Daphnia pulex (common water flea): DAPPUDRAFT_310496 Help Entry DAPPUDRAFT_310496 CDS       T04347                                  Name (GenBank) hypothetical protein   KO K04962   ryanodine receptor 2 Organism dpx  Daphnia pulex (common water flea) Brite KEGG Orthology (KO) [BR:dpx00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:dpx04040]     DAPPUDRAFT_310496    04990 Domain-containing proteins not elsewhere classified [BR:dpx04990]     DAPPUDRAFT_310496 Ion channels [BR:dpx04040]  Voltage-gated cation channels   Ryanodine receptor    DAPPUDRAFT_310496 Domain-containing proteins not elsewhere classified [BR:dpx04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    DAPPUDRAFT_310496 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 EF-hand_8 EF-hand_1 TrAA12 EF-hand_5 Motif Other DBs NCBI-ProteinID:  EFX89429 JGI:  Dappu1_310496 UniProt:  E9FTU9 LinkDB All DBs Position Unknown AA seq 5119 aa AA seqDB search MADKESGSEQDDVSFLRTEDNVCLSCTATGERVCLAAEGFGNRHCFLENIADKNAPPDLS QCVFVIEQALSVRALQELVTAASSESGTGTGSGHRTLLYGNAVLLRHLNSNMYLACLSTS SSNDKLAFDVGLQEQSQGEACWWTLHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE KDVSIVNASFHVTHWSVAPFGTGLSRVKNVGFLFGGEVLRFFHGGDECLTIPSSWSEQPG QNIVVYEGGDVVLQARSLWRLELARTKWAGGFINWLHPMRIRHITTGRYLCYNENKDLCL LPRNEANLAVSAFYLRKEKDDEKKILEDKDLEVLGSPIIKYGDSTVIVQHVETGLWLSYK AFETKKKGVGKVEEKQAVLHEEGKMDDGLEFSRSQEEESRTARVIRKCSSLFNRFITGLD SLANDHQHMTFFENVNLSEMVKCLEDLIDYFAQPEENIEHEEKQLKLRALRNRQDLFQEE GILNLILDAIDKLTTITGQGYMAALAGEAAGQNLETISAYLYQLLAAIIRGNHTNCAQFA QSHRLNWLFSRLGSQASGEGTGMLDVLHCILIDSPEALNMMREEHIKVIISLLEKHGRDP KVLDVLCSLCVGNGVAVRSSQNNIADYLLPGRNLLLQTQLVDHVSSIRPNIYVGKVANSA VFLKWYFELTVDHVEVTTHLMPHLRVGWAKLPGYVAYPGGGEKWGGNGVGDDLYSYGFDG AQLWTGGRSTVVHAGMTEPYIRKGDVIGCALDLSVPIMNFYLNGVKVKGNFKNMNLDGMF FPVVSCSARVSCRFLFGGEHGRLRFPSPYGFSPLYECLLPTQTLALDPCFHFGDLTKSTL AGPLEVLNDTAFVPQPVDTSMIALPTYIETIRDRLAENIHEIWAMNKIEEGWVFGERRDD LHKIHPCLTPFERLPPAEKRYDTQLALQTLKTILALGYHITMDKPPSRIKTVRLPNDPFA QSNGYKPAPLDLANITLSGKLEELIDHLAENTHNVWAKERITQGWTYGLNEDPDNKRSPH LVPYSNVDDIIKKANRDTASETVRTLLVYGYVLEPPTGEAHETALVGGTVGSKNPEYRTY RAEKTYAVSSGKWYFEFEVLTSGPMRVGWARADAKAGYQLGQDDCSWAFDGWREEKFYVG SGESFGKHWSAGDCVGAFLDLVDRTISFSLNGELLMDSMGSETAFTDIQGEEFIPAFTLG VGQRARLVFGQDVNALKYFTSCGLQEGYEPFCVNMSRQMTYWYTRDQPIFENNDDFADSP IEVTRIPGGSDSPPCMKISHKEFETMEKANWEFLRLSLPVTFHDAFISEQEKGRRWQEIR LRQNRLRADNVTRNATLEQTMLKSGFTMSDINELQYGFDSEEQRRTQQTGSRPPVPERAG RMRSIDYNTNGLDINGHVSDASPSKGILHTSGGDPKDKKRGKSPFAFFSRLRDASTERRN KAKTPEPGLANRDGVQKPERSKNLAAKNVNNVRLNDLKVIPPAIPDRRPSRQGSSPMIQP RGIMGGEDFDPLDVECMRLINEYFYGVRIFPGQDPSHVYVGWVTTQFHLQDKTFDQSKDR KVLISRVDEQERIIESVDRHSCYMLRADELYNEVTQDVASKGASQGMFIGCFIDTATGWI SFTCEGKETKHRYKMEVGTKLFPAIFVEATSKEVLQFELGRTPTTLPLSAAVLQNSEKHV VPQFPPRLKVQILKPHQWSRVPNQSLKAHALKLSDLRGWSMLCEDPVSMLAVHIPEEDRC