Desmodus rotundus (common vampire bat): 112300421
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Entry
112300421 CDS
T05907
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro01521
EGFR tyrosine kinase inhibitor resistance
dro04010
MAPK signaling pathway
dro04014
Ras signaling pathway
dro04015
Rap1 signaling pathway
dro04020
Calcium signaling pathway
dro04151
PI3K-Akt signaling pathway
dro04360
Axon guidance
dro04510
Focal adhesion
dro04520
Adherens junction
dro05100
Bacterial invasion of epithelial cells
dro05144
Malaria
dro05200
Pathways in cancer
dro05202
Transcriptional misregulation in cancer
dro05205
Proteoglycans in cancer
dro05206
MicroRNAs in cancer
dro05208
Chemical carcinogenesis - reactive oxygen species
dro05211
Renal cell carcinoma
dro05218
Melanoma
dro05223
Non-small cell lung cancer
dro05225
Hepatocellular carcinoma
dro05226
Gastric cancer
dro05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112300421 (MET)
04014 Ras signaling pathway
112300421 (MET)
04015 Rap1 signaling pathway
112300421 (MET)
04020 Calcium signaling pathway
112300421 (MET)
04151 PI3K-Akt signaling pathway
112300421 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
112300421 (MET)
04520 Adherens junction
112300421 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
112300421 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112300421 (MET)
05202 Transcriptional misregulation in cancer
112300421 (MET)
05206 MicroRNAs in cancer
112300421 (MET)
05205 Proteoglycans in cancer
112300421 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
112300421 (MET)
05230 Central carbon metabolism in cancer
112300421 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112300421 (MET)
05226 Gastric cancer
112300421 (MET)
05218 Melanoma
112300421 (MET)
05211 Renal cell carcinoma
112300421 (MET)
05223 Non-small cell lung cancer
112300421 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
112300421 (MET)
09174 Infectious disease: parasitic
05144 Malaria
112300421 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112300421 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dro01001
]
112300421 (MET)
Enzymes [BR:
dro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112300421 (MET)
Protein kinases [BR:
dro01001
]
Receptor tyrosine kinases (RTK)
MET family
112300421 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
Motif
Other DBs
NCBI-GeneID:
112300421
NCBI-ProteinID:
XP_024411541
LinkDB
All DBs
Position
Unknown
AA seq
1382 aa
AA seq
DB search
MKAPAGLAPGILVLLFTLVQKSDGECKEALVKSEMNVDMKYQLPNFTAETLIQNVVLHKH
HIYVGAINYIYVLNDKDLQKVAEYRTGPMLEHPDCFPCQNCSHKANFSGGIWKDNINMAL
LVDTYYDDQLISCGSVWRGTCQRHVLPRYNTADIQSKVHCMYSPQADEEPSQCPDCVVSA
LGTKVLMSEKHRFINFFVGNTINSSYLPDYSIHSISVRRLKETQDGFKFLTDQSYIDVLP
EFQDSYPIKYIHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSPRQEVFNILQAAYVSKPGAHLARQIGANLNDDILYGVFAQSKPDSAEPMKR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVHSDEYRTE
FTTALQRVDLFMGQFNQVLLTSITTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSPEAVVAQPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCG
WCHDKCVRLEKCPSGAWTQEICHPTIYEVFPASAPLEGGTTLTICGWDFGFRRNSKFDLK
KTRILLGNESCTLTLSESTTNMLKCTVAPAVNEHFNMSIIISSDRGTAQYSTFSYVDPII
TSISPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCALKSVSDSTLECYTPAQTTPTE
FPVKLKIDLANRETDSFSYQEDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMVINV
HEVGRNFTVACRHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVVISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSHSEAILCTVPND
LLKLNSELNIEWKQAVSSTVLGKVIVQPDQNFTGLIVGVVTISVILLLLLGLFLWLKRRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEEQFPNSSQNG
SCRQMQYPLMDLSPILTGGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLENDDKKIHCAVKSLNRITDLGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISTIFSTFIGEHYVHVNATYVNVKCVSPYPSLLSSQDKVDGEG
DT
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccctgctgggcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagtgatggggagtgcaaggaggcactagtaaaatctgaaatgaatgtggacatgaag
tatcagcttcctaacttcactgcagaaacactcatccagaatgttgttttacacaagcat
cacatttatgtcggggccattaattatatttatgttttaaatgacaaagaccttcagaag
