KEGG   Desmodus rotundus (common vampire bat): 112321079
Entry
112321079         CDS       T05907                                 
Symbol
PRKAA1
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
  KO
K07198  5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04068  FoxO signaling pathway
dro04140  Autophagy - animal
dro04150  mTOR signaling pathway
dro04151  PI3K-Akt signaling pathway
dro04152  AMPK signaling pathway
dro04211  Longevity regulating pathway
dro04213  Longevity regulating pathway - multiple species
dro04371  Apelin signaling pathway
dro04530  Tight junction
dro04710  Circadian rhythm
dro04714  Thermogenesis
dro04910  Insulin signaling pathway
dro04920  Adipocytokine signaling pathway
dro04921  Oxytocin signaling pathway
dro04922  Glucagon signaling pathway
dro04931  Insulin resistance
dro04932  Non-alcoholic fatty liver disease
dro04936  Alcoholic liver disease
dro05410  Hypertrophic cardiomyopathy
dro05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    112321079 (PRKAA1)
   04068 FoxO signaling pathway
    112321079 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    112321079 (PRKAA1)
   04152 AMPK signaling pathway
    112321079 (PRKAA1)
   04150 mTOR signaling pathway
    112321079 (PRKAA1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112321079 (PRKAA1)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    112321079 (PRKAA1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    112321079 (PRKAA1)
   04922 Glucagon signaling pathway
    112321079 (PRKAA1)
   04920 Adipocytokine signaling pathway
    112321079 (PRKAA1)
   04921 Oxytocin signaling pathway
    112321079 (PRKAA1)
  09149 Aging
   04211 Longevity regulating pathway
    112321079 (PRKAA1)
   04213 Longevity regulating pathway - multiple species
    112321079 (PRKAA1)
  09159 Environmental adaptation
   04710 Circadian rhythm
    112321079 (PRKAA1)
   04714 Thermogenesis
    112321079 (PRKAA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    112321079 (PRKAA1)
   05410 Hypertrophic cardiomyopathy
    112321079 (PRKAA1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112321079 (PRKAA1)
   04932 Non-alcoholic fatty liver disease
    112321079 (PRKAA1)
   04931 Insulin resistance
    112321079 (PRKAA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112321079 (PRKAA1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dro04131]
    112321079 (PRKAA1)
   03029 Mitochondrial biogenesis [BR:dro03029]
    112321079 (PRKAA1)
Enzymes [BR:dro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.31  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
     112321079 (PRKAA1)
Protein kinases [BR:dro01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   112321079 (PRKAA1)
Membrane trafficking [BR:dro04131]
 Autophagy
  Other autophagy associated proteins
   Others
    112321079 (PRKAA1)
Mitochondrial biogenesis [BR:dro03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    112321079 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    112321079 (PRKAA1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr AMPK_alpha_AID AdenylateSensor Kinase-like ABC1 Kdo APH
Other DBs
NCBI-GeneID: 112321079
NCBI-ProteinID: XP_024434296
LinkDB
Position
Unknown
AA seq 475 aa
MFSLTRYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRH
MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP
EVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDP
MKRATVKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYN
RNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPR
ARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLR
VRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQ
RNDSDAEAQGKSSEASLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
NT seq 1428 nt   +upstreamnt  +downstreamnt
atgttttctctcaccaggtaccaggtcatcagtacaccatctgatattttcatggtgatg
gaatatgtctcaggaggagagctatttgattatatctgtaaaaatggaaggctggatgaa
aaagaaagtcgacgtcttttccaacaaatcctctctggcgtggattactgccacaggcac
atggtggtccacagggatctgaaaccggaaaatgtcctgcttgacgcacacatgaatgca
aagatagctgactttggtctttcaaacatgatgtcagatggtgaatttttaagaacaagt
tgtggctcccccaactatgctgcaccagaagtaatttcaggaagattgtatgcaggccca
gaggtagacatatggagcagtggggttatcctctatgctttattatgtggaacccttcca
ttcgatgacgaccatgtgccaaccctttttaagaagatatgtgatggcatcttttacacc
cctcagtatttaaacccttctgtgatcagcctcttgaaacatatgctgcaggtggacccc
atgaagagggccacagtcaaagatatcagggaacatgaatggtttaagcaggatcttcca
aaatatctctttcctgaggatccatcatatagttcaaccatgatcgatgacgaagcctta
aaagaagtgtgtgaaaaatttgagtgctctgaagaggaggtcctcagctgcctttataac
aggaatcaccaggaccctttggcagttgcttaccacctcatcatcgataacaggagaata
atgaatgaggccaaggatttttacttggcgacaagcccacctgattcttttctcgatgat
caccatttgactcggccccatcctgaaagagtgcccttcttggttgctgaaacaccaagg
gcacgccatacccttgatgaattaaatccacagaaatccaaacaccaaggtgtaaggaaa
gcaaaatggcatttgggaattagaagtcagagtcgaccaaatgatatcatggcagaagtc
tgtagagcaattaaacaactggattatgaatggaaggttgtaaacccatactatttgcga
gttcgaagaaagaatcctgtgacaagtacatactccaaaatgagcctacagttataccaa
gtggatagtcgaacgtatttattggatttccgaagtatcgatgacgaaattactgaagcc
aaatcagggactgctacgccacagagatcgggatcagttagcaactatcgatcttgccaa
aggaatgattcagatgctgaggctcaaggaaaatcctctgaagcttctcttacctcatcg
gtgacctcacttgactcttctcctgttgacttaactccaagacctggaagtcacacaata
gaattttttgagatgtgcgcgaatctaattaaaattcttgcacagtaa

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