Dyadobacter sandarakinus: HWI92_14860
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Entry
HWI92_14860 CDS
T07768
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
dsn
Dyadobacter sandarakinus
Pathway
dsn00260
Glycine, serine and threonine metabolism
dsn00261
Monobactam biosynthesis
dsn00270
Cysteine and methionine metabolism
dsn00300
Lysine biosynthesis
dsn01100
Metabolic pathways
dsn01110
Biosynthesis of secondary metabolites
dsn01120
Microbial metabolism in diverse environments
dsn01230
Biosynthesis of amino acids
Module
dsn_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
dsn_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
dsn_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
dsn00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HWI92_14860 (thrA)
00270 Cysteine and methionine metabolism
HWI92_14860 (thrA)
00300 Lysine biosynthesis
HWI92_14860 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HWI92_14860 (thrA)
Enzymes [BR:
dsn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HWI92_14860 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HWI92_14860 (thrA)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
ACT
NAD_binding_3
GDH2_N
Motif
Other DBs
NCBI-ProteinID:
QRR02094
UniProt:
A0ABX7I7M5
LinkDB
All DBs
Position
complement(3679941..3682397)
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AA seq
818 aa
AA seq
DB search
MKVLKFGGTSVGTADSIRTVIGIIENNLTSGEQIAVVFSAMGGVTNRLIEIGKMAAAGNT
EYIEFLKGVEERHFAVVRSLIPVKNQSSTFAAVRGLFNELEDILRGVSWIKELSERTLDL
VMSFGERLSTLVITEILKSRNVHAEFCDARQIIHTNATYGMGDVNFEITNRQILEHFAKT
AALQCVTGFIASTAEGITTTLGRGGSDYTASIIAAALDAEVIEIWTDVDGMMTADPRKVA
NAFTIPSISYAEAMELSHFGAKVIYPPSLQPAFAKNITLKVLNTFNVNFEGTFVQKAANG
KDYAITGISSIDEIVLVNIQGSGMIGVAGISGRLFTALSNNAISVILISQASSEHSICFS
IDPKNAVKAREVLEKEFAVEIGLGHIDHIAIEKSLSIIAIVGEGMKKSTGVSGKLFSVLG
KNGINVVATAQGSSELNISVVIAKSDLSKALNAIHGVFFQSETRSLNLFIVGVGLIGGTL
LEQVRNQAGYLREEKLLNLNIAGLTNTKKMLLAPEGIKPEGWRDRVMDEGVKTSLPAFVQ
RIIELNLPNSVFIDCTSDKDIVQYYHVLLDASISVVTPNKVANSGSYSEYISLQRTALQR
GVKFLYETNVGAGLPIINTIQGLIASGDKFLKIEAILSGTLSYIFNNFGPGVRFADVVRE
AKAKGFTEPDPRDDLSGADVGRKILILAREVGVPLEPEEIRIAKILPENCLAAATVDAFF
AELEISDSYFAGIQAEAEARGEKLRYIATLENGRASIELKTVGPQHPFYTLSGSDNIVSF
TTERYKDRPLVIKGPGAGAEVTASGVFADIMSISSYLG
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgaaggttcttaaatttggtggcacctcagtcggaacggccgacagcatcaggacggtg
atcggtattattgaaaataacctcacgtccggtgagcagatcgccgtggtattttcagcc
atgggcggcgtcacgaaccgcctgatcgaaattggcaaaatggccgctgccggcaatacc
gagtacatcgagttcctgaaaggcgttgaggagcgccactttgccgtagtacgcagcctc
atccctgttaaaaatcagagcagcacatttgcagccgtcagggggcttttcaatgagctg
gaagatattctccgcggtgtttcgtggatcaaagagctttccgaacgtacgctcgacctg
gtcatgagctttggagagcggctgtcgaccctggtgattacggaaatcctgaaaagccgc
aatgtgcatgccgagttctgtgatgcacgccagatcattcataccaatgctacatacggc
atgggcgacgtcaactttgagattaccaaccgccagatccttgaacattttgcaaaaaca
gctgcattgcaatgtgtaaccgggtttatcgcctccacagccgaaggtatcaccaccacg
cttggccgcggcggctcggattatacggcttccatcatcgcagctgcgcttgatgcggag
gtgatcgaaatatggacggatgtggacgggatgatgacggcggatccgcgcaaggtggcc
aatgcattcacgattccctccatttcgtatgcagaagctatggaactgtcgcattttggc
gcaaaggtgatttatccgccaagtctgcagcctgcatttgccaaaaatatcacactcaaa
gtactgaatacctttaatgtaaactttgagggaacatttgtacaaaaagcggcaaatgga
aaagattacgccatcacggggatttcgtccattgatgagatcgtgctggtcaatatccag
ggtagcgggatgatcggtgtggccggtatttcgggccggctgtttacggctttgtccaac
aatgcgatcagtgtcatcctcatttcacaggcatcctcagagcattcgatctgtttttcc
attgatccgaaaaatgctgtaaaagcccgcgaagtgcttgaaaaagagtttgccgtggag
atcgggctcgggcacattgatcatattgccattgaaaaaagcctttccattatcgcgatc
gtgggtgaaggcatgaaaaagagcaccggggtttcgggcaagctgttttctgttttgggt
aaaaacgggatcaacgtggtggctacggcacaaggctcttcggagctgaacatttccgta
gtaatcgcaaaaagtgacctttccaaagcgctcaatgcaattcacggcgtctttttccag
tcggaaacacgctcgctgaacctttttatcgtgggcgtgggactgattggcggtaccctg
cttgaacaggtaagaaaccaggccggatacctgcgggaggaaaagctccttaacctgaat
atcgccggtcttaccaataccaagaaaatgctgctggcaccggaaggtatcaagcccgaa
ggctggcgcgaccgggtcatggatgaaggcgtaaaaaccagtctcccggcatttgtacag
cgcattatcgagctcaacctgcccaacagtgttttcatcgattgtacttcggacaaagac
attgtacagtactaccacgtgctcctcgatgcgagcatttcggtggtgacacccaataaa
gtggccaattcgggctcctactcggagtatatttcattgcagcgcacggctttgcagcgg
ggtgtcaaatttttgtacgagacgaatgtaggggcgggtctgccaatcatcaataccatc
cagggactgattgccagcggcgacaagttccttaaaatcgaggcgatcctttcaggcacg
ctatcctatattttcaacaacttcgggccgggtgtcaggtttgcggacgttgtgcgcgaa
gccaaggccaaaggatttaccgagcccgacccgcgcgatgacctgagcggagccgacgtc
ggccggaaaatactgatccttgcccgggaagtaggcgtccccctggaacccgaagaaatc
aggattgcgaaaattttgcctgaaaactgtctggcagcagctactgtggatgcatttttt
gcagaactggagatttcggacagctattttgccggaatacaggccgaggccgaagccagg
ggtgaaaagctcaggtacattgccacgcttgaaaacggcagggccagtattgagctgaaa
accgtagggccgcagcatcctttttacacactttcaggcagcgataacattgtgtccttt
accacggagcgctacaaagaccgcccgctggtgatcaaaggccccggcgccggcgccgag
gtgacagcatccggcgtgtttgcggatattatgagcattagtagctatttggggtga
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