Desmodus rotundus (common vampire bat): 112318756
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Entry
112318756 CDS
T05907
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro04010
MAPK signaling pathway
dro04020
Calcium signaling pathway
dro04022
cGMP-PKG signaling pathway
dro04024
cAMP signaling pathway
dro04260
Cardiac muscle contraction
dro04261
Adrenergic signaling in cardiomyocytes
dro04270
Vascular smooth muscle contraction
dro04723
Retrograde endocannabinoid signaling
dro04725
Cholinergic synapse
dro04726
Serotonergic synapse
dro04727
GABAergic synapse
dro04911
Insulin secretion
dro04912
GnRH signaling pathway
dro04921
Oxytocin signaling pathway
dro04924
Renin secretion
dro04925
Aldosterone synthesis and secretion
dro04927
Cortisol synthesis and secretion
dro04929
GnRH secretion
dro04934
Cushing syndrome
dro04935
Growth hormone synthesis, secretion and action
dro05010
Alzheimer disease
dro05020
Prion disease
dro05022
Pathways of neurodegeneration - multiple diseases
dro05207
Chemical carcinogenesis - receptor activation
dro05410
Hypertrophic cardiomyopathy
dro05412
Arrhythmogenic right ventricular cardiomyopathy
dro05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112318756 (CACNA1S)
04020 Calcium signaling pathway
112318756 (CACNA1S)
04024 cAMP signaling pathway
112318756 (CACNA1S)
04022 cGMP-PKG signaling pathway
112318756 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
112318756 (CACNA1S)
04929 GnRH secretion
112318756 (CACNA1S)
04912 GnRH signaling pathway
112318756 (CACNA1S)
04921 Oxytocin signaling pathway
112318756 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
112318756 (CACNA1S)
04924 Renin secretion
112318756 (CACNA1S)
04925 Aldosterone synthesis and secretion
112318756 (CACNA1S)
04927 Cortisol synthesis and secretion
112318756 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
112318756 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
112318756 (CACNA1S)
04270 Vascular smooth muscle contraction
112318756 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
112318756 (CACNA1S)
04725 Cholinergic synapse
112318756 (CACNA1S)
04726 Serotonergic synapse
112318756 (CACNA1S)
04723 Retrograde endocannabinoid signaling
112318756 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
112318756 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
112318756 (CACNA1S)
05020 Prion disease
112318756 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
112318756 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
112318756 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
112318756 (CACNA1S)
05414 Dilated cardiomyopathy
112318756 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
112318756 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
dro04040
]
112318756 (CACNA1S)
Ion channels [BR:
dro04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
112318756 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
Motif
Other DBs
NCBI-GeneID:
112318756
NCBI-ProteinID:
XP_024431727
LinkDB
All DBs
Position
Unknown
AA seq
1876 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPAPEILPRPPRALLCLTLENPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNVGLEKLEYFFLVVFSVEAAMKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVDVIQSNTAPLSSKGAGLDAKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFTGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTEVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSPDEGGSDTESLYEIEGLNKLIQFVRHWRQWNRV
FRWKCHDVIKSRAFYWLVILVVALNTLSIASEHHHQPAWLTHLQDVANRVLLSLFTVEML
