Dipodomys spectabilis (banner-tailed kangaroo rat): 122096216
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Entry
122096216 CDS
T07891
Symbol
Atp2a1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp04020
Calcium signaling pathway
dsp04022
cGMP-PKG signaling pathway
dsp04024
cAMP signaling pathway
dsp04148
Efferocytosis
dsp04260
Cardiac muscle contraction
dsp04261
Adrenergic signaling in cardiomyocytes
dsp04380
Osteoclast differentiation
dsp04919
Thyroid hormone signaling pathway
dsp04972
Pancreatic secretion
dsp05010
Alzheimer disease
dsp05017
Spinocerebellar ataxia
dsp05022
Pathways of neurodegeneration - multiple diseases
dsp05410
Hypertrophic cardiomyopathy
dsp05412
Arrhythmogenic right ventricular cardiomyopathy
dsp05414
Dilated cardiomyopathy
dsp05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
122096216 (Atp2a1)
04024 cAMP signaling pathway
122096216 (Atp2a1)
04022 cGMP-PKG signaling pathway
122096216 (Atp2a1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122096216 (Atp2a1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
122096216 (Atp2a1)
09153 Circulatory system
04260 Cardiac muscle contraction
122096216 (Atp2a1)
04261 Adrenergic signaling in cardiomyocytes
122096216 (Atp2a1)
09154 Digestive system
04972 Pancreatic secretion
122096216 (Atp2a1)
09158 Development and regeneration
04380 Osteoclast differentiation
122096216 (Atp2a1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122096216 (Atp2a1)
05017 Spinocerebellar ataxia
122096216 (Atp2a1)
05022 Pathways of neurodegeneration - multiple diseases
122096216 (Atp2a1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
122096216 (Atp2a1)
05412 Arrhythmogenic right ventricular cardiomyopathy
122096216 (Atp2a1)
05414 Dilated cardiomyopathy
122096216 (Atp2a1)
05415 Diabetic cardiomyopathy
122096216 (Atp2a1)
Enzymes [BR:
dsp01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
122096216 (Atp2a1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
CA109-like
Motif
Other DBs
NCBI-GeneID:
122096216
NCBI-ProteinID:
XP_042522593
LinkDB
All DBs
Position
Unknown
AA seq
1157 aa
AA seq
DB search
MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDICSLNEFSITGSTYAPEGEVLKNDKPIRAGQYDGLVELATICALC
NDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMILDDSARFMEYENDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSESEEVTDRAYTGREFDD
LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYAEDGPHVSYSQLTHFMQCTEDNPDFGGLDCEIFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALDLNQWLMVLKISLPVIGLDELLKFIARNYLEGKACPCADPAARALSPTLPFAPRACAC
ARPLFQVVSSRPWWDQCPQGGAAQAPPHSAAQGRVAVRAAARSIMASLYPLWPQDNHPSM
SLNRVTGIAPSCPAAAPCRSLPARASLRSLALSTAPPRAVAAALRFHTAAQSCPQRGHQH
LWVLPTRRRHYCCAALR
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagagcacagaggaatgtttggcctattttggggtgagtgag
accacaggcctcaccccggatcaagtgaagcgacatctggagaaatacggccccaatgag
ctccctgccgaggaagggaagtccctgtgggagctggtggtagagcagtttgaagacctc
ctggtgcggatccttctactggctgcttgcatttccttcgtgctggcttggtttgaggaa
ggtgaagagaccattactgcctttgtggaaccctttgtcatcctcttgatcctcattgcc
aatgccatcgtgggggtttggcaggagcgcaatgcagagaatgccattgaagcgctgaag
gaatatgaacccgagatggggaaggtctaccgagctgaccgcaagtccgtgcaaaggatc
