Desmodus rotundus (common vampire bat): 112312198
Help
Entry
112312198 CDS
T05907
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00310
Lysine degradation
dro01100
Metabolic pathways
dro05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
112312198 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
112312198 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dro03036
]
112312198 (DOT1L)
Enzymes [BR:
dro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
112312198 (DOT1L)
Chromosome and associated proteins [BR:
dro03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
112312198 (DOT1L)
HMT complexes
Dot1-containing complex
112312198 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
112312198
NCBI-ProteinID:
XP_024424348
LinkDB
All DBs
Position
Unknown
AA seq
1545 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTAAPSPQDAYKSPQSPFYQLPPSVQRQPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELMQLK
SCVPPDDSVSLHLRGKGSLGRELEAEPGRLHLELDCSKFSLPHFSSMSPELSMNGHVAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASVKASAGELHPRAEHTKENGLPYQSPGLTNGIKLSPQDPQPSPPMALQM
TGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGANGHGAGSNAAGSKGLALAPTGFSYTGSVAISGALAGSPAP
LAAGAEPPAFDESSSSGSLFTTMSSRSSTPQHHQLLVQPRNSGSASPTHQLCVSPRLSAA
QGPLPDSSKGDLPPETGFSDPESEAKRRIIFTISAGASSAKQSPSNKHSPLPGGARGDSS
QSHGQDSRKRGRRKRTSAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQ
PLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEQG
STRIERKIATISLESKSPPKTLENGGSLIGRKPMPSSEPINSSKWKSTFSPIADLSLAKA
ADSPLQASSALSQNSLFAFRPALEELGSVDAKLAAHPRKSFPGALSGTGGLSPVSNPPNG
FAFSGGLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKEGSAEPGPFVNKRQLD
VLGGPKGEGVKGREAEVGLPMCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAVPTG
GLLSGPGLTTAVSSAGGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSS
VPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGRQKCDSPV
NT seq
4638 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaggaaatcccagacctcaagcttgctatggagaattatgtccta
attgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagttgtggaagggaaccacacagcctatgaagctgaacacg
cggccatccaacgggctcctgcggcacatcctgcagcaggtttacaaccactcggtgacg
gaccctgagaagctcaacaactacgagcccttctccccggaggtgtatggggagacctcc
ttcgacctggtcgcgcagatgattgacgaaatcaagatgacagaggatgacctgtttgtg
gacctgggaagtggagtgggccaggttgtgcttcaggtcgcagcagccaccaactgcaaa
catcactacggagtcgagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcagaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaatatg
aaggaaggtggcagaattgtgtcctcgaagccctttgctcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactacttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcaacagcgagaaaacaagagtaatacgaccacccccacgaaggtgcct
gagagcaaggcggctgtgcctgcagacacctctgtggattctggtgctgaggaagagaag
gcagcaacaaccgctatcaagaagccgtccccctctaaagcgcggaagaagaaactgaac
aagaaggggcggaagctggcaggccggaagcgtggacgtccgaagaagatgagcactgcg
aaccccgagcgtaagcccaagaagaaccctactgcactggacctgctgcacgcccagact
gtgtcccagacggccgcaccctcaccgcaggatgcgtacaagtcacctcaaagcccgttt
tatcagctacctcccagcgtgcagcggcagccccctgaccaactgctgctggcacccacc
ccacccgcactgcagaagctgctagagtccttcaagatccagtacctgcagttcctagca
tacacaaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctgggggccgcacagcagctatttggccactgccaggcccagaaa
