Drosophila simulans: Dsimw501_GD10606 Help Entry Dsimw501_GD10606  CDS       T01065                                  Symbol Dsim_GD10606 Name (GenBank) uncharacterized protein   KO K04962   ryanodine receptor 2 Organism dsi  Drosophila simulans Brite KEGG Orthology (KO) [BR:dsi00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:dsi04040]     Dsimw501_GD10606 (Dsim_GD10606)    04990 Domain-containing proteins not elsewhere classified [BR:dsi04990]     Dsimw501_GD10606 (Dsim_GD10606) Ion channels [BR:dsi04040]  Voltage-gated cation channels   Ryanodine receptor    Dsimw501_GD10606 (Dsim_GD10606) Domain-containing proteins not elsewhere classified [BR:dsi04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    Dsimw501_GD10606 (Dsim_GD10606) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-ProteinID:  KMY92353 UniProt:  A0A0J9R8D8 LinkDB All DBs Position 2R:5556863..5584438 Genome browser AA seq 5117 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVTLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS QCVFVIEQALSVRALQELVTAAGSETDSRLGKGTGSGHRTLLYGNAILLRHHNSDMYLAC LSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLH TTKENEQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWG REAGQNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSN ELILVKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLW LSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFI TALETLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDL FQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGR VDGSSMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYS FGFDGAYLWTGGRKTLVVDALPEEPFIRKGDVVGVAIDLSVPIITFTFNGVKVRGSFRDF NLDGMFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFGN LSKNVLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSW GEHRDDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMDKPPARIRPVRL PNEIFMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSE NHRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFA GFRTYRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNEE KVYGGVSESFGKQCGPGDIVGVFLDLADHTISFSLNGELLMDALGGETTFADVTAEGVGF VPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENT EEMPDCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMGEFISEQEKA RRWDEIKNRQYRLMREAEIAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEA DHMMRGPNRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPF KFFSKKSRDQSREKMGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPV PQGPKQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQY HLHSREFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGM FVGCFVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLP LSAAVLPTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPV SMLALHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQL LYAIRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKELYSEEEMQHS LRSLVTESVRPQLRMTEITEPIPDIDQLYSPKFPLEVVRQFVMEALKDAVEINQVHNRDP IGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWDQAFEREGKDEHRKGLLT MKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRYIEIKQSDLPSA VAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDSLMQKVSLNAL QEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVEEPEKKTPEEVFRKVLIKTIV