Desmodus rotundus (common vampire bat): 112307376
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Entry
112307376 CDS
T05907
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00562
Inositol phosphate metabolism
dro01100
Metabolic pathways
dro04014
Ras signaling pathway
dro04015
Rap1 signaling pathway
dro04020
Calcium signaling pathway
dro04024
cAMP signaling pathway
dro04070
Phosphatidylinositol signaling system
dro04919
Thyroid hormone signaling pathway
dro04933
AGE-RAGE signaling pathway in diabetic complications
dro05205
Proteoglycans in cancer
Module
dro_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112307376 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
112307376 (PLCE1)
04015 Rap1 signaling pathway
112307376 (PLCE1)
04020 Calcium signaling pathway
112307376 (PLCE1)
04070 Phosphatidylinositol signaling system
112307376 (PLCE1)
04024 cAMP signaling pathway
112307376 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
112307376 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
112307376 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112307376 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dro04131
]
112307376 (PLCE1)
Enzymes [BR:
dro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
112307376 (PLCE1)
Membrane trafficking [BR:
dro04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
112307376 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
112307376 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
112307376
NCBI-ProteinID:
XP_024419214
LinkDB
All DBs
Position
Unknown
AA seq
2296 aa
AA seq
DB search
MTSEEMAASVLMPVTQRKEVSSQSAVDEISEKVSDISVPKTHSVRQSGQTSHTISKLKKL
KEESSGSNLPKILSISRENIMSDENCNEKFWEKSMPHSVENLNINCNSILENDLRGRPQS
QFCETCDSVTEETGIPSSLEKKVFPGIQLEIDGPPVASSPLGNQLAITETGEAHPESNME
VFPFQYELDRRMPDTFCTLSDNLILDDCGNCVPLPDVGGEQKKNYMAYTCKLVQLAKSCD
NENGQLQCDHCDTLNDEYLCCEGSCQKANVVRSSDSFCRENFTDGPSAKTFLSHFEDFPD
NCEDVEDLLRSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWSYIDM
KKSGLLLPCGRVTGQLSTVVVTQDGSQSLSEAQWYLIYNAVRRGEETEDTIGSLLHFFTK
LPGSETAHERINVGPYIKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGLLN
TFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQS
IYRRVLPVDYLCFLTQNLGTPECQRSLPCLKASISASILNSQNGEHNALEDLVMRFNEVS
SWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFMDQ
SDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLVK
LCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSRSLETED
EDSASEGNSSRKNSLKDKARCQFIIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHGTEL
IPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPASAK
AKLGVLSNTSEPGKFPLLGNAGLSGLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLSNV
FLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRK
QYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLGISTTK
KKKKILMRGESGEATDDEMAGRKAKMHKECRSWSGSDPQDMNEQEESEANAITSPPNLLP
SRRAHSLTTAGSPSLAAGTPSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMKGFQSF
MVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRLGSESAPLYTNLTIDENTSG
LQPDLDLLTRNVSDLGLFIKNKQQLSDSQRQISDAIAAASIVTNGTGVESTSLGIFGVGI
LQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKNDE
SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG
MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG
EKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQA
YNGGNTNPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKR
IKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNAS
GSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSYEGMRQAWEESSSPLSPTTSLS
AIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTTCQLLRTYPAATRIDSSNPNPLMFWL
HGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNM
EPAVYSLTVVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFFF
RVYFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSR
