggccgcaggtctgtgctgctgctctgcatc cagaccattgtggagctgacaggcagcatggagacgcagcaggccgccgtgccgctcgtc gtggcgcggctgctcctggtgttcgactacctgctccatcagtatgccaaggctcctgtg tacctctttgagcaggtgcaatataatttgctgactccccccattggctgggtgagtgga tcccaggacagcagcagacgaacatctgtccctctttatcatggctttaaggaggtggaa gaaaactggaccaaacactgctcctcagatgcagctccacagcccaggttctactgcatc ctgtctccagaagcttctgaggatgatctgaaccgcctggatagcacggtttgtgaggtc cttttctccaggactatgaagtatgatgagctgtacacagccctgacttcactgcttgca gctggctcacagtttgatacactcaggaggaaagagaacaaaaatgtcactgccctggaa gcctgtgcacttcagtactacttcttgatactgtggaggattctgggcattttgcctcct tccaaaaactacatgaatcagctggctaccaacacaccagagatgagtgaatgtgacatt ctgcacaccttgcgctggtcctctcgcctccgaatcacctcctacgtcacctggatcaag gatcacctcatcaagcagggcatgaaagctgaccatgctgcttccctcactgagctggcc tccagcaagtgcagctcggtgaagtacgacgtggagatagccgaggaatactttgctcgc cagatatcttctttctgtggtgttgactgcacaactatcctccagctgcacgaagttccc agtttacagtccatttacaccctcgatgctgccatctccaagatccaggtgtctctggat gagcacttttccaagctggctgcagaaactgacccacacaagtcttcagagatcaccaag aacctcctgcctgctactctgcagctcattgacacttatgctacatttaccaggtcttac ttgctgcggagcctctcagaggagggctcccctgagaacaagccctgcgaggagaagctg cggggctacgctgccgtcctggccatcgggtccagccgctgcaagtctaacgctctaggt ccaaccctcgttcagaacttgccgtcggctgtgcagacgctgtgcgaatcgtggaacaac atccacacaaatgagtttccaaacattggctcgtggcgcaacgcctttgccaacgacacc atccccgccgagagctacatcagcgccgttcaggctgcccacctcggtaccctctgcagc caaagcctacctcttgcagcttccctcaagcacaccctcctctctctggtcagactcact ggggatctcattgtgtggtccgacgatttgaacccaccgcaggtgatccactccctgttg cccctccttttggagaccagcacagagagtgtggcagaaataagcagcaactccctggag aggattttgggccctgcagagtctgacgaattcctggcacgtgtttatgagaagctgatc acaggctgctataacatcctggcccaccactcggatccgaacagtggcctggatgagtcc atcttggaggagtgcttgcagcacctggagaagcagctggagagcagccaggcccggaaa gccatggaggaattcttctcagaaagtggagagctggtccagatcatgatggcaacagcc aatgaaagcctgtcagccaagttctgcaacagggtgctcaagttcttcaccaagctcttc cagctgactgagaagagtcccaaccccagcctcctgcgcctttgtggctctctggctcag ctggcctgcgtggagcctgctcgcctccaggcctggttaaccaggatgaccatggccccc cccaaagattcagaccagctggaggtggtgcaggagaacaggcagctgctgcagctcctc accacctacatcgttagggagaacagccaagttggagaaggggtctgcacggtcctgctg agcaccctgatacccatggcaactgaaatgctggccaacggggatggcacaggctttcct gagctgatggtggtgatggcaacgttggccagtgcaggacaaggtgcaggacacctccag ctccatggtgctgctgttgactggctaggcagatgcaagaaatacctgtcccagaagaat gtggtggagaagatgaatgccaatgtgatgcaaggcaagcatgtgactatcctggagtgc acgtgccacattgtctcctacctggctgatgtcactaatgccctgggccagagcagtggg caaggaccaagccacctttctgtggatggggaggagcgagccatcgaggtggattcggac tgggtggaggagctggcagtggaggaggaggactctcaggctgaagattcggatgaagat tctctttgtaacaaactctgtaccttcaccatcacacagaaggagttcatgaatcagcac tggtatcactgccacacctgcaagatggtcgacggggttggcgtctgcacagtctgtgcg