SWAEESQIENPKLVREMFSLLLRQYDTVGELVRALEKTYVINTRARDDVAEMWVGLSQIR ALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQS DAPTQTEGAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILL ARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSELVEKGYPDLG WDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGEGLFRAIVEA NRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNFYCTLVDLLGRC APDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEKPKSDMPSGLLP NNKQSIVLFLERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDMALAMNRYIGN SILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDFLVALTSQMQP AMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYGASSDEEKRLTM LLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYGRQMGAPDQPQ YMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTYGDIRSDNDRKHPRLKPY NMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVPLNHRGSTRRQSKPQINEFQNEGS PFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVIHPQLVPYDLL TDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGVTQAAVELRFSYSLLEKLIQY LDRATINMKLLKPSTTFSRRSSFKTATRDIKFFSKVVLPLMEKYFSTHRNYFIAIATATN NIGAASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGIDARTLTKNCPE FIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVVLPVLTAMFDH LAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHRPALGSCLGAY SSCFPVAFLEPHLNKHNQYSLLNRIADHSLEAQDIMVKMESCMPNLETILAEVDQFVESD KTYNDAPHIIDVILPLLCAYLPFWWSQGPDNVSPTSGNHVTMVTADHMNPLLRNVLKMIK KNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMLHKEDSMRGFIK SATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEAEELYNHVAEI FNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKVKKKKKNRDKK RDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEYDVIEFARNQLT LPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNSNEKGKDKTQETVDRIVAMAK VLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARSYYEQW LQEENVGQEVMVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGAMTERSGALQE DLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQKLLFHQARLSNRG VAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKKDVGFFTSIAG LMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLEWQ NYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQ VFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQ KDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLADLIESPSFHEV DMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRAFVEHFHEPSKEIG FNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRIERVYFEIKDS NIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMATDDGGGN VKRDTAYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANIKHQIGVMQTKSIP ELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEPVVEEETFGRALPP LPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSPEDGAAASGELVEGE PHQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAEAKKSSSAPQETPAVHQIDF SQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFTEEADSSAEEELILGSGSG GGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACLHSLVSLAMLI AYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAKSFPVNYWDKF VKKKVRQKYSETYDFDSISNLLGMEKSTFAAQESEETGIFKYIMNIDWRYQVWKAGVTFT DNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLT IIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDG DDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKD FFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVGD CFRKQYEDELSGGGGGG NT seq 15354 nt NT seq  +upstreamnt  +downstreamnt atggctgaggcggagggaggctccgagcaggatgatgtttcattcctgagaacggaggac atggtcacgctctcctgcacggcgacgggggagcgtgtctgcttggccgccgagggattt ggcaaccggcactgctttctcgagaacattgccgacaagaacgtgccgccggatctttcg caatgtgtcttcgtcatcgaacaggcgctgtccgtgcgagctttgcaggagttggtgacg gcggccggatccgagactgatagtcgacttggcaaaggcacaggatcgggacacaggaca ttgctctatggcaatgccattttgctgcgacatcacaacagtgatatgtacttggcctgt ctgtccacctcgtcgtcgaacgacaagctgtccttcgacgtgggcctgcaggagcacagc cagggagaggcttgttggtggaccgttcatccggcgagcaagcagcgctctgagggcgag aaggtgcgcgtcggagatgacctgatcctggtgtcggtggccaccgaacgttatttgcat acgaccaaggagaacgagcagtccattgtaaacgccagctttcacgtgacccactggtcc gtgcagccctacggcacgggcatctctaggatgaagtacgtgggctatgtctttggcggc gatgtgctgcgcttcttccatggcggcgacgagtgcctgaccataccgagtacatggggt cgtgaggcgggacaaaatattgttatttacgagggcggcgtggtcatggcacaggcgagg tccctgtggcgcctggaactcgcacgaaccaagtggactggtggctttatcaactggtac cacccgatgcgcattcgccacataaccactggacgctacttgggcgtcaacgacagcaac gaactgattctggttaagaaggaggaggcttcgattgccacgacgactttctgcctgcgg caggaaaaggacgacgagaaaaaggtgctggaggacaaggacctggaggtgatcggctcg ccgatcatcaagtacggcgacactaccgtcatcgtccagcactgcgagactagcttgtgg ctcagctacaagagctacgagacgaagaagaagggcgtaggaaaggtggaggagaagcag gccatcctgcacgaggagggcaagatggacgattgcctcgacttctcgcgctcccaggag gaggagtccaagacggctcgtgtcatccgcaagtgcagcagcctcttcacccagtttatt acggccttggaaacactgcagtcaaatcgccgacactccattttcttccaaaaggtcaac ctcaacgagatggtcatgtgcctggaggacttgatcaactacttttcgcaacccgaagac gatatggagcacgaggagaaacagaatagattccgtgccctgcgcaaccgacaggatctg ttccaggaggagggcgtgctcaatctgatcctggaggccattgacaagatcaacataatc acctcgcagggcttcctcgccagcttcctggccggcgacgagaccggccagagctgggat ctcatttccacctatctgtaccaactcttggccgccatcatcaagggcaaccacacgaac tgcgcccagttcgcgaacagcaaccgactcaactggctattctcgcgtctcggttcccag gcctccagcgagggttccggcatgttagacgtactccactgcgtgctgatcgattcgccc gaggcgctgaacatgatgcgggatgagcacatcaaggtgatcatctcgctgctggagaag cacggcagggacccgaaagtcctggacgttctgtgttccctgtgcgtgggtaatggagtg gcggtgcgatcctcccaaaacaatatttgcgactttttgctgccaggcaagaacctgttg ctacagacgctcctggtggaccacgtggccagcatccgaccgaacatcttcgtgggccgc gtggacggctcttccatgtaccagaagtggtacttcgaggtgaccatggatcacatcgaa cagaccacgcacatgatgccccacctgcgcattggctgggctaatacttccgggtatgta ccgtatcccggaggcggcaagaagtggggtggcaatggagtaggcgatgacctgtactcc tttggatttgatggtgcctatctttggaccggtggccgcaaaacactagtggtggacgcg ctgcccgaggagccctttatccggaaaggcgatgttgttggcgttgccattgatctttct gtgcccatcatcacgtttacatttaacggagtaaaagtgcgcggtagctttagggacttc aacctggatggaatgttctttcccgtgatgagttgctcatcaaaactaagctgtcgcttc cttttcggaggggatcatggtcgtttgaagttcgccccgcccatgggattctctgcactc gtgcagtgtctcatgccgcagcagatcctcagtctggatccctgcttctactttggtaat cttagcaagaatgttttggccggaccttggcttattgaggacgacactgcttttgttccg aaacccgtggataccacgggtgtgacattgccaagttctgtggaccaaatcaaggagaag ctggcggagaatatccacgagatgtgggctctgaacaaaatcgaggcgggctggtcgtgg ggcgagcaccgtgatgactaccaccgcatccatccctgcctcacccatttcgagaagctt ccggcggcggagaagcgatacgacaatcaactggctgtgcaaacgctaaagacgattatc tcactgggatactacataaccatggacaagccaccagcacgcattcgcccagtgcgcctg cccaacgagatcttcatgcagggcaatggctacaagccggctccacttgacctaagcgcc