IDVLELIEHERLLSFHAHTLQLYSALCFQSNFRAAHTLCSYVDQKQLLYAIQSEYLSGPL RAGFSDLLIALHIESHAKTMEVTQNEYIIPMSNELKELYSDPDMTHSLSSLRVESIRPQM TTTDIQEHIETIKELSTPFFPLETVKVFAIHALELAVKLNQVHNRDPIGGSNEMLFVPLL KLIDKLLLVGIMEDDDIPPLLSLIDPETWDPTFDPMGKDEHRKGLLQMPLAEGVKLQMCC LLHHLLDNQLRHRVESIVNFSHDFVGEIQSDQLRRYIEIKQSDLPSAIAAKKTREFRCPP VQQMNAILGFKNLPEEERENCPCNEELALIQTTFHESFTSKLLHKMAEEELVEEEPVKEE TKPGLINRMMNVVTLAKKHEEEQVAEENVKSREQIFRKVLIRTIISWAEESVIESYKLVR EMFRLLLRQYDGVGEAMRALQKTYVINSRTTKDVQELWIGLSRIRGLLPVQMSQEEEELM RELLWKMVNNHSFFQHPDLMRNLRVHENVMAIMMNTLGRRAQAQSDAQTQAQVQASGGEA ELIPKEKDTSHEMVVACCRFLCYFCRTSRANQKTMFEHLSFLLENSNILLSRPSLRGSTP LDVAYSSVMDNTELALALREHYLEKIAIYLSRCGLQSNTELMERGYPDLGWDPVEGERYL DFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGDGLLTAITDANKMSERIQVQ KALHSGTGAITIPGLNHPMPQGDDDEDFIDIGAAILSFYCTLVDLLGRCAPAEAVIAQGK NESLRARAILRSLVPLEDLEGVLSLRFTLQNHGSEDGGSDLPSGLIPGHKQSVVIFLERV YGIEDIELFFRLLEEAFLPDLRAATILEKTDGGESDMALALNRYIGNSILPLLITHSRFY AEAENHASVLDATLHTVYRLSKNKMLTKGQREAVSDFLVALTRELQPNMLLKLLRKLTVD VSRLSEYTTVALRLLTLHYERCGKYYGAVGGQGSYGSASDEEKRLTMMLFSNIFDSLSKM EYDPELFGKALPCLTAIGCALPPDYALATTLEDEWYKSAPPDSNGPYDPQPINTMKVSLN TELTNLVQKFSEHYHDAWAKRKIENGWNFGDAWSDETKSHPRLKPPHMLSDYERERYREP IRDSLKALVALGWSIEFADYDAANSNRNSMRRSSTVTFVSFSEKDGGTTPYNYNPNPVDM ANLTLSREMQNMAERLAENSHDIWAKKKKEEMASSGGGLHPQMVPYDLLTDKEKRKDRER TQELLKYLQFMGYKLHRMGKSQVQQNPDAVALEGENASSSDRRFAYSLLEKLIQYLDIAA FNMKHLRPSTNYSRRSSFKTSTRDVKFFSKVVLPLMEKYFSTHRHYFISVATATSSIGAA SMKEKEMVASLFCKLASLIRYKFSAFGSDTRIAVRCLQVLVRATDAKSLVKNCYEFIRTS MLMFFNNAADDLSQCLSNLYEMKYNLLRGTHLKTSSSLCYVQMVLLPVLTALFDHLSVYE FGSDLLVDDIQVACYKILNNLYTFGTDSSVYKDRKFIKIEIDRHRPSIGSCLGAFASTFP VAFLEPHLNNHNPYCIHGKLQESSLEAQDVMSKLESSMPTLETLLAQVEQFVASEKSYTD APHVIDVMLPMLCSYLPFWWAQGPDNQDPVGGNHITMVTSEHMNQLLKNVLNLIKAHVGS ELAPWMTRIAGFTQQIIINTSEELLKDPFLPLALKIRKRTEQMFHKEETLRGFLKSTTED TSQVEGQLQGDWYLLVRDIYAFYPLLIKYVDLQRNHWLRHDVPEGEELYAHVAEIFNMWS NSQYFGKEEQNFISANEIDNMTLIMPTSASRKATVVTDQTPAGASGKKKKKSRDRKRDKD KEIAASLMVACLKRLLPVGLNLFPGREQELVQHCKDRFLKKVIEREIIDFAKTQLTLPDK IDPSDAMSWQHYLYSKLGSKKPSPAIAGVADSAKKNANHQAILDELVERIVAMAKVLFGL HMIDHPQQQQKDAWRSVVSSQRKRAVIACFQQKSLHSLPRHKAINIFLRTYQELWLADEN VGQEVIIEDLTQSFEDAELKKKEVEEEEGKPDPLLQLVTTFNRGATTERAGTTFEDELYM AYAVIMSKSCGEEEEEDEEGGDEEGGASIHEQEMEKQKLLFHQSRLASRGVYEMVLQFIS AAKGAQSDMVMNTLELGISILRGGNVDIQMQMLNYLKEKKDAGFFTSIAGLMNSCSVLDL DAFERNTKAEGLGVGAEGAAGEKNMHDAEFTCVLFRFIQLTCEGHNLEWQNYLRTQAGNT TTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFLKAIGVASQVFNTLSEVIQ GPCTLNQQALAHSRLWDAVGGFLFLFANMQDKLSKHSSQLDLLKELLNLQKDMVIMMLSM LEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTGSAAFQESETTKDGWITP KEFREKMEAFKSYSVEEMDFMLSCCDTNHDGKIDYIEFTERFHNPAKEIGFNLAVLLTNL SEHMPSDPRLQRFLETAGSVLNYFESFLGRIEIMGSSKTMERVYFEINESNIEQWEKPQI KESKRAFFYSIVTEGDKEKLEAFVNFCEDAIFEMQHASGLMASDEEGGISQARQAAYKLP TDEEEQGPMDIMRQKLKGFKDTLVFGLSMLSPSNIRKQIRELKQKTYPELFVGFFKLFFY