Desmodus rotundus (common vampire bat): 112308600 Help Entry 112308600         CDS       T05907                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism dro  Desmodus rotundus (common vampire bat) Pathway dro00220   Arginine biosynthesis dro00330   Arginine and proline metabolism dro01100   Metabolic pathways dro04020   Calcium signaling pathway dro04066   HIF-1 signaling pathway dro04146   Peroxisome dro04371   Apelin signaling pathway dro04926   Relaxin signaling pathway dro05010   Alzheimer disease dro05014   Amyotrophic lateral sclerosis dro05022   Pathways of neurodegeneration - multiple diseases dro05133   Pertussis dro05140   Leishmaniasis dro05142   Chagas disease dro05145   Toxoplasmosis dro05146   Amoebiasis dro05152   Tuberculosis dro05200   Pathways in cancer dro05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:dro00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     112308600 (NOS2)    00330 Arginine and proline metabolism     112308600 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     112308600 (NOS2)    04066 HIF-1 signaling pathway     112308600 (NOS2)    04020 Calcium signaling pathway     112308600 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     112308600 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     112308600 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112308600 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     112308600 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     112308600 (NOS2)    05152 Tuberculosis     112308600 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     112308600 (NOS2)    05145 Toxoplasmosis     112308600 (NOS2)    05140 Leishmaniasis     112308600 (NOS2)    05142 Chagas disease     112308600 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     112308600 (NOS2)    05014 Amyotrophic lateral sclerosis     112308600 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     112308600 (NOS2) Enzymes [BR:dro01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      112308600 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  112308600 NCBI-ProteinID:  XP_024420667 LinkDB All DBs Position Unknown AA seq 1153 aa AA seqDB search MAYLWKFLFKAKSHLAKEADINNNVGKTVRAPYSAVTQDDPKGHSLGKPQNESLQPFAGT VKKSPESLVKLNAPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDLACKSKYCLGAIMNSK SLTRGPRDKPTSPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTG DELIYATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHLRYATNNGNIRSA ITVFPQRSDGKHDFRVWNSQLIRYAGYQMPDGTIRGDPACVEFTQLCIDLGWKPKYGRFD VVPLVLQADGCDPELFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVSNMLLEVGGLE FPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVIEINVAVL HSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEMLNY VLSPFYYYQVEAWKTHVWQDEKRRPQRRGIRFQVLVKAVLFASMLMRKTMASRVRATILF ATETGKSETLAQDLGALFSCAFNPKVLCMDEYRLSHLEEEQLLLVVTSTFGNGGAPGNGE KLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDVDQKLSHLGASQLTPTGEGDELS GQEEAFRSWAVQTFKAACETFDVRGKDHIQIPKLYTTSVTWDPRHYRLVPDSQPLDLNKA LSSVHAKDVFTLKLKSRQNLQSPKSSRTTLLVELSCSGSQGLSYLPGEHLGVFPSNQPAL VQGILERVVDGTAPHQPMCLETLSETGSYWVRDKRLPPCSLSQALTYFLDITTPPTQLLL RKLAQLATEEEDRQRLETLCQPSEYNKWKFTNSPTFLEVLGEFPSLRVSASFLLSQLPVL KPRYYSISSSRDRTPMEVHLTVAVLTYRTQDGQGPLHHGVCSTWLSSLKPEDPVPCFIRS ASGFQLPEDPSHPCILIGPGTGIAPFRSFWQQRLYDVEHKGIQGGRMTLVFGCRRPDEDH LYREEMLEMAQKRVLHEVHTAYSRLPGQPKGYVQDILQQQLADQVLHVLHKEQGHLYVCG DVRMARDVTHTLKQLMAAKLSLSEEEVEDYFFQLKDQKRYHEDIFGAVFPYKVKEDGAAG KPNDPRAPTAHGS NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atggcttatctctggaagtttctgttcaaagccaaatcacacttggcgaaggaagcagac