KEGG   DISEASE: シデナム舞踏病
エントリ  
H01924                                                             
名称    
シデナム舞踏病;
小舞踏病
概要    
Sydenham chorea is a disabling pediatric hyperkinetic and neuropsychiatric disorder following streptococcal infection. Sydenham chorea occurs in approximately 10% of acute rheumatic fever and is one of its major manifestations. The disease may last for weeks or months, with a high risk of recurrence. The common features of rheumatic fever include sore throats due to streptococcal infections, rashes, pains in the limbs, and subcutaneous nodules, and this form of chorea typically presents, after varying intervals, with twitching of the mouth and limbs, shrugging of the shoulders, and clumsy gait. Those with this form of chorea are less likely to have severe cardiac or rheumatologic complications. The pathogenesis has been considered to be an autoantibody-mediated basal ganglia dysfunction. Anti-inflammatory treatments such as steroids, plasmapheresis and intravenous immunoglobulin treatment are effective.
カテゴリ  
免疫系疾患; 神経系疾患
階層分類  
ヒト疾患 [BR:jp08402]
 免疫系疾患
  その他の免疫系疾患
   H01924  シデナム舞踏病
 神経系疾患
  その他の神経系および感覚器系疾患
   H01924  シデナム舞踏病
ICD-11 による疾患分類 [BR:jp08403]
 01 感染症・寄生虫症
  ブドウ球菌またはレンサ球菌感染症
   急性リウマチ熱
    1B42  リウマチ性舞踏病
     H01924  シデナム舞踏病
環境要因  
Group A beta-haemolytic streptococcal infections
治療薬   
デキサメタゾン [DR:D00292]
デキサメタゾンリン酸エステルナトリウム [DR:D00975]
ベタメタゾンリン酸エステルナトリウム [DR:D00972]
トリアムシノロンアセトニド [DR:D00983]
ヒドロコルチゾン [DR:D00088]
ヒドロコルチゾンコハク酸エステルナトリウム [DR:D00978]
コルチゾン酢酸エステル [DR:D00973]
トリアムシノロン [DR:D00385]
ベタメタゾン [DR:D00244]
プレドニゾロン [DR:D00472]
メチルプレドニゾロン [DR:D00407]
メチルプレドニゾロン酢酸エステル [DR:D00979]
コメント  
See also H01424 Group A streptococcal pharyngitis.
リンク   
ICD-11: 1B42
ICD-10: I02
MeSH: D002819
文献    
  著者
Gordon N
  タイトル
Sydenham's chorea, and its complications affecting the nervous system.
  雑誌
Brain Dev 31:11-4 (2009)
DOI:10.1016/j.braindev.2008.05.001
文献    
PMID:24073196 (drug)
  著者
Ben-Pazi H, Stoner JA, Cunningham MW
  タイトル
Dopamine receptor autoantibodies correlate with symptoms in Sydenham's chorea.
  雑誌
PLoS One 8:e73516 (2013)
DOI:10.1371/journal.pone.0073516
文献    
PMID:15730904 (drug)
  著者
Barash J, Margalith D, Matitiau A
  タイトル
Corticosteroid treatment in patients with Sydenham's chorea.
  雑誌
Pediatr Neurol 32:205-7 (2005)
DOI:10.1016/j.pediatrneurol.2004.09.012
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