Desmodus rotundus (common vampire bat): 112308507 Help Entry 112308507         CDS       T05907                                  Symbol NF1 Name (RefSeq) neurofibromin isoform X1   KO K08052   neurofibromin 1 Organism dro  Desmodus rotundus (common vampire bat) Pathway dro01521   EGFR tyrosine kinase inhibitor resistance dro04010   MAPK signaling pathway dro04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112308507 (NF1)    04014 Ras signaling pathway     112308507 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     112308507 (NF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  112308507 NCBI-ProteinID:  XP_024420551 LinkDB All DBs Position Unknown AA seq 2774 aa AA seqDB search MRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREG NQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDC AKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAE KLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDAVDENNMNKKLFLDSLRKAL AGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRG SQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWP KIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETR SYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAME ALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICR NKFLLKNKQADRSSCHFLFFYGVGCDIPSSGTTSQLSMDHEELLRTCTPGASLRKGKGNM SMDSAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDE VSVHNFLPNYNTFMEFASVSNMMSTGRTALQKRVMALLRRIEHPTAGNTEAWEDTHAKWE QATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLC ALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLSLMVCN HEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQFVEQTI AIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMAR RDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPL QPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCT VLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRF ERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEV ELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTR LEQSESLEENQRNLLQMTEKFFQAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEK KENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKI LQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVL ALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLT SSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIY HVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSW VREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALR LAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIAN QGTPLTFMHQECDAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSS DPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLE FLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINE KQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKL VSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFH VVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLF GISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKW LDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTY NSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTL DSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAI VARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTD ISMENVPMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAATYPTVGQTSPRARKSMSLD MGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRIS AAQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAE ASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQS FGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTSPYPPA VQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQR STGSFKRNSIKKIV NT seq 8325 nt NT seq  +upstreamnt  +downstreamnt atgagaatatttggagaagctgctgaaaaaaatttgtatctctctcagttgattatattg gatacactggaaaaatgtctcgctgggcaaccaaaggacacaatgagattagatgaaaca atgctcgtgaaacagttgctgccggaaatctgccattttcttcacacctgtcgtgaagga aaccaacatgcagctgaacttcggaattctgcctctggggttttattttccctcagctgc aacaacttcaatgcagtctttagtcgcatttctaccaggttacaggaattgaccgtttgt tcggaagacaatgttgatgttcatgatatagaattgttacaatatatcaatgtggactgt gcaaaattaaaacgactcctgaaggaaacagcatttaaatttaaagccctaaagaaggtt gcacagttagcagttataaatagcctggaaaaggcattttggaactgggtagaaaattat