KEGG   Desmodus rotundus (common vampire bat): 112306733
Entry
112306733         CDS       T05907                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X1
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04010  MAPK signaling pathway
dro04014  Ras signaling pathway
dro04015  Rap1 signaling pathway
dro04020  Calcium signaling pathway
dro04151  PI3K-Akt signaling pathway
dro04520  Adherens junction
dro04550  Signaling pathways regulating pluripotency of stem cells
dro04714  Thermogenesis
dro04810  Regulation of actin cytoskeleton
dro04928  Parathyroid hormone synthesis, secretion and action
dro05200  Pathways in cancer
dro05205  Proteoglycans in cancer
dro05215  Prostate cancer
dro05218  Melanoma
dro05224  Breast cancer
dro05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112306733 (FGFR1)
   04014 Ras signaling pathway
    112306733 (FGFR1)
   04015 Rap1 signaling pathway
    112306733 (FGFR1)
   04020 Calcium signaling pathway
    112306733 (FGFR1)
   04151 PI3K-Akt signaling pathway
    112306733 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    112306733 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    112306733 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112306733 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    112306733 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    112306733 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112306733 (FGFR1)
   05205 Proteoglycans in cancer
    112306733 (FGFR1)
   05230 Central carbon metabolism in cancer
    112306733 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    112306733 (FGFR1)
   05215 Prostate cancer
    112306733 (FGFR1)
   05224 Breast cancer
    112306733 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112306733 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:dro04090]
    112306733 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:dro00536]
    112306733 (FGFR1)
Enzymes [BR:dro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     112306733 (FGFR1)
Protein kinases [BR:dro01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   112306733 (FGFR1)
CD molecules [BR:dro04090]
 Proteins
  112306733 (FGFR1)
Glycosaminoglycan binding proteins [BR:dro00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   112306733 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set C2-set_2 ABC1 Pkinase_fungal V-set_CD47 DUF1615 zf-CCCH_9 RIO1
Other DBs
NCBI-GeneID: 112306733
NCBI-ProteinID: XP_024418478
LinkDB
Position
Unknown
AA seq 733 aa
MWSWKCLLFWAVLVTATLCTARPAPTSPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
MVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
HPAQLANGGLKRR
NT seq 2202 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgcctcctcttctgggctgtgctggtcacagccacactctgcacg
gccaggccggccccgacctcgcctgaacaagatgctctcccctcctcggaggatgacgat
gacgatgatgactcctcttcagaggagaaagagacagataacaccaaaccaaaccgtatg
cccgtggctccatactggacgtccccagaaaagatggagaagaaactgcacgcagtgcct
gctgccaagacagtgaagttcaagtgcccttccagtgggacgcctaaccccacactccgc
tggttgaaaaatggcaaagaattcaaacctgaccacaggattggaggctacaaggtccgt
tatgccacctggagcatcataatggactccgtggtgccttctgataagggcaactacacc
tgcattgtggaaaacgagtacggcagcattaaccacacctaccagctggatgttgtggaa
cggtcccctcaccggcccatcctgcaggcagggttgcctgccaacaagacagtggccctg
ggtagcaatgtggagttcatgtgtaaggtgtacagtgacccacagccccacatccagtgg
ctaaagcacatcgaggtgaatgggagtaagattgggccagacaacctgccttatgtccag
atcctgaagacggccggagttaataccaccgacaaagagatggaagtgcttcacttaagg
aatgtctcctttgaggacgcgggggagtatacgtgcttggcgggtaactctatcggactc
tcccatcactctgcatggttgaccgttctggaagccctggaagagagacctgcagtgatg
acctcccccctgtacctggagatcatcatctactgcacgggggccttcctcatctcctgc
atggtggggtccgtcatcatctacaaaatgaagagtggcaccaagaagagcgacttccac
agccagatggccgtgcacaagctggccaagagcatccctctgcgcagacaggtaacagtg
tcggctgattccagcgcgtccatgaactccggggttctgcttgttcggccctcacgtctc
tcctccagcggaacccccatgctggctggggtctccgaatatgagcttcccgaagaccct
cgctgggagctgccccgagacagactggttttaggcaaacccctgggagagggctgcttt
gggcaggtcgtgctggcggaggccattggcctggacaaggacaaacccaaccgtgtgacc
aaagtggctgtgaagatgttgaagtcggatgcaacagagaaagacctgtcggacctgatc
tcagaaatggagatgatgaagatgatcgggaagcacaagaacatcatcaacctgctgggg
gcctgcacgcaggatggccctttgtacgtcatcgtggagtacgcctccaagggcaaccta
cgggagtacctgcaggcccggaggcctcctgggctggagtactgttacaaccccagccac
aacccagaggagcagctctcctccaaggacctggtgtcttgcgcctatcaggtggcccga
ggcatggagtatctcgcctccaagaagtgcatacaccgagacctagccgccaggaacgtc
ctggtgacggaggacaacgtgatgaagattgcagactttggcctggctcgggacattcac
cacatcgactactataaaaagacgaccaacggccgactgcctgtgaagtggatggcaccc
gaggctctgttcgaccggatctacacccaccagagtgatgtgtggtctttcggggtactc
ctgtgggaaatcttcactctgggaggctccccatatcctggcgtgcctgtggaggagctt
tttaagctgctgaaggagggccatcgcatggacaagcccagtaactgcaccaacgagctg
tacatgatgatgcgggattgttggcacgcggtaccctctcaaagacctaccttcaagcag
ctagtagaagacctggaccgcattgtggccttgacctccaaccaggagtacctggacctg
tcaatgcccctggaccagtactctcccagttttcccgacacccgaagctctacctgctcc
tcaggggaggattctgtcttctctcacgagccgctgcctgaggagccctgtctgccccga
cacccagcccagcttgccaatggcggactcaaacgacgctga

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