IKMYGLGLRQYFMSVFNRFDCFVVCSGVLEILLVESGAMSPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDSF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPYYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKPEEEKSVVAKKLDQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSSTNKIRVLCHRIVNATWFTNFILLFIMLSSAALAAEDPIRAESMRNQILGYFDIAFT
SVFTVEIILKMTTYGAFLHKGSFCRNYFNLLDLLVVAVSLVSMRLESSSISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFIFACIGVQLFKGKFFRCTDL
SKMTEEECRGHYYVYKDGDPMQIELRPREWVHNDFHFDNVLSAMMSLFTVSTFEGWPHLL
YRAIDSYEEDKGPVYNNRVEMAIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLKCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHVSDILNVAFTLIFTLEMLLKLVAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTPINRNNNFQTFPQAVLLLFRCA
TGEAWQEVLLASSYGKLCDPESEYAPGEEHSCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLDRPNSLAP
VMANQRPLQFSEIEMEELESPVFLEDFPPGPSTHPLARANTNNANANANAAPGNSHRSSS
PVLASVHYDRESPGEAEPPTAATCAAPGQPCSTLSPHSKSCEGKWRGQLTWGAAPGVQAP
PAPCQRPRAESPVPEVRRSPMPGSLPEEAPHSSRAPESPSRCQAPATAQLIQEALLRGGL
DSWAADAGFIKATSQALAEACRMEPEEVEVAAAELLRRRESSEGSASTLGSRSLQSSLGS
LDQPQGSRETLIPPRP
NT seq
5631 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctccccccaggacgagggcctcaggaagaagcagcccaagaagcctgcc
cctgagatcctgccgaggcccccccgggccctgctctgcctgaccctcgagaacccactg
aggaaggcctgcatcagcatcgtggagtggaaacccttcgagacgatcatcctcctcacc
atcttcgccaactgcgtggcgctggccgtgtacctgccgatgccggaggacgacaacaac
actctgaacgtgggcctggagaagctggagtacttcttcctcgtcgtcttctccgtcgaa
gctgccatgaagattatcgcctacggcttcctcttccaccaggacgcctacctgcgcagc
ggctggaacgtgctcgatttcaccatcgtcttcctgggggtcttcacggtgattctggag
caggtggacgtcatccagagcaacacggccccgctgagcagcaaaggcgccggcctggac
gccaaggccctgagagccttccgcgtgctcaggcccctgcggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgctgccgctgttccacatcgcc
ctgctggtcctcttcatggtcatcatctacgccatcatcggcctggagctcttcaagggc
aagatgcacaagacctgctacttcaccgggaccgacatcgtggccaccgtggagaacgag
aagccatccccctgtgccaggacaggctcaggccgcccgtgcaccatcaacggcagcgag
tgccgaggcggctggccggggcccaaccatggcatcacgcacttcgacaacttcggcttc
tccatgcttacggtgtaccagtgcatcaccatggagggctggaccgaggtcctgtactgg
gtcaacgatgccatcgggaacgagtggccctggatctactttgtcaccctcattctgctg
gggtccttcttcatcctcaacctggtgctgggtgtcctgagcggggagttcaccaaagag
cgggagaaggccaagtccagggggaccttccagaagctccgggagaagcagcagctggag
gaggacctgcggggctacatgagctggataacgcagggcgaggtcatggacgtggaggac
ttgagagaagggaagctgtcgccggatgaaggtggctcggacactgagagcctgtacgag
atcgagggcctgaacaagctcatccagtttgtgagacactggaggcagtggaatcgtgtc
ttccgctggaaatgccacgacgtgatcaagtccagagccttctactggctggtgatcctg
gttgtggccctcaacacgctgtccatcgcttccgagcaccaccaccagccggcgtggctg
acccacctgcaagacgtggccaaccgggtgctgctgtccctcttcaccgtggagatgctg
atcaagatgtacgggctggggctgcgccagtacttcatgtccgtcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcgtcctggagatcctgctggtggagtcgggcgccatgagc
cccctgggcatctccgtgctgcgctgcatccgcctcctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcgtccctgctcaactccatccgctccatcgcc
tcgctgctgctcctgctcttcctcttcatcgtcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtatgacttcgaggacaccgaggtgcgccgcagcaacttcgacagcttc
ccgcaggccctcatcagcgtcttccaggtcctgacaggggaggactggaactccgtgatg
tacaacggcatcatggcctacggtgggccctactaccccggcatgctcgtgtgcatttac
ttcatcatcctcttcgtctgcggcaactacattctgctcaacgtcttcctggccatcgcg
gtggacaacctggccgaggccgagagcctgacctccgcccagaaggccaaggctgaggag
aggaagcgcaggaagatgtccaggggtctcccagacaagccagaggaggaaaagtcggtg
gtagccaagaagctggaccagaagcccaagggggaggggatccccaccactgccaagcta
aaaattgacgaatttgagtccaacgtcaatgaggtgaaggacccctacccctcggctgac
ttccccggggacgatgaagaagatgagcccgagatcccagtgagcccccggccgcggccc