MFYYTGYFGVYLIKHFFRILLSLMRGPQPEKVPEKPVTEETTMLILRPPPPPAPAILPTE ANAEPVTTVALVGSPTDPTAQAADGSTTVPPAGSPDPTQPDATGAQPTGAEQASAAPPPT ASSLFVGTLTDPAEEAAKAAAAAEVQAQQEATMAALDEAKATSVSHTAASPVAQVNLGEY VRKAICFLARNFYTLKYVALVLAFCINFVLLFYKVFAAEDEAGGEAGGEVGGSTEAEGSG GLADLAESIVDADGDGDGDGDGDEEDAEEYIHVDERFSYLANVLRGMAVLHSLISLFMLI AYYHLKVPLAIFKREKEIARRLEFDGLYIAEQPEENDMRAYWDKLVISAKSFPVNYWDKF VKKKVRQKYSETYDFDAISNLLGMEKSSLSQEEEVPSGFVNSLLSVDWRYQVWKAGVTIT DNSFLYSLWYFSFSILGNYNYFFFAAHLLDVAVAIASLRTILQSVTHNGKQLLLTVMLLT IIVYLYTVIAFNFFRKFYVQEEDDNVDKKCHDMLTCFVFHIYKGVRAGGGIGDEIESPDG DEYEVYRIMFDITFFFFIIVILLAIIQGLIIDAFGELRDQLASVSENLESECFICGIGKD YFDSVPHGFDTHVQKEHNLANYLFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFFPVGD CFRKQYEVELGGGESEKKG NT seq 15360 nt NT seq  +upstreamnt  +downstreamnt atggccgacaaggagagcggttccgagcaggatgatgtttccttcctgagaacggaagat aatgtgtgcctgtcgtgcactgcaaccggtgagagggtctgtctcgccgccgaaggattt ggaaatcggcattgctttctggaaaacatcgccgataagaatgccccaccggatttatca caatgcgtcttcgtcatcgaacaggctctttccgttcgggctttacaagaacttgtcaca gcagcttcgtccgaatcgggaacaggcacaggctctggccacaggactttactttatggc aatgcagtcttgttgaggcatctcaacagtaacatgtatttggcctgtctttctaccagc tcttcgaatgacaaattagcttttgatgttggcttgcaagagcaatcacaaggcgaggct tgttggtggacacttcacccagcttcaaaacagcgttcggaaggtgaaaaggttcgagtc ggtgacgatttgattctagtttcagtcgctactgaacgttacctgcacaccacgaaagaa aaagatgtatcgattgtcaacgcttctttccatgttacccactggtcggtggctcctttt ggaacgggattaagtcgcgtcaaaaacgttggatttctgttcggtggcgaagttttacgc tttttccatggaggcgacgagtgtcttacgattccgtcgtcatggtcagagcaacctgga caaaatatcgtggtctacgaaggaggtgatgttgttttacaagctcgctctttgtggcgg ttggaattggcccgtaccaaatgggctggtggatttatcaactggcttcatcccatgcgc atccgacatatcaccactggccgctacctttgctacaacgaaaataaagatctctgtctc cttcctaggaatgaggccaacttggcggtcagcgcattctacttgcgcaaagaaaaggat gacgagaagaaaatattagaagacaaagatttagaagttttgggctctcctattatcaaa tacggtgacagcaccgttattgttcaacacgttgaaactggtctctggctttcatacaag gccttcgagacaaagaagaaaggtgtcggaaaggtagaggagaaacaagccgttttgcat gaggaaggaaaaatggacgacggacttgagttcagtcgaagccaagaggaggagtctcgt acagctcgtgttatcaggaaatgcagttcccttttcaacagatttatcacaggattggat tctctagcaaacgatcatcaacacatgacgttttttgaaaatgttaacctgtcagaaatg gtaaaatgtcttgaagatttgatcgactatttcgcccagccagaagagaatatagagcac gaagaaaagcaattaaagttgcgagccctacgcaaccgacaagatttgtttcaagaagaa ggcatcctcaatcttattttggatgcaattgataaacttacaacaattactggccaaggg tatatggcagctctagctggagaagctgccggccagaacttggaaaccatttcggcctat ctctatcagctattagccgccattattagaggaaaccacacgaattgcgctcaattcgcc caatcacatcgattgaactggctatttagccggctcggctcgcaagcttccggagaaggt acaggcatgttggacgtactccactgcattcttattgactccccagaagcactgaacatg atgagggaagagcacatcaaagtaattatatctcttcttgagaaacacggaagagatccc aaagtcttggatgttttgtgctccttgtgtgtcggtaacggagttgctgtccgcagctcg caaaacaatattgccgattatcttttgcccggaagaaacctgttacttcagacacagttg