Desmodus rotundus (common vampire bat): 112301524
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Entry
112301524 CDS
T05907
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro04217
Necroptosis
dro04380
Osteoclast differentiation
dro04620
Toll-like receptor signaling pathway
dro04621
NOD-like receptor signaling pathway
dro04630
JAK-STAT signaling pathway
dro04658
Th1 and Th2 cell differentiation
dro04659
Th17 cell differentiation
dro05145
Toxoplasmosis
dro05160
Hepatitis C
dro05161
Hepatitis B
dro05162
Measles
dro05164
Influenza A
dro05165
Human papillomavirus infection
dro05167
Kaposi sarcoma-associated herpesvirus infection
dro05168
Herpes simplex virus 1 infection
dro05169
Epstein-Barr virus infection
dro05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
112301524 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
112301524 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
112301524 (TYK2)
04621 NOD-like receptor signaling pathway
112301524 (TYK2)
04658 Th1 and Th2 cell differentiation
112301524 (TYK2)
04659 Th17 cell differentiation
112301524 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
112301524 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
112301524 (TYK2)
05160 Hepatitis C
112301524 (TYK2)
05171 Coronavirus disease - COVID-19
112301524 (TYK2)
05164 Influenza A
112301524 (TYK2)
05162 Measles
112301524 (TYK2)
05168 Herpes simplex virus 1 infection
112301524 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
112301524 (TYK2)
05169 Epstein-Barr virus infection
112301524 (TYK2)
05165 Human papillomavirus infection
112301524 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112301524 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dro01001
]
112301524 (TYK2)
Enzymes [BR:
dro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112301524 (TYK2)
Protein kinases [BR:
dro01001
]
Non-receptor tyrosine kinases
JAK family [OT]
112301524 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
112301524
NCBI-ProteinID:
XP_024412779
LinkDB
All DBs
Position
Unknown
AA seq
1191 aa
AA seq
DB search
MGSPFPAKPAVKTMPLCHWGGTTRGSKPDGDEAQLMTTRGSLKVLLHWAGPDSKEPWVTF
SEATLTAEEVCIHIAQKVGITPPCFNLFALFDAQAQVWLPPNHILEVSRDTNLTLHFRMR
FYFRNWHGTNPHEPAVYRCGPPGAETSSEQAEQGVQLLDSASFEYLFEQGKHEFVNDVAS
LWELSSEEEIHHFKNESLGMAFLHLCHLALCRGTSLEKVAKKISFKDCIPRSFREEIQQY
NVFTQLRLWIIFRRFLQAFQPGRLSQLDIMVKYLATLERLAPRFGTERVPVCHLELVAQA
SGEHCYIWDSGHAPVDPQPESAVESPTHEVLVTGTGGIQWRPVKTEGPDRSRSPRAGLSG
KKAKAQELGDQPVDRPQEAPWAYFCDFQDITHVVLREHHASIHCQDKCLELTLPSRAIAL
SLVSLVDGYFRLTADSNHYLCHEVAPPRLVMSIQDGIHGPLLEPYVLAKLQPEGGLYLIH
WSTSHFNRLILTVAQRDQAPGMQCLRLRKFPIELSAGAFSLESWDRSFPSVRELRAALQG
CSLQAGDNCFSLRHCCLPRPGEISNLTITRGPRASTRSLNLSQLSFHRICQDDITQLYHL
GQGTRTNVYEGLLRVGGGSPEEDKADGGDPTSLGEDHGQELRVVLKVLDPSHHDIALAFY
ETASLMSQVSHVHLTFVHGICVHSSKNIMVTEFVEHGPLDVWLRRERGRVPVAWKVAVAQ
QLASALSYLEDKSLAHGNVCGRNILLARVGLAEGTSPFIKLSDPGVGLGALSREERVERI
PWMAPECMSGGANSLSTAADKWGFGATLLEICFDGEAPLQDRSPSEKECFYQKQHQLPEP
ACPELATLTSQCLTYEPAQRPSFRTILRDLTHLQLQNLSAVLHVNPTSLASDPTIFHKRY
LKKIRDLGEGHFGKVSLYCYDPTNEGTGEMVAVKALKGGCGPQLHTGWRREIDILRTLYH
EHIVKYKGCCEDQGEKMVHLVMEYMPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHE
QHYVHRDLAARNVLLDNDSLVKIGDFGLTKAVPEGQEYYRVREDGDSPVFWYAPECLKEY
KFYYASDVWSFGVTLYELLTYCDSSQSPPSKFIELIGPTQGQLTVLRLTELLERGERLPR
PEKCPYEIYVLMKNCWEAEASFRPTFQNLIPILKTAHEKYWGQASSVFNVC
NT seq
3576 nt
NT seq
+upstream
nt +downstream
nt
atgggctctcccttcccagccaagccagctgtcaagaccatgcctctgtgccattggggg
ggcaccaccaggggcagcaagcccgatggggatgaagctcagctcatgaccaccagagga
agcctgaaggtgctcctgcactgggctggccccgacagcaaggagccctgggtcactttc
