Desmodus rotundus (common vampire bat): 112316215
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Entry
112316215 CDS
T05907
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro01521
EGFR tyrosine kinase inhibitor resistance
dro01522
Endocrine resistance
dro01524
Platinum drug resistance
dro04010
MAPK signaling pathway
dro04012
ErbB signaling pathway
dro04020
Calcium signaling pathway
dro04066
HIF-1 signaling pathway
dro04151
PI3K-Akt signaling pathway
dro04510
Focal adhesion
dro04520
Adherens junction
dro04530
Tight junction
dro05200
Pathways in cancer
dro05205
Proteoglycans in cancer
dro05206
MicroRNAs in cancer
dro05212
Pancreatic cancer
dro05213
Endometrial cancer
dro05215
Prostate cancer
dro05219
Bladder cancer
dro05223
Non-small cell lung cancer
dro05224
Breast cancer
dro05226
Gastric cancer
dro05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112316215 (ERBB2)
04012 ErbB signaling pathway
112316215 (ERBB2)
04066 HIF-1 signaling pathway
112316215 (ERBB2)
04020 Calcium signaling pathway
112316215 (ERBB2)
04151 PI3K-Akt signaling pathway
112316215 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
112316215 (ERBB2)
04520 Adherens junction
112316215 (ERBB2)
04530 Tight junction
112316215 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112316215 (ERBB2)
05206 MicroRNAs in cancer
112316215 (ERBB2)
05205 Proteoglycans in cancer
112316215 (ERBB2)
05230 Central carbon metabolism in cancer
112316215 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
112316215 (ERBB2)
05226 Gastric cancer
112316215 (ERBB2)
05219 Bladder cancer
112316215 (ERBB2)
05215 Prostate cancer
112316215 (ERBB2)
05213 Endometrial cancer
112316215 (ERBB2)
05224 Breast cancer
112316215 (ERBB2)
05223 Non-small cell lung cancer
112316215 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112316215 (ERBB2)
01524 Platinum drug resistance
112316215 (ERBB2)
01522 Endocrine resistance
112316215 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dro01001
]
112316215 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dro04147
]
112316215 (ERBB2)
04090 CD molecules [BR:
dro04090
]
112316215 (ERBB2)
Enzymes [BR:
dro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112316215 (ERBB2)
Protein kinases [BR:
dro01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
112316215 (ERBB2)
Exosome [BR:
dro04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
112316215 (ERBB2)
CD molecules [BR:
dro04090
]
Proteins
112316215 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
112316215
NCBI-ProteinID:
XP_024428737
LinkDB
All DBs
Position
Unknown
AA seq
1223 aa
AA seq
DB search
MKLRLPASPETHLDMLRYLYQGCQVVQGNLELTYLPANASLLFLQDIQEVQGYVLIAHNQ
VRQVPLQRLRIIRGTQLFEDNYALAVLDNRGLPDSASPAAGAAPGGLRELQLRSLTEILK
GGVTIQRNPQLCHQDTILWVDIFHKNNQLALTVIDTNRSRACPPCSPDCKYCWGESSRDC
QSLTRTVCASGCARCKGRRATDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALV
TYNTDTFESMPNPEGRYTFGASCVTTCPYNYLSTDVGSCTLVCPVNNQEVTAEDGTQRCE
KCSKPCARVCYGLGVEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFEGDPASNTAPL
QPEQLRVFETLEEITGYLYISAWPDTLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGIQW
LGLRSLRELGSGLALVHHNAHLCFVHTVPWDQLFRNPHQALLHSANRPEDECVGDGLACY
HLCAHGRCWGPGPEQCVNCSQFLRGQECVEECRVLQGLPREYVKDRYCLPCHPECQPQNG
SVTCSGSEADQCVTCAHYKDPPFCVARCPSGVKPDLSFMPIWKFPDEEGTCQPCPINCTH
SCVDLDDKGCPAEQRASPVTSIIAAVVGILLFMVMGTVTGILIRRRRQKIRKYTMRRLLQ
ETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAI
KVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRE
HRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDI
DETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIP
DLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNE
DLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGSTAHRRHRSSST
RSGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGMQSLPVLDPSPLQRY
SEDPTVPLPPETDGYVAPLTCSPQPEYVNQTEVRPKPPSPLEGPLPPPRPAGATLERPKT
LSPGKNGIVKDIFTFGGAVENPEYLAPRSRAAPQPHPPPAFSPAFDNLYYWDQDPSERGS