gttgatcatgtgtctagcatccgacccaacatttatgttggcaaagtcgccaattcagca gtttttcttaagtggtactttgagctcacagtggatcatgtcgaggtaacgacacatctc atgccacacttgcgcgttggatgggccaaattacctggttacgtggcttatcccggagga ggagaaaaatggggcggtaatggcgtaggtgatgatttgtattcttacggttttgacgga gcccagttgtggacaggcggtcgaagcaccgttgtccatgccggaatgaccgagccttac atccggaaaggagatgtaatcggttgtgctctagatctttcggtccccattatgaatttc tatcttaacggagtcaaagtcaagggaaactttaaaaatatgaacttggacggtatgttt ttcccagtggtcagctgttctgcacgagtcagttgccgattcttgtttggaggtgaacat ggtcgtttaaggttcccttcaccgtacggattctctccgctgtacgagtgtcttctaccg acccagactttagctcttgatccttgtttccactttggggacttgaccaaaagtacattg gcaggccctcttgaagtgctgaatgacactgctttcgtaccgcaacctgtggatacgtcg atgattgctctacctacttacatcgaaactattcgcgatcgtctggcggaaaatattcac gaaatatgggccatgaacaaaatcgaagaggggtgggtgtttggtgaaagacgagatgat ttacacaaaatccatccttgtttgactccgtttgaacgattgccgccagctgagaaacgt tacgacactcaactggctttgcagacactcaagacaattcttgccttgggctatcacatt actatggacaagcctccatcgcgcatcaaaacagtgcgattgcccaatgatccttttgcc cagtcgaacgggtataaacccgccccattggatttggccaatattactcttagtggcaaa ttagaggaattgattgatcatttggcagaaaacacccacaacgtctgggccaaagaacgt attacacaaggatggacttatggcctcaacgaagatcctgacaacaagcgtagtcctcac ttggtcccatattctaatgttgacgacatcattaaaaaagccaacagagatactgccagc gaaactgttcgtactttgctcgtttacggttacgttttggagccacccacaggggaggca catgaaactgctctagttggtggtacggtgggctcaaaaaatccagaataccgaacatat cgagcggagaaaacatatgccgtgtcgtctggaaaatggtatttcgagtttgaagttctt acatctggccctatgcgagtgggttgggctagagctgatgccaaagctggttatcaatta ggccaagacgactgcagctgggctttcgacggatggagggaggagaaattttacgtggga tctggcgaatctttcggcaaacactggtcggctggagattgtgttggcgccttcctcgat ttagtcgatcgcaccatcagtttttctctaaatggcgaattgcttatggattctatggga agtgaaaccgcatttacagatattcaaggcgaagaattcattccggctttcacattggga gttggacaaagagcaagacttgtttttggacaagatgttaatgcgcttaaatatttcacc tcttgcggtctccaagaaggatacgaaccattctgcgtaaatatgagtcgacaaatgact tattggtacacacgcgatcaacccattttcgagaataatgacgatttcgcggattctccc atagaagtgacgcgtatccctggtggatcagattctccaccttgtatgaagatttctcac aaggaatttgaaacaatggaaaaagccaattgggaatttctccgattgtccttgccagtt acctttcacgatgccttcatatcagaacaggagaaaggtcggcgatggcaggaaatccgt ctacgacagaaccgtcttcgggctgataacgtgacgcgcaatgccacgctggagcaaact atgttgaaatcaggattcacgatgtcggatatcaatgaacttcagtatggcttcgactct gaagaacaacgcagaacccagcaaactggatctagaccgccggttcccgaacgagccggt cgtatgcgcagcatcgattataatacaaacggtcttgatattaatggtcatgtaagcgat gctagtcccagcaaaggaatattgcacacgagcggaggagatcctaaggataagaaacgt gggaagtcgccttttgcattcttttcacgccttcgggacgccagtaccgaacgtcgcaac aaagccaaaactcccgagccaggattggccaaccgcgatggagtacagaaaccagaaagg tcgaaaaatctcgcagccaagaacgtgaataatgttcggttgaacgatctgaaagtgatt ccgcctgcaattcctgatcggcgaccatcgagacaaggatcaagccccatgatacagcca agaggaataatgggaggcgaagatttcgatcccttggatgttgaatgcatgcggctaatc aatgaatatttctatggtgttcgaattttcccgggtcaggaccccagtcacgtttacgtc