Desmodus rotundus (common vampire bat): 112316515 Help Entry 112316515         CDS       T05907                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism dro  Desmodus rotundus (common vampire bat) Pathway dro01521   EGFR tyrosine kinase inhibitor resistance dro04010   MAPK signaling pathway dro04012   ErbB signaling pathway dro04014   Ras signaling pathway dro04015   Rap1 signaling pathway dro04020   Calcium signaling pathway dro04066   HIF-1 signaling pathway dro04070   Phosphatidylinositol signaling system dro04071   Sphingolipid signaling pathway dro04072   Phospholipase D signaling pathway dro04082   Neuroactive ligand signaling dro04150   mTOR signaling pathway dro04151   PI3K-Akt signaling pathway dro04261   Adrenergic signaling in cardiomyocytes dro04270   Vascular smooth muscle contraction dro04310   Wnt signaling pathway dro04360   Axon guidance dro04370   VEGF signaling pathway dro04510   Focal adhesion dro04540   Gap junction dro04613   Neutrophil extracellular trap formation dro04650   Natural killer cell mediated cytotoxicity dro04664   Fc epsilon RI signaling pathway dro04666   Fc gamma R-mediated phagocytosis dro04670   Leukocyte transendothelial migration dro04713   Circadian entrainment dro04720   Long-term potentiation dro04723   Retrograde endocannabinoid signaling dro04724   Glutamatergic synapse dro04725   Cholinergic synapse dro04726   Serotonergic synapse dro04727   GABAergic synapse dro04728   Dopaminergic synapse dro04730   Long-term depression dro04750   Inflammatory mediator regulation of TRP channels dro04911   Insulin secretion dro04912   GnRH signaling pathway dro04916   Melanogenesis dro04918   Thyroid hormone synthesis dro04919   Thyroid hormone signaling pathway dro04921   Oxytocin signaling pathway dro04925   Aldosterone synthesis and secretion dro04926   Relaxin signaling pathway dro04928   Parathyroid hormone synthesis, secretion and action dro04929   GnRH secretion dro04933   AGE-RAGE signaling pathway in diabetic complications dro04935   Growth hormone synthesis, secretion and action dro04960   Aldosterone-regulated sodium reabsorption dro04961   Endocrine and other factor-regulated calcium reabsorption dro04970   Salivary secretion dro04971   Gastric acid secretion dro04972   Pancreatic secretion dro05017   Spinocerebellar ataxia dro05022   Pathways of neurodegeneration - multiple diseases dro05031   Amphetamine addiction dro05032   Morphine addiction dro05143   African trypanosomiasis dro05146   Amoebiasis dro05161   Hepatitis B dro05163   Human cytomegalovirus infection dro05164   Influenza A dro05170   Human immunodeficiency virus 1 infection dro05171   Coronavirus disease - COVID-19 dro05200   Pathways in cancer dro05205   Proteoglycans in cancer dro05206   MicroRNAs in cancer dro05207   Chemical carcinogenesis - receptor activation dro05214   Glioma dro05223   Non-small cell lung cancer dro05225   Hepatocellular carcinoma dro05231   Choline metabolism in cancer dro05415   Diabetic cardiomyopathy dro05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112316515 (PRKCA)    04012 ErbB signaling pathway     112316515 (PRKCA)    04014 Ras signaling pathway     112316515 (PRKCA)    04015 Rap1 signaling pathway     112316515 (PRKCA)    04310 Wnt signaling pathway     112316515 (PRKCA)    04370 VEGF signaling pathway     112316515 (PRKCA)    04066 HIF-1 signaling pathway     112316515 (PRKCA)    04020 Calcium signaling pathway     112316515 (PRKCA)    04070 Phosphatidylinositol signaling system     112316515 (PRKCA)    04072 Phospholipase D signaling pathway     112316515 (PRKCA)    04071 Sphingolipid signaling pathway     112316515 (PRKCA)    04151 PI3K-Akt signaling pathway     112316515 (PRKCA)    04150 mTOR signaling pathway     112316515 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112316515 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     112316515 (PRKCA)    04540 Gap junction     112316515 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     112316515 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     112316515 (PRKCA)    04664 Fc epsilon RI signaling pathway     112316515 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     112316515 (PRKCA)    04670 Leukocyte transendothelial migration     112316515 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     112316515 (PRKCA)    04929 GnRH secretion     112316515 (PRKCA)    04912 GnRH signaling pathway     112316515 (PRKCA)    04921 Oxytocin signaling pathway     112316515 (PRKCA)    04926 Relaxin signaling pathway     112316515 (PRKCA)    04935 Growth hormone synthesis, secretion and action     112316515 (PRKCA)    04918 Thyroid hormone synthesis     112316515 (PRKCA)    04919 Thyroid hormone signaling pathway     112316515 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     112316515 (PRKCA)    04916 Melanogenesis     112316515 (PRKCA)    04925 Aldosterone synthesis and secretion     112316515 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112316515 (PRKCA)    04270 Vascular smooth muscle contraction     112316515 (PRKCA)   09154 Digestive system    04970 Salivary secretion     112316515 (PRKCA)    04971 Gastric acid secretion     112316515 (PRKCA)    04972 Pancreatic secretion     112316515 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     