gtaacactgacccccaagttggaggagctagtggaccagctggccgaaaacacccacaat ctatgggcacgggaacgcatccagcagggttggacatatggactgaacgaggatagtgaa aaccacaggagtccacatttggtgccctatgccaaggtggacgaggctatcaagaaggcg aacagggacacagcgtcggagacagtgcgaacgctcctggtttacggatatgtgttggat cctccgacgggcgagggaacggaggcacttctggccgaggcacaacgcctcaagttcgcc ggattccggacttacagagtggagcgcaactatgccgtgacatcgggcaagtggtacttc gaattcgaggtcctcacgtccggacccatgcgagtgggttgggcccgggccgattgctat ccgggagcgatgctgggcagcgaggacaccagttgggccttcgatggacacaatgaagag aaagtctacggtggcgtcagtgaatcctttggtaaacagtgcggccccggggacatagtc ggcgtctttctagacctggccgaccacacaattagcttctcgttgaacggagaactcctg atggacgcgctgggcggcgagacgacctttgccgacgtaaccgccgagggggtgggcttc gtgcccgcctgcaccctgggagtgggccagaaggcgcgcctcatctacggccaggacgtg gactcactcaagttcttcaccacctgtggcctgcaagagggatacgagcccttctgcgtg aacatgcgtcgcccggttacacactggtacaccaaggaccagcccattttcgagaacacc gaggagatgcccgactgccgcatcgatgtcactcggattcccggcggcgccgacactccg ccacacttaaaaatctcgcacaacaccttcgagaccatggagaaggccaactgggagttc ctgcgtctatccctgcccgtgacctgcatgggtgagttcatcagcgagcaggagaaggcc agacgctgggacgagattaagaaccggcagtaccgactcatgcgcgaggcggagattgct gcccagatgcaggtccagacacaggccgcccacatggaccacatgctgaaaggtggcttc aatatgaacgacatcaagggcttgacccgtaatttcgatgagcacgcggatgctgaggca gatcacatgatgcgaggacccaaccgcccgcctcgcaagggatctctcacccgcaacata actttcgaaacagacatgtctgccgccctggacgagatgcagcgatccacgtccgtgctg gacatgaacggcctgggcgaagagatggatgacaagaagaagcgtggccgcagccccttc aagttcttctcgaagaagtcgcgtgaccagagtcgcgaaaagatgggtgctcgcaccctg gacacctctctggagcgtcgaaataccgttgctcatggacggaacgtggttaaccagcag atgaccacacgagctccaactctgcggttaaataatgccgaaatccctcccagccctgtg ccccagggaccaaaacagttgagtggctcgaatcttggccaacagccggtggaaacttcg ggtgacgagatgttcgatgccgagtgcctcaagttgatcaacgagtatttctatggagta agaatctttcccggtcaggatcccacgcacgtgtacgtcggttgggtgaccacgcagtat cacctgcacagccgtgagtttaacaagaacaaggttcgccgtgggtcagtctacatcgag gatgactacgagatggccatcgaacggattgaccgacagagttgctatgtggttcgagcg gacgagctcttcaacgaggttacccaggatgcctcaggcaagggagcctcccagggcatg ttcgttggctgcttcgtggacacagccactggcatcatccgctttacttgcgagggcaag gacacctctcaccgctggatgatggagccagacaccaagctcttcccggccattttcgtg gaggccaccagcaaggagatcctccagatcgagttgggacgtacccctaccacattgccc ctttcagcggctgtactgcccaccagtgacaagcatataaatccacagtccccgccgcgt ctgaaggtccagtgcctgcgtccacatcagtgggctagagttccaaataccgcactccag gtgcatgcgcttaaactatccgacgtgaggggttggtccatgttgtgcgaggaccccgtg tccatgctggccctgcacatcccagaggaggatcgctgtatagatattctggagctcatc gagatggacaagcttttgtccttccatgcccacagtctaacgctctatgcggctctttgt taccaatccaattacagagctgcccatgccctgtgccagcatgtggaccagaagcagctg ctctacgccatccggtcggagtacatgagtggaccactgcggcagggcttctacgacctg cttattgccctgcatctggagtctcatgccacaaccatggaggtgtgcaagaacgagtac atcacaccgctgggagccgaactcaaggaactgtactccgaagaggagatgcagcactca ctgagatccctggttacggagtcagtgcgtccgcagctgcggatgacggagatcaccgaa ccgatccccgacatcgaccaattgtactccccgaagttccccctagaagtagtcaggcag tttgtcatggaggcgctgaaggatgccgtcgagatcaatcaggtgcacaaccgcgatccc atcggctggaccaacgagaacctcttcctccctctaatcaagctcacagaccgactactc ttggtcggcgtcctgaccgacgaagatgtccagcggctgttggtcatgatcgacccggag acctgggaccaagcctttgagagagagggtaaggatgagcaccgcaagggcttgctcacc atgaagatggccgagggcgccaagctgcagatgtgctacctgctgcaccatctctacgac acccagctgcgccaccgagtggagagcatcatcgcgttctcccacgacttcgtgggcgac