PPSTFEGTPTAENPEYLGLNVPV
NT seq
3672 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgcgcctcccagccagtcccgagacccacctggacatgctccgctacctctac
cagggctgtcaggtggtgcagggtaacctggagctcacctacctgcctgccaatgccagc
ctcctcttcctccaggatatccaggaggtgcagggctacgtgctcatcgctcacaaccag
gtgagacaggtcccgctgcagaggctgcggatcatacgcggcacccagctctttgaggac
aactacgccctggccgtgctggacaacagaggcctgccggacagcgccagccctgctgca
ggggcggccccaggagggctgcgggagctgcagctgcgaagcctcacagagatcctgaaa
ggaggggtcacgatccagcggaacccccagctctgccaccaggacacgattttgtgggtg
gacatcttccacaagaacaaccagctggccctcacggtgatagacaccaaccgctcccgg
gcctgtccaccctgctctccagactgtaaatactgctggggagaaagctccagggactgt
cagagcttgacccggactgtgtgcgccagcggctgcgcccgctgcaagggccggcgggcc
accgactgctgccacgagcagtgtgctgccggctgcacgggccccaaacactctgactgc
ctggcctgcctccacttcaaccatagtggcatctgtgagctgcactgcccagccctggtc
acctacaacacggacacctttgagtccatgcccaaccctgagggccgttacaccttcggt
gccagctgtgtgaccacctgtccctacaactatctgtcgacggacgtgggatcctgcacc
ctggtctgtcccgtgaacaaccaagaggtgacggctgaggacgggacgcagcggtgtgag
aagtgcagcaagccctgcgctcgagtgtgctatggtctgggcgtggaacacctgcgagag
gtgcgggcggtcaccagtgccaacatccaggagttcgccggctgcaagaagatctttggg
agcctggcgtttctgccagagagctttgagggggaccccgcctccaacactgcccctctc
cagccggagcagctcagagtgtttgagaccctggaggagatcacaggttacctgtacatc
tcagcgtggccagacactctgcctaacctcagtgtcttccagaaccttcgagtcatccgg
ggacgagttctgcatgatggtgcctactcgctgaccctgcaagggctgggcatccaatgg
ctggggctgcgctcgctgcgggagctgggcagtgggctggccctcgtccatcacaacgcc
cacctctgctttgtgcacacggtgccctgggaccagctctttcggaaccctcaccaggcc
ctgctccacagtgctaaccggccagaggacgagtgtgtgggtgatggtctggcctgctac
cacctctgcgcccatgggcgctgctgggggccggggcccgagcagtgtgtcaactgcagc
cagttcctgcggggccaggagtgcgtggaggagtgccgagtcctgcaagggctcccccgc
gagtacgtgaaggacaggtactgtctgccctgccaccccgagtgtcagccccagaatggc
tcggtgacctgttcaggatcggaggctgatcagtgtgtgacttgcgcccactacaaagac
cctcccttctgtgtggcccgatgccccagtggtgtgaaacctgacctctccttcatgccc
atctggaagttcccagatgaggagggcacgtgccagccatgccccatcaactgcacccac
tcctgtgtggatctggatgacaagggctgccctgccgagcagagagccagccctgtgaca
tccatcattgccgctgtggtgggcattctgctgttcatggtcatggggacagtcaccggc
atcctgatcaggaggaggcggcagaagatccgcaagtacacgatgcggaggctgctgcag
gaaacggagctggtggagccgctgacacctagcggagcgatgcccaaccaggctcagatg
cggatcctcaaagagacagagctgaggaaggtgaaggtgcttggatctggagcttttggc
accgtctacaagggcatctggattcccgatggggagaatgtgaaaatcccagtggccatc
aaagtgttgagggaaaacacatctcccaaagccaacaaagaaatcttggatgaagcatat
gtgatggctggtgtgggctccccgtatgtgtcacgcctcctgggcatctgcttgacctcc
acggtgcagttggtgacacagcttatgccctacggctgcctcttagaccacgtccgagaa
caccgcgggcgtctgggctcccaggacctgctgaactggtgtgtgcagattgccaaggga
atgagctatttggaggaggtacggctcgtgcacagggacctggctgcccggaatgttctg
gtcaagagtcctaaccacgtcaagatcacagactttgggttggctcggctgctggacatt
gacgagacggagtaccacgcagatgggggcaaggtgcccatcaagtggatggcattggag
tccattctccgccgacggttcacccaccagagtgatgtgtggagctatggtgtgactgta
tgggagctgatgacttttggggccaaaccttacgatgggatcccggcccgggagatccct
gacctgctggagaagggggaacggctgccccagccccccatctgcaccatcgacgtctac
atgatcatggtcaaatgttggatgattgattctgaatgtcggcctcggttccgggagctg
gtggctgaattctcccgcatggccagggacccccagcgctttgtggtcatccagaacgag
gacttgggccctgccagccccttggacagcaccttctaccggtcgctgctggaggacgac
gacatgggggacctggtggacgctgaggagtacctggtaccgcagcaaggcttcttctgc
ccagaccctgccccgggtgctgggagcacggcccaccgcaggcatcgcagctcctccacc
aggagtggcggtggtgagctgacactggggcttgagccctccgaggaagaaccccccaag
tctccgctggcaccctcagaaggggcgggctctgatgtgtttgacggcgacttgggaatg
ggagcagccaaagggatgcagagcctccccgtgcttgaccccagccctctacagcggtac
agtgaggaccccacagtacccctgccccccgagactgatggctacgttgcccccctgacc
tgcagcccccagccagagtacgtgaaccagacggaggttcgcccgaagcccccctcaccc
ctagaaggccctctgcctcctccgagacctgcaggtgccactctggaaaggcccaagact
ctctccccggggaagaatgggatcgtcaaagacattttcacctttgggggtgctgtagag
aaccccgagtacttggcgccacgcagcagagctgccccgcagccccaccctcctccagcc
ttcagcccagcctttgacaacctctattactgggaccaggacccatcagagcggggctct
ccacccagcacctttgaagggacccctacggcagagaaccctgagtacctgggcctgaac
gtgcccgtgtga
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integrated database retrieval system