RMEENSSGSTVPASLMFATEERKCFQTHRVTVHGVPGPEPFTVFSINGGTRAKQLLQQIL
TSEQDTKPTATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILNSWFPEEGYVGR
IVLKTQQENLEEKSIVQDDKEVILTSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQ
QTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANKKSSTPKSSQRVLLDQECVFQAQSKWK
GAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQPRGLTSPAQVLTSESVQNKEE
KPVGSLSSSDVTDYRQ
NT seq
6891 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcatgcctgtgactcagagaaaagaggtg
tcttctcagtcagctgtagatgaaattagtgaaaaggtctcggacatcagtgttccaaaa
acacacagtgtcaggcagagtgggcagacttctcataccatctcaaaactgaaaaaactt
aaagaagaatcttctggaagcaacttgcctaagattctctcaatatcaagagagaacata
atgagtgatgagaactgtaatgaaaagttctgggagaaaagcatgccacattctgtggaa
aaccttaacattaactgcaacagcatattggaaaatgatctgcgtggtcgtcctcagagc
cagttttgtgaaacatgcgattctgtcacagaggaaactggaattccttcttcactggaa
aaaaaagtgttccctggaattcaactggaaattgatggacctcccgtggccagtagtccc
ttaggaaatcaattggccatcacagagactggtgaggcacaccctgagagcaacatggag
gtatttccctttcaatatgaacttgacagaagaatgccagacactttctgtaccctatca
gataacttgattttggatgattgtggaaactgtgttcctctgcccgatgttggtggggag
caaaagaaaaattatatggcatatacttgtaaactagtgcagttggcaaaaagctgtgat
aatgagaacgggcagctacaatgtgatcattgtgataccttgaatgatgaatacttgtgc
tgcgaaggttcctgccaaaaggccaatgtagtacgttccagtgacagcttttgcagggag
aattttactgatggtccatctgccaagacctttctgagccattttgaagacttccctgat
aattgtgaagatgtagaagatttgttgagaagtaaaaaggagcggtccactctgctagtg
agaagattttgtaaaaacgacagggaagttaagaaatctgtgtatactgggacaagggca
attgtgagaactctgccttctggtcacattggactggcagcttggagttacatcgatatg
aagaaaagtggtctcttactgccttgtgggagagtaacgggccagctgtcaacagtggtg
gtcacacaagatggaagccaaagtctgtcagaagcccagtggtatttgatctacaatgca
gtgagaaggggagaagaaacagaagatacaattggatctcttctccatttcttcacaaag
ctcccaggctctgagacagcccatgaaaggattaacgttggtccctacataaagcaatgt
gtccgagacaccgtatgtgagtatcgtgccaccctccaaaggacttccatatctcagtac
atcactggttctctcctagaagcaaccacatctttaggagcaagaagcggccttctcaat
acttttggaggatccactggacgaatgatgctgaaagaacgccaaccaggcacctctatg
gccaattccagtgccctcccttcaagttcagctgggatcagcaaggaactgattgatctg
cagcccctcatccagtttcctgaggaagttgccagcatcctgatggagcaggagcagagt
atttaccgaagggtcttgccggttgactatctttgcttcttgacccagaacttgggcact
ccggaatgtcagaggtccctgccctgcctcaaagcatccatctcagcatccattcttaac
tcacagaatggagagcacaatgcccttgaagatcttgtgatgagatttaatgaggtgagc
tcctgggtgacgtggctgatcctcacagcaggctccatggaggagaagcgggaggtcttc
tcgtatttggtgcatgtggccaaatgctgctggaacatgggcaactataacactgtcatg
gagttcttggccggcctcagatcaagaaaggttttaaagatgtggcagtttatggaccag
tctgacctggagaccatgaggagcctgaaggacgccatggctcagcacgagtcttcctgc
gagtacaggaaggtggtgacgcgggcgctgcacatccctggctgtaaggtggttccgttc
tgcggggtgtttctgaaggagctctgtgaagtactagatggagcctccggcctggtgaag
ctctgcccaagatacaattcccaagaagaaactctagagtttgtagctgactacagtgga
caagataattttttacaacgtgtgggacaaaatggcttaaagaattcagagaaagagtcc
accgtcaacagcatctttcaggtcatcaggagctgcagccggagtctggagacagaggac
gaggacagcgccagtgaagggaacagctctaggaaaaactccttgaaggataaagctcga
tgccagtttataattggagatttactggatacagaaaatgacatctttgagcagcccaaa
gaatgggaccctcatggattagaagagccacagaaggcctttgaccatgggacagagctc
atcccgtggtatgtcctgtccatccgagctgatgtgcaccagttcctgctgcagggggcc
acagttatccactatgaccaggacacacacctctcggcccgctgcttcctccagctccag
cctgacaatagcaccttgacctggataaagcccaccactgcctccccagccagtgctaaa
gcaaaacttggtgtgcttagcaacacatctgaacctggaaaattcccattactgggcaac
gctggattaagtggcttggtggagggggtcttggatctgttttcagcaaaggctgtgtac
atgggacaccctagcattgatatacacactgtgtgtgttcagaacaaactgagtaatgtg
tttctctcagagacgggtgtgacactgctctatgggcttcagaccactgacaataggttg
ttgcactttgtggcaccgaagcacacagctaagatgctcttcagcgggttgttggaactc
actagagctgtgagaaagatgaggaagttccctgaccaaagacagcagtggctgcggaaa
caatacgtcagcctctatcaggaggatggacggtatgaaggcccgactttggctcacgct
gtggagctgtttggtggcagacggtggagcactcgaaaccccagccctgggacatctgca
aagagtgccgagaagcccaacatgcagaggaacaacaccttgggcatcagcactaccaag
aaaaagaagaaaatccttatgaggggggagagcggagaggcgaccgacgatgagatggcc