ctgcagaccgatcagttgcgacgttatatcgagatcaagcaatccgatttgcccagtgct gttgcggccaaaaagactaaagagttccgctgtccgccgcgggagcagatgaaccagatt ctctgcttcaagaacctcgaacccgatgaccaggacaactgcacctgtggccttgagttg cgcggacgcctgggcgatttccacgattccctcatgcaaaaggtgtcgctcaatgctctc caggagccggatggcgtcgagggcacagcgatcgaggaggtgaagacaggacccatcacg aagatctacaactttatcaacaccgtcaaggagctggaggagggccccaaggaggtggag gagccggagaagaagacaccagaggaggtgttccgcaaagtgctcattaagacgatcgtc agctgggccgaggagtcacagatcgagaatcccaagctggtgcgcgagatgttcagtctg ctgctgcggcagtacgacaccgtcggagaattggttcgtgccctggagaagacgtacgtg ataaacacccgagcccgcgacgacgtggcagagatgtgggtgggcctcagccagattcgc gccctgctgcccgtccaaatgagccaggaagaggaggaactgatgcgcaagcggctgtgg aagctggttaacaacgccaccttcttccagcacccggaccttatacgcatcctgcgcgtc cacgagaacgtaatggcagtgatgatgaacacactcggacggagggcacaggcgcaaagc gatgcgcccacccagacggaaggagccgaaggagctccgtccaaggagaaggacacctcc cacgaaatggtggtagcttgctgccgattcctctgctacttctgtcgcactggtcgccaa aaccaaaaggccatgtttgatcacttcgactttctgctggacaacgccaacatcctgctg gcacggcccagcctgcgaggatccacgcccctcgatgtggcatactcgagtttgatggag aacacagaattggctctggccctgagggaacactatctggagaagatcgccgtctacctc tcgcggtgcggactgcagagcaactcggagctcgtggagaagggctatccggatctgggc tgggatcccgtcgaaggtgagcggtacctggacttcctgcgctattgcgtttgggtcaac ggcgagagcgtcgaggagaatgcgaaccttgtcattcgacttcttatccgtcgtccggaa tgcttgggaccggctctaagaggagaaggagaaggtctgttccgcgccatcgtcgaggct aatcgcatgtcggagcgcatctcggaccgctgcaagatgcaggacgaggccgagggcacc attgccgggctaaacttcacacatcctctgccggagggcgaggaggacgaggactacatc gataccggtgccgccattctgaacttctactgcaccctggtggacctactgggccgctgt gctccggacgcttcggtcatcgagcagggcaagaacgagtccctgagggctagagctatt ctgagatctctggtgccactggaggatttgcagggggtgctcagcctgaaattcaccctc tcgcagacggcccccggcgaggagaagcccaaatcggacatgccgtccggcctgctgccc aacaacaagcagagcatcgtgctcttcctggagcgcgtctacggcatcgaggcacaggac ctcttctaccgcctgctggaggacgccttcctgccggatctccgcaccgccaccattctg gacaagagcgatggatccgagagcgacatggcgctggccatgaaccgctacatcggcaac tcgatcctgccgctgctcatcaagcactccaagttctacaacgaggccgagaactacgcg agcctcttggatgccactttgcacacggtctaccggctgtccaagaaccgtatgctgacc aaggggcagcgcgaggccgtttccgacttcctggtggccctcacatcccaaatgcaacct gccatgctgctcaagctgctgcgcaagttgactgtggatgtgtccaagctgtctgagtac accaccgtggccctccggcttctcaccctgcacttcgatcgctgcgccaaatactacggc tcaactcaaggccagggctcctatggagcctcatcggacgaggagaagcgcctgacgatg ctgctgttctcgaacatttttgactcgctcagcaacatggactatgacccggaactgttc ggtaaggcactgccctgcctgatcgccatcggctgcgccctgccaccggactacagtctg tccaagaacacggacgaggactactacggccgccagatgggcgcaccggatcagccacaa tacatgcccaatccgatcgacaccaacaacgtgcacctggacaacgatctcaactcgctg gtccagaagttcagcgagcactaccacgatgcgtgggccagtcggcggttggaaggtggc tggacctacggagacatccgatccgataatgatcgcaaacatcctcgcctgaagccctac aacatgctcagtgaatacgaacgcgagcggtaccgcgatccggtgcgggagtgcctaaag ggtctgctggccatcggctggaccgtggagcactccgaggtggaggtgccgctgaatcat cgcggatcgacgcggcgtcagtcgaagccccaaattaacgaattccagaacgagggcagc ccgttcaactacaacccgcacccggtggacatgagcaacctgaccctgagcagggagatg cagaacatggccgagcgcctggcggagaattcccacgacatctgggccaagaagaagaac gaggagctcaacggctgcggtggcgttatccatccacaactggtgccatacgatcttctg accgacaaggagaagaagaaggatcgcgagcgctcgcaggagttcctcaagtacatgcag taccagggctacaaactgcacaagccatcaaagggaggagctgtggaggagggcggtgta acccaggctgccgttgaactgcgcttctcgtactccctactggagaagctcattcagtat