ggttgggtcacgacacaattccacttgcaagataagactttcgatcagtccaaggataga aaagttcttatttccagagtggacgaacaagagcgtattatagaaagtgtggaccgtcac agctgctacatgttgcgagctgacgaactctataacgaagtaacacaagacgtagccagc aaaggagcgtctcaaggaatgtttattggctgcttcattgacacggctacgggatggatt agtttcacctgcgaaggaaaagaaaccaaacaccgttacaagatggaagtgggaacaaaa ctcttccctgccatttttgttgaggccaccagtaaggaagtgttacaatttgaattaggc cgcactcccaccacattacctctttcagctgcggtactacagaattctgagaaacacgtt gtgcctcagttcccgcctcgactgaaagttcaaattttgaaaccacatcagtggtcacgc gtcccgaatcaatctctcaaggcacatgccttgaagctgtctgatcttcgtggctggagt atgttgtgtgaagatcctgtttctatgctggccgtccacataccggaagaagacagatgc atagatgttcttgagctaattgaacacgagcgacttttgagtttccacgcgcacacttta cagctgtattcagctttgtgctttcaatctaatttcagagcagcacacactctttgctcg tacgtggatcaaaagcaattgctgtacgccatacagtccgagtatctttcagggccattg cgagccggcttctctgatttactgattgctctacacattgaatcacatgccaagaccatg gaagtgactcaaaatgagtacatcattccgatgagtaacgagcttaaggaattgtactcg gatcctgatatgacacacagcttgagttcactgcgggttgaatccatcaggcctcaaatg actacaactgatatccaagagcacattgaaactatcaaggaattgagcacaccctttttc cccttggagacagtaaaagtatttgctatccatgctttagaactcgccgttaaactgaat caagttcataaccgcgatccaattggcggaagtaacgaaatgcttttcgttccccttctc aaacttattgataaactgttgctcgttggaattatggaggatgacgatattccgcctttg ctgagtctgattgatcctgaaacttgggatccaacgtttgatcccatggggaaagatgag caccgtaaaggacttcttcagatgcccttagcagagggtgtcaaactgcaaatgtgctgt ttactgcatcatttattggacaaccagcttcgccatcgggtcgaatcgattgtaaatttc agtcacgattttgtcggcgagatccaatcggatcaattgcgtcgttatatcgagatcaaa cagtctgatcttccctcagctatagctgccaagaagacgcgcgagttccgttgcccgcca gtccaacaaatgaatgccatcttgggattcaaaaatttgccggaagaagaaagagaaaac tgtccatgtaatgaggaactagcgttgatccagacgactttccacgaatctttcacgtcc aagctccttcacaaaatggcagaggaagaattagtcgaagaggaaccagtgaaagaagaa actaaacccggactgattaatcgcatgatgaatgttgtcacgctagctaagaaacacgaa gaagaacaagtagccgaagaaaatgtaaaatcccgcgaacagatatttcgcaaagtgctc attagaactattatttcctgggcagaagagtcggtaatcgaaagctacaaattggtgcgt gaaatgtttcgattgttactgcgtcagtatgatggcgtaggagaggccatgcgagctttg cagaaaacatacgtcattaacagtcgcaccacaaaggacgtgcaggaactctggattggt ttgagtcgtatccgcggcctattgcctgtacaaatgtcgcaagaagaagaggaattaatg cgagagctcttatggaagatggtcaataaccattccttcttccaacatcctgatcttatg cgcaatcttcgtgtccatgagaacgtcatggctatcatgatgaatactttaggacggcga gctcaagctcagtcggacgcacaaacacaggctcaagttcaagcttcaggaggagaagct gagttgattccgaaagagaaggatacttcacatgaaatggttgtagcctgctgccgtttc ctttgttatttctgccgaacttcccgtgcaaaccagaaaaccatgtttgagcacttgtct ttccttttggaaaattctaatattctcttatcaagaccttcactgagaggtagtactcca ttggatgtagcctattcttcagtaatggacaacactgaattggcattggctttaagagaa cactaccttgaaaagattgccatctacttgtcccgttgcggtttgcaatccaataccgag ttgatggagcgaggctatcccgatttgggctgggatcctgttgaaggtgaacggtacttg gactttctccgtttctgcgtttgggtcaatggcgaaagtgtagaagaaaacgcaaatttg gttatccggctattgattcgccgtcctgaatgtctcggtcctgctttgcgtggtgaagga