Desmodus rotundus (common vampire bat): 112306076
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Entry
112306076 CDS
T05907
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro01521
EGFR tyrosine kinase inhibitor resistance
dro01522
Endocrine resistance
dro04010
MAPK signaling pathway
dro04014
Ras signaling pathway
dro04015
Rap1 signaling pathway
dro04066
HIF-1 signaling pathway
dro04068
FoxO signaling pathway
dro04081
Hormone signaling
dro04114
Oocyte meiosis
dro04140
Autophagy - animal
dro04144
Endocytosis
dro04150
mTOR signaling pathway
dro04151
PI3K-Akt signaling pathway
dro04152
AMPK signaling pathway
dro04211
Longevity regulating pathway
dro04213
Longevity regulating pathway - multiple species
dro04510
Focal adhesion
dro04520
Adherens junction
dro04550
Signaling pathways regulating pluripotency of stem cells
dro04730
Long-term depression
dro04913
Ovarian steroidogenesis
dro04914
Progesterone-mediated oocyte maturation
dro05200
Pathways in cancer
dro05202
Transcriptional misregulation in cancer
dro05205
Proteoglycans in cancer
dro05214
Glioma
dro05215
Prostate cancer
dro05218
Melanoma
dro05224
Breast cancer
dro05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112306076 (IGF1R)
04014 Ras signaling pathway
112306076 (IGF1R)
04015 Rap1 signaling pathway
112306076 (IGF1R)
04066 HIF-1 signaling pathway
112306076 (IGF1R)
04068 FoxO signaling pathway
112306076 (IGF1R)
04151 PI3K-Akt signaling pathway
112306076 (IGF1R)
04152 AMPK signaling pathway
112306076 (IGF1R)
04150 mTOR signaling pathway
112306076 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
112306076 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112306076 (IGF1R)
04140 Autophagy - animal
112306076 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
112306076 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112306076 (IGF1R)
04520 Adherens junction
112306076 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
112306076 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
112306076 (IGF1R)
04914 Progesterone-mediated oocyte maturation
112306076 (IGF1R)
09156 Nervous system
04730 Long-term depression
112306076 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
112306076 (IGF1R)
04213 Longevity regulating pathway - multiple species
112306076 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112306076 (IGF1R)
05202 Transcriptional misregulation in cancer
112306076 (IGF1R)
05205 Proteoglycans in cancer
112306076 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112306076 (IGF1R)
05214 Glioma
112306076 (IGF1R)
05218 Melanoma
112306076 (IGF1R)
05215 Prostate cancer
112306076 (IGF1R)
05224 Breast cancer
112306076 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112306076 (IGF1R)
01522 Endocrine resistance
112306076 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dro01001
]
112306076 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
dro04090
]
112306076 (IGF1R)
Enzymes [BR:
dro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112306076 (IGF1R)
Protein kinases [BR:
dro01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
112306076 (IGF1R)
CD molecules [BR:
dro04090
]
Proteins
112306076 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
112306076
NCBI-ProteinID:
XP_024417685
UniProt:
K9IQ63
LinkDB
All DBs
Position
Unknown
AA seq
1408 aa
AA seq
DB search
MKSDCGVGSLTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNVTRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNHCQKTCPSACGKRACTENSECCHPECLGSCS
APDDDAACVACRHYYHAGICVPSCPPNTYRFEGWRCVDRDFCANILNAESSSDTEGFVIH
DGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCDEEKKTKTIDSVTSAQMLQGCTIFKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLHFTSTNTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPSNKDMEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDSYLYR
HNYCSKADKIPIRKYADGTIDIEEVTENPRTEVCGGEKGPCCACPKTEAEKQAEKEEAEY
RKVFENFLHNSIFVPRPERKRRDVAQIANTTMSSRIRNSTVADIYNVTDLEELETEYPFF
ETRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPV
TWEPKPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVPRQEYRKYGGAKLNRLNP
GNYTARIQATSLSGNGSWTEPVFFYVQAKTTYENFIHLIIALPVAVLLIVGGLVIMLYVF
HRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVA
KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSLRPEIEKVPVRGRARWRLSGALCDVAGQQVPGVSTRRRLRSLQSQ
NNPAFAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRD
IYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNE
QVLRFVMEGGLLDKPDNCPDMLFELMRVCWQYNPKMRPSFLDIIGSIKDEMEPGFQEVSF
