Desmodus rotundus (common vampire bat): 112311145 Help Entry 112311145         CDS       T05907                                  Symbol HIF1A Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism dro  Desmodus rotundus (common vampire bat) Pathway dro04066   HIF-1 signaling pathway dro04137   Mitophagy - animal dro04140   Autophagy - animal dro04148   Efferocytosis dro04659   Th17 cell differentiation dro04919   Thyroid hormone signaling pathway dro05167   Kaposi sarcoma-associated herpesvirus infection dro05200   Pathways in cancer dro05205   Proteoglycans in cancer dro05208   Chemical carcinogenesis - reactive oxygen species dro05211   Renal cell carcinoma dro05230   Central carbon metabolism in cancer dro05231   Choline metabolism in cancer dro05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     112311145 (HIF1A)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     112311145 (HIF1A)    04137 Mitophagy - animal     112311145 (HIF1A)    04148 Efferocytosis     112311145 (HIF1A)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     112311145 (HIF1A)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     112311145 (HIF1A)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112311145 (HIF1A)    05205 Proteoglycans in cancer     112311145 (HIF1A)    05208 Chemical carcinogenesis - reactive oxygen species     112311145 (HIF1A)    05230 Central carbon metabolism in cancer     112311145 (HIF1A)    05231 Choline metabolism in cancer     112311145 (HIF1A)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     112311145 (HIF1A)   09162 Cancer: specific types    05211 Renal cell carcinoma     112311145 (HIF1A)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     112311145 (HIF1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:dro03000]     112311145 (HIF1A) Transcription factors [BR:dro03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     112311145 (HIF1A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  112311145 NCBI-ProteinID:  XP_024423159 UniProt:  K9IN14 LinkDB All DBs Position Unknown AA seq 823 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNGNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNERLQNINLAMSPLPASETPEPLRSSADPALNQEVALKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPTSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSTSTISAFQ PTQMQEPTLTATTTAATTDELKTLTKDGMEDIKILIASPSPTHIPKETTSTTTSPYSDTR SRTASPNRAGKGVIEQTEKSHPRSPNVLSITLSQRTTVPEEELNPKILALQNAQRKRKIE HDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCRSSEQNGMEQKTIILIPSDLACRLL GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN NT seq 2472 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggaggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa aagtctagagatgcagccagatctcggcgaagtaaagagtctgaagttttttatgagctt gctcatcagttgccacttccccataatgtgagttcgcatcttgataaggcttctgttatg aggcttaccatcagctatttgcgtgtgaggaaacttctcgatgctggtgatttggatatt gaagatgaaatgaaagcacaaatgaattgcttttatttgaaagccctggatggttttgtt atggttctcacagatgatggtgatatgatttacatttctgataatgtgaataaatacatg gggttaacgcagtttgaactaactggacacagtgtgtttgattttactcatccgtgtgac catgaggaaatgagagaaatgcttacacacagaaatggccttgtaaaaaaaggtaaagag caaaatacacagcgaagcttttttctcagaatgaagtgtaccctgactagccgggggaga actatgaacatcaagtctgcaacatggaaggtacttcattgcacaggacatattcatgtg tacgataccaatggtaaccagtctcaatgtgggtataagaaaccacctatgacgtgcttg gtgctcatttgtgaacccattcctcatccgtcaaatattgaaattccattagatagcaag actttcctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact gaattgatggggtatgagccagaagaacttttgggccgctcaatttatgaatattatcat gctttggactctgatcatctgaccaaaactcatcatgacatgtttactaaaggacaagtc accacaggacagtaccggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa gccactgtcatatataacactaagaactctcaaccacaatgcattgtatgtgtaaattat gttgtgagtggtattattcaacacgacttgatcttctcccttcaacaaacagaatgtgtc ctgaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca gaagatacaagtagcctctttgataaacttaagaaggaacctgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagattttggcagcaatgacacagaaact gatgaccaacaacttgaggaagttccattatataatgatgtaatgctcccctcatctaat gaaagattacagaatataaatttggcaatgtctccattacctgcctctgaaactccagag ccacttcgaagtagtgctgaccctgcactcaatcaggaagttgcgttaaaattagaacca aatccagagtcactggaactgtcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacaaagttcacctgagcctaccagtccgagtgaatattgt tttgatgtggatagtgatatggtcaatgaattcaagttggaattggtagagaaacttttt gctgaagacacggaagcaaagaatccattttctactcaggacactgacttagacttggag atgttagctccttatatcccaatggatgatgacttccagttacgttcctttgatcagttg tcaccattggaaagcagttctacaagcccccaaagtacaagcacaatctcagcattccag ccaactcaaatgcaagaaccaactcttaccgccaccactaccgctgccaccactgatgaa ttaaaaacactgacaaaagatggtatggaagacattaaaatattgattgcatctccatct cctacccacatacctaaagaaactactagtaccacaacatcaccatatagtgatactcga agtcggacagcctcaccaaacagagcaggaaaaggagtgatagaacaaacagaaaaatct catccaagaagccctaacgtgttatctatcactttgagtcaaagaactactgttcctgag gaagaactaaatccaaagatactagctttgcagaatgctcaaagaaaacgaaaaatagaa catgatggttcactttttcaagcagtaggaattggaacattattacagcagccagatgat cgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcagatctagtgaacag aatggaatggagcaaaagactattattttaataccctctgatttagcatgtagactgctg gggcaatcaatggatgagagtggattaccacagctgaccagctatgattgtgaagtcaac gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagcattggat caagttaactga

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