Desmodus rotundus (common vampire bat): 112305577
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Entry
112305577 CDS
T05907
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00230
Purine metabolism
dro00670
One carbon pool by folate
dro01100
Metabolic pathways
dro01523
Antifolate resistance
Module
dro_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112305577 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112305577 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112305577 (GART)
Enzymes [BR:
dro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
112305577 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
112305577 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
112305577 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
Sacchrp_dh_NADP
STING_LBD
Motif
Other DBs
NCBI-GeneID:
112305577
NCBI-ProteinID:
XP_024417137
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSNHVKQVLVAPGNAGTACSKKISNAAISLSDHSALAE
FCKDENIEFVVVGPEAPLAAGIVRNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTDPEEACSFIMSADFPALVVKASGLAAGKGVTVASSREDACGAVRQIMQDKTF
GAAGETVVIEELLEGEEVSCLCFTDGRTVAAMPPAQDHKRLLEGDRGPNTGGMGAYCPVP
QVSKDLLLKIKNAILQRTVDGMQQEGVPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCASLPVWLEDRAAITVVMASQGYPGDYAKGAEITGFAEA
QALGLVVFHAGTALKDGKVVTNGGRVLAVTAIRENLVWALEEARKGLAAIKFEGAVYRKD
VGHGAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLCDLR
AAGFKDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLGTAEAVVAGIAKACVQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQQLP
CLERIAEGDVVIGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGSQTLGDLLLTPTK
IYSQSLLPVLRSGRVNAFAHITGGGLLENIPRVLPQKFGVDLDAHAWRIPTVFSWLQQQG
RLSEEEMARTFNCGVGAALVVPADLAAQVLRDIQQLQEEAWVIGRVVACPEGRPRVRVRH
LMEAMRVDGPVLKNGAANSAFSVQPKRARVAVLISGTGSNLQALIDSTQEPGSAARIVVV
ISNKAAVAGLDRAARAGIPTRVINHKLYKSREEFDTAVDQVLEEFSTDLVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFRGSNAHEQALGAGVTVTGCTVHFVAEEVDAGQIILQEA
VPVKRGDTVASLSERVKLAEHRIFPAALQLVASGTVQLGEDGKLCYVQED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtgattggcagtggagggagagagcacacgctggcctggaaa
ctggcacagtctaatcatgtcaaacaggtgttggttgcgccaggaaatgcaggaactgcc
tgctccaaaaagatttcaaatgctgccatctccctcagcgaccacagtgccctggccgag
ttctgcaaagatgagaatattgaatttgtcgttgttggaccggaggcacccctggctgcc
ggaatcgtcaggaacctgacgtccgcaggagtgcgctgctttggccccacagcagaagca
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacaggcacggaatccca
actgcccggtggagagctttcaccgatcccgaagaggcctgcagcttcatcatgagtgca
gacttcccggccttggtggtaaaggccagcggcctcgcagctgggaaaggggtgactgtc
gcttcgagcagagaagacgcctgcggagcggtccggcagatcatgcaggataaaactttt
ggagcagctggagaaactgttgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgacgggaggactgtggcggccatgcccccagctcaggaccataagcga
ctgctggaaggagaccgaggccccaacacgggggggatgggcgcctattgtccagtgcct
caggtttctaaggatttgttgctaaaaattaaaaatgccattcttcagaggacagtggat
ggcatgcagcaggagggtgtgccgtacacaggtgtcctctatgctggcataatgctgacc
aaggatggcccaaaggttctggagtttaattgccgtttcggtgatccagagtgccaagta
atcctcccacttctgaaaagcgatctgtatgaagtgattcagtctaccctggacggcctg
ctctgcgcctctctgcctgtctggcttgaagaccgtgcagctatcactgttgtcatggca
agtcagggttacccaggagactacgccaagggcgcagagataacagggtttgctgaggcc
caggctttggggctggtggtgttccacgcaggcacagccctaaaagatggcaaggtggtg
accaatggagggagagtccttgcagtgacagccatccgggaaaatctcgtctgggccctt
gaagaagccaggaaaggactggctgcgatcaagttcgagggcgctgtttacaggaaggac
gtaggccacggagccatagcgttcctccagcagcccaggggcctgacttacaaggagtct
ggggtagatattgcagctggaaatatgctggtcaagaaaattaaacctttagccaaagcc
acctccagaccaggctgtgatgttgatcttggcggttttgctggtctttgtgatttgcga
gcagccggtttcaaagatcctctgctggcctgtggaacagatggcgttggaacgaaactg
aagattgcccagcagtgcaataaacatgataccattggccaagacttggttgctatgtgt
gtaaatgacattctggcacaaggagcagagcccctcttcttcctcgattacttttcctgt
gggaaactcgacctcggcaccgcggaagctgttgtggctggaatcgccaaagcgtgtgtg
caagctgggtgtgcgctcctcgggggtgagacagcagaaatgccagacatgtaccctcct
ggagaatatgacctggccggttttgccgtcggcgccatggagcgggaccagcagctcccc
tgcctggaaaggatcgcagaaggggatgtggttattggggtggcgtcatccggtcttcac
agcaatggatttagcctcgtgaggaaaatcgtagcgaagtcttcccttcagtactcctcc
ccagcacctgacggctgtggcagccagaccttaggggacttacttctaactccaaccaaa
atctacagccagtcactgttacctgtcttacgttcaggacgcgtcaatgcctttgcccac
atcacgggtggaggactgctggaaaacatccccagagtcctccctcagaaattcggggtc
gatttagatgcccacgcctggaggatccccacggtcttctcgtggttgcagcagcaagga
cgcctctctgaggaagagatggccaggacgtttaactgtggggttggcgctgccctcgtg
gtgcctgcggacctggcagctcaggttctgagggacattcagcagctccaggaggaagcc
tgggtgattggcagggtggtggcctgccctgaaggccgtccccgggtgagggtcaggcac
ctgatggaagccatgcgtgtagacggaccggtgttgaagaacggcgcagcgaacagtgcc
ttctctgtccaaccaaaaagggcgagagtggctgtcttaatttctggaacaggatcgaac
ctccaggctctcatagacagcacccaggagccaggcagtgccgcccgcatcgtggtcgtc
atctccaacaaggccgccgtggctggcctagacagagccgcgagagcaggcattcccacc
agagtaattaatcataagttatataaaagtcgtgaagaatttgacactgcagttgaccaa
gtgcttgaagagttctccacagacttagtctgccttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatccttgctccct
tcttttcggggttcaaatgcccatgagcaagccctgggcgctggcgtcacagtaacaggg
tgcaccgtgcactttgtagctgaagaggtggatgctggacagatcatcttgcaggaagct
gttccagtgaagcggggtgacactgttgccagtctgtctgaaagagtgaagttagcagaa
cacaggatctttcccgcagccctgcagctggtggccagtgggactgtccagcttggagag
gatggcaagctctgttatgtccaggaggattga
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