ctggatcgagccaccatcaacatgaaactgctgaagccatcgaccacgtttagtcgccgc tcatccttcaagacggccacccgggacatcaagttcttctcgaaggtggtgctgcctctg atggagaagtacttctcaacgcatcgcaactacttcatcgccattgccacggcaaccaat aatattggagcggcctcgctcaaggagaaggaaatggtggcctcgatcttctgcaagctg gccgctctactgcgtaaccggctgagtgcatttggaccggatgtccgcatcacagtacgg tgcctccaggtcctggtcaagggcatcgatgcacgcaccctgaccaagaattgtcccgag ttcattcgcacctccatgctgaccttcttcaaccagacatccgatgacttgggtaacacg atccttaacctgcaggatggcaagtacagtcacctgagaggcactcacctgaagacctcc acatcgttgggatatgtaaaccaggtggtcttgccggtgcttaccgccatgtttgatcat ctggcagcctgcgactatggcagtgatttgcttctcgacgagatccaggtggcttcctac aagatcctcgctgcactgtatcatttgggtaccgatggcaccctgacgcatgacaggaag tatcttaagaccgagattgagaggcatagacccgctctgggttcctgtctgggagcttac agctcctgctttccggtggccttcttggagccccaccttaacaagcacaaccagtactcg ctgctcaaccgtattgcggatcactcgctggaggcgcaggacattatggtcaagatggag agctgtatgccaaatctagagaccattcttgccgaagtcgaccagtttgtggagtcggac aagacatacaacgatgcgcctcatattatcgacgtgatcctgccgctgctttgcgcctat ctaccgttttggtggtcccagggaccggataatgtcagtcccaccagtggcaaccacgtg accatggtcacagccgatcacatgaatccgttgctgcgaaatgtgctcaaaatgatcaag aagaacattggcaacgataatgccccatggatgactcgcattgccgcctatacgcagcag attatcatcaatacgtcggaggagcttctcaaggatccattcttgccgctggcggagcgg gtgaagaagcgcactgagaacatgctgcacaaggaggacagcatgcgaggattcatcaag tcggccacggacgacacttcgcaggtggagacgcagctgcaggaggactggaatcttcta gtgcgagacatatactcgttctaccccctgctcatcaagtacgtggatctgcagcgaaac cactggctgaaggacaacataccggaggccgaggagctctacaaccatgtggcagagatc ttcaatatatggtccaagagccagtacttccttaaggaggagcagaacttcatctctgcc aatgagatcgacaacatggccctgatcatgccaactgcaaccaggagatcggccatctcg gaaggtgctcctgccgtgggtggcaaggtaaagaagaagaagaagaacagggacaagaag cgcgacaaggacaaggaagtgcaggccagtctgatggtggcctgcctgaaacgtctcctg cccgtgggactgaatctgttcgctggtcgagagcaggaactggtgcagcactgcaaggat cggtatctgaagaagatgcccgagtacgatgtgatcgagttcgcccgcaaccagctgacc ctgccagataagctggacccctcggatgagatgtcctggcagcattacctgtactcgaag ctgggcaagacggaggaaccggtggacgaacaggcgctggagaaggccaatgttaactcc aacgagaagggcaaggacaagacgcaggagacggtggatcgcatcgtggcgatggccaag gttctgtttggcctgcacatgatcgaccatccacaacagcagagcaagaatgtctacagg agcgttgtgtcgatccaaaggaagcgtgccgtaatcgcatgcttccgtcagacatcgctg cattctctacccagacatcgggcctgcaacatcttcgcgcgatcctactacgagcagtgg ctgcaggaggagaacgtgggccaagaggtgatggtcgaagatctgacgcagacgttcgag gactccgagaaatctaagaaggagggcgaggagacggacagcaagccggatccgctaacc caactggttaccactttctgccgcggcgccatgacggagcgcagcggtgccctccaggag gatctgctctacatgtcctatgcccagatcgcggccaagtccacgggcaaggaggaggag gagggcggcgacgaggaaggcggtgagggtggcgaagagggcgaaggcaccagcatccat gaacaagagatggagaagcagaagctgctcttccatcaggcacgtctctccaatcgtggc gttgccgaaatggtgctgttgcacatttccgcctccaaaggtataccttcggagatggta atgacgacactcaatctcggcatagccattttgcgcggcggaaacatcgacatccaaatg ggcatgctgaaccacttgaaggaaaagaaggacgttggcttctttacctccatcgccgga ctgatgaactcctgcagtgtactggacctggacgcctttgagcgaaacaccaaagcagag ggtcttggtgtaggttccgaaggcgccgcgggcgagaagaacatgcacgacgcggagttc acctgtgcgctgttccggttcatccagctgacctgcgaaggccacaatttggaatggcaa aactatttgaggacccaggccggtaacaccaccaccgtgaacgtggtcatctgcactgtg gattatttgctgcgtctgcaagagtccatcatggacttctactggcactactccagcaaa gagatcatcgatcccgctggaaaggcgaacttcttcaaggccatcgaagtggcaagccaa gtattcaacaccctcactgaagtcatccagggtccttgtaccctcaatcagcaggccttg