Desmodus rotundus (common vampire bat): 112316277
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Entry
112316277 CDS
T05907
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
112316277 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dro03032
]
112316277 (TOP2A)
03036 Chromosome and associated proteins [BR:
dro03036
]
112316277 (TOP2A)
Enzymes [BR:
dro01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
112316277 (TOP2A)
DNA replication proteins [BR:
dro03032
]
Eukaryotic type
DNA Topoisomerases
112316277 (TOP2A)
Chromosome and associated proteins [BR:
dro03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
112316277 (TOP2A)
Centrosome formation proteins
Centriole proteins
112316277 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
112316277
NCBI-ProteinID:
XP_024428852
LinkDB
All DBs
Position
Unknown
AA seq
1529 aa
AA seq
DB search
MEVSPLQPVNENMQISKPKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWRDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFDEWKN
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQTDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTGPTFNYLLDMPLWYLTKEKKD
ELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKAKG
KKAQMAEVLPSPSGKRVIPRVTIEMKAEAEKKNKRKIKNENTEGSPQEDSVEPEGLKQRL
EKKQKREAGTRAKKQNTLPFKPVKKGKKRNPWSDSESDMSGNESDFDVPPREIEPRRAAA
KTKFTVDLDSDEDFSDFDKKSEDEDFVPSDASPIKTKTSPKRMNKEVKPQESTMSVPDLD
DAKDNAPPPPSSSAADFPAETKITNPVSKKRVTVKKITTKSQSSTSTTGAPKRAAPKGTK
KDPSLTSDVPQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKAVTSKKYKAEGDDFHVDL
DSAVAPRVKSGRAKKPIKYLEESDEDDLF
NT seq
4590 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcccgtaaatgaaaatatgcaaatcagcaaacccaagaaa
aatgaagatgctaagaaaagactgtccattgagagaatctatcaaaagaaaacacagttg
gaacatattttgctccgtccggacacctacatcggctcggtggagttagtgacccagcaa
atgtgggtttacgatgaagatgttggcatgaactacagggaagtaacgtttgttcccggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaacgggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaatcagtatatggaat
aatggaaaaggtattcctgttgttgagcacaaagttgagaagatgtatgtcccagctctc
atctttggtcagctcctaacttctagtaactatgatgatgatgaaaaaaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttacagtggaa
acagccagtagagaatataagaaaatgttcaaacagacatggagggataacatggggaga
gctggtgagatggaactcaagccctttaatggagaagattatacatgtattaccttccag
cctgatttgtctaaatttaaaatgcaaagcctagacaaagatattgttgcactaatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat
aagctgccagtgaaaggattccgtagctatgtagacatgtatttgaaggataaggtagat
gaaactggcaatccgctgaaaattatccatgaacaagtaaaccacagatgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcatcgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtggctaaacttgtggatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagaccaaagaaaac
atgactttacaagtcaagagctttggatcaacatgccaactaagtgaaaaattcatcaaa
gctgcaattggttgtggtattgtagaaagcatactaaactgggtgaagtttaaggctcaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactctactgactgtacacttatcctgact
gaaggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tacggagttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
atcatggagaatgccgaaattaacaatatcataaagatcgtgggtcttcagtacaagaaa
aactatgaagatgaagattcactgaagactcttcgttatgggaagatcatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaatttcatccatcacaac
tggccctctcttctgcgacatcgttttctagaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagtcttcctgaatttgacgagtggaagaat
tctacaccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatactttgcagacatgaaaagacatcgtatccagttcaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaagcagacagatgat
cgaaaggagtggctaactcattttatggaggatagaagacaacggaagttacttggcctt
cctgaggactacctgtatgggcaaaccactacatatctgacgtacaatgacttcataaac
aaagaacttatcctgttctcaaattctgataacgagagatctatcccatctatggtcgat
ggtttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggg
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctagatacatcttcacaatgctcagtcctttggctcggttgttatttccacca
aaagatgatcacacattaaagttcttatatgatgacaaccaacgtgtggagcctgaatgg
tacatccctattatacccatggtgctgataaatggcgctgaaggaattggtactggttgg
tcctgcaaaatacccaactttgatattcgtgaggttgtgaataacataaggagattgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggcactattgaa
gagctggcttcaaatcagtatgtcattagtggtgaagtggctatccttaattccaccacc
attgaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaggttcta
gaacccatgttgaatggcactgagaagacgcctcctcttataacagattacagggaatac
catacagacaccacggtgaagtttgtggtgaagatgactgaagagaaactggctgaggcc
gagagagctggactccacaaagtcttcaaactccaaaccagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatatgacacggtgctggatattctaaga
gacttctttgaactcagactgaaatattatggattaaggaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaacaatcaggcacgctttatcttggagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttttgattcagaga
ggatatgattcggatcctgtgaaggcttggaaggaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagcgactctgtaactgga
ccaactttcaactaccttcttgatatgcctctttggtacctaaccaaagaaaagaaagat
gaactgtgcaaactaagaaatgaaaaagaacaagagctagaaacattaaaaagaaagagt
ccatcagatttgtggaaagaagacttggctgctttcattgaagagctagaggctgttgaa
gccaaggaaaaacaagatgaacaagtaggactccctgggaaaggggggaaagcaaagggg
aaaaaagcacaaatggctgaagttttgccttctcccagtggaaaaagagtcatcccccga
gtgaccatagagatgaaagcagaggcagaaaagaaaaataaaaggaaaattaagaatgaa
aatactgaaggaagccctcaagaggatagtgtggaaccagaaggcctaaaacaaagacta
gagaagaaacagaaaagagaagcaggtaccagagcaaagaaacaaaatacattgccattt
aaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagatatgagt
ggtaacgaaagtgactttgatgtccctccacgagaaatagagccacgaagagcagcggca
aaaaccaaattcacagtggatttggattcagatgaagatttctcagattttgataaaaaa
agcgaagatgaagattttgtcccatcagatgctagtccaattaagaccaaaacttcccca
aaacgtatgaacaaagaagtgaagccacaggagagcaccatgtcagtcccagatcttgat
gatgccaaggacaatgcaccacctcctccaagctcatctgcagctgacttcccagccgaa
accaaaatcacaaaccctgtttctaaaaagagagtaacagtaaagaagattacaacaaaa
agtcagtcttccacctccactacaggtgccccaaaaagggctgcaccaaaaggaaccaag
aaggatcccagcttgacttctgatgtccctcaaaagcctgatccccctaaaaccaagaat
cgccgcaaaaggaagccatctacttctgatgattccgactctaattttgagaaaatgatt
tctaaagcagtcacaagcaagaaatacaaggcggagggtgatgatttccatgtggactta
gactccgctgtggcccctcgggtaaaatctggacgggcaaagaaacctataaagtacctc
gaagaatcagatgaggatgatctgttttaa
DBGET
integrated database retrieval system
