Desmodus rotundus (common vampire bat): 112300725
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Entry
112300725 CDS
T05907
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00562
Inositol phosphate metabolism
dro01100
Metabolic pathways
dro01521
EGFR tyrosine kinase inhibitor resistance
dro04012
ErbB signaling pathway
dro04014
Ras signaling pathway
dro04020
Calcium signaling pathway
dro04062
Chemokine signaling pathway
dro04064
NF-kappa B signaling pathway
dro04066
HIF-1 signaling pathway
dro04070
Phosphatidylinositol signaling system
dro04072
Phospholipase D signaling pathway
dro04360
Axon guidance
dro04370
VEGF signaling pathway
dro04380
Osteoclast differentiation
dro04611
Platelet activation
dro04613
Neutrophil extracellular trap formation
dro04625
C-type lectin receptor signaling pathway
dro04650
Natural killer cell mediated cytotoxicity
dro04662
B cell receptor signaling pathway
dro04664
Fc epsilon RI signaling pathway
dro04666
Fc gamma R-mediated phagocytosis
dro04670
Leukocyte transendothelial migration
dro04722
Neurotrophin signaling pathway
dro04750
Inflammatory mediator regulation of TRP channels
dro04919
Thyroid hormone signaling pathway
dro04933
AGE-RAGE signaling pathway in diabetic complications
dro04935
Growth hormone synthesis, secretion and action
dro05167
Kaposi sarcoma-associated herpesvirus infection
dro05169
Epstein-Barr virus infection
dro05170
Human immunodeficiency virus 1 infection
dro05171
Coronavirus disease - COVID-19
dro05200
Pathways in cancer
dro05205
Proteoglycans in cancer
dro05206
MicroRNAs in cancer
dro05214
Glioma
dro05223
Non-small cell lung cancer
dro05225
Hepatocellular carcinoma
Module
dro_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112300725 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
112300725 (PLCG2)
04014 Ras signaling pathway
112300725 (PLCG2)
04370 VEGF signaling pathway
112300725 (PLCG2)
04064 NF-kappa B signaling pathway
112300725 (PLCG2)
04066 HIF-1 signaling pathway
112300725 (PLCG2)
04020 Calcium signaling pathway
112300725 (PLCG2)
04070 Phosphatidylinositol signaling system
112300725 (PLCG2)
04072 Phospholipase D signaling pathway
112300725 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112300725 (PLCG2)
04613 Neutrophil extracellular trap formation
112300725 (PLCG2)
04625 C-type lectin receptor signaling pathway
112300725 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
112300725 (PLCG2)
04662 B cell receptor signaling pathway
112300725 (PLCG2)
04664 Fc epsilon RI signaling pathway
112300725 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
112300725 (PLCG2)
04670 Leukocyte transendothelial migration
112300725 (PLCG2)
04062 Chemokine signaling pathway
112300725 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
112300725 (PLCG2)
04919 Thyroid hormone signaling pathway
112300725 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
112300725 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112300725 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
112300725 (PLCG2)
04380 Osteoclast differentiation
112300725 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112300725 (PLCG2)
05206 MicroRNAs in cancer
112300725 (PLCG2)
05205 Proteoglycans in cancer
112300725 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112300725 (PLCG2)
05214 Glioma
112300725 (PLCG2)
05223 Non-small cell lung cancer
112300725 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112300725 (PLCG2)
05171 Coronavirus disease - COVID-19
112300725 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
112300725 (PLCG2)
05169 Epstein-Barr virus infection
112300725 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112300725 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112300725 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dro04131
]
112300725 (PLCG2)
Enzymes [BR:
dro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
112300725 (PLCG2)
Membrane trafficking [BR:
dro04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
112300725 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
112300725 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
PH
SH3_9
PH_12
EF-hand_PLCG1
SH2_1
PH_14
SH3_2
EF-hand_like
Adhesin_E
GDPD
Motif
Other DBs
NCBI-GeneID:
112300725
NCBI-ProteinID:
XP_024411812
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MTTMVNVDGLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKCSKDFERAKAVRQKEDCCFTILYGTQFTLSTLSLAADSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFLEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNRVRKRMTKFIDDTMRETAEPFLFVDEFLMYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVVLSIEEHCGVEQQRYMARV
FKEVFGDMLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDTPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCSETGGKDGTFLVRESERFPNDYTLSFWRSGRVQHCRIRSTMEDGVMKYY
LTDNLMFPSIYALIQYYRGTHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGSDSYAITFRAKGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
KKHALYRKMKLRYPVTPDLLERYSMERDINSLYDVSRMYVDPSEISPSMPQRTVKALYDY
KAKQSDELSFYRGALIHNVSKEPGGWWKGDYGTKIQQYFPSNYVEDISSVDVEDLEKQII
EDNPLGSLCRGILDLNAYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIRQITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVVRQKPIDLLKYNQKALTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNQALFSLNGRTGYVLQPESMRTDKYDPMPPESQRKIQMTLTVKVLGARHLPKPGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALIKEFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatggtcaatgtggatggccttccggagtatgagaagagtcagatcaagaga
gccctggagctgggcacagtgatgaccgtgttcagcttccgcaagtccaccccggagcgc
aggactgtgcaggtgatcatggagacgcggcaggtggcctggagtaagacagccgacaag
atcgaaggctttttggatatcatggaaataaaggaaatccgcccggggaagtgctccaag
gattttgagcgtgcaaaagcagtccgccagaaggaagactgctgcttcaccatcctgtac
ggcacccagttcaccctcagcacactcagtttagcagctgactccaaggaagatgcaacc
aagtggctctctggcttgaaaatcttacaccaagaagcaatgagtgcatccacacccacc
attattgagagttggctgagaaagcagatttattcagtggaccaaaccagaagaaacagc
atcagcctccgagagctgaagaccatcttgcccctggtcaacttcaaagtgagcagtgcc
aagttcctcaaggataagtttttggaaataggcgcgcacaaagacgaactcagctttgaa
cagttccatctcttctataaaaaacttatgtttgaacagcaaaagtcgattctcgacgaa
ttcaaaaaagactcctccgtgttcatcttggggaacactgaccggccggatgcctccgct
gttcacctgcacgatttccagcggtttctcttacatgagcagcaggagctctgggctcag
gatctgaacagagtccgcaagaggatgactaagtttatcgacgacacgatgagggaaact
gcggagcccttcctatttgttgatgagttcctcatgtacctgttttcacgggagaacagc
atttgggatgagaagtatgacgtggtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcctcatcacataacacgtacctcacaggtgaccagctgcggagtgagtcg
tccacggaggcatacatccgctgtctgcgcatgggctgtcgctgcattgagttggactgc
tgggatgggcctgacgggaagcccatcatctaccacggctggacacggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaagaccatgcctttgtcacctcgagcttcccc
gtggtcctgtccatcgaggagcactgtggcgtggaacagcagcgctacatggccagagtg
tttaaggaggtgtttggcgacatgctgctgatgaagcccacggaggccagtgccgaccag
ctgccctcacccagccagctgcgggaaaagatcatcatcaagcacaagaagctgggcccc
cgaggcgacgtagatgtcaacgtggaggacaagaaagatgagcacaagcaacagggcgaa
ctgtacatgtgggactccatcgaccagaaatggactcggcactactgcgccatcgccgat
gccaagctgtccttcagcgatgacattgaacagaccatggaagaggaagtgccccaggat
acgcctcccaccgagctgcattttggagagaagtggtttcataagaaggtggagaagagg
acgagtgctgagaagctgctgcaggaatactgctctgagacggggggcaaggacggaacc
ttcttggtgcgggagagcgagaggttccccaatgactacaccctgtccttctggcggtca
ggccgggtccagcactgccggatccgctccaccatggaggacggggtcatgaagtattac
ctgactgacaacctcatgttccccagcatctacgccctcatccagtactaccgcgggacg
cacctgcgctgcgccgagttcgagcttcggctcactgaccctgtgcccaaccccaacccc
catgagtcaaaaccgtggtactatgacgggctgagccgtggagaagcggaggacatgctg
atgagagttccccgggacggcgccttcctcatccggaagcgggaaggcagcgactcctac
gccatcaccttcagggccaagggcaaggtgaagcactgtcgcatcaaccgggacggccgg
cacttcgtgctggggacctccgcctacttcgagagtctggtggagctcgtcagttactac
aagaagcatgcgctgtaccgaaagatgaagctgcgctaccccgtgactcccgatctcctg
gagcgctacagtatggaaagagacataaactccctgtatgatgtcagcagaatgtatgtg
gatcccagtgagatcagtccttctatgcctcagagaactgtgaaagctctgtatgactac
aaagccaagcagagtgatgagctgagcttctaccgtggcgccctcattcacaacgtctcc
aaggagcctgggggctggtggaaaggagactatggaaccaaaatccagcagtacttcccg
tccaattacgttgaggacatttcatcggttgatgtggaggatctggagaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatactggatctcaatgcctataatgtt
gtgaaagccccacaggggaaaaaccagaagcctttcgtctttatcctggagcccaagaag
cagggggaccctccggtggagtttgccacagacagggtggaagagctctttgaatggttt
cagagcatccggcagatcacctggaagattgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtcgatcgccatcgagctctcggacctggtcgtgtactgcaaaccaacc
agcaagaccaaagacaacttagaaaatcccgacttccgagaaatccgttcctttgtggag
acgaaggctgacagcgtcgtcaggcagaaacccatcgatctcctgaagtacaatcagaag
gccctgacccgcgtttacccgaagggacagagggtggattcctccaactacgatcccttc
cgtctctggctgtgtggctcccaaatggtggcactcaattttcagactgcggacaagtac
atgcagatgaatcaggccttgttctcactcaatgggaggaccggctacgtcctacagccc
gagagcatgaggacagataagtacgaccccatgccacccgagtcccagaggaagattcag
atgaccttgacggtcaaggttctcggggctcgccatcttcccaagcctggacggagcatt
gcatgtccctttgtggaggtggaaatatgtggagctgaatatgacaacaacaagtttaag
acgacggttgtgaatgacaatggcctaagccctgtttgggctccaacacaggagaaggtg
acatttgaaatttatgatccaaacctcgcgtttctgcgctttgtggtgtatgaggaagat
atgttcagcgaccccaactttctcgctcatgctacataccccattaaaggaatcaaatca
ggatttagatctgttcctctgaagaatgggtacagcgaagacattgagctggcctccctc
ctggttttctgtgagatgcggccagtgctggagagcgaagaggaactgtactcctcctgt
cgccagctgcggaggcggcaagaggagctgaacaaccagctctttctatatgacacgcac
cagaacctgcgcaatgccaaccgggatgccctcattaaagaattcaatgtcaacgagaac
cagctgcagctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaac
agcaagttttactcatag
DBGET
integrated database retrieval system