agtgaggccacactgaccgcagaggaggtctgcattcacattgcacaaaaagtcggcatc
actccgccctgcttcaatctctttgccctctttgatgcccaggcccaggtctggctgccc
ccaaaccacattctggaggtctccagagacacaaacttgaccttgcacttccgcatgagg
ttttatttccggaactggcatggcacgaatcctcacgagccagccgtgtaccgctgcgga
cccccaggggccgagacctcatcagaacaggcagaacagggggtgcaactcctggactca
gcctcctttgagtacctctttgagcagggtaaacatgagtttgtgaatgatgtggcatcg
ctatgggagctgtcgagtgaggaggagatccaccactttaagaacgagagcctaggcatg
gcctttctgcacctctgccacctcgctctctgccgcggtacttccctggagaaggtggcc
aagaagatcagcttcaaagactgtatcccacgctccttccgggaggagatccagcaatac
aacgtgttcacacagctacgcctgtggatcatcttccgcaggttcctgcaggccttccag
ccgggccgcctttcccagctggacatcatggtcaagtacctggccacactcgagcggctg
gcaccccgcttcggcacagagcgtgtgcctgtgtgccacctagagctggtagctcaggcc
tcgggggagcactgctacatctgggacagtgggcacgcccctgtggacccccagcccgag
tccgcagtcgaatcccccacccatgaggtgctggtgactggcactggtggcatccagtgg
cggccagtaaagacagagggccccgacagaagcaggagtcctcgtgctggcttatctggg
aagaaagccaaggcccaagagttgggtgaccagcctgtggacaggccacaggaggcaccg
tgggcctacttctgtgacttccaggacatcacccatgtggtgctaagggaacaccatgcc
agcatccactgccaggacaagtgcctggagctgaccctgccttcccgggccatcgccctg
tccttggtgtcactggtggatggctacttccgcctgacggccgactcaaaccactacctg
tgccacgaggtggctcctccacggctggtgatgagtatccaggacggcatccacggaccc
ctgctggagccatacgtgctggccaagcttcagccagagggtggcctttatctcatccac
tggagcaccagccacttcaaccgcctcatcctcacggtggcccagcgggaccaggcccct
ggcatgcagtgtttgcgtctgcgcaagttccccattgagctgtctgcaggggccttcagc
ctggagagctgggaccggtcctttcccagcgtgcgggagctgcgggccgccctgcagggc
tgctctctgcaggctggtgacaactgcttctccctgcgccactgctgcctgccgaggcca
ggagagatctccaacctcaccattacgcgggggcctcgagccagcaccaggtctctcaac
ctcagccagctcagcttccaccggatctgccaggatgacatcacccagctgtaccacttg
ggccagggcacaaggaccaatgtgtatgagggcctcttacgagttgggggcggaagccct
gaggaagacaaggcagacggtggggaccccacctcacttggcgaggaccatgggcaggag
ctacgagtggtgctgaaggtgctggaccccagtcaccatgacatcgccctggccttctat
gagacagccagcctcatgagccaggtgtcccatgtgcacctgacctttgtccacggtatc
tgcgtgcacagctccaaaaatatcatggtgacagagttcgtggaacatggacccctggac
gtgtggctgcggcgggagaggggccgtgtgcctgtggcctggaaggtggcagtggcccag
cagctggccagtgccctcagctacctggaggacaagagcctggctcacggtaacgtgtgt
ggccggaacatcctgctggcacgtgtggggctggcagagggcaccagcccgttcatcaaa
ctgagcgaccctggcgtgggcctgggtgccctttccagggaggagcgagtagagcggatc
ccctggatggcccccgagtgcatgtctggtggagccaacagcctgagcactgctgctgac
aagtggggcttcggtgccaccctcctggagatctgcttcgacggggaggctcccctgcag
gaccgcagtccctccgagaaagagtgtttctaccagaagcagcaccaactgcctgaacct
gcgtgcccggagctagccacactcaccagccagtgcctgacctatgagccagcccagcgg
ccctccttccgcaccatccttcgtgaccttactcaccttcagctccaaaatctttctgca
gtcctgcatgtgaacccaacctcactggcatcagaccccactattttccacaagcgctat
ttgaaaaagatccgggatctgggtgagggtcacttcggcaaggtcagcctgtactgctat
gacccgaccaacgaaggcactggtgagatggtggccgtgaaggctctcaaggggggctgc
ggccctcagctccacactggctggaggcgggagattgacatcctgcgcacactctaccat
gaacacattgtcaagtacaagggctgctgtgaggaccaaggtgagaaaatggtgcacctc
gtcatggagtacatgcccctgggcagcctccgagactacctgcctcggcacagcataggg
ctggcccagctgctgctgttcgcacagcagatctgcgagggcatggcctacctgcacgag
cagcactatgtccaccgagacctggctgcccgcaacgtgctgctggacaacgacagcctg
gtcaagattggggactttggcctcaccaaggctgtgcctgaaggccaagagtactaccgc
gtgcgcgaggatggggacagccctgtgttctggtatgcccccgagtgcctgaaggagtat
aagttctactatgcatccgatgtctggtcctttggagtcaccctgtatgaactgctgacc
tactgtgactccagccagagccccccctcgaaattcatcgagctcataggccccacccag
gggcagctaacagtactgaggctcactgagctgctggaacgtggggagaggctgccacgg
ccagagaaatgtccctatgagatctatgtcctcatgaagaactgctgggaggcagaggcc
tcatttcgcccaaccttccagaacctcatacccatcctgaaaacggcccatgagaaatac
tggggccaggcctcctcggtgttcaatgtctgctga
DBGET
integrated database retrieval system