ctggctgagctgcagctgaaagagaaagcggtgcccatcccagaagccagctccttcttc
atcttcagctccaccaataagattcgcgtcctgtgtcaccgcatcgtcaacgccacctgg
ttcaccaacttcatcctgctcttcatcatgctcagcagtgccgcactggccgccgaggac
cccatccgggccgagtccatgaggaaccagatcctcgggtactttgacatcgcgttcacc
tctgtgttcaccgtggagatcatcctgaagatgacgacctacggcgccttcctgcacaaa
ggttccttctgccgcaactacttcaacctcctggacctgctggtggtggctgtgtccctg
gtgtccatgaggcttgagtccagctccatctccgtggtgaagatcctgagggtgctgagg
gtgctccggcccctgcgagccatcaacagagccaaagggctgaagcacgtggtgcagtgc
gtgttcgtggccattcgcaccatcggcaacatcgtcctggtcaccacgctcctgcagttc
atcttcgcctgcatcggggtgcagctcttcaagggcaagttcttccgctgcaccgacctg
tccaagatgacagaggaggaatgcaggggccattactacgtgtacaaggatggggacccc
atgcagatcgagctgcgcccccgcgagtgggtgcacaatgacttccacttcgacaacgtg
ctgtccgccatgatgtccctcttcaccgtctccaccttcgagggctggccgcacctcctg
tacagagccatcgactcgtatgaagaggacaagggcccggtctacaacaaccgcgtggag
atggccatcttcttcatcatctacatcatcatcgtcgctttcttcatgatgaacatcttc
gtgggtttcgtcatcgtcaccttccaggagcagggggagacggaatacaagaactgcgag
ctgaacaagaaccagcgccagtgcgtgcagtatgccctgaaggcccgcccactgaagtgc
tacatccccaagaacccgtaccagtaccaggtgtggtacgtggtcacctcctcctacttc
gagtacctgatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagagcagatgaaccacgtctcagacatcctcaacgtggccttcaccctcatc
ttcaccctggagatgctgctcaagctcgtggccttcaaggccaggggctactttggggac
ccctggaatgtgtttgacttcctgatcgtcattggcagcatcatcgacgtcatcctcagt
gagatcgacaccttcctggcctccagcgggggactgtactgcctcggtggcggctgcggg
aacgttgaccccgatgagagcgcccgcatctccagcgccttcttccgcctcttccgggtc
atgaggctgatcaagctgctgagccgggcagaaggggtgcggaccctgctgtggacgttc
atcaagtccttccaggccctgccctacgtggccctgcttatagtgatgctgttcttcatc
tacgccgtcattggcatgcagatgttcgggaagatcgcgctggtggacgggaccccgatc
aaccggaacaacaacttccagaccttcccccaggctgtgctgctgctcttcaggtgtgcg
acgggggaggcgtggcaggaggtcctgctggccagcagctacggcaagctgtgcgacccg
gagtcggagtacgctccgggcgaggagcactcctgcggcaccaacttcgcctactactac
ttcatcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtcatc
atggacaacttcgactacctgacacgggactggtccatcctgggcccccaccacctggac
gagttcaaggccatctgggctgagtacgaccccgaggccacaggcagaatcaaacacctg
gacgtggtgaccctgctgaggaggatccagcccccgctgggcttcgggaagttctgcccc
caccgggtagcctgtaagcggctcgtgggcatgaacatgcccctgaacagcgatggcaca
gtcaccttcaatgccacgctcttcgccctggtccgcacggccctcaagatcaagacggaa
ggtaacttcgagcaggccaacgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctgctggaccaggtcatcccgcccattggagatgacgaggtgacggtg
ggcaagttctacgccacgttcctcatccaggagcacttccgcaagttcatgaagcgccag
gaggagtactatgggtatcggcccaaaaaggacaccgtgcagatccaggctggattgcgg
accatcgaggaggaggccgcgcccgagatccgcaggaccatctctggagacctgaccgcc
gaggaggagctggagagagccatggtggaggccgccatggaggaagggatattccggagg
accggaggcctgttcggccaagtggacaacttcctggacaggcccaactccctggccccg
gtcatggccaaccagagacccctccagttctcggagatagagatggaggagctggagtcg
cccgtcttcttggaggacttccctccgggtcccagcacccacccgctggctcgtgccaat
accaacaatgccaacgccaacgccaacgccgcccccggcaacagccaccgcagcagcagc
ccagtgcttgccagcgtccactatgacagggagtcccccggagaggcagagccgcccacc
gctgccacctgcgcagccccaggccagccctgcagtaccctgtcaccgcacagcaagtcc
tgtgaggggaagtggagaggacagctgacctggggagccgcgcctggagtccaggcccct
cctgccccctgccagcgccccagggcggagtcccccgtgcctgaggtgaggaggagcccc
atgccagggtctctgcctgaggaagccccccacagcagtagggccccagagagtccctcc
aggtgccaggctccagccacggcccagctgatccaagaggctctgctccgagggggcctg
gactcctgggcggctgacgccggcttcatcaaggcgacaagccaggccctggcagaggcc
tgccggatggaaccagaggaagtggaggtggcagccgcagagctgttgcgaagacgagag
tcctcggagggctcggccagcaccctgggatcccggagcctccagtcctccctgggcagc
cttgaccagcctcagggctcccgggagacactcattccccccaggccttga
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integrated database retrieval system
