Desmodus rotundus (common vampire bat): 112306266 Help Entry 112306266         CDS       T05907                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism dro  Desmodus rotundus (common vampire bat) Pathway dro04064   NF-kappa B signaling pathway dro04066   HIF-1 signaling pathway dro04145   Phagosome dro04151   PI3K-Akt signaling pathway dro04217   Necroptosis dro04613   Neutrophil extracellular trap formation dro04620   Toll-like receptor signaling pathway dro04621   NOD-like receptor signaling pathway dro04936   Alcoholic liver disease dro05132   Salmonella infection dro05133   Pertussis dro05134   Legionellosis dro05135   Yersinia infection dro05140   Leishmaniasis dro05142   Chagas disease dro05144   Malaria dro05145   Toxoplasmosis dro05146   Amoebiasis dro05152   Tuberculosis dro05161   Hepatitis B dro05162   Measles dro05164   Influenza A dro05170   Human immunodeficiency virus 1 infection dro05171   Coronavirus disease - COVID-19 dro05205   Proteoglycans in cancer dro05235   PD-L1 expression and PD-1 checkpoint pathway in cancer dro05321   Inflammatory bowel disease dro05323   Rheumatoid arthritis dro05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     112306266 (TLR4)    04066 HIF-1 signaling pathway     112306266 (TLR4)    04151 PI3K-Akt signaling pathway     112306266 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     112306266 (TLR4)   09143 Cell growth and death    04217 Necroptosis     112306266 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     112306266 (TLR4)    04620 Toll-like receptor signaling pathway     112306266 (TLR4)    04621 NOD-like receptor signaling pathway     112306266 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     112306266 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     112306266 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     112306266 (TLR4)    05161 Hepatitis B     112306266 (TLR4)    05171 Coronavirus disease - COVID-19     112306266 (TLR4)    05164 Influenza A     112306266 (TLR4)    05162 Measles     112306266 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     112306266 (TLR4)    05135 Yersinia infection     112306266 (TLR4)    05133 Pertussis     112306266 (TLR4)    05134 Legionellosis     112306266 (TLR4)    05152 Tuberculosis     112306266 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     112306266 (TLR4)    05144 Malaria     112306266 (TLR4)    05145 Toxoplasmosis     112306266 (TLR4)    05140 Leishmaniasis     112306266 (TLR4)    05142 Chagas disease     112306266 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     112306266 (TLR4)    05321 Inflammatory bowel disease     112306266 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112306266 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     112306266 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:dro04131]     112306266 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:dro04054]     112306266 (TLR4)    04090 CD molecules [BR:dro04090]     112306266 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:dro00536]     112306266 (TLR4) Membrane trafficking [BR:dro04131]  Endocytosis   Phagocytosis    Toll-like receptors     112306266 (TLR4) Pattern recognition receptors [BR:dro04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    112306266 (TLR4) CD molecules [BR:dro04090]  Proteins   112306266 (TLR4) Glycosaminoglycan binding proteins [BR:dro00536]  Hyaluronan   Cell surface receptors    112306266 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_5 LRR_Zer-1 LRR_EndoS LRR_9 LRR_LRWD1 ThsB_TIR LRR_R13L1-DRL21 Motif Other DBs NCBI-GeneID:  