KEGG   Desmodus rotundus (common vampire bat): 112297419
Entry
112297419         CDS       T05907                                 
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro00230  Purine metabolism
dro01100  Metabolic pathways
dro04024  cAMP signaling pathway
dro05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:dro00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    112297419 (PDE10A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    112297419 (PDE10A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    112297419 (PDE10A)
Enzymes [BR:dro01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     112297419 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     112297419 (PDE10A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 112297419
NCBI-ProteinID: XP_024408009
LinkDB
Position
Unknown
AA seq 853 aa
MSKKRKALEGGGGGGESPLPEEEPPAWSGGRSSQEQASRLPFTLKSVSEGPAVLGLSSRT
DAQEQTSNEPEGGSLDPRDAAGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKN
NKPEDETAPKEVSRYQDTNMQGVVYELNSYIEQRLDAGGDNQLLLYELSSVIKIATKADG
FALYFLGECNNSLCVFTPPGIKEGRPRLVPAGPIAQGTTTSAYVAKSRKTLLVEDILGDE
RFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELHRHWGKEAFCLSHQEVATANLAWAS
VAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQ
VDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPR
FNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALA
LHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMRFTLPGRLCKEIELFHFDIGP
FENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYSIL
QNNCGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVS
ILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSH
RDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDE
VPQGQLGFYNAVAIPCYTTLMQIFPPTEPLLRACRNNLSQWEKVIRGEESPVWLTSQPAA
PGPSETLPVKIDD
NT seq 2562 nt   +upstreamnt  +downstreamnt
atgtcgaagaaacgcaaagccctggagggtggaggaggtggaggagaatccccgctcccc
gaggaggagccccctgcctggtccgggggacgcagcagccaggagcaagccagccgcctc
cccttcacactgaagagtgtgagcgaagggcccgccgtgctgggcctgagcagcaggaca
gacgcccaggagcagacgagcaatgagccggagggaggcagcctggacccccgagatgca
gcaggtttgacagatgaaaaagtgaaggcgtatctttctcttcacccccaggtattagat
gaatttgtttctgaaagtgttagtgcagagacggtagaaaaatggctaaagaggaagaac
aacaaacccgaagacgagacggctcctaaggaagtcagcaggtaccaagatacgaatatg
cagggcgttgtgtatgagctgaacagctacatcgagcagcggctggacgcgggcggggac
aaccagctgctcctgtacgagctcagcagcgtgatcaagatagccaccaaagctgatgga
tttgcactgtatttccttggagagtgcaataatagcctgtgcgtgttcaccccacctgga
atcaaggagggacgaccccggctcgtccccgcggggcccatcgcccagggcaccaccacc
tccgcctacgtggccaagtcccggaaaacgctgctcgtggaagacatcctcggggatgaa
cgctttccaagaggcactgggctggagtcagggacgcggatccagtccgtcctctgtttg
cccatcgtcactgccatcggtgacctcatcggcatcctggagctgcaccggcactggggc
aaagaggccttctgcctgagccaccaggaggttgcgacagcaaaccttgcctgggcttct
gtggccatccaccaggtgcaggtgtgcagaggcctggccaagcagactgagctgaacgac
ttcctgctcgatgtctccaagacgtattttgataacatagtcgcaatagattctctactt
gaacacataatgatatatgcaaaaaacctggtgaatgcagaccgctgtgcacttttccag
gtggaccataagaacaaggagctgtattcggacctttttgatattggggaggagaaggaa
ggaaagcctgtcttcaagaagaccaaagagatcaggttttccatcgagaaaggcattgcc
ggtcaggtggcgaggacgggggaagtgctgaacataccagacgcctacgcggacccacgc
ttcaacagagaagtggacctgtacacgggctacaccacccggaacatcctgtgcatgccc
atcgtgagccgcggcagcgtgatcggcgtggtgcagatggtgaacaaaatcagcggcagt
gccttctccaaaacggacgagaacaacttcaagatgtttgccgtcttctgtgctttagcc
ttacactgtgccaatatgtaccatcggattcgccactcagagtgcatctaccgggtcacc
atggagaagctgtcctaccacagcatctgcaccgcggaggagtggcagggcctcatgcgc
ttcacgctgcccgggcggctctgcaaggagatcgagctgttccactttgacatcggtcct
tttgagaacatgtggcctggcatctttgtctacatggtccaccgctcctgtgggacatcc
tgctttgagctggaaaagctgtgtcgcttcatcatgtctgtgaagaagaactaccgacgc
gtcccgtaccacaactggaagcacgcggtgaccgtggcgcactgcatgtactccatcctc
cagaacaactgcgggctcttcaccgacctggagcgcaaagggctgctgattgcttgtctg
tgtcacgacctggaccacaggggcttcagtaacagctacctgcagaagttcgaccacccg
ctcgccgccctctactccacgtccaccatggagcagcaccacttctcccagacggtgtcc
atcctgcagctggaagggcacaacatcttctccaccctgagctccagcgagtacgaacag
gtgcttgagatcatccgcaaagccatcatcgccaccgacctcgctctctacttcgggaac
cggaagcagctagaggagatgtaccagaccgggtcgctgaaccttaataaccaatcacac
agggaccgcgtcattggcttgatgatgaccgcctgcgacctctgctctgtgacgaagctg
tggccagtcacgaagttgacggcaaatgacatatatgcagaattctgggctgagggcgac
gagatgaagaagctggggatccagcctatccccatgatggacagggacaagaaggacgaa
gtcccccaaggccagctcggcttctacaacgctgtggccatcccctgctacaccaccctc
atgcagatcttcccgcccacggagcctctgctccgcgcctgcaggaacaacctcagccag
tgggagaaggtgatccgcggggaggagagcccagtgtggctgacttcccagccggcggcc
cccggcccctcggagacgctgcccgtcaagatcgatgactga

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