aaagtttgtcacaaggaccacgagatctcttatgccaaatatggatcattcttctgtgac tgtggagccaaggaagatggcagttgcctggctttggtgaagagaactcccagcagtggt atgagctctaccatgaaagaatctgccttccagagcgagcccagggtgcctgagagtgtc attaggcatgcaagcacctctcctgcagagaaagccaaggtcaccatcagtgaggggaag ggccctgatgaagaaaagcccaagaagagcagcctgtgccgaaacgtcgaggggtgtcga gaggagctgcagtcccaggccaacttctcctttgcccctttggtgctggagatgctgaat ttcctgatggatgccattcagatcaacttccagcaagcttcagccatgggcagcagcagc cgggcgcagcaagctctcaacgagctgcacaccttggacaagtcggtggagatgacagac cagctgatggtgccaacgctgggctcccaggagggtgccttcgagaacgtccgcatgaac tacagcggcgaccagggccagaccatccggcagctgatcagcgcccacgtgctgcgcagg gtggccatgtgtgtgctctcctccccccacggccggcgccagcacctggctgtcagccac gagaagggcaagatcacagtcctccagctctcagcactgctgaagcaagcagactccagc aaaaggaagctgaccctcactcgccttgcatctgcacctgtcccctttacagtgctgagc ctgactggaaatccctgcaaggaggactacctggctgtgtgtgggctcaaagactgccac gtgttaaccttcagcagctctggctcagtctctgatcatttggtccttcatccccagcta gccactggcaacttcatcattaaagctgtgtggctgccaggatctcaaacagagcttgct attgtgactgcagactttgtgaagatttatgacctctctgtggatgccttgagtccaact ttctacttccttctgccgagctccaaaatcagggatgtgactttcctcttcaacgaggaa gggaagaacatcatagtgatcatgtcctctgctggctacatctacactcagctcatggaa gaggccagcagtgcccagcatggaccattctatgtcaccaacgtgcttgaagtcaaccat gaggacctgaaggacagcaatgggcaggtggcaggaggtggggtctcagtgtattactcc cacgtgctgcagatgctgttcttcagttactgccagggcaagtcctttgcagccaccatc agcagagccagcctggaggtgcagcgactgttccccatcaacatcaagagctcaaatggg ggcagtaagacctccccagcactgtgccagtggtctgaggtgatgaaccatcctggcttg gtgtgctgtgtgcagcagaccacgggtgtcccgctggtggtgatggtgaagccagacacc ttcctcatccaggaaataaaaaccttgccagccaaagcaaagattcaggacatggtggcc atccgccacacagcctgcaacgagcagcagaggaccaccatgatcctgctgtgtgaagat ggcagcctgaggatctacatggccaatgtagagaatacatcctactggctccagccctct ctgcagcccagcagcgtcatcagcatcatgaagccggtccgaaagcgcaaggcagctgcc attacaactcgcacctccagccaggtgaacttccctattgacttctttgagcacaaccag cagctgacagatgtggagttcggaggcaacgacctgctgcaggtgtacaacgctcagcag atcaagcaccgcctcaattccaccggcatgtacgtggccaacacaaagcctggaggtttc accattgaagtgacaaacaacaacagcaccatggtgatgacagggatgaggatccagatt gggacacaagccatagagcgggctccctcctacctggagatcttcgggcgcaccatgcag ctgaacatgaccagggctcgctggttcgacttccccttcacccgggaggaagccttgcag gctgacaagaagctgaccatcttcatcggagcttctgtggatcctgctggagtcaccatg atggattccatcaaaatttatggcaaaaccaaggagcagtttgggtggcctgatgagccc cccgaggacttcccctctgcctcagtcagcaacgtttgtcccccaaacctgaaccaaggc aacggcaccggggacgccgagtctgccgcccccgcggctgccagcggcactgtcctggag aggctagtggtgagttctttagaagcgctggaaagctgctttgctgtaggaccagtcaac gagaaggagaagaataaggtggcagctcaggaactggccactatgctgctgtccatgcca gctccttccagtgtccagcagcagaccaagagcctcctggccagcttgcacaccagccgc tctgcctaccataaccacaaggatcaagcattgctgagtaaagccattcagtacttgagt