atcaacaataatgtggggaaaaccgtccgggctccctacagtgcagtgacccaggatgac cccaagggtcacagccttggcaagccccagaatgagtccctccagcccttcgcggggaca gtgaagaagtctccagagtccctggtcaagctgaatgcgcccccatcggcctgcccaagg cacgtgaggatcaaaaactggggcagtgggatgaccttccaagacacacttcaccacaag gccaaaggggatctcgcttgcaagtccaagtattgcttgggagccatcatgaactccaaa agtttgaccagaggacccagggacaagcctacctccccagacgagcttctacctcaagct atcgaatttgtcaaccagtattacggctccttcaaagaggcaaaaatagaggaacatctg gccagggtggaagccgtaacaaaggagatagaaacaacaggaacctaccagctgacggga gatgagctcatctacgccaccaagcaggcctggcgcaatgccccgcgctgcatcgggagg atccagtggtccaacctacaggtctttgacgcccggagctgctctaccgcccaggaaatg ttcgagcacatctgcagacacctgcgatatgccaccaacaatggcaacatcaggtcggcc atcactgtgttcccccaacggagcgatgggaagcatgacttccgcgtctggaactctcag ctcatccggtatgccggctaccagatgcccgatggcaccatcagaggggaccctgcctgc gtggagttcacccagctgtgcattgacctgggctggaaacccaagtacggccgcttcgac gtggtgcctctggtcctgcaggccgatggctgcgaccctgagctcttcgaaatcccgcct gaccttgtgcttgaggtgcctatggaacatcccaagtacgagtggttccgggagctggag ctgaagtggtacgccctgcctgcggtgtccaacatgctgctcgaggtgggcggcctcgag ttcccggggtgccccttcaatggctggtacatgggcacagagatcggggtccgggacttc tgtgatgtccagcgctacaacatcctggaggaagtgggcagaaggatgggcctggaaacg cacaagttggcctcactctggaaagaccaggctgtcattgagatcaatgtcgccgtgctc cacagtttccagaagcagaacgtgaccatcatggaccaccactcggccgctgagtccttc atgaagtacatgcagaatgagtaccggtcccgagggggctgccctgccgactggatttgg ctggtccccccgatttctggaagcatcacccccgtgttccaccaggagatgttaaactac gttctgtcccctttctactactaccaggtggaggcctggaaaacccatgtctggcaggac gagaagcggagaccccagagaagagggattcggttccaagtcttggttaaagccgtgctc ttcgcctctatgctgatgcgcaagaccatggcatcccgagtcagagccacaatcctcttt gcgacagagacgggaaagtcagaaacgctcgcccaggacctgggcgccttgttcagctgc gccttcaaccccaaggttctctgcatggacgagtacaggctgagccacctggaggaggag cagctgctgctggtggtgaccagcacgtttgggaacggaggcgccccaggcaacggagag aaactgaagaaatccctcttcatgctgaaagagctcaccaacaagttcaggtatgccgtg ttcggccttggttccagcatgtaccctcagttctgcgcctttgctcatgatgtcgaccag aagttgtcccacctgggagcgtctcagctcaccccgacaggggaaggggacgagctcagt gggcaggaagaggccttccgcagctgggccgtgcagacattcaaggcagcctgtgagacc ttcgacgtccgaggcaaggaccacattcagatccccaagctctacaccaccagtgtgacc tgggacccgcgccactaccggctcgtgcccgactcacagcctttggacctcaacaaagcc ctcagcagtgtgcacgccaaggatgtgttcaccctgaagctcaagtcacggcagaacctg cagagtccgaaatccagccgcaccaccctcctggtggaactctcctgttcgggcagccaa ggtctcagctacctgccaggggagcacctgggcgttttcccaagcaaccagccggccctg gtccaaggcattttggagcgagtggtggatggcactgcaccccaccaacccatgtgcttg gagaccctcagcgagaccggcagctactgggtcagggacaagcggctgcccccctgctcc ctcagccaggccctcacctacttcctggacatcaccacccccccaacacagctgctgctc cgaaagctggcccagctggccactgaagaggaggacaggcagaggctggagactctgtgc cagccctcggagtacaacaagtggaagttcaccaacagtcccacgttcctggaggtgctg ggggagttcccatccctgcgggtgtctgccagcttcctgctctcacagctccctgttctg aaaccccggtactactccatcagctcatccagggaccgcacacccatggaggtccacctc accgtggctgtgctcacctaccgcacccaagatggccagggtcccctgcaccacggtgtc tgcagcacatggcttagcagcctgaagcccgaagacccagtgccctgtttcatacgaagt gccagcggcttccagctccccgaggacccctcccacccttgcatcctcattgggcctggc acaggcattgcccccttccgcagtttctggcagcagcggctttatgacgttgaacataaa gggatccagggtggccgcatgaccctggtgtttgggtgccggcgcccagatgaggaccac ctctatcgggaggagatgttggagatggcccagaagagggtgctgcatgaggtgcacaca gcctactctcgcctgcctggccaacccaagggctacgttcaagacatcctgcagcagcag ctggctgatcaggtgctccacgtgcttcacaaggagcagggccacctctatgtctgtggg gacgtgcgcatggcccgggatgtgacccacacacttaagcagctgatggcagccaagcta agcctgagtgaggaagaagtggaggactatttcttccagcttaaggaccagaagcgctat catgaagatatctttggtgctgtatttccctacaaggtgaaagaggatggggcagcaggg aagcctaacgatcccagagctccaacagcccacggaagttaa

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