Desmodus rotundus (common vampire bat): 112308288
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Entry
112308288 CDS
T05907
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00220
Arginine biosynthesis
dro00330
Arginine and proline metabolism
dro01100
Metabolic pathways
dro04020
Calcium signaling pathway
dro04022
cGMP-PKG signaling pathway
dro04066
HIF-1 signaling pathway
dro04071
Sphingolipid signaling pathway
dro04151
PI3K-Akt signaling pathway
dro04370
VEGF signaling pathway
dro04371
Apelin signaling pathway
dro04611
Platelet activation
dro04915
Estrogen signaling pathway
dro04921
Oxytocin signaling pathway
dro04926
Relaxin signaling pathway
dro04931
Insulin resistance
dro04933
AGE-RAGE signaling pathway in diabetic complications
dro05415
Diabetic cardiomyopathy
dro05417
Lipid and atherosclerosis
dro05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
112308288 (NOS3)
00330 Arginine and proline metabolism
112308288 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
112308288 (NOS3)
04371 Apelin signaling pathway
112308288 (NOS3)
04066 HIF-1 signaling pathway
112308288 (NOS3)
04020 Calcium signaling pathway
112308288 (NOS3)
04071 Sphingolipid signaling pathway
112308288 (NOS3)
04022 cGMP-PKG signaling pathway
112308288 (NOS3)
04151 PI3K-Akt signaling pathway
112308288 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112308288 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
112308288 (NOS3)
04921 Oxytocin signaling pathway
112308288 (NOS3)
04926 Relaxin signaling pathway
112308288 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112308288 (NOS3)
05418 Fluid shear stress and atherosclerosis
112308288 (NOS3)
05415 Diabetic cardiomyopathy
112308288 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
112308288 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
112308288 (NOS3)
Enzymes [BR:
dro01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
112308288 (NOS3)
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Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
112308288
NCBI-ProteinID:
XP_024420250
LinkDB
All DBs
Position
Unknown
AA seq
1221 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTSEPSWTPAPAPAPAPPPAPDPSGLS
GVHPKENTSPAPNSPPHTRSPEGPKFPRVKNWVVGSITYDTLSAQAQQDGPCTPRRCLGS
LVFPRKLQSRPGQGPPPAEQLLSQARDFINQYYSSIKRGGSQAHEQRLQEVEAEVAATGT
YQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICSHIKYATNRG
NLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPG
NGRFDVLPLLLQAPDEPPELFTVPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLE
IGGLEFPAAPFSGWYMSSEIGMRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEI
NVAVLHSYQLSKVTIVDHHAATSSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQ
EMVNYFLSPAFRYQPDPWKGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATI
LYGSETGRAQGYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPEN
GESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGAL
GTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLPMGQGDELCGQEEAFRGWAKAA
FQASCETFCVGEDAKAATRDIFSPKRSWKRQRYRLSAQAEGLQLLPGLMHVHRRKMFQAT
VLSVENLQSSKSTRATILVRLDTGGQAWLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPP
PGEPVAVEQLEKGSPGGPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAE
EPGEQQELETLSQDPLHYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSV
SSAPSAHLGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLP
PDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQ
DAQQRGVFGRVLTAFSREPDSPKTYVQDILRTELAAEVHRVLCLEGGHMFVCGDVTMATS
VLQTVQRILATEGDMELEEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQE
RHLRGAVPWAFDPPGSDTPAP
NT seq
3666 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagccggggccaccctgcggcctggggctgggg
ctgggcctcggcctgtgtggcaagcagggcccagcctccccgacatctgagcccagctgg