gatggtcttctaacagccattaccgacgccaataaaatgtcggaacgtatccaagtgcag aaagcccttcattcaggaactggagccataacaattcctggactaaatcacccgatgcca caaggtgacgatgacgaagatttcatcgacattggagctgctattctcagcttctattgc acccttgtcgatttgctcggacgatgtgcgccggccgaggccgtcatcgcccaaggaaag aatgagtctcttcgtgctcgtgcaattttgcgatccctggtacccttggaagatcttgag ggtgtgcttagtttgcgctttactctacaaaaccatggatctgaagatggtggatccgat ttgccatcgggacttattcctggtcacaaacagagcgttgttatcttcttggaacgcgtt tatggcatcgaagatatcgaattattcttccgtcttttggaagaggcattcttaccggat ttgcgagctgctactattctcgagaaaacggatggtggcgagtcagacatggctcttgct cttaatcgttacatcggaaattccatcttacctttgttgatcacccattctcgtttttat gctgaagctgaaaatcacgctagcgttttggacgccacgctccatacagtctatcgtctt tctaaaaacaagatgttgactaaaggacaacgtgaagccgtttctgactttttagttgca cttaccagagagttgcaaccaaacatgctgctcaagctcttgagaaagctaacggtagac gtttctcgtctttccgaatacactacagtggctctcaggcttttgacccttcactacgaa cgttgcggcaaatattatggcgctgttggtggtcaaggcagttacggttctgctagcgac gaagaaaagcgacttaccatgatgctcttctccaacatctttgattccctttccaagatg gagtacgacccagaattgtttggaaaggccctaccttgcctgacggctatcgggtgcgct cttcctccagattacgcactggccacaacattggaagatgaatggtataaatcagctcct ccagattccaatggtccatatgatcctcagccaatcaacaccatgaaggtttccttgaac accgagcttactaatctagtgcaaaagttttctgagcactatcacgatgcttgggctaag cgaaagattgaaaacggctggaattttggtgacgcctggtcagatgagacaaaatcccac ccgcgattaaagccacctcatatgttgtcggattacgaacgggagagatatcgggaacct atcagagattccttgaaggctctggtggcattaggctggagtattgagtttgcagattat gatgccgccaatagcaatagaaatagcatgagacgctctagcacggtaacttttgtttct ttttcggagaaggacggtggcactacaccatataattacaaccccaatccagtggatatg gccaatcttactttgagcagggaaatgcaaaatatggccgaacgcttggctgaaaattcg cacgatatttgggcgaaaaagaagaaagaagaaatggcctcttctggtggaggtttgcac cctcagatggtaccatacgacctgctgactgacaaagaaaagcggaaagatcgtgagcga actcaagagttgctgaaatacctccaatttatgggctacaaattgcacagaatgggaaaa tcacaagtacagcaaaatccggacgcagtggcccttgaaggagaaaatgcatcatctagc gatcgtcggtttgcttacagcttgttggagaagctgatccagtatttagatattgctgcc ttcaacatgaaacatttgcgacccagcaccaactatagccgcagaagcagcttcaaaact tcaactcgagacgtcaaatttttctcaaaggttgtgcttcctttaatggaaaaatacttt agcacccaccgccattatttcataagtgtcgcaactgctactagcagtattggagcagcc tcaatgaaagagaaagaaatggtagccagtctgttttgcaaactagcttctctgatacgc tacaagttttccgcgtttggttccgacacccgcatcgccgtgcgatgcttacaagtactg gttcgcgctaccgacgccaaatctctagttaagaattgttacgaattcatccgcacatcc atgttgatgtttttcaacaatgctgccgacgacttgagccagtgcttgagtaatttgtac gagatgaagtacaatttgcttcgaggaacccatttgaagacttcttcctctctctgttac gttcaaatggttcttcttccggttttgaccgccttatttgatcacctgtccgtctacgag tttggtagtgatcttctagttgacgacatacaggtcgcgtgctacaaaattttaaacaac ttgtacacatttggaaccgattcatctgtttacaaggacaggaaattcattaagattgaa atcgatcgtcatcgaccgtcgattggtagctgcttgggtgccttcgcttcaacgtttccc gttgctttcctggaaccccatctgaataatcacaacccgtactgcattcacggaaaatta caagaatcctcccttgaagctcaagatgtcatgtccaaattagagtctagtatgccgacg