Desmodus rotundus (common vampire bat): 112314176
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Entry
112314176 CDS
T05907
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112314176 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
dro01002
]
112314176 (BACE1)
Enzymes [BR:
dro01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
112314176 (BACE1)
Peptidases and inhibitors [BR:
dro01002
]
Aspartic peptidases
Family A1: pepsin family
112314176 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
112314176
NCBI-ProteinID:
XP_024426481
LinkDB
All DBs
Position
Unknown
AA seq
500 aa
AA seq
DB search
MAQALPWLLLWMGSALLPAHCTQPGIRLPLRSGLGGNPLGLRLPRDTEEPEEPCRRGSFV
EMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTY
RDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILG
LAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPFNQSEVLASVGGSMIIGGID
HSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKV
FEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMSEVTNQSFRITI
LPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACH
VHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWR
CLRCLRHQHDDFADDISLLK
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcactgccctggctcctgctgtggatgggctcagcactgctgcctgcccac
tgcacccagcctggcatccggctgcctctgcggagcgggctgggggggaaccccctgggg
ctgcgactgcctcgggacacggaggagccagaggagccttgccggaggggcagctttgtg
gagatggtggacaacctgaggggcaagtctggtcaggggtactatgtggagatgactgtg
ggcagcccccctcagacgctcaacatcctggtggacacaggcagcagtaattttgcagtg
ggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtcaagcacatac
cgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggagctg
ggtaccgacctggtgagcattccccatggccccaatgtcactgtacgtgccaacattgct
gccatcactgagtcggacaagttcttcatcaatggctccaactgggaaggcatcctgggg
ctggcctatgctgagatcgccaggcctgacgattccctggagcctttctttgactccctg
gtaaagcagacccacgttcccaacctcttctccctgcagctatgtggtgctggcttcccc
ttcaaccagtcagaagtgctggcctcagttggagggagcatgatcattgggggtatcgac
cactcgctgtacacaggcagcctctggtacacacccatccggcgagagtggtattatgag
gtgatcattgtgcgggtggaaatcaatggacaggatctgaaaatggactgcaaggagtac
aactatgataagagcatcgtggacagtggcaccaccaatcttcgtttgcccaagaaagtg
tttgaagccgcagtcaaatccatcaaggcagcctcctcgacggagaagttcccagacggc
ttttggctaggggagcagctagtgtgctggcaagcaggcactaccccttggaacatcttc
ccagtcatctcactctacctaatgagtgaggtcaccaatcagtccttccgcatcaccatt
cttccacagcaatacctgcggccagtggaagatgtggccacatcccaagatgactgctac
aagttcgccatctcacagtcatccacgggcactgttatgggagcagttatcatggagggc
ttctatgttgtctttgatcgggcaagaaaacgaattggctttgctgtcagtgcttgccac
gtgcacgatgagttcaggacagcagcggtggaaggcccgtttgtcaccctggacatggaa
gactgtggctacaacattccacagacagatgaatcaaccctcatgaccatagcctatgtc
atggctgccatctgtgccctcttcatgctgccactctgcctcatggtgtgtcagtggcgt
tgcctccgctgtctacgccatcagcacgatgactttgctgatgacatctccctgctgaag
tga
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