Desmodus rotundus (common vampire bat): 112306435
Help
Entry
112306435 CDS
T05907
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00790
Folate biosynthesis
dro01100
Metabolic pathways
dro01240
Biosynthesis of cofactors
dro01523
Antifolate resistance
dro04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
112306435 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112306435 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112306435 (FPGS)
Enzymes [BR:
dro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
112306435 (FPGS)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
112306435
NCBI-ProteinID:
XP_024418169
LinkDB
All DBs
Position
Unknown
AA seq
588 aa
AA seq
DB search
MPRAHSHLRAALFLAAVSPLGATPRVVGRRAWSARPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQTQMEAMKLYLAQSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDSSSRVSMPSYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIVRKPVVCGVSSLGIDHTSLLGDTMEKI
AWQKGGIFKHGVPAFTVLQPEGPLAVLKERAEQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDHQGIGELKAFRPNPLGQLPLAPVFQPTSHMRLGLQGTE
WLGRTQVLRRGSLTWYLDGAHTCSSVQACVRWFRQALHRLEKPSKGPEVCVLLFNSTGDR
DAAALLKLLQPCRFDYAVFCPNLTEVSPVDNADQQNFTVTLDQVLLRCLEHQQHWSRLHE
EQASPDLWGTPSLEPAGPQSLLLAPRPPHTHSTSSLVFSCISHALQWISQGRDPVFQTPS
PAQGLLAHPVADSGARVLRQAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgccccgggcgcacagccacctgcgcgccgctctcttcctggcagcggtttctccgctt
ggtgcaacgcccagggtcgtgggaaggcgagcgtggagcgcaaggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactcaataccttgcagaccaatgccagc
tacctggagcaggtgaagcgccagcggggcgatccccagacacagatggaagccatgaag
ctgtacttggcacagagcgggcttcaggtggaggacttggaccagctgaacatcatccat
gtcactgggacgaaggggaagggttccacgtgtgccttcactgaacgtatcctccgaaac
tatggcctgaagactggattctttagctctccccacctggtgcaggtacgcgagcggatc
cgaatcaatgggcagcccatcagccctgagctcttcaccaagcacttctggcgcctctat
catcgcctggaggagaccaaggacagcagcagccgtgtctccatgcccagctacttccgt
ttcctaacacttatggctttccatgtcttcctccaagagaaggtggacctggccgtggtg
gaagtgggcattggtggggcttatgactgcactaacattgtcaggaagcctgtggtgtgt
ggggtctcctctcttggcatcgaccacaccagccttctgggggacaccatggagaagatt
gcgtggcagaaggggggcatcttcaagcacggcgtccccgccttcaccgtgctccagccg
gaaggtcccctggcagtgctgaaggagcgcgctgagcagatctcatgtcccctctacctg
tgtccaccgctggaagccctggaggaaggagggccaccgctgaccctgggcctggaggga
gaacaccagcggtccaatgccgccttggccttgcagctggcccgctgctggctgcagcaa
aaggaccaccaaggcatcggggagctgaaagcattcaggccaaaccccctgggtcagctg
cctctggcgcctgtgttccagcccacatcccacatgcggctcgggcttcaaggcacggag
tggctgggccggactcaggtgctacggcgtgggtccctcacctggtacctggatggcgcg
cacacctgcagcagtgtgcaagcctgtgtgcgctggttcagacaggcgctgcaccgcctg
gagaagcccagcaaggggcctgaagtctgtgtcttgctcttcaactccactggggaccgg
gatgccgccgctctgctaaagctgctgcagccctgccggtttgactacgctgttttctgc
cctaacctgacagaggtgtcgcccgtggacaacgcagaccagcagaacttcaccgtgacc
ctggaccaggtgttgctccgctgtttggagcaccagcagcactggagccgcctgcatgag
gagcaggccagccccgacctctggggaacccccagcctggagcctgcagggccccagtcc
ctgctgctggcaccccgcccaccccacacccacagcaccagctccctcgtcttcagctgc
atctcccacgctttgcagtggatcagccagggccgggaccctgtctttcagacacccagt
cctgcacagggccttctcgcacaccctgtggcagacagcggggccagagtactccgccag
gccgctgccatccatgtactggtcacagggagcctgcacctggtgggtggtgtcctgaag
ctgctggagccctccctgtcccagtag
DBGET
integrated database retrieval system
