| 概要 |
Leukoencephalopathy without lacunae, adult-onset (LUCAO) is a novel familial cerebral small vessel disease characterized by the association of a hippocampal-type episodic memory defect and diffuse vascular leukoencephalopathy. End-truncating mutations in LAMB1 have been identified in affected individuals. LAMB1 encodes laminin B1, one of the extracellular matrix (ECM) proteins that makes up the basement membrane.
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| 著者 |
Aloui C, Herve D, Marenne G, Savenier F, Le Guennec K, Bergametti F, Verdura E, Ludwig TE, Lebenberg J, Jabeur W, Morel H, Coste T, Demarquay G, Bachoumas P, Cogez J, Mathey G, Bernard E, Chabriat H, Genin E, Tournier-Lasserve E |
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| 著者 |
Morel H, Bailly L, Urbanczyk C, Herve D, Berroir S, Le Bouc R, Levy R, Meyer M, Aloui C, Tournier-Lasserve E, Mathey G |
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