112306266 NCBI-ProteinID:  XP_024417890 LinkDB All DBs Position Unknown AA seq 840 aa AA seqDB search MMSPTRLAGTLIPAMAFLSCLRPESWNPYVQVAPNITYQCVELKFYKILHNISTSAKTLD LSFNPLRCLGNHSFSSFPELQVLDLSRCEIEMIADNAYQGLNHLSTLILTGNPLRSLAMG AFSGLSSLQTLVAVETNLASLEDFPIGHLKTLKELNVAHNLIDSFKLPEYFSNLTNLEHL DLSNNNIQNIYRGDAQVLHQMPPFKLSLDLSLNPLDFIQPGAFEKMELRELTLRSNFNST DIMKTCVQGLAGLKINRLVLGEFKNERIIPEFDKSVLEGLCNLTTEEVRIAFFDNFPEDD LDFLNCLANVSTISLVNLRLHRIGAPPKDFKWQNLKLANCHLKQFPRLELAFLKEFVFTD NKGMSFFTDIRLPILEFLDLSRNGLSFKGCCDHTDFGTTRLKHLDLSFNDVITMGSNFLG LEQLEYLDFQHSNLKQASDFPVFLSLKNLLYLDISYTNMRVIFHGIFDGLVSLQVLKMAG NNFEDDFLPNIFTDLTNLTFLDLSNCQLERVSQEAFGSLPRLRLVNMSHNNLLSLDMRPY KYLPLQILDYSFNHIVAAKSQELQYFPSSLVSLNLTQNEFACVCEHMSFLQWVRDHRHLL VGAEQMLCVKPLEMQGMSVLSFRNATCHMSKTIISVTVLSVLVVSVVAVLIYKFYFHLML LVGCKKYGRGECTYDAFVIYSSHDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSHAGIIFIVLQKLEKSLLR QQVELYRLLSRNTYLEWEDSALGRHIFWRRLRKALLDGKSWSPEGTEDAGRSQHEATTST NT seq 2523 nt NT seq  +upstreamnt  +downstreamnt atgatgtctcccacccgcctggctgggactctgatcccagccatggccttcctctcctgc ctgagacctgagagctggaacccttacgtgcaggtggctcctaacatcacttaccagtgc gtggagctgaagttctacaaaatccttcataacatctctacatcagccaagacactggac ctgagctttaaccccctgaggtgtttaggcaaccatagcttctccagcttcccagaactg caggtgctggatttatccaggtgtgaaattgagatgattgcagataatgcttatcaaggc ctaaaccatctctccaccttgatattgacgggaaaccctctacggagtttagccatggga gccttttctggactatcaagtttacagacactggtggctgtggagacaaacctggcatct ctagaggacttccccattggacacctgaagaccttgaaggagcttaatgtggctcacaat cttatcgattccttcaagttacctgaatacttttctaacctgactaacctggagcacttg gacctttccaataacaacatccaaaatatttatcgtggagatgcgcaggttctccatcaa atgcccccattcaaactctctctagatctgtccctcaaccctttagactttatccaacca ggtgcctttgaaaaaatggagctccgtgaactgactttgagaagtaattttaatagtaca gatataatgaaaacttgtgttcaaggtctggctggtttaaaaatcaatcggttggttctg ggagaatttaaaaatgaaaggatcataccagagtttgacaaatctgtcctggagggactg tgcaatttgactactgaagaagtccgaatagcattcttcgataactttccagaggatgac cttgactttttaaattgtttggcaaatgtttctacaatttctctggtgaatctgcgttta cacaggatcggagctcctcctaaagatttcaaatggcaaaacttaaagttggctaattgt catttgaaacaatttcccagactggagcttgcctttctcaaagagtttgttttcactgac aacaaaggtatgtccttttttactgatattcgtctaccaatccttgagtttctagatctc agtagaaatggcttgagtttcaagggttgctgtgatcacactgattttgggacaaccaga ctgaaacacctggatctgagcttcaacgatgttattaccatgggttcaaacttcttgggc ttagagcaactagaatatctggatttccagcattccaacttgaaacaggccagtgacttt ccagtattcctctctctcaaaaacctcctttaccttgatatttcttatactaacatgcga gttatcttccatggaatctttgatggcttggtcagcctccaagtcttgaaaatggctggc aataattttgaggatgacttccttccaaatatcttcacagacttgacaaacttgaccttc ctggacctctctaattgtcaactagaacgagtgtcccaggaggcatttggctcactccct agacttcggttggtaaatatgagtcacaacaacctcttgtccttggatatgcgtccttat aaatatctccccctccagattctggattacagttttaatcacatagtggctgccaagagt caagaactacagtattttccaagtagcctagtttccttaaatcttactcagaatgagttt gcttgtgtttgtgaacacatgagttttctgcagtgggtccgggaccacaggcacctcttg gtgggagctgagcaaatgttgtgtgtgaaacctttagagatgcagggtatgtctgtgctc agttttagaaatgccacctgtcacatgagcaagactatcattagtgtgacagttctctct gtactggtggtatctgtggtagcagttctgatctataagttctatttccacctgatgctt ctggttggctgcaaaaagtatggccgaggtgagtgcacctatgatgcctttgttatctac tcgagccatgatgaggactgggtgaggaatgagttggtcaagaacttggaggagggggta cccccctttcagctctgccttcactacagagactttattcctggtgtagccatcgccgcc aacatcatccaggaaggtttccacaaaagccggaaggttattgtggtcgtgtcccagcat ttcatccagagccggtggtgcatctttgagtatgagattgcccagacctggcagtttctg agcagtcatgccggcatcatcttcattgtcctgcagaagttggagaagtccttgctccgg cagcaggtggagctgtatcgccttctcagcaggaacacttacctggagtgggaggacagt gccctggggaggcacatcttctggagacgactcagaaaagccttgctggatggtaaatcg tggagcccagaaggaacagaggatgcaggaagaagccagcatgaagcaacaacctccacc tga

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