Enteropathogenic Escherichia coli (EPEC) was the first pathotype of E. coli identified in the 1940s, and remains a common cause of infantile diarrhea in developing countries. EPEC and EHEC [DS:H00277] strains are characterized by the type III secretion system and its cognate effectors encoded in the locus of enterocyte effacement (LEE), but EPEC does not release diffusible toxins.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
Gastroenteritis or colitis of infectious origin
Bacterial intestinal infections
1A03 Intestinal infections due to Escherichia coli
H00278 Enteropathogenic Escherichia coli (EPEC) infection
Pathway-based classification of diseases [BR:br08402]
Signal transduction
nt06516 TNF signaling
H00278 Enteropathogenic Escherichia coli (EPEC) infection
Cellular process
nt06524 Apoptosis
H00278 Enteropathogenic Escherichia coli (EPEC) infection
Immune system
nt06517 TLR signaling
H00278 Enteropathogenic Escherichia coli (EPEC) infection
nt06521 NLR signaling
H00278 Enteropathogenic Escherichia coli (EPEC) infection
Genome-based classification of infectious diseases [BR:br08401]
Bacterial infections
Infections caused by enterobacteria
H00278 Enteropathogenic Escherichia coli (EPEC) infection