gttgctgagtacaggactggacctatgctggaacacccagattgtttcccatgtcagaac
tgcagccacaaagccaatttttcaggtggtatttggaaagataatatcaacatggctctg
cttgttgacacatactatgatgatcaactcattagctgtggaagtgtctggagagggacc
tgccagcgacatgtccttcctcgctacaatactgctgacatacagtcgaaagtacattgc
atgtactccccacaggcagatgaagagcccagccagtgtcctgactgtgtagtgagtgcc
ctgggaaccaaggtcctgatgtctgaaaagcaccggttcatcaacttctttgtgggcaat
accataaattcttcttaccttccagattattcaatacattcgatatcagtgagaaggcta
aaggaaacacaagatggttttaagtttttgacagatcagtcctatattgatgttttacct
gaattccaagattcttaccctattaagtatatccacgcctttgaaagcaaccattttatt
tacttcttgacagtccaacgggaaactcttgatgctcagacttttcacacaagaataatc
aggttctgttctgtagactctggattgcattcttacatggaaatgcctctggagtgtatt
ctcacagaaaaaagaagaaagagatcaccaaggcaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggcccatctcgctaggcaaataggtgccaacctgaatgat
gacattctgtatggggtgtttgcacaaagcaagccagattctgctgaaccaatgaaacgc
tctgctgtctgtgcattccctatcaagtatgtcaatgaattcttcaacaagatcgtcaac
aaaaacaatgtgagatgtctccagcacttttatggacccaaccatgaacactgctttaat
cggacacttttgagaaattcatcaggttgtgaagtacacagtgatgaatatcgaacggag
tttaccacagctttgcagcgtgttgacttattcatgggccaattcaaccaagtcctctta
acatctataaccaccttcattaaaggagacctcaccatcgctaatctggggacttcagag
ggtcgctttatgcaggttgtagtttctcgatcaggatcatcaacccctcacgtgaacttt
cgcctggattcccaccctgtgtctccagaagccgtggtggcacagccattaaaccaaaat
ggctacacactggttgtcacggggaagaagatcaccaagatccctctgaacggcctgggc
tgtgaacatttccagtcctgcagtcagtgcctctctgcccctccctttgtacagtgtggc
tggtgccatgacaaatgtgtaagattggagaaatgccccagtggagcatggactcaagag
atttgtcatcctacaatctatgaggttttcccagctagtgcccctctggaaggagggaca
acattgaccatatgcggctgggactttggattcaggaggaatagtaaatttgatttaaag
aaaaccagaattctccttggaaatgagagctgcaccttgaccttaagtgaaagtacaaca
aatatgttaaaatgcacagttgctcctgcagtgaatgagcatttcaatatgtccataatt
atttcaagtgatcgagggacagcgcaatatagtacattttcttatgtggatcctataata
acaagtatttctccaagttatggtcctaagactggtggcactttacttactttaactgga
aagtacctaaatagtgggaactctagacacatttcaattggtggaaaaacctgtgcttta
aaaagtgtgtcagatagtactcttgaatgttataccccagcccaaaccactccaactgag
tttcctgttaagttgaaaattgacttagccaaccgagagactgacagcttcagttaccag
gaagaccctattgtctatgaaattcatccaaccaaatcttttattagtggtgggagcaca
ataacaggtgttggaaaaaacctgaattcagttagtgtcctaaggatggtaataaatgtg
catgaagtaggaaggaacttcacagtggcatgtcgacatcgctctaattcagagataatc
tgctgtactactccttcactacagcagctgaatctgcaactccccctgaaaactaaagcc
tttttcatgttagatgggatccattccaaatacttcgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtggtgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgacattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagactatatactcacattctgaagctattttatgtacggtccccaatgac
ctgctgaaattgaacagtgagctaaatatagagtggaagcaagcagtttcttcaactgtc
cttggaaaagtaatagttcaaccagatcagaatttcacaggattgattgttggtgttgtc
acaatatctgtaatactcttgttattacttgggcttttcctgtggctgaaaaggagaaag
caaattaaagatctgggcagcgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactaccgagctacttttccagaagagcagtttcctaactcatctcagaatggg
tcatgcagacaaatgcagtatcctctgatggacctgtccccaatcctgactggtggggac
tctgatatatccagtccattactgcaaaataccgtccacattgacctcagtgctctaaat
ccagagctggttcaggcagtccagcacgtagtgattgggcctagtagcctgattgtgcat
ttcaatgaagtcataggaagaggtcattttgggtgcgtataccatgggactttgttggaa
aatgatgacaagaaaattcattgtgctgtgaaatccttgaatagaatcactgacctagga
gaagtttcccaatttctgactgagggaatcatcatgaaagattttagtcatcccaatgtt
ctctcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccgtac
atgaaacatggagatcttcgaaatttcattagaaatgagactcataacccaactgtgaaa
gatcttattggttttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgttcacagagacttggcagcaagaaactgtatgctggatgaaaaattcactgtcaaa
gttgctgattttggtcttgccagagacatgtatgataaagaatactacagtgtacacaat
aaaacaggagcaaaactgccagtaaagtggatggctttagaaagtctacaaactcagaag
tttaccaccaagtcagatgtgtggtcctttggtgtgctcctctgggagctgatgacaaga
ggagcaccaccttatcctgatgtcaacacctttgatataacagtttacttgttgcaaggc
cgaaggctcttacaacctgaatactgcccagatcccttatatgaagtgatgctaaaatgc
tggcaccccaaagccgaacttcgcccatccttttcagaactggtctccaggatatcaacg
atattctctactttcattggggagcactacgtccatgtgaatgctacttatgtgaatgtc
aaatgtgtctctccatacccttctctgttgtcatcacaagataaagttgatggcgaggga
gacacatga
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integrated database retrieval system