tcctcaaccaaagaaggaaaggaccttgatcctgaagtgtttcagaggctggtcatcact gctagatccattgctattatgagacccaacaatctggtccactacacagaatcaaagctg ccacagctggaagcagagggtgaagaagggcaggatgcccagaagcacactgaaggagat ggctgcaccttcattacccagctggttaaccacttctggaagctgcatgcatccaagccc aagaatgccttccttgcccctgcctgcctgccaggtctcactcatgttgaagccacagtc aatgctttggtggatattatccatggatactgcacctgtgagctggactgtatccataca gcatccaagatctacatgcagatgttgctgtgcccggatcctgcagtgagcttttcttgc aagcaagctttgatcagagtgctgagaccgaggaacaagcggagacacgtcaccttgcca tcctccccacgcagcaacactcctatgggagataaggatgatgatgatgatgatgatgca gaagacaagctgcagagctctgggatagcgaacggggagcacatccggcaggagagccag gagcaaagcgaagttgatcatggggactttgagatggtgtctgaatccatggtcctggag acttctgaaaatgtgaataatgggaacccttctcctctggaggctcttctggctggagca gagggattccctcctatgctggatattccaccagatgcagatgatgaaacaatggtggaa ctggctattgccttgagcctgcaacaggatcagcaagggagcagcagcagtgcccttggg ctccaaagcttagggctgtctggccaagcacccagctcctcttcccttgatgctggcacg ctctcggatacgacagcatcagctccagcctctgacgacgagggcagcaccgccgccacc gacggctccacccccctgtctggccgcagcagtgcctatggggacacggcagctgagggc caccccgctggaccaggcagcgtcagctccagcacaggcgccatcagcactaccacaggc cagcaagagggagatggttcagaaggggaaggagaagcagagggagatgtccacaccagc aacaggctgcacatggtccgactgatgttgctggagaggctgctgcagaacctaccccag ctgaggaatgtgggaggagtcagagccatcccttacatgcaggttattctgatgcttacc acagacctggatggagatgatgagaaagataagggagctttagataaccttctctcccag ctgattgcagagctgtgcatggacaaaaaggacgtgtcgaagaaaaacgaacgctctcca gtcaatgaagtgcacttggtggtcatgaggctgctcagtgtgttcatgtccagaaccaaa tcaggatccaagtcttccatttgtgagtcttcctccctcatctctagtgccaccgctgct gcgttgctgagctctggtgctgttgactactgtctgcatgtgctgaagtccttgctggag tactggaaaagccagcagaatgatgaggagcctgtagccaccagccagctcctgaaacct cacactacttcatctccacctgacatgagccctttcttcctccgccagtacgtgaagggt catgctgcagatgtgtttgaggcctacactcagctcctgacagagatggtactgaggctg ccttaccagatcaagaagattgcagacacaaactcccgcatcccacctcccatcttcgat cactcctggttctacttcttgtctgagtacctgatgatccagcagacgcccttcgtgcgc cgccaagtccgcaagctgctgctcttcatctgcggctccaaggacaaatacaggcagctg cgcgacctccacaccctggactcccacgtccgcggcatcaagaagctgctggaggagcaa ggcatcttcctgcgtgccagcgtggtcacggccagctcgggctctgccctgcagtacgac accttgatcagcctgatggagcatctaaaggcctgtgcagagattgccacccagaggaca gtcaactggcagaagttctgcatcaaggatgactctgttctgtatttcctcctccaagtc agcttcctggtggatgaaggggtgtcccctgtcctcctgcagctgctctcttgtgctctg tgtggcagtaaagtgctgtctgtggcttcctcctctggatcatcaagcacctcttccacc tctgctcctgctgcatcaggctctgggcagccaaccacacagagcaaatcctccaccaaa aagagcaagaaggaggagaaggaaaaggagagagagggtgagagcctgggcagccaggag gatcagctgtgtacagctctggtgaaccagctgaacaagtttgctgacaaggagaccctc attcagttcctgcgttgcttcctgctggagtccaactcctcctctgtccggtggcaggct cactgcctggcactccacatctacaggaactccaacaagtctcaacaggaattgctcttg gatctgatgtggtcaatctggccagagcttccagcctatggaaggaaggctgctcagttt