KEGG   DISEASE: 大型血管炎
エントリ  
H01465                                                             
名称    
大型血管炎
  下位グループ
巨細胞性動脈炎 (GCA) [DS:H01698]
高安動脈炎 (TAK)
概要    
Large vessel vasculitis (LVV) covers a spectrum of primary vasculitides predominantly affecting the aorta and its major branches. Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are the two main subtypes. GCA is the most common vasculitis affecting adults aged 50 years or more, while TAK is a rare vasculitis that affects younger individuals mainly under 40 years. Clinical presentations vary from asymptomatic to significant systemic symptoms such as fever, weight loss, and symptoms that result from aortitis and high inflammatory markers; C-reactive protein (CRP); and erythrocyte sedimentation rate (ESR) levels. Glucocorticoids are the mainstay of therapy of LVV. Patients may develop predictable adverse effects from long-term glucocorticoid use.
階層分類  
ヒト疾患 [BR:jp08402]
 循環器系疾患
  脈管疾患
   H01465  大型血管炎
ICD-11 による疾患分類 [BR:jp08403]
 04 免疫系の疾患
  非器官特異的全身性自己免疫疾患
   4A44  血管炎
    H01465  大型血管炎
特定疾患 (難病) [jp08407.html]
 H01465
治療薬   
デキサメタゾン [DR:D00292]
デキサメタゾンリン酸エステルナトリウム [DR:D00975]
ベタメタゾンリン酸エステルナトリウム [DR:D00972]
トリアムシノロンアセトニド [DR:D00983]
ヒドロコルチゾン [DR:D00088]
トリアムシノロン [DR:D00385]
ベタメタゾン [DR:D00244]
プレドニゾロン [DR:D00472]
メチルプレドニゾロン [DR:D00407]
メチルプレドニゾロンコハク酸エステルナトリウム [DR:D00751]
メチルプレドニゾロン酢酸エステル [DR:D00979]
アザチオプリン [DR:D00238]
シクロホスファミド水和物 [DR:D00287]
トシリズマブ [DR:D02596]
リンク   
ICD-11: 4A44.Y
ICD-10: M31.4 M31.6
MeSH: D013700 D013625
文献    
  著者
Chatterjee S, Flamm SD, Tan CD, Rodriguez ER
  タイトル
Clinical diagnosis and management of large vessel vasculitis: giant cell arteritis.
  雑誌
Curr Cardiol Rep 16:498 (2014)
DOI:10.1007/s11886-014-0498-z
文献    
PMID:23949338 (description, drug)
  著者
Al-Homood IA
  タイトル
Tocilizumab: a new therapy for large vessel vasculitis.
  雑誌
Clin Exp Med 14:355-60 (2014)
DOI:10.1007/s10238-013-0254-5
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