gaagaaataaagagactcttccagcagaaactggatgagttgggagtgaaggctctgaca
tacagcgacctaatccaagcgcagaaggagatctcagctcacaaccagcagctccgagag
cagacagagcagctggagaaggacaacagggagctaaggagccagagcctgcagctgctg
aaggctcggtgtgaggagctaaagctggactggtccacactgtccctggagaacctgcta
aaggagaagcaggccctgaagagccagatctctgagaaacagaggcactgtctggagctg
cagatcagcatcgtggagctggaaaagagccagcggcagcaggaacttatgcagctcaag
tcctgcgtgccaccagatgactcggtgtccctgcacctgcgagggaaaggcagcctgggc
cgggaactggaggcggagcctggccggctgcacctcgagctagactgctccaagttctca
ctgccccacttcagtagcatgagcccggagctctccatgaatggccacgtggccggctat
gaactctgcaacacactgagccggccctcatccaaacagaacacccctcagtacttggcc
tccccattggaccaggaagttgtgccctgtacccccagccatagcagccggccccggctt
gagaagctgtctgggttggccttgccagactacaccaggctctctccagccaagctggtg
ctgagacgccacctgagtcaggaccacacagccagtgtcaaggcatctgctggcgagctg
catccacgagctgagcacaccaaggagaatggccttccataccagagcccaggcctcacc
aacggcatcaagctgagccctcaggacccacagccttcaccccccatggccttacagatg
acaggggaaaagggcagtgagaagggtctgaaggagcgcacctatgccagcagtggtgag
gccatcaccagcctacctgtcagcatcccgctcagcaccgtgcagcccagcaagctgcct
gtcagcatccccctggccagcgtggtgttgcccagccgcgccgagaaggtgagaagcacc
cccagccctgtgcctcagacccgagagtcctcatccacacttgaaaagcagatgggtgct
aatggccatggtgctgggagcaacgctgctgggagcaaaggcctcgccctggcccccaca
ggtttctcctacactggctcagtggccatcagtggggccctggcaggcagcccagccccg
ctcgctgctggagctgagcccccggcctttgatgagtcctccagttcagggagcctcttc
accaccatgagctcccgcagctccaccccacagcaccatcaactgctggtgcagccccgg
aactctggttcggcctcaccgactcatcagctctgtgttagtccccggctcagcgctgcc
cagggtccactccctgattccagcaaaggagaccttccccctgagactggcttctcggat
ccagagagcgaggccaagaggaggatcatcttcaccatctcagctggtgccagcagcgcc
aagcagtcgccttccaacaaacacagccctctgccggggggcgcccgcggagacagcagc
cagagccatggacaggatagccgaaagcggggccggaggaagcgaacgtcagcggggact
cccagcctgagctcgggtgtgtcccccaagcgccgggctttgccatccgtcgctggtctc
ttcacgcagtcttcagggtccccactcaacctgaactccatggtcaacaacattaaccag
cctttggaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtccct
taccaggacaatgaccagccgcccgtgctcaagaaggagaagcccctgagccaaaccaat
ggggcccactactccccgctgacctccgatgaggagccgggctctgaggacgagcaaggc
agcaccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccgaaa
accttagaaaatggtggcagtctgataggaaggaagccgatgccctccagcgagcccatc
aacagcagcaagtggaagtccaccttctcgcccatcgccgacctcagcctggccaaggct
gccgacagcccactacaggccagctccgctctgagccagaactccctgtttgctttccgg
cccgccctagaggagcttggctcggttgatgccaagctggccgcccaccccaggaagagc
ttcccgggtgcactgtcagggactggcgggctgagtcccgtcagcaaccctcccaacggc
tttgccttcagtgggggcctggctgccgacctcagtttacacagcttcagcgatggtgct
tctctctcccacaaggcccctgaggtggccagcctgggtgctcccctgagcttttccgcc
cctaggggcaaggagggcagcgcagagcctggcccctttgtgaacaagaggcagctggat
gtattgggtggcccaaagggcgagggggtcaagggcagggaggcagaggtgggcctgccc
atgtgcacaccctcagacaaggcctcgtcgcatggcaaggtgggcaagggccgggaccgt
gagcctgacttcaagaatggccacaatctcttcatttccgctgctgccgtgcctactggg
ggcctcctcagcggtccaggcctcaccacggcagtgtcctcagcaggtggcacagccccc
tcctcccagacacaccggcccttcctgggcactttcgcacctggcccgcagtttgccttg
ggccctatgtccctgcaggccaacctaggctcgtctgtgctgcagtccttgttcagctct
gtgccggctgccgctggcctagtgcacgtctcatcagctgcaacaagactgaccaactcg
catgccatgggcagcttttcctctggtgtggcaggcggtgcagttggaggtaggcagaag
tgcgactctcctgtctga
DBGET
integrated database retrieval system
