Deinococcus radiodurans: DR_0768
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Entry
DR_0768 CDS
T00025
Name
(RefSeq) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
dra
Deinococcus radiodurans
Pathway
dra00300
Lysine biosynthesis
dra00550
Peptidoglycan biosynthesis
dra01100
Metabolic pathways
dra01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
dra00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DR_0768
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DR_0768
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DR_0768
Enzymes [BR:
dra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DR_0768
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-GeneID:
1798523
NCBI-ProteinID:
NP_294492
UniProt:
Q9RWA1
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Position
1:782459..783760
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AA seq
433 aa
AA seq
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MLDPRSVPFAAQIHPQARPARRLTWDSREAGPDTAFVALPGEKMHGNRFVERALAAGAPF
VLTDLDVPRAVRVDDARGALFAWARSERAKNPLVVGITGSAGKTTAKSYAAAALDAHFMP
VFNTMPAIACFLVQYGASQKPLVVEMGIDHIGEMAELMDLVRPDVGVVTTIGPAHLEQFG
MVETIAHEKGQILTARRALVGSQAAAFFPKAQFPHVDSYGFGDVTFRGEGLELSPQAARF
RFGGMGVILPLASRVQAEAAVLGMVLAREAGIALADAAVRMSAVEVPGGRYRLHPGRFTV
IDDAYNASPVAVRAALDALHALKPEGEVGRRISVLGRMLELGPTERELHAEVGSYAREQA
DLTYGVGEFAQELGERAFATVPELLADLLNEVRDGDIVLVKASRGISLTPEQRAVTGVGL
DVVVEALLDQRDR
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgcttgacccccgttctgttccttttgccgctcagattcacccccaggcccgcccggcg
cggcggctgacctgggactcgcgcgaggcggggccggacacggcgttcgtcgcgctgccc
ggcgagaagatgcacggcaacaggttcgtcgagcgggcgctcgcggcgggggcgcccttc
gtcctgaccgacctcgacgtgccccgcgccgtgcgggtagatgatgcgcggggggccctg
ttcgcctgggcgcggagtgaacgggcgaaaaacccgctggtggtgggcatcaccggcagc
gcgggcaagacgaccgccaagagttacgcggcggcggccctggacgcccacttcatgccg
gtgttcaacaccatgcccgccatcgcctgttttctggtgcagtacggcgcgagccaaaag
ccgctggtggtggagatgggcatcgaccacatcggcgaaatggccgagctgatggacctc
gtgcggcccgatgtgggcgtcgtgacgaccataggcccggcgcatctggagcagttcggc
atggtggagaccatcgcccacgaaaagggtcagattctgacggcgcggcgggcattggtc
ggctcgcaggccgccgcctttttccccaaggcccagtttccccacgtggacagctacggc
ttcggcgacgtgacgttccggggcgaggggctggaactctcgccgcaggccgctcgcttc
cgcttcggcggcatgggcgtgattttgccgctcgcctcgcgggtgcaggccgaggccgcc
gtgctggggatggtcctcgcccgcgaagctggcatcgcgctggccgacgccgccgtgcgg
atgagcgcggtggaagtgcccggcgggcgctaccgactgcatccgggccggtttaccgtc
attgacgacgcctacaacgcgtccccggtggcggtgcgcgccgcgctcgacgccctgcac
gcgctgaagccggagggcgaggtaggccgccgcatcagcgtgctgggccggatgctggaa
ctcggccccactgagcgtgagctgcacgccgaagtcggcagctatgcccgcgagcaggcc
gacctgacctacggggtgggcgagttcgcgcaggagctgggcgagcgcgccttcgccacc
gtgcccgagctgctcgccgacctgctgaatgaagtccgtgacggcgacatcgtgctcgtc
aaggcgagccggggcatttccctgaccccggagcagcgcgcggtgacgggcgtggggctg
gacgtggtggtggaggccctgctcgaccagcgcgaccgctga
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