acaccagcacctgcacctgcacccgcacccccgcctgcgccagaccccagtgggctctct
ggggtacatccaaaagaaaacacttcccctgctcccaacagccccccgcacacccggtcc
ccagaggggcccaagttccctcgtgtgaagaactgggtagtggggagcatcacctacgac
accctgagtgcccaggcgcagcaggatgggccatgcacccctcgacgctgcctgggctcc
ctggtatttccacggaaactgcagagccggcccggccagggccccccgcccgccgagcag
ctgctgagccaggccagggacttcatcaaccagtactacagctccatcaagaggggcggc
tctcaggcccacgagcagaggcttcaggaggtggaagctgaggtggcagctacaggcacc
taccagcttcgggagagtgaactggtgttcggggccaagcaggcctggcgcaatgccccc
cgctgtgtgggccggatccagtgggggaagctgcaggtgtttgacgcccgggactgcagc
tctgcacaggagatgttcacctacatctgcagccacatcaagtacgctaccaaccgtggc
aacctccgctcggccatcacagtgttcccccagcgcgccccgggccgcggagacttccgg
atctggaacagccagttggtgcgctacgccggctacaggcagcaggacggctccgtgcgg
ggcgacccggccaacgtggagatcaccgagctctgcatccagcacggctggaccccaggc
aacggccgcttcgacgttctgcccctgctgctccaggccccagatgagcccccagaactc
ttcactgtgccccccgagctagtcctcgaggtgcctctggagcacccgacgctggagtgg
ttcgcagccctgggcctgcgctggtacgccctccccgctgtgtccaacatgctgctggaa
attgggggcctggagttccctgcggcccctttcagcggctggtacatgagctcagagatc
ggcatgcggaacctgtgtgaccctcaccgctacaacatcctggaggacgtggctgtctgc
atggacctggacacccggacaacctcgtccctgtggaaagacaaagcagccgtggaaatc
aacgtggctgtgctgcacagttaccagctgtccaaagtgaccatcgtggaccaccatgct
gccacatcttccttcatgaagcacctggagaatgagcagaaggcgagggggggctgccct
gccgactgggcctggatcgtgccccccatctcaggcagcctcacccctgtcttccatcag
gaaatggtcaactatttcctgtcccctgccttccgttaccagccagacccctggaagggg
agcgcagccaaaggcactggcattaccaggaagaagacctttaaggaagtggccaatgcg
gtgaagatctctgcctcactcatgggcacagtgatggccaagcgcgtgaaggcgaccatc
ctgtacggttctgagactggccgggcccagggctacgcgcagcagctggggaggctcttc
cggaaggcttttgacccccgggtcctgtgcatggatgagtatgacgtggtgtcccttgaa
cacgagacgctggtgttggtggtgaccagcacatttgggaatggggatcccccagagaat
ggagagagcttcgcagcggccctgatggagatgtccggcccctacaacagctccccccgg
cctgagcagcacaagagttacaaaatccgcttcaacagcatttcgtgctcagacccgctg
gtgtcctcctggcggcggaagaggaaggagtccagcaacacggacagcgcgggggccctg
gggaccctcaggttctgtgtgttcgggctgggctcccgggcatacccccacttctgtgcc
tttgcccgtgcggtggacacgcggctggaagagctgggcggggagcggctcctacccatg
ggccagggtgatgagctgtgtggccaggaggaggccttccgcggctgggccaaggccgcc
ttccaggcctcctgtgagaccttctgcgtgggagaggatgccaaggctgccacccgggac
atcttcagccccaaacggagctggaagcgccagaggtaccggctgagtgcgcaggccgag
ggcctccagctgctgccaggcctgatgcacgtgcacaggaggaagatgttccaggccacc
gtcctctcagtggaaaaccttcaaagcagcaagtccacccgggccacgatcctggtgcgc
ctggacactggaggccaggcctggctccagtatcagccaggggaccacataggcgtctgc
ccgcccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccaccacca
cccggcgagccagtggcggtggagcagctggagaagggcagccctggtggccctcccccc
ggctgggtgcgggacccccggctgcccccctgcacgctgcgccaggccctcaccttcttc
ctggacatcacttccccgcccagccctcagctccttcgactgctcagcaccctggctgaa
gagcccggcgaacaacaggagctcgagaccctcagccaggaccccctgcactatgaggag
tggaagtggttccgttgccccacgctactggaggtgctggagcagttcccatcggtggcg
ctgcccgccccgctgcttctcacccagctgcccctgctccagccccggtactactcagtc
agctcagcgcccagcgcccacctgggggagatccacctcacagtggccgtgctggcatac
aggacccaggatgggctgggtcccctgcactacggagtctgctccacgtggctgagccag
ctcaaggccggggaccctgtaccctgcttcatccgaggggctccctccttccggctgcca
cctgaccccagcttgccatgcatcctggtgggcccgggcaccggcatcgcccccttccgg
gggttttggcaagagcggctgcacgacattgagagcaaagggttgcagcccgcccccatg
actttggtgtttggctgccggtgctcccagcttgaccacctctaccgcgacgaggtgcag
gatgcccaacagcgcggggtgtttggccgagtcctcactgccttctcccgggaacccgac
agccctaagacctacgtgcaggacatccttcggacagagctggctgctgaggtgcaccgc
gtgctgtgcctggaaggaggacacatgtttgtctgcggcgatgtcaccatggcaaccagc
gtcctgcagacggtgcagcgcatcctggcgacagagggcgacatggagctggaggaggcc
ggcgacgtcattggcgtgctgcgggatcagcaacgctatcatgaggacattttcgggctc
acgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggag
cggcatctgcggggcgcagtgccctgggctttcgacccgcccggctcagacaccccggct
ccctga
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integrated database retrieval system