aaggctcgggacatcgtccccggggacatcgtggaggtggctgtgggggacaaagtccct
gcagacatccgcattttatccatcaaatctaccaccctccgggttgaccagtccatcctg
acaggtgagtcagtgtctgtcatcaagcacactgaccctgtccccgacccccgagctgtc
aatcaggataagaagaacatgctcttctcgggtaccaacatcgcagccggcaaggccctg
ggcatcgtggccaccactggcgtaagcactgagattggcaagatccgagaccagatggct
gccaccgagcaggacaagacccctctgcagcagaagctcgatgaatttggggagcagctc
tccaaggtcatctccctcatttgtgtggccgtgtggctcatcaacatcggccacttcaac
gatcccgtccacgggggctcgtggttccgaggagccatctactacttcaagattgctgtg
gctctggctgtggcggccattccagaaggtctccccgctgtcatcaccacctgcctggcc
ttgggtacccgtcggatggcgaagaagaacgccatcgtgcggagcctgccgtctgtggag
accctgggctgcacctctgtcatctgttccgacaagacaggcacccttaccaccaaccag
atgtccgtctgcaagatgttcatcattgacaaggtggacggtgatatctgctcactgaat
gagttctccattaccggttccacttatgctcctgagggggaagtcttgaagaatgataag
ccaatccgggcagggcagtatgacgggctggtggagctggccaccatctgtgccctgtgc
aatgactcttccttggacttcaatgagaccaaaggtgtctatgagaaggttggggaggcc
accgagacggcgctcaccacgctggtggagaagatgaacgtgtttaacacggaagtgcga
agtctctcgaaggtggagagagcaaatgcctgcaactcggtgatccgtcagctgatgaag
aaggaattcacactggagttctcccgagacaggaagtccatgtctgtctattgctcccca
gccaagtcttcccgagctgctgtaggcaacaagatgttcgtcaagggtgcccccgagggt
gtcattgaccgctgcaactatgtgcgagttggcaccacccgggtgccgctgacaggcccg
gtgaaggagaagatcatggccgtgatcaaggagtggggcaccggccgggacaccctgcgc
tgcctggccctggccacccgagacacaccccctaagcgggaggagatgatcctggatgac
tcagccaggttcatggaatacgagaatgacctgacattcgtgggtgtggtgggcatgctg
gacccaccccgcaaagaggtcacaggctctattcagctatgccgggatgctgggatcagg
gttatcatgatcaccggagacaacaagggcacagccattgccatctgccgaagaattggc
atcttttcggagagcgaggaggtgacagatcgcgcctacactggccgtgagtttgacgac
ctgcccctggctgagcagcgggaagcctgcagacgcgcctgctgcttcgcccgcgtggag
ccctcccacaagtccaagatcgtggagtatctgcagtcctacgatgagatcacagccatg
acaggagacggtgtcaatgatgcccctgccctgaagaaggctgagattggcattgctatg
ggatctggcactgctgtggccaagacagcctctgagatggtgctggccgacgacaacttc
tccaccatcgtggcggcggtggaggaaggccgggccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaatgtgggcgaggtggtctgtatcttcctcacagcggcc
ttggggctgcccgaggccctgatccctgtgcagctcttgtgggtgaacttggtgacggat
gggctcccagccactgccctgggcttcaacccaccagacctggacatcatggaccggccc
ccccggagtcccaaggagcccctcatcagtggctggctcttcttccgctatatggccatt
gggggctatgtgggtgcagccacggtgggcgcggctgcctggtggttcttgtacgcagaa
gatgggcctcacgtctcctacagccagctgactcactttatgcagtgtacggaggacaac
ccggactttggcggcctggactgcgagatctttgaggcccccgagcccatgaccatggcc
ttgtccgtgctggtcaccattgagatgtgcaacgctctcaacagcctgtctgagaaccag
tctctgatgcggatgccgccctgggtgaacatctggctgctcggctctatctgcctgtcc
atgtccctccacttccttatcctctatgtcgacccgctgccgatgatcttcaagctccgg
gccctggacttgaatcagtggctcatggtcctgaagatctcccttccagtcattgggctg
gatgagctcctcaagttcattgctcggaactacctggagggtaaggcctgcccctgtgct
gaccccgcagcccgggccctgagccccactctgccctttgcgccgcgagcatgcgcgtgc
gcgcgtcctctgtttcaggtggtaagttctcggccctggtgggaccagtgtccccaggga
ggcgcagcccaggcccctccccactccgctgcacaggggcgggtcgctgtccgggccgct
gcccgttcgataatggcctctctctatcctctctggccgcaggataaccacccctccatg
tctttgaaccgtgtcacaggtattgccccttcctgcccggctgctgcgccctgccgctcg
ctcccagcccgcgcgtccctgcggtcgctcgcgctctccacagctccccctagagccgtg
gccgctgccctgcgcttccacacagctgcgcaaagctgccctcagcgtgggcaccagcat
ctctgggtcctgcccacccgcaggcgccattactgctgcgctgcgctgcgctga
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