YYSDENKPPEPEELELEPDNMESVPLDPSASSYSLPLPDRYSGHKAENGPGPGVLVLRAS
FDERRPYSHMNGGRKNERALPLPQSSTC
NT seq
4227 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctgactgcggagtagggtccctgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggcccacgagtggagaaatctgcgggcctggcatcgacatccgc
aatgactaccagcagctgaagcgcctggagaactgcacggtgatcgagggttacctgcac
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggcgacctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactatgccctggtcatcttc
gagatgaccaacctcaaagacatcgggctctacaacctgaggaacgtcacgcggggggcc
atcaggatcgagaagaatgccgacctctgctacctgtccacagtggactggtcgctgatc
ctggacgcggcgtccaacaactacatcgtgggtaacaagcccccgaaggagtgcggggac
ctgtgtccggggacaatggaggagaagcccttgtgcgagaagaccaccatcaacaacgag
tacaactaccggtgctggaccacgaaccactgccagaaaacgtgcccgagcgcgtgcggg
aagcgcgcctgcacggagaacagtgagtgctgccacccagagtgcctgggcagctgcagc
gcgcccgatgacgacgcggcctgcgtggcctgccgccactactaccacgccggcatctgc
gtgcccagctgcccacccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgtgccaacatcctcaacgccgagagcagcagcgacactgagggcttcgtgatccat
gacggcgagtgcatgcaggagtgcccctccggcttcatccgcaacggcagccagagcatg
tactgcatcccttgcgaaggcccttgccccaaagtctgcgatgaagaaaagaagacgaag
accatcgattcagtgacttccgctcagatgctccaaggctgcaccatcttcaagggcaat
ttgctcattaacatccgccggggcaataacattgcctcggagctggagaacttcatgggg
ctcatcgaggtggtgacgggctacgtgaagatccgccattcccacgccttggtctccttg
tccttcctcaagaaccttcgcctgatcttgggagaggagcagctcgaggggaactactcc
ttctatgtcctcgacaaccagaacctgcagcagctgtgggactgggaccaccgcaacctg
accatcaaagcaggcaagatgtacttcgccttcaaccccaagttgtgtgtctccgaaatc
taccgcatggaggaagtgacggggaccaaagggcgccagagcaaaggggacataaatacc
aggaacaacggagagagagcctcctgtgagagcgacgtgctgcacttcacctccaccaac
acgtggaagaaccgcatcatcataacatggcaccggtaccggcccccagactacagggac
ctcatcagcttcaccgtctactacaaggaagcaccctttaaaaatgtgacggagtacgac
ggtcaggacgcgtgtggctccaacagctggaacatggtggacgtggacctcccctccaac
aaggacatggagcctggcatcttgctgcacgggctgaagccctggacgcagtacgcggtg
tacgtgaaggccgtgaccctcaccatggtggagaacgaccacatccgcggggccaagagt
gagatcctgtacattcgcaccaatgcctcagttccttccatccccctggatgttctctcg
gcgtcgaactcctcttcgcagctgatcgtgaagtggaacccgccgtctctgcccaatggc
aacctgagctactacattgtcaggtggcagcaacagccccaggacagctacctgtaccgg
cacaattactgctccaaagcagacaaaatccccatccggaagtatgctgacggcaccatc
gacatcgaggaggtgacagagaaccccaggaccgaagtgtgtgggggagagaaggggcct
tgctgcgcctgtcccaagaccgaggcagagaagcaggccgagaaggaggaggccgagtac
cgcaaagtctttgagaacttcctgcacaactccatcttcgtgcccagacctgaaaggaag
cggagagatgttgcgcaaattgccaacaccaccatgtccagtcggattcggaacagcacg
gtggcggacatctacaacgtcacagacctggaggagctggagacggagtaccctttcttc
gagaccagagtggacaacaaggagagaactgtcatttctaacctccggcctttcaccctg
taccgcattgatatccacagctgcaaccatgaggccgagaagctgggctgcagtgcctcc
aactttgtctttgcgagaaccatgcctgcagaaggagcagatgacattcccgggccggtg
acctgggagccgaagcctgagaactccatctttctaaaatggccagaacctgagaatccc
aacggactgatcctgatgtatgagataaaatatggatcgcaggtcgaggaccagcgggag
tgtgtgcctaggcaggagtataggaagtacggaggggccaagctgaaccggctcaacccg
gggaactacacagcccgcatccaggccacctctctgtctggcaacgggtcgtggacggag
cctgtgttcttctacgtccaggccaaaacgacgtacgaaaacttcatccacctgatcatc
gcgctgccggtcgccgtgctgctcatcgtgggagggctggtaatcatgctgtacgtcttc
cataggaagcggaacaacagcaggctggggaatggcgttctgtacgcttctgtgaaccca
gaatatttcagcgcggcggacgtgtacgtgccggatgagtgggaggtggcccgtgagaag
atcaccatgagccgggagctgggccagggctccttcgggatggtgtacgagggggttgcc
aagggcgtggtcaaagacgagcccgaaacccgggtggcgataaaaactgtcaatgaggct
gcgagcatgcgtgagcgcatcgaatttctcaacgaggcttcagtgatgaaggagttcaac
tgtcaccatgtggtgcgtttgcttggcgtggtgtcgcagggccagccgacgctggtcatc
atggagctcatgacgaggggtgacctcaaaagctatcttaggtctctgaggccggaaata
gagaaagtgccggtccgcggtcgcgctcgttggcgtctctccggagctctgtgtgacgtg
gccggccagcaggtgcccggcgtgagcacgaggcggaggctgcggtctctgcaatctcag
aataacccagcctttgcacctccgagcctgagcaagatgatccagatggccggggagata
gcagacggcatggcgtacctcaacgccaacaagttcgtgcacagagaccttgctgcccgg
aactgcatggtggctgaagacttcacggtcaaaatcggagatttcggcatgacaagagac
atctacgagacagactactaccggaaaggagggaaaggacttctgcccgtgcgctggatg
tcccccgagtccctcaaggacggcgttttcaccactcactctgacgtctggtccttcggg
gttgtcctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaatgag
caagtcctgcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgac
atgctgtttgagctcatgcgtgtgtgctggcagtacaaccccaagatgaggccctccttc
ctggacatcatcggcagcatcaaggacgagatggagcccggcttccaggaggtgtccttc
tactacagtgacgagaacaagccacccgagcccgaggagctggagctggagcccgacaac
atggagagcgtgccgctggacccatcggcgtcctcttactccctgccgctgcctgacaga
tactcgggacacaaggctgagaacggcccgggccctggcgtgctggtcctgcgggccagc
ttcgacgagagacggccttactcgcacatgaatggagggcgcaagaacgagagggccctg
cctctgccccagtcgtccacctgctga
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integrated database retrieval system