gtagatctcctgggatacttctctctgaaaacccagcagactgagaagaagttgaaggag tactcccagaaggctgtggagatcctcaggacccagaaccacattctcaccaaccacccc aactccaacatttacaacacattgtctggactggtggaatttgatggctattacctagag agtgatccttgcctggtctgcaacaacccagaggtgcccttctgttacatcaagctctcc tccattaaagtggacacacggtacaccaccacccagcaagtggtgaagctcattggcagc cacaccatcagcaaggtgacagtgaagataggagacctgaaacgaaccaaaatggtcaga accatcaacctttactacaacaacaggacagtgcaagccatagtggagctgaaaaacaag ccagctcgttggcacaaagctaagaaagtccagctgaccccaggccagacagaggtgaag attgacctgcccctgcccatagtggcctccaacctgatgattgagtttgcagatttctat gagaactaccaagcctccaccgagaccctgcagtgccctcgctgcagcgcctccgtcccg gccaaccccggcgtctgtggcaactgcggggagaacgtctaccagtgccacaagtgcagg tccatcaattatgatgagaaggatcctttcctgtgcaatgcctgtggcttctgcaagtac gctcgcttcgacttcatgctctacgccaagccctgctgcgccgtggaccccatcgagaac gaggaggatcgcaagaaggcagtaacaaacatcaacaccctcctggacaaggctgacaga gtgtaccaccagctcatgggacaccgaccacagctggaaaacctcctgtgtaaagtgaat gaggcagctcctgagaagccacaggatgaatctggtagtggtggagggatcagttctacc tcagccagtgtgaatagatacatcctccagttagcccaggagtactgtggagactgcaag aactcttttgatgagctttccaaaatcatccagaaagtgtttgcctctcggaaggagctc ctggagtacgacctccagcagagagaggcagccaccaagtcctcccgcaccaccgtccag cctaccttcaccgccagccagtatcgtgccttgtctgtgctgggctgtggccacacctca tccactaaatgctatggctgtgcctcagctgtcactgagcactgcatcaccttgctgcga gccctggccaccaactctgccatcaggcacatcctggtgtcccagggcctcatccgagag ctctttgactacaacctgcggcggggcgcggccagcatgcgggaggaggtccggcagctc atgtgccttctgaccagggacaatccagaggccacacagcaaatgaatgacttgatcatt gggaaggtgtctgcagctctgaagggccactgggcaaatccagacctggccagcagcctc cagtatgaaatgctgctgctgacagattccatctccaaggaagacagctgctgggagctc aggctgcgctgtgccctcagcctcttcctgatggcagtgaacattaagactccagtggta gttgaaaacatcaccctcatgtgcctgcgcattctccagaagctgatcaagccacctgct ccaaccagcaagaaaaacaaggatgtgcctctggatgctctcaccactgtgaagccttac agcaatgaaatccatgcacaggctcagctgtggctcaagagggaccccaaagcatcatat gaagcctggaagaagtgcctccctgccagaggtatagatgccagtgggaaatccctcagc aaagctgagattcaccagctctacttgtcagagaagtatgtgtggaagtggaagcagttc ctgagtcgccgtgggaagaggacttgccccctggacctcaagctggggcacaacaattgg ctgcgccaggtgctcttcactcctgccactcaagctgcgaggcaagctgcctgtaccatc gtggaagctctgactaccatccccagccgcaagcagcaggtccttgatctcctgacgagc tacctggatgagctgagcattgctggggagtgtgctgcagagtacctggccctctatcag aagctcatcaaaccagcccactggaaggtctacctggcagcccggggggttctgccctat attggcagcctcatcaccaaggaaatagctcgtttgcttgccttggaggaagccacactc agcacagacctgcagcagggatatgccttgaagagcctcacaggtctcctctcttccttc gtggaggtggagtccatcaagaggcacttcaaaagccgcctggtgggcaccgtcctgaat ggttacctgtgcctgaggaagctggtggtacagaggacaaagctgattgatgagacccag gacatgctgctggagatgctggaggatatgaccacaggcacagagtctgaaaccaaagcc ttcatggcagtgtgtatagagactgcaaaacgttacagccttgatgactacaggactcca