KEGG   DISEASE: リウマチ性多発筋痛症
エントリ  
H01606                                                             
名称    
リウマチ性多発筋痛症
概要    
Polymyalgia rheumatica (PMR) is a relatively common inflammatory rheumatic disease in people older than 50 years of age. PMR is a clinical condition defined as the presence of inflammatory pain in the limb girdles. Range of motion is decreased at the shoulder and pelvic girdles, and the neck and hip girdle may also be involved. These symptoms often persist for at least 1 month and are combined with incapacitating morning stiffness, a decline in general health, and an elevated acute-phase response. Onset of PMR symptoms may be acute or gradual. It is known that PMR patients share many pathogenetic features with giant cell arteritis (GCA). Despite the similarities in age of onset and some of the clinical manifestations, the relationship between GCA and PMR is not yet clearly established. One-third of PMR patients have systemic manifestations such as low-grade fever, malaise, and anorexia, but these are often milder than systemic symptoms in GCA patients. PMR is a benign and highly steroid-sensitive disease that should resolve fully with low-dose glucocorticoid therapy for 12-24 months, although one or two relapses may occur. The diagnosis of PMR is made primarily on clinical grounds and is bolstered by laboratory evidence of an acute-phase reaction. There is no single diagnostic test for PMR, but sets of diagnostic and classification criteria have been suggested by several groups of investigators.
カテゴリ  
筋骨格疾患
階層分類  
ヒト疾患 [BR:jp08402]
 筋骨格疾患
  その他の筋骨格疾患
   H01606  リウマチ性多発筋痛症
ICD-11 による疾患分類 [BR:jp08403]
 15 筋骨格系・結合組織の疾患
  関節症
   炎症性関節症
    FA22  リウマチ性多発筋痛症
     H01606  リウマチ性多発筋痛症
治療薬   
デキサメタゾン [DR:D00292]
デキサメタゾンリン酸エステルナトリウム [DR:D00975]
ベタメタゾンリン酸エステルナトリウム [DR:D00972]
ヒドロコルチゾンコハク酸エステルナトリウム [DR:D00978]
トリアムシノロン [DR:D00385]
ベタメタゾン [DR:D00244]
プレドニゾロン [DR:D00472]
プレドニゾロンコハク酸エステルナトリウム [DR:D01239]
メチルプレドニゾロン [DR:D00407]
メチルプレドニゾロン酢酸エステル [DR:D00979]
リンク   
ICD-11: FA22
ICD-10: M35.3
MeSH: D011111
文献    
  著者
Ameer F, McNeil J
  タイトル
Polymyalgia rheumatica: clinical update.
  雑誌
Aust Fam Physician 43:373-6 (2014)
文献    
  著者
De Bandt M
  タイトル
Current diagnosis and treatment of polymyalgia rheumatica.
  雑誌
Joint Bone Spine 81:203-8 (2014)
DOI:10.1016/j.jbspin.2013.12.010
文献    
  著者
Nesher G
  タイトル
Polymyalgia rheumatica--diagnosis and classification.
  雑誌
J Autoimmun 48-49:76-8 (2014)
DOI:10.1016/j.jaut.2014.01.016
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