Desulforamulus ruminis: Desru_0365
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Entry
Desru_0365 CDS
T01518
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
dru
Desulforamulus ruminis
Pathway
dru00290
Valine, leucine and isoleucine biosynthesis
dru00620
Pyruvate metabolism
dru01100
Metabolic pathways
dru01110
Biosynthesis of secondary metabolites
dru01210
2-Oxocarboxylic acid metabolism
dru01230
Biosynthesis of amino acids
Module
dru_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
dru00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Desru_0365
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Desru_0365
Enzymes [BR:
dru01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Desru_0365
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
URO-D
Motif
Other DBs
NCBI-ProteinID:
AEG58662
UniProt:
F6DQT8
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All DBs
Position
362578..364170
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AA seq
530 aa
AA seq
DB search
MSQIGDYKGLIKIYDTSLRDGTQGEGVSLSAEDKMKIARRLDEMGFHYIEGGWPGSNPKD
MEFFARLRQTPLKNALVTAFGSTCRPGVEAARDENLNRLLESGVRAAAIFGKTWDFHVTK
ALNTSLEENLRMVRDSVAYLKQQGLTVFFDGEHFFDGFKANPDYALSVLRAAVEGGADAV
VLCDTNGGTLPHELQSVVARVKQELPGVELGIHAHNDGEMAVANTIVAVQAGVTQVQGTV
NGLGERCGNANLCSILPNLTLKLGYETIPRENFAFLTELSRFVYEVANLNPVNNQPFVGE
SAFAHKGGIHVSALLKEPGTYEHMPPEWVGNTRRVLMSELSGLSNLLYKYKELHLDKSSP
EGRRVLEQLKNMEHRGYQFEAAEGSLEIMLRKAVNGYREPFQLESMRLILEMREDRPIQS
EAVIKLRVGEEVVHTAAEGNGPVNALDNALRKALETVYPEVPGLRLLDYKVRVLEEKAGT
EAQVRVLIETGNGKKTWGTVGVSTNIIEASWQALADGMAYGLLKDENNKA
NT seq
1593 nt
NT seq
+upstream
nt +downstream
nt
gtgagtcaaattggggattataagggtctaatcaaaatttacgacacatccctgagggac
gggacccagggagaaggggtcagcctttcggcggaagataaaatgaaaattgcccggcgt
ctggatgaaatgggcttccactatattgaagggggatggcccggctccaatcccaaggat
atggaattctttgcccgcctgcggcagacgcctttaaagaatgccctggtcaccgccttt
ggcagcacctgccgcccgggggtggaagcggcccgggatgaaaacctcaaccggctgctg
gaatccggggtgcgggctgcggctatatttggcaaaacctgggatttccatgtcaccaag
gccctgaataccagtctggaagagaacctccgcatggtgcgggactcggtggcttatctt
aagcaacagggcctcacggtctttttcgacggagagcacttctttgacggctttaaagcc
aatccggactatgccctgtcggtcctgcgggccgccgtggagggaggggccgacgcggtg
gtgttgtgcgacaccaacggcggtactctgccccacgagctccagtcggtggttgcccgg
gtaaagcaggaactgccgggggtggaattgggcattcatgcccataacgacggggaaatg
gcggtggccaacaccattgtggcggtccaggccggagtaacccaggtgcagggcaccgtg
aacggcctgggcgaacgctgcggcaatgccaatttatgctccattctgccgaacctgacg
ttgaaactggggtatgagaccatcccccgggaaaattttgctttcctgacggagctttcc
cgctttgtctacgaggtggccaacttgaacccggtgaataaccagccctttgtgggagag
agcgcttttgcccacaagggggggattcatgtcagcgccctgctgaaggaaccgggaacc
tacgagcatatgcctccggagtgggtgggcaatacccgccgggtgctcatgtccgaattg
tccggtctgtccaacctgctttataaatacaaggaactgcacctggacaaaagcagtccc
gagggacgcagagtactggaacagcttaaaaacatggaacaccggggctaccagtttgag
gctgccgagggttccttggaaattatgctgagaaaggctgtaaacggctaccgggagccc
ttccaactggaaagcatgcggcttattctagagatgcgggaagaccggcccattcaatcg
gaggccgtgattaagctaagagtcggggaagaagtggtgcacaccgccgccgaaggcaac
ggcccggtgaacgccctggacaacgccctgcgcaaggcactggaaaccgtttatcccgag
gttcccgggctgcggctgttggactacaaggtccgggtactggaagaaaaggccggcacc
gaagcccaggtacgggtgcttatcgaaaccggaaacggcaaaaaaacctggggaacggtg
ggtgtgtccaccaatatcattgaagccagttggcaggctttggccgacggcatggcctac
ggcctgctgaaagatgagaacaataaggcttaa
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