Desmodus rotundus (common vampire bat): 112306383
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Entry
112306383 CDS
T05907
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro03060
Protein export
dro04141
Protein processing in endoplasmic reticulum
dro04156
Integrated stress response (ISR) signaling pathway
dro04612
Antigen processing and presentation
dro04918
Thyroid hormone synthesis
dro05012
Parkinson disease
dro05014
Amyotrophic lateral sclerosis
dro05020
Prion disease
dro05022
Pathways of neurodegeneration - multiple diseases
dro05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
112306383 (HSPA5)
04141 Protein processing in endoplasmic reticulum
112306383 (HSPA5)
09140 Cellular Processes
09143 Cell growth and death
04156 Integrated stress response (ISR) signaling pathway
112306383 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
112306383 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
112306383 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
112306383 (HSPA5)
05014 Amyotrophic lateral sclerosis
112306383 (HSPA5)
05020 Prion disease
112306383 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
112306383 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112306383 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
dro03110
]
112306383 (HSPA5)
04131 Membrane trafficking [BR:
dro04131
]
112306383 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dro04147
]
112306383 (HSPA5)
Enzymes [BR:
dro01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
112306383 (HSPA5)
Chaperones and folding catalysts [BR:
dro03110
]
Heat shock proteins
HSP70 / DNAK
112306383 (HSPA5)
Membrane trafficking [BR:
dro04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
112306383 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
112306383 (HSPA5)
Exosome [BR:
dro04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
112306383 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
112306383 (HSPA5)
Exosomal proteins of colorectal cancer cells
112306383 (HSPA5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
FtsA
Hydantoinase_A
FGGY_C
DDR
Motif
Other DBs
NCBI-GeneID:
112306383
NCBI-ProteinID:
XP_024418082
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEESADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctagtggctgcggtgctgctgctgctcggcgcggcgcgggccgaggag
gaggataagaaagaggacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgttggggtgtttaagaatggccgcgtggagatcattgccaacgatcagggcaaccgt
atcacgccgtcttatgtggccttcactcccgaaggggagcgtctgatcggcgatgcagcc
aagaaccagctcacctccaaccccgagaacacggtcttcgacgccaagcggctcatcggc
cgcacttggaatgacccgtctgtgcagcaggacatcaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatacattcaagttgacattggaggtggccaaacaaagacattt
gctcctgaagaaatatccgctatggttctcaccaaaatgaaggaaaccgctgaggcttat
ttgggaaagaaggttactcacgcagttgttactgtaccagcctatttcaatgacgcccaa
cgccaggcaactaaagatgctggaactattgctggattgaatgtcatgaggatcatcaat
gagcctacagcagctgctattgcttatggcctggataagagggaaggggagaagaacatc
ctggtgtttgacctgggtggtggaacctttgatgtgtctcttctcaccattgataatggt
gtctttgaagttgtggccactaatggcgatactcatctgggtggagaagactttgaccag
cgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagacgtaaggaaa
gacaacagagctgtgcagaaactccgacgagaggtagagaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagatttctctgag
accctgactcgggccaaatttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaagtgctggaagattctgatttgaagaaatctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacaactggtgaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaagctgtagcgtatggtgctgctgtc
caggccggtgtgctctctggcgatcaagatacaggtgatctggtactgcttgacgtatgt
ccccttacgcttggtattgaaactgtgggaggtgtcatgaccaaactgattcctaggaac
actgtggtgcccaccaagaagtcacagatcttctctacagcctctgataatcagccaact
gttacaatcaaggtttatgaaggtgaacgacccctgacgaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggcaac
aaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgcagagaagtttgctgaagaagacaaaaagctcaaggagcgcattgat
actagaaatgaattggaaagttatgcctattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaatcgtgcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggcgaagaggaatcagcagacaaagatgagttgtag
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