KEGG   DISEASE: Actinomycetoma
Entry
H01451                      Disease                                
Name
Actinomycetoma
Description
Mycetoma is an infectious disease of skin and subcutaneous tissue. It can be caused by either bacteria (actinomycetoma) or fungi (eumycetoma [DS:H02385] ). It is endemic in tropical and subtropical regions, predominating between latitudes 15 degrees south and 30 degrees north, called mycetoma belt. Actinomycetoma is most commonly found in Latin America. Although Nocardia brasiliensis, Actinomadura madurae, Actinomadura pelletieri and Streptomyces somaliensis are the common causative organisms of actinomycetoma, the distribution of them shows strong geographic variation. The primary niche of these microorganisms is suggested to be the soil. The infection is thought to start subcutaneously after traumatic inoculation of these microorganisms.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C43  Actinomycetoma
    H01451  Actinomycetoma
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by actinobacteria
   H01451  Actinomycetoma
Pathogen
Nocardia brasiliensis [GN:nbr]
Nocardiopsis dassonvillei [GN:nda]
Actinomadura madurae [GN:amaz]
Actinomadura pelletieri
Streptomyces somaliensis
Comment
See also H02385 Eumycetoma and H00345 Nocardiosis.
Other DBs
ICD-11: 1C43
ICD-10: B47.1
MeSH: D008271
Reference
  Authors
Salinas-Carmona MC
  Title
Nocardia brasiliensis: from microbe to human and experimental infections.
  Journal
Microbes Infect 2:1373-81 (2000)
DOI:10.1016/S1286-4579(00)01291-0
Reference
  Authors
Zijlstra EE, van de Sande WWJ, Welsh O, Mahgoub ES, Goodfellow M, Fahal AH
  Title
Mycetoma: a unique neglected tropical disease.
  Journal
Lancet Infect Dis 16:100-112 (2016)
DOI:10.1016/S1473-3099(15)00359-X
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