112316515 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     112316515 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     112316515 (PRKCA)    04727 GABAergic synapse     112316515 (PRKCA)    04725 Cholinergic synapse     112316515 (PRKCA)    04728 Dopaminergic synapse     112316515 (PRKCA)    04726 Serotonergic synapse     112316515 (PRKCA)    04720 Long-term potentiation     112316515 (PRKCA)    04730 Long-term depression     112316515 (PRKCA)    04723 Retrograde endocannabinoid signaling     112316515 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112316515 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     112316515 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     112316515 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112316515 (PRKCA)    05206 MicroRNAs in cancer     112316515 (PRKCA)    05205 Proteoglycans in cancer     112316515 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     112316515 (PRKCA)    05231 Choline metabolism in cancer     112316515 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     112316515 (PRKCA)    05214 Glioma     112316515 (PRKCA)    05223 Non-small cell lung cancer     112316515 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     112316515 (PRKCA)    05161 Hepatitis B     112316515 (PRKCA)    05171 Coronavirus disease - COVID-19     112316515 (PRKCA)    05164 Influenza A     112316515 (PRKCA)    05163 Human cytomegalovirus infection     112316515 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     112316515 (PRKCA)    05143 African trypanosomiasis     112316515 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     112316515 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     112316515 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     112316515 (PRKCA)    05032 Morphine addiction     112316515 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112316515 (PRKCA)    05415 Diabetic cardiomyopathy     112316515 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     112316515 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     112316515 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dro01001]     112316515 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:dro04131]     112316515 (PRKCA) Enzymes [BR:dro01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      112316515 (PRKCA) Protein kinases [BR:dro01001]  Serine/threonine kinases: AGC group   PKC family [OT]    112316515 (PRKCA) Membrane trafficking [BR:dro04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     112316515 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  112316515 NCBI-ProteinID:  XP_024429154 LinkDB All DBs Position Unknown AA seq 610 aa AA seqDB search MARRQKQEVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVQDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SIEIWDWDRTTRNDFMGSLSFGVSELMKMPACGWYKLLNQEEGEYYNVPIPEGDDEGNME LRQKFEKAKLGPAKKVISPSEDRRFSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE ELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNG GDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKKGIIYRDLKLDNVMLDSEGHIKIADF GMCKEHMMEGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED EDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDW EKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQ FVHPILQSAV NT seq 1833 nt NT seq  +upstreamnt  +downstreamnt atggcaaggaggcagaaacaagaagtttgctgttttgtggttcacaagaggtgccatgaa tttgtcacattttcttgtccgggtgcggacaaaggacctgacactgacgaccccaggagc aagcacaagtttaagatccacacctatgggagccccaccttctgtgaccactgcgggtcg ctgctgtacgggctcatccaccaggggatgaagtgcgacacctgcgacatgaatgtgcac aagcagtgtgtcataaacgtccccagcctctgtgggatggaccacaccgagaagaggggc cggatctacctgaaggctgaggtcactgatgaaaagctccatgtcacagtgcaagatgca aaaaatctcatccccatggatccaaatggactttcagacccttacgtgaagctgaaactt attcctgaccccaagaatgagagcaaacaaaaaaccaaaactatccgctccacactaaac ccccagtggaatgagtccttcacgttcaaattaaaaccttcagataaagaccgacgactg tccatagaaatctgggactgggatcggacaacaaggaacgacttcatgggatccctttcc tttggcgtttcagagctgatgaagatgccggcctgtgggtggtacaagctgctcaaccaa gaagaaggtgagtactacaacgtgcccattccagaaggggacgatgaaggaaacatggag ctcaggcagaagttcgagaaagccaagcttggccccgccaagaaagtgatcagcccttca gaagacaggcgattttccaacaaccttgacagagtgaaactcactgacttcaatttcctc atggtgctggggaaggggagtttcggaaaggtgatgctggctgacaggaagggaacagaa gaactctacgccatcaaaatcctgaagaaggacgtggtgattcaagacgacgacgtggag tgcaccatggtggaaaaacgggtcctggccctgctcgacaagcccccgttcctgacgcag ctgcactcctgcttccagacagtggaccggctgtacttcgtcatggaatacgtcaacggt ggggacctcatgtaccacattcagcaagtgggaaaattcaaggagccacaggcagtattc tatgcagcagagatttccattggattgttctttcttcataaaaaaggaatcatttatagg gacctgaagttagacaacgtcatgctggactccgaagggcacatcaagatcgctgacttc gggatgtgcaaggagcacatgatggagggggtcacgaccagaaccttctgtgggaccccg gattatatcgccccagagatcatcgcctaccagccgtatgggaaatccgtggactggtgg gcctatggcgtcctgctgtatgaaatgctggccgggcagcctccgtttgacggtgaagat gaagacgagctgttccagtccatcatggagcacaacgtctcgtacccgaaatccctgtcc aaggaggctgtttccatctgcaaaggactgatgaccaagcatccaggcaagcggctgggc tgcgggcccgagggagagcgggacgtgcgcgaacatgccttcttccggaggatcgactgg gagaaactggagaacagggagatccagccgcccttcaagcccaaagtgtgcggcaaaggc gcggaaaactttgacaagttcttcacacgagggcaaccggtcttaacgcctccggatcag ctggtcatcgctaacatagaccagtctgattttgaggggttctcgtacgtcaaccctcag tttgtgcaccccatcttacagagcgcagtatga

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