ccagatgaatttacaaagctataccagattccacagactgatatggctgagtgtgcagaa aaactgtttgacttggtggatggtttcgctgaaagcaccaaacgtaaagcagcagtttgg ccactacaaatcattcttcttatcttgtgtccagaaataatccaggatatatccaaggat gcggtcgatgaaaataacatgaacaagaagttgtttctggacagtctacgaaaagcactt gctggccatggaggaagcaggcagctgaccgaaagtgctgcaattgcctgtgtcaaactg tgtaaagcaagtacctacatcaattgggaagataactccgtcattttcctactagttcag tccatggtggttgatcttaagaacctgctttttaatccaagtaaaccattctcgagaggc agtcagcctgcagatgtggatctaatgattgactgcctcgtttcctgctttcgtataagc cctcacaacaaccaacacttcaagatttgcctggctcagaattccccgtctacatttcac tacgtgctggtaaattcactccatcgaatcatcaccaattctgcactggattggtggccc aagattgatgccgtgtattgtcactcagttgaacttcgaaatatgttcggtgaaacactt cataaagcggtgcagggctgcggagcacacccagcgatacgaatggccccgagtcttaca tttaaagaaaaagtaacaagccttaaatttaaagaaaaacctacagacctggagacgaga agctacaagtatcttctcttgtccatggtgaaactaattcatgcagatccaaagctcttg ctttgtaatccaagaaaacaggggcctgaaacccaaggcagtacggcagaattaataaca gggcttgtccaactggtccctcagtcacacatgccggagatcgctcaggaagcaatggag gctctgctggttcttcatcagttagatagcattgacttgtggaaccccgatgctcctgta gaaacgttttgggaaattagctcacaaatgcttttttatatctgcaagaaattaacgagc catcaaatgcttagtagcacagaaattctcaaatggttgcgggaaattctgatctgcagg aataagtttcttcttaaaaataagcaggcagatagaagctcctgtcactttctattcttt tatggggtaggatgtgacattccttcaagtggaactaccagtcagctgtccatggaccat gaagagctactccgtacttgtactcctggcgcctctctccggaaggggaaaggaaacatg tccatggacagtgcagcagggtgcagtggaaccccaccaatatgccgacaggcccagacc aaactggaagtggccctgtacatgtttctgtggagccccgacactgaagctgtcctagtt gccatgtcctgtttccgccacctatgtgaggaagcagatatccggtgtggggtggatgaa gtgtcggtgcacaacttcctgcccaactacaatacattcatggagtttgcctctgtcagc aatatgatgtcgacgggaagaacagcccttcagaagagagtgatggcactactgaggcgc attgagcatcccactgcaggcaacactgaggcttgggaagatacgcatgcaaaatgggaa caagctacaaaactaatcctcaactatccaaaagccaaaatggaagatggccaggctgct gaaagccttcacaagaccattgttaagaggcgaatgtctcatgtgagtggaggaggatcc attgatttgtctgacacggactccctacaggaatggatcaacatgactggcttcctttgt gcccttgggggagtgtgcctgcagcagaggagcagttctggcctggccacctatagccca cccatgggtccagtcagtgaacgcaagggttccatgatttcagtgatgtcctcagaggga aatgcagatacgcctgtcagcaaatttatggaccgactgctgtccttaatggtgtgtaac catgagaaagtgggactgcagatacggaccaatgtgaaggacctggtgggtctagaattg agtcctgctctttatccaatgctatttaacaaattgaagaataccatcagcaaattcttc gactcacaaggacaggttttactgactgacaccaatactcagtttgtagagcaaaccata gctataatgaagaacttactagataaccacactgaaggcagctctgaacacttggggcaa gctagcattgaaacaatgatgttaaatttggtcagatatgttcgtgtgcttgggaatatg gtccatgcaattcagataaaaacgaaactgtgtcagttagtcgaggtgatgatggcaagg agagatgacctctcattttgtcaagagatgaaatttaggaataagatggtagaatacttg acagactgggttatgggaacatcaaaccaagcagcagatgatgatgtcaaatgtcttaca agagatttggaccaggcaagcatggaagcagtagtttcgctcctggctggtcttccactg cagcctgaggaaggagatggcgtggaactaatggaagccaaatcacagttatttcttaag tatttcacattgtttatgaaccttttgaatgactgtagtgaagttgaagatgaaaatgca cagacaggtggcaggaaacgtggcatgtctcggaggctggcctcactgaggcactgtaca gtccttgcgatgtccaacttgctcaatgctaacgtggacagcggcctcatgcactcgata ggtttaggttatcacaaagatctccagacaagagctacgttcatggaagttctgacaaaa atcctccaacaaggcacagaatttgacacccttgcagaaacagtgttggcagatcggttt gagagattggtggagctggtcacgatgatgggtgatcagggggagctccctatagctatg gctctggccaatgtggttccttgttctcagtgggatgaactagctcgagttctggtgact ctctttgattctcggcatttgctctaccaactgctttggaacatgttttctaaggaagta gaattggcagactccatgcagactcttttccgaggcaacagcttagctagtaaaataatg accttctgtttcaaggtatacggtgctacctatcttcagaaacttctggatcctttatta cgaattgtgatcacatcttctgattggcagcacgttagctttgaagtggatcctaccagg ttagaacagtcagagagcctcgaggaaaaccagcggaacctccttcagatgactgagaag ttcttccaggccatcatcagttcctcctcagaatttccccctcagcttcggagtgtgtgc cactgtttataccaggcaacttgccactccctactgaataaagctacagtaaaagaaaaa aaggaaaacaaaaaatcagtggttagccagcgttttcctcagaacagcatcggagcagta ggaagtgccatgttcctcaggttcatcaaccctgccattgtctcaccgtatgaagcaggg attttagataaaaagccaccacctagaattgaaaggggcttgaagttaatgtcaaagata cttcaaagtattgccaatcatgttctcttcacaaaagaagagcatatgcggccttttaat gattttgtaaaaagcaactttgacgccgcgcgaaggtttttccttgatatagcatctgat tgtcctacaagtgatgcagtaaatcatagtctttccttcatcagtgatggcaatgtgctt gctctgcatcgtctgctctggaacaatcaagagaaaattggccagtatctctccagcaac agggatcacaaagctgtggggagacggccttttgataagatggcaacgcttcttgcatac