KEGG   Desmodus rotundus (common vampire bat): 112307726
Entry
112307726         CDS       T05907                                 
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro00230  Purine metabolism
dro00670  One carbon pool by folate
dro01100  Metabolic pathways
dro01523  Antifolate resistance
Module
dro_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:dro00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    112307726 (ATIC)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    112307726 (ATIC)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    112307726 (ATIC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dro04147]
    112307726 (ATIC)
Enzymes [BR:dro01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     112307726 (ATIC)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     112307726 (ATIC)
Exosome [BR:dro04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   112307726 (ATIC)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS Ribosomal_L12_N
Other DBs
NCBI-GeneID: 112307726
NCBI-ProteinID: XP_024419621
LinkDB
Position
Unknown
AA seq 591 aa
MPSLSALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEML
GGRVKTLHPAVHAGILARNTPEDNTDMARLDFSLIRVVVCNLYPFVKTVASPDVTVEEAV
EQIDIGGVTLLRAAAKNHARVTVVCEPQDYAAVSTEMQSSGSKDTSLETRRQLALKAFTH
TAQYDEAISDYFRKQYGKGISQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLC
DALNAWQLVKELKEAVGIPAAASFKHVSPAGAAVGIPLSEDEARVCMVYDMHETLTPVST
AYARARGADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNGN
YCVLQMDQSYSPDENEVRTLFGLRLSQKRNNGVIGRSLFSNVVTKNKDLPDPALRDLTVA
TIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMRFKAG
VKRAEISNAIDQYVTGTIGEGEDLVKWKALFEQVPELLTEAEKKEWVGKLSEVSLSSDAF
FPFRDNVDRAKRSGVAYIAAPSGSAADRVVIEACEELGIILAHTSLRLFHH
NT seq 1776 nt   +upstreamnt  +downstreamnt
atgccttctctttcagccttgtttagtgtgtctgacaaaaccggccttgtggaatttgcc
agaaacctaacttctgttggtttgaatctgatcgcttctggagggactgcaaaagctctc
agggatgccggcctggcagtcagagatgtctctgagctgacagggtttcctgaaatgtta
ggggggcgtgtgaaaaccttacatcctgcagtgcatgctggaatcttggctcgtaacacc
ccagaagataacactgacatggccagacttgatttcagtcttataagagttgttgtttgt
aacctgtatcccttcgtgaagacagtggcttctccagatgtaactgttgaagaggctgtc
gaacaaatcgatattggcggagtaaccctgctgagagcagcagccaaaaaccacgctcga
gtgaccgtggtgtgtgagccgcaggactacgccgccgtgtccacggagatgcagagctcc
ggcagtaaagacacctccttggagaccaggcgccagctggccttgaaggcttttactcac
acggcacaatacgatgaagccatttcagattacttcaggaagcagtacggtaaaggaata
tctcagatgcccttgaggtacggaatgaaccctcaccaaactccagcccagttatacaca
ctccagcccaagctccccatcacagttctgaatggagcccctggatttattaacttgtgt
gatgctttgaatgcctggcagctggtgaaggaactcaaggaagccgtaggcattccagct
gctgcctctttcaagcacgtcagccccgcaggcgctgctgttggaattccacttagtgaa
gatgaggccagggtctgcatggtctatgacatgcatgagacccttacacccgtatcaact
gcatatgctcgagcaagaggagccgataggatgtcttcatttggtgactttgttgcatta
tctgatatatgtgatgtccctactgccaaaattatctccagagaggtatctgatggaatt
gttgcaccaggatatgaagaagaagctttgaaaatactttctaaaaagaaaaacgggaac
tactgcgttctccagatggaccagtcttacagtccagatgaaaatgaagttcgaactctc
tttggtcttcgtttaagccagaagagaaataatggtgtcatcggcaggtcattatttagc
aatgttgttaccaagaataaagatttgccggaccctgcgctcagagacctcactgtggcc
accatcgctgtgaagtacacgcagtctaactccgtgtgctacgccaagaatggccaggtt
attggcatcggagcaggacagcagtctcggatccactgcacacgcctcgcgggagataag
gcgaactcttggtggcttagacaccatccacgagtactgtcgatgaggttcaaagccgga
gtgaagagagcggaaatctccaatgccatcgatcagtatgttactggaaccatcggcgag
ggtgaagatttagtcaagtggaaggcgctgttcgagcaggtccctgaattactaactgag
gcagagaagaaagaatgggttggcaaacttagcgaagtctctctcagctccgacgccttc
ttccctttcagggataatgtagacagagctaaaaggagtggcgtggcgtatattgctgct
ccgtccggttccgctgctgacagagtcgtgattgaggcctgcgaggaactgggaatcatc
ctcgctcacacgagtcttcgcctctttcatcactga

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