ctcgagactctccttgctcaagtggagcaatttgtcgcttccgagaagagttacacagac gcccctcatgtgattgacgtcatgttacctatgctgtgctcttatttaccattttggtgg gctcagggtcctgacaatcaagaccctgttggaggaaatcatattaccatggttaccagt gagcatatgaaccagctgctgaagaatgtgctcaacttgatcaaagcccatgttggctcc gaattggctccttggatgacccgcatcgccggattcactcaacaaattatcattaacact tcagaagagcttctcaaggatcctttcctacctcttgctctaaagattcgtaaacgaaca gagcagatgtttcacaaggaagagactttgcgtggcttcttgaaatcaaccactgaagac acgtcacaagttgagggacaattgcaaggcgactggtatctcttggtcagagacatttat gccttctatccgctgttgatcaaatacgtcgatctgcaaagaaaccactggttacgtcat gatgttcccgaaggagaagagctctacgctcatgtcgccgagatctttaacatgtggtcg aattcccagtattttgggaaggaagagcaaaactttatctccgccaatgagattgacaac atgaccctgattatgccaacttcagcaagcaggaaagcgactgttgttacggatcaaacc ccggctggagcgtcggggaaaaaaaagaagaagtcacgcgatcgcaagcgtgataaagac aaggaaatcgcagcctctttaatggttgcttgtctgaaacgacttttacctgtcggattg aatcttttccctggcagagagcaagaacttgtacagcactgtaaagaccgtttcttaaaa aaagtcattgagcgggaaatcatcgactttgctaaaactcagctgactcttccggacaag attgacccatcagacgccatgtcgtggcaacactatttatattctaaactaggttctaaa aaacccagccccgccatagccggagtggcagactcagcaaagaagaatgccaatcaccaa gctattttagacgaattggttgaaagaattgtagccatggccaaagttttgtttggtttg catatgattgatcacccacagcagcagcaaaaggacgcctggcgttctgtggtttcctct caaagaaagcgcgccgtcattgcctgttttcaacaaaaatcactacactctttacctaga cacaaagccatcaacatattcttgcgaacctatcaagagctttggcttgccgatgaaaat gttggtcaagaagtcatcatcgaagacttgacccaatcgttcgaagatgctgaattgaaa aagaaagaagtcgaagaagaagaaggtaaacctgatcctcttctgcaactagtgactact tttaatcgaggcgctactaccgaaagagcgggaacgactttcgaagacgaactatacatg gcttatgctgttatcatgtctaagtcttgtggcgaagaggaagaggaagacgaagaaggt ggagatgaagaaggaggcgcctcaattcacgaacaagagatggaaaagcagaagttgctg ttccaccaatctcggcttgcttcccgcggtgtctacgaaatggtcctgcaatttatttca gccgccaagggcgcccagtcggacatggtgatgaacacgctagaattgggtatttccatt cttcgcggtggtaatgtcgatatccaaatgcaaatgttgaattatctgaaagagaaaaaa gatgctggatttttcacctcaatcgcgggattaatgaattcctgcagtgtcttggacttg gatgcttttgagcgcaatactaaagcggaaggacttggtgtcggtgctgaaggtgcagcc ggagagaaaaacatgcacgatgccgaatttacctgtgttctattccgatttattcagctg acttgcgaaggccacaatctcgaatggcaaaactatttgagaactcaagctggtaatacg accacagtgaacgtagtcatttgcactgtcgattatctgttgcgcttgcaggaatctatt atggatttctactggcattactctagcaaggaaattattgatcccgcgggtaaagcgaat tttttgaaagcgattggtgttgccagtcaggtattcaacactctaagtgaagttattcag ggcccgtgtacgcttaatcaacaggcattagctcattcaagattgtgggatgctgttggc ggtttcctcttcctgtttgctaacatgcaagacaaattgtcaaagcactctagccagctt gacctgcttaaagagttgctcaatcttcaaaaagacatggttattatgatgctctccatg cttgaaggaaatgtcgtaaacggaacgatcggaaagcaaatggttgacacacttgtagaa tctgcttctaacgttgagcttatcctaaaatattttgacatgttccttaagctaaaggac ttgacgggctcagcggctttccaggaatcggaaaccaccaaagatggatggatcactccg aaagaattcagagaaaagatggaagcttttaagagctactcagttgaagagatggatttc atgctgtcttgttgcgatactaatcacgatggaaaaattgactacatcgaattcacggag