gcacactcgaggttgtgggatgcagttggtggcttcctcttcctgttctcccacatgcag gacaaactgtccaagcactccagccaagtggatctgcttaaggaactgctaaatctgcaa aaggacatgatcaccatgatgctttccatgctggaaggaaacgttgttaacggcactatt ggcaagcagatggtggacacgctggtggagtcggccagcaatgtggagctgattcttaag tacttcgacatgttcctgaagctcgccgaccttatcgaatcgcccagcttccacgaagtg gacatgaagaacgagggttgggtgacacccaaagactttagggaaaagatggagcaatcc aagaactacacaccggaagaaatggatttccttttggcctgctgcgagcgcaaccacgag ggcaagatcgattaccgggccttcgtggagcacttccacgaaccatcaaaggagatcggt ttcaacctggctgtgctcctgaccaacctcagcgagcacatgccaaacgaaccgcgcctg gcgcgcttcctggagaccgccggctcggtgctcaactacttcgagcccttcctgggccgc atcgagattctcggcagctccaagcgcatcgagcgcgtttactttgagatcaaggactcg aacatcgaacagtgggagaagccccagattcgcgagtccaagcgtgccttcttctattcc atcgtcaccgaaggtggcgacaaggagaaactggaggcctttgtgaacttctgcgaggac gccatctttgagatgactcacgcctcgggactaatggccaccgatgatggcggtggcaat gttaagcgggacactgcctatagttcctacatgagcgaggaagaggaggagcgagctgct cgtgatcccatccgccgcaccatcaccgccgtcaaggaaggactgaagttcggagtgcac atgcttagtccggcgaacatcaagcatcagatcggagtgatgcagaccaaatccatacca gaactcattgtcggctttttcaagatcatcttttatatattttactataccggatatgcg cacttctgcgtggtgcgttacatatttggcatcctactgaacctgatgcgaggacctgct ccagagcaggaggaggaaccggtggtggaggaggaaacgtttggaagagcactgccaccg ttgccgcttgaagaaccaccgggcacagtacaagcctttggcctggacatcaacaaggag gagaacggcatgtacaaggtggtggtgcacgagtctccagccaattcctcgatggaggag ggcggagaatccagtcccgaggacggagcagctgccagcggcgaattggtcgaaggtgaa ccacaccaggagcccatttccattgtggatctgctgggtggagaggctgcaaagaaggcg gcacaggagcggcaggaggcgcaaaaggctcaggaggccgctatggcctccatcgaggcg gaagccaagaagtcgtcatctgcgcctcaggagactccagccgtccaccagatcgacttc tctcagtacacccatcgcgccgttagcttcctcgccagaaacttctacaacctcaagtat gtggccttggtgctggctttcagcattaacttcatgctgctcttctacaaagtcacctca tttaccgaagaagcagacagctcggccgaggaggagctcatcctgggctccgggtcggga ggaggtgcggacatcactggctctggctttggcggatcaggggacgggggatcgggcgat ggcgaaatggaggacgagataccggaacttgtgcacgtggacgaagacttcttctacatg gaacacgttctccgcattgcggcatgtctgcactcacttgtctccctggccatgttgatt gcctactaccacctcaaggttccactggccatcttcaagcgagagaaggagattgcccgc cgactggagttcgagggattgttcattgcagagcagccggaggatgacgacttcaagtcg cactgggacaagctggtgatttcggcgaaaagtttcccagtgaactactgggacaagttc gtgaagaagaaggtgcgccaaaagtacagcgagacctacgactttgactcgatctccaat ctgctgggcatggagaagagcacgttcgcggctcaggagagcgaggaaacgggcatcttc aagtacatcatgaacatcgactggcgctatcaggtgtggaaggctggcgtcaccttcacg gacaacgccttcctctactcgctgtggtacttcagcttctcggtgatgggtaacttcaac aacttcttcttcgccgcccatctgctcgatgtggccgtgggcttcaagaccctgcgcacc atcctgcagtctgtgacccacaacggcaagcaactggtgctgaccgtgatgctgctcacc atcatagtgtacatctacactgtgatcgcgttcaacttcttcaggaagttctacatccag gaggaggacgaggaggtggacaagaagtgccacgacatgttgacctgcttcgtgttccat ctgtacaagggtgtgagagcgggcggtggcataggcgacgagatcggggatccggatgga gacgactacgaggtctaccgcatcatcttcgacatcacgttcttcttcttcgtgatcatt atcctgctggccattatccagggtctgatcatcgacgccttcggcgagctgcgtgaccag ctggagtcggtgaaggacaacatggagtccaactgcttcatctgcgggatgggcaaggac ttcttcgacatagtaccgcacggcttcgacacgcacgtccagaaggagcacaacttggcc aactacatgttcttcctgatgcatttgattaacaagccggacacggagtataccggccag gagacgtacgtgtggaacatgtaccagcagcgcagctgggacttcttcccggtgggagac tgcttccgcaagcagtacgaggatgagctttccggcggaggcggcggcggctaa

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