ggccggaaggccaaaatgcacaaagagtgtcggagctggagtggttctgaccctcaagac
atgaatgaacaagaagaatcagaggcgaatgccatcacaagcccgcctaaccttctccct
tccagaagagcccattctctgaccacggctgggtcccctagcttggctgctgggacacca
tctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaagagcccgtccagtgcg
tggagcagcagcagctggcatgggcgcatcaaaggaggaatgaaaggctttcagagcttc
atggtttctgacagtaacatgagttttgttgaatttgttgagctgttcaaatccttcagt
gtaaggagccgcaaggacctgaaggatctctttgacctctacgccgtgccctgcaaccga
ctgggctctgagtcggccccactctacaccaacctgaccattgacgaaaacaccagcggt
cttcagcctgacctagatttgttgaccagaaatgtctcggatttggggttgttcattaag
aataaacagcagctgtcagacagccagaggcagatctctgacgccattgctgctgcaagc
atcgtgacaaatggcactggggtcgagagcacatccctgggcatatttggggttggcata
cttcagctcaatgacttcctagtgaattgccaaggagaacactgcacttacgatgaaatc
ctcagcatcatccagaagtttgagcctagcattagtatgtgtcaccagggcctaatgtca
tttgaaggatttgcaaggtttctgatggataaagataattttgcatcaaaaaatgatgag
tcacaggagaacattaaagaattacagctgcccctgtcctactattacattgaatcttca
cacaacacctacctcacaggccatcagctcaaaggagaatcctcagtagagctctacagc
caggtcctcctgcaaggctgtaggagtgtagagttggactgctgggatggagatgatggg
atgcccatcatttatcatggacacacactgaccaccaagatccccttcaaggaagtggtt
gaagccattgatcgtagtgccttcatcaactctgacctgccaatcatcatatcgattgag
aaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaagactgtgtttgga
gaaaaactggtagctaaattcttatttgagagtgatttctcagatgatccaatgcttcct
tcacctgaccaacttagaaggaaggtgcttcttaaaaataagaagctaaaagctcatcag
acaccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagctcaggct
tataatggtgggaataccaaccccccacctgctaataacgaggaggaagaagatgaagag
gatgagtatgattatgactatgaatccctctctgatgacaacattctagaagacagacct
gaaaataaatcatgtaacgacaagcttcagtttgagtataatgaagaaatccccaagagg
ataaagaaagcagataactctgcttgcaacaaaggaaaggtatatgatatggaactggga
gaagaattttatcttcctcagaataaaaaggagagcagacagattgcacccgagctttct
gaccttgtcatctattgccaagcagtaaaatttccaggcctgtcaactctaaatgcatct
ggctctaacagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggc
agaatgagccctggggagacagcatcatttaacaaaacatctggaaaaagttcctatgaa
ggaatgcgacaggcctgggaggaatcttcttcccccctcagcccaaccacgtccctcagc
gctatcattagaactcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaa
cgtctgtgtcgcaggtattctcagaaactgatccagcacaccacctgtcagctgctcagg
acctacccagccgccacccgcatcgactcatccaaccccaacccccttatgttctggctg
catgggatacagctcgtggcgctcaactaccagaccgatgatctccctttgcatttaaat
gctgccatgtttgaggccaacggtggctgtggctatgttttgaaacctccagttctgtgg
gacaagaactgtcccatgtaccagaaattttctcccttggaaagagacctggacaacatg
gagcccgccgtctactctttaactgtcgtctctggtcagaatgtgtgcccaagtaacagc
acgggaagcccgtgtatcgaggttgatgtcctgggcatgccgctggacagctgccacttc
cgcacgaagcccatccatcgaaacactctgaaccccatgtggaatgagcagttcttcttc
cgggtttacttcgaagaccttgtgttccttcgttttgcagtcgtggaaaacaacagctca
gcagtcactgctcagagaatcatcccactcaaggctttgaaacgaggatatcgacatctc
cagctgcgaaacctccacaatgaagtcctagaaatctctagtttattcataaacagcaga
aggatggaagaaaattcctctggcagtactgtgccagcctctttgatgtttgctacagaa
gaaagaaaatgttttcagactcacagagtcacggtacatggggtcccaggcccagaaccc
tttactgttttctccataaatggaggcaccagggcaaagcagcttctccagcaaattcta
acctctgaacaagacaccaaacctactgccacagactattttctgatggaagaaaaatat
tttatatctaaagaaaagaatgaatgcagaaaacaaccgttccagagagccattggtcca
gaagaagagatcgtgcagattttaaacagctggtttccagaagagggatacgttggcagg
attgtcttaaaaacccagcaggaaaacctagaagagaaaagcattgttcaggatgacaaa
gaggtgatcttgacctcagaggaggagagtttctttgtccaagtgcacgacgtttcccca
gaacaacctcgaaccgtcatcaaagcaccccgcgtcagcacagcacaggatgttattcag
cagaccttatgcaaagccaagtactcctatagcattctgagcaaccccaacccgagtgac
tacgtgcttttggaagaggtggtgaaagacacagccaacaagaagtcttccacccccaag
tcctcccagcgggtccttttggatcaggagtgtgtgtttcaagcccaaagcaagtggaaa
ggtgcagggaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagacaaa
aggaaaggcatttcttttgcaagtgagctcaagaagctcaccaagtcgaccaaacagccc
cgaggactcacatcacctgctcaggtcttgacctcagaaagtgtccaaaacaaggaggag
aaacctgtgggaagcttgtcctccagtgacgtgacagactatcgacagtga
DBGET
integrated database retrieval system