agattccacaatccggctaaggaaatcggttttaacttggcggttcttttgactaatctt tcagaacacatgccaagcgatcctcgactgcaacgtttcctggaaacagcaggtagcgtt ctcaattatttcgaatcgttcttaggacgcatcgaaattatgggcagtagcaaaacgatg gaacgagtttatttcgaaattaacgagtcgaacattgagcaatgggaaaaaccgcaaatt aaggagtcgaagcgtgccttcttctactcaattgttacggagggagataaggaaaagttg gaggcctttgtcaacttttgcgaggacgccatttttgaaatgcagcatgcaagcggattg atggcctccgacgaagaagggggaatatcgcaagcccgccaagctgcatacaaactgcca actgacgaagaagaacaggggccaatggacataatgcgccaaaagctcaagggtttcaaa gacacgcttgtttttgggctatccatgttatctccatccaacatccgaaaacagattcga gaactcaagcagaaaacttatcccgaactctttgtcggtttcttcaagctcttcttttac atgttttactacaccggctattttggcgtctacttgatcaaacatttcttccgcattcta ctctccttgatgcgcggtccccaaccggagaaagtgccagagaaaccggtcactgaagag acaacaatgctcatacttcgaccccctcctcctcccgctccagctatattgccaaccgag gcgaatgcagaacccgttactacagtagcattggtgggttcgcctactgaccctacggct caagccgccgacggatctaccacagttcctcctgccggatcacccgatcctacccaaccg gatgcaactggagcccagcctactggtgcagagcaagcttctgctgctccaccacctaca gcttcgagtctgtttgttggcaccctaacagatccagcggaagaagccgctaaggcagct gctgctgctgaagtgcaagctcaacaggaggctaccatggcggctcttgatgaagccaag gccacctcagtgtcgcacacggccgcatctccagttgcacaggtgaatcttggagaatat gtcagaaaggccatttgtttcctcgctcgtaacttttacacactcaagtacgtggccttg gttttggctttctgcatcaattttgtcctgcttttctacaaggtatttgctgctgaagac gaagctggcggagaagctggcggagaagttggtggttcgaccgaggctgaaggaagtgga ggattagctgacttagcagaaagtatagttgatgcggatggtgatggtgacggcgatgga gatggcgatgaagaagatgcagaggaatacattcatgtcgatgaaaggttctcttacctc gcaaacgtccttcgcggaatggctgtgctgcactcgctgatatcgctcttcatgcttatt gcctactatcacctcaaagtcccgctggccatcttcaaacgtgaaaaggagattgcacgt cgcttggaatttgacggactgtacattgctgaacaaccagaagagaatgatatgcgggct tattgggacaaattggtaatttcggcgaaatccttccccgttaattactgggataagttt gtaaagaagaaagtccgccaaaagtacagtgaaacctacgattttgatgccatcagcaac cttctgggcatggagaaaagttctctatctcaggaggaggaagtgccctccggattcgta aactcgctcttgagcgtggactggcgctaccaggtgtggaaagcgggggtgaccattacg gacaactccttcttgtactcgctgtggtactttagcttctcaatcttgggcaactataat tatttcttcttcgccgctcatttgctggatgtggccgtcgccattgcctcgttgagaacc atcttgcagtccgtcactcacaatggcaagcaactgttgttgaccgttatgctgttaacc attatcgtctacttgtacacggtcatcgccttcaatttcttccgcaagttttacgtgcag gaggaagacgataacgtggacaagaaatgtcacgacatgttgacctgcttcgtcttccac atttacaaaggtgtccgagctggtggtggtatcggtgatgaaattgaatcgcccgacggc gacgaatatgaagtgtatcgtattatgttcgatatcaccttcttcttcttcattattgtt attttgctggccatcatccagggtttgattattgatgctttcggagaattgcgtgaccag ttggccagcgtttctgaaaatctcgagtccgagtgcttcatatgcggtataggaaaggat tacttcgattctgttccacacgggttcgatacgcacgtacaaaaggagcacaatctggca aattatctgttcttcttgatgcatttgatcaacaaaccggacacggagtacacgggtcaa gagacctatgtatggaacatgtaccagcaacgttgttgggacttcttcccagtcggagac tgcttccgcaaacaatacgaagtggaattgggtggaggagagagcgagaagaaaggataa

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