gtcttcatctttgagaggctctgcagcatcatctaccctgaggagaatgaagtgactgag ttctttgtaactctggagaaagatccccagcaggaggacttcttgcagggcaggatgcca gggaatccctacagcagtaatgagcctggcattgggccactcatgagggacatcaagaac aagatctgtcaggactgtgacctggtagctctgctggaggatgacagtggcatggagctt ttggtgaacaataagatcatcagtttggatctgcctgtggctgaggtctacaagaaggtg tggtgtcccactaatgagggggagcccatgaggatcatctaccgcatgcgagggctgctg ggagatgccaccgaggagttcatcgagtccctggactccaccactgatgaagaggaggat gaggaagaagtttacaagatggcaggtgtcatggcccagtgtggaggcttggagtgcatg ctcaacaggctgactgggatcaaggacttcaagcaaggccggcacctcttaacggtgctg ctgaaactgttcagttactgtgtgaaggtgaagatcaatcgccagcagctggtcaagccg gagatgaacactttgaacgtcatgctgggaacccttaacttggctctggtggctgagcag gaaagtaaggacagtggaggagcagcagtggcagaacaagtgctcagtatcatggagatc atactggatgagtccaatgcagaacctctgagcgaggacaagggtaacctcctcctaact ggtgacaaggaccagctggtgatgctgctggatcagatcaacagcacctttgtgcgctcc aacctcagcgtcctgcagggcctgctgcgcatcatcccctacctgtccttcggggagctg gagaagatgcagatcctggtggatcgcttcaagccctactgtaactttgataagtacgac gaggagcacagtggagatgataaagtcttcctggactgcttctgtaaaatagcagcaggg ataaagaacaacagcaatggccatcagctgaaagatctcatcctccagaaggggattaca cagaatgccctggactacatgaaaaagcacattcccagtgcaaagaatttggatgcagac atatggaagaaattcttatcccgaccggcgctgcctttcatcctgcgcctgctccgaggg cttgccacgcagcaccctgccacacaggtgctgataggcacagactccatcaccaacctg cacaaactggagcaggtgtccagtgatgaaggcattgggacgctggcagagaatcttctg gaggccctgagggaacatccggaggtgaacaagaagatcgacgccgcccgcaaggagacc cgggcggagaagaagcgaatggccatggccatgaggcagaaggccttgggcactctgggc atgacgacaaacgagaagggtcaggtagtgaccaagactgcgctgctcaaacagatggag gagctgatagaagagccagggctgacctgctgcatctgccgggaaggatacaagtttcag cccaccaaagtgctggggatttacaccttcaccaagcgtgttgccctggaggagtttgag aacaagccccgcaagcagcagggctacagcaccgtctcccacttcaacattgtccactat gattgtcaccttgcagctgtcagactggctcgcggccgtgaggaatgggagagtgcagcc ctgcagaacgccaacaccaagtgcaatgggctcctgccagtctggggacctcatgtgcca gagtctgcttttgctacttgcttagcaaggcacaacacatacctccaggagtgcacagga cagagggaacctacctaccagctgaatgtccacgacatcaaactgctcttcctccgcttt gccatggagcagtcgttcagcgtcgacactggaggaggaggaagggagagcaacatccac ctcatcccatacatcatccacacggtgctctacgtcctcaacaccactcgagccacgtcg agggaggagaagaacctccagagcttcatggagcaccccaaggagaagtgggtggagagt gcctacgaggtggatgggccccattactacaccgtgctggcactgcacatctctccccct gagaagtggaaagccatgagagtggaggtcctcaagaggctcctcgtcacctcccacgcg cgagtggtgtcgccagggggagccagcagactggcagataaggcggtgaaggattacgcc acgtaccgctctggccttctcttctgggccctggtagatctcatttacaacatgttcaag aaggtgcctaccagcaacactgaggggggctggtcctactctctggccgagttcatccgc cacaacgacatgccgatccacgaggccgccgacagggccctgaaaaccttccaggaggag ttcatgccagtggaaacctttgctgagttcctggatgttgctggcctcttatcagagatc aacgatcctgacagcttcctcaaggaccttctgaactccatcccctga

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