ctgggtcctccagagcacaaacccgtggcggatacgcactggtccagtctcaacctcacc agttcgaagtttgaggaattcatgactaggcatcaagtacatgaaaaagaagagttcaag gctttgaaaacattaagtattttctaccaagctgggacttccaaagctgggaatcctata ttttattatgttgcacggaggttcaaaactggtcaaatcaacggtgacttgctaatatat cacgtcttgctgactttaaagccatattatgcaaagccatatgaaatcgtagtggacctt acccatactgggcctagcaatcgctttaaaacggacttcctctctaagtggtttgttgtt tttcctggctttgcttatgacaatgtctctgcagtttacatctataactgtaactcctgg gtcagggagtataccaagtatcacgagcggctgctgactggcctcaaaggcagcaaaagg ctcattttcatagactgccctggaaaactggccgagcacatagaacacgaacaacagaaa ctccccgctgccaccttggctttagaagaggacctgaaggtgttccacaatgccctcagg ctagctcacaaagacaccaaggtttctattaaagttggttctactgctgtccaagtaacc tcagcagagcgaacgaaagtcctggggcagtcagtctttctaaatgatatctactatgct tcggaaattgaagaaatctgcctggtggatgagaaccagttcaccctaaccatcgccaac cagggcacaccactcaccttcatgcaccaggagtgcgatgccatcgtgcagtccatcatc cacatccggacacgctgggagctgtcgcagcccgactccatcccccagcacaccaagatt cggcccaaagatgtccctgggaccctgctcaatatcgcattactgaacttaggcagttcg gacccgagtttacggtcagctgcctataatcttctgtgtgccttaacttgtacctttaat ttaaaaatcgagggccagttactagagacttcaggtttatgtatccctgccaacaacacc ctctttattgtctccatcagtaagacactggccgccaatgagccacacctcaccttagaa tttttggaagagtgtatttctggatttagcaaatctagtattgagttaaaacacctttgt ttagaatacatgactccatggctgtcaaatctagtccgtttttgtaagcacaacgatgat gccaaacgacaaagagttactgctattctggataagctgataacaatgaccataaatgag aagcagatgtacccatctatccaagcaaaaatatgggggagccttgggcagattacagat ctccttgatgttgtactagacagtttcatcaaaaccagtgcaacgggcggcttgggatcg ataaaagctgaggtgatggcagatactgctgtagctctggcttctggaaacgtgaaattg gtttcaagcaaggttattggaaggatgtgcaaaataattgacaagacatgcttatctcca acccctactttagaacaacatctcatgtgggacgatattgctattctcgcacgctacatg ctgatgctgtctttcaacaactccctggatgtagcagctcatctcccctacctcttccat gtggtcactttcttagtggccacagggccactctcccttagagcttccacacatggattg gtcattaatatcattcactctctgtgtacttgttcacagcttcattttagtgaagagacc aagcaggttttgcgactcagtttgacagagttctcattacccaaattttacttgctgttt ggcatcagcaaagtcaagtcagctgctgtcattgccttccgctccagttaccgggacagg tcattctctcccggctcctatgagagggagactttcgctttgacatccttggaaacagtc acagaggctttgctggagatcatggaggcatgtatgagagatattccgacatgcaagtgg ctggaccagtggacagaactagctcaaaggtttgcgtttcaatataatccatcccttcaa ccaagagctcttgtcgtcttcggctgcattagcaaacgagtgtctcatgggcagataaaa cagattatccgtattctcagcaaggcacttgaaagttgcttaaaaggacctgatacttac aacagtcaagttctgatagaagccacagtaatagcactaaccaaattacagccgctcctt aataaggactcccctttgcacaaagccctcttttgggtagctgtggctgtgctgcagctt gatgaggtcaacttgtattcagcaggcaccgcacttctggaacaaaacctgcacacccta gacagtctccggatattcaatgacaagagcccggaggaagtgtttatggctatccggaat cctctggaatggcactgcaagcagatggatcatttcgttggactcaatttcaactcgaac tttaacttcgcactggttggacacctcttaaaagggtacagacatccgtcacctgccatt gttgcaagaacagtcagaattttgcatacgctactaactctggttaacaaacatagaaat tgtgacaaatttgaggtgaatacacagagcgtggcttatttagcagctttactcacagtg tctgaggaggttcgaagtcgctgtagcctaaaacataggaagtctcttcttcttactgat atttcaatggaaaatgttcctatggatacatatcccattcatcatggcgaccctagctat aggacactgaaggagaatcaaccatggtcctctcccaaaggttctgaggggtaccttgca gccacgtatccaactgtgggccagaccagtccccgagccaggaaatccatgagtttggac atggggcagccttctcaggccaacacgaagaagttgcttggaacaaggaaaagttttgat cacttgatatcagacacaaaggctcctaaaaggcaagaaatggaatcagggatcacaaca ccccccaaaatgaggagagtagcagaaactgattatgaaatggaaactcagaggatttcc gcagcacagcagcacccacatttacggaaagtctcggtgtcagaatcgaatgttctcttg gatgaagaagtacttactgatccaaagatccaagcgcttcttcttactgttctggctaca ctggtaaaatataccacggacgagtttgatcaacgaattctttatgaatatttagcagaa gccagtgttgttttccccaaagtttttcctgttgtgcacaatttgttggactctaagatc aacaccctactgtcgttatgccaagatccaaatttgttaaatccaattcatggaattgtg cagagtgtggtgtaccacgaagaatcccctccacagtaccagacatcttacctgcaaagt tttgggtttaatggcttgtggcggtttgcaggacccttttcaaagcaaacacaaatccca gactatgctgagcttattgttaagtttcttgatgccttgattgacacgtatttgcctgga attgatgaagaaaccagtgaggagtccctcctgacacccacatctccttatcctcctgca gtgcagagccagcttagtatcactgctaaccttaacctttctaattccatgacctcactt gcaacttcccagcattccccaggaatcgacaaggagaacgtggaactctccccgaccacc gggcactgtaacagtggacggactcgccatggatccgcaagccaagtgcagaagcaaaga agcactggcagtttcaaacgtaatagcattaagaagatcgtgtga

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