KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122097416
Entry
122097416         CDS       T07891                                 
Symbol
Akt2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01521  EGFR tyrosine kinase inhibitor resistance
dsp01522  Endocrine resistance
dsp01524  Platinum drug resistance
dsp04010  MAPK signaling pathway
dsp04012  ErbB signaling pathway
dsp04014  Ras signaling pathway
dsp04015  Rap1 signaling pathway
dsp04022  cGMP-PKG signaling pathway
dsp04024  cAMP signaling pathway
dsp04062  Chemokine signaling pathway
dsp04066  HIF-1 signaling pathway
dsp04068  FoxO signaling pathway
dsp04071  Sphingolipid signaling pathway
dsp04072  Phospholipase D signaling pathway
dsp04140  Autophagy - animal
dsp04150  mTOR signaling pathway
dsp04151  PI3K-Akt signaling pathway
dsp04152  AMPK signaling pathway
dsp04210  Apoptosis
dsp04211  Longevity regulating pathway
dsp04213  Longevity regulating pathway - multiple species
dsp04218  Cellular senescence
dsp04261  Adrenergic signaling in cardiomyocytes
dsp04370  VEGF signaling pathway
dsp04371  Apelin signaling pathway
dsp04380  Osteoclast differentiation
dsp04510  Focal adhesion
dsp04550  Signaling pathways regulating pluripotency of stem cells
dsp04611  Platelet activation
dsp04613  Neutrophil extracellular trap formation
dsp04620  Toll-like receptor signaling pathway
dsp04625  C-type lectin receptor signaling pathway
dsp04630  JAK-STAT signaling pathway
dsp04660  T cell receptor signaling pathway
dsp04662  B cell receptor signaling pathway
dsp04664  Fc epsilon RI signaling pathway
dsp04666  Fc gamma R-mediated phagocytosis
dsp04668  TNF signaling pathway
dsp04722  Neurotrophin signaling pathway
dsp04725  Cholinergic synapse
dsp04728  Dopaminergic synapse
dsp04810  Regulation of actin cytoskeleton
dsp04910  Insulin signaling pathway
dsp04914  Progesterone-mediated oocyte maturation
dsp04915  Estrogen signaling pathway
dsp04917  Prolactin signaling pathway
dsp04919  Thyroid hormone signaling pathway
dsp04920  Adipocytokine signaling pathway
dsp04922  Glucagon signaling pathway
dsp04923  Regulation of lipolysis in adipocytes
dsp04926  Relaxin signaling pathway
dsp04929  GnRH secretion
dsp04931  Insulin resistance
dsp04932  Non-alcoholic fatty liver disease
dsp04933  AGE-RAGE signaling pathway in diabetic complications
dsp04935  Growth hormone synthesis, secretion and action
dsp04936  Alcoholic liver disease
dsp04973  Carbohydrate digestion and absorption
dsp05010  Alzheimer disease
dsp05017  Spinocerebellar ataxia
dsp05132  Salmonella infection
dsp05135  Yersinia infection
dsp05142  Chagas disease
dsp05145  Toxoplasmosis
dsp05152  Tuberculosis
dsp05160  Hepatitis C
dsp05161  Hepatitis B
dsp05162  Measles
dsp05163  Human cytomegalovirus infection
dsp05164  Influenza A
dsp05165  Human papillomavirus infection
dsp05166  Human T-cell leukemia virus 1 infection
dsp05167  Kaposi sarcoma-associated herpesvirus infection
dsp05168  Herpes simplex virus 1 infection
dsp05169  Epstein-Barr virus infection
dsp05170  Human immunodeficiency virus 1 infection
dsp05200  Pathways in cancer
dsp05205  Proteoglycans in cancer
dsp05207  Chemical carcinogenesis - receptor activation
dsp05208  Chemical carcinogenesis - reactive oxygen species
dsp05210  Colorectal cancer
dsp05211  Renal cell carcinoma
dsp05212  Pancreatic cancer
dsp05213  Endometrial cancer
dsp05214  Glioma
dsp05215  Prostate cancer
dsp05218  Melanoma
dsp05220  Chronic myeloid leukemia
dsp05221  Acute myeloid leukemia
dsp05222  Small cell lung cancer
dsp05223  Non-small cell lung cancer
dsp05224  Breast cancer
dsp05225  Hepatocellular carcinoma
dsp05226  Gastric cancer
dsp05230  Central carbon metabolism in cancer
dsp05231  Choline metabolism in cancer
dsp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dsp05415  Diabetic cardiomyopathy
dsp05417  Lipid and atherosclerosis
dsp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122097416 (Akt2)
   04012 ErbB signaling pathway
    122097416 (Akt2)
   04014 Ras signaling pathway
    122097416 (Akt2)
   04015 Rap1 signaling pathway
    122097416 (Akt2)
   04370 VEGF signaling pathway
    122097416 (Akt2)
   04371 Apelin signaling pathway
    122097416 (Akt2)
   04630 JAK-STAT signaling pathway
    122097416 (Akt2)
   04668 TNF signaling pathway
    122097416 (Akt2)
   04066 HIF-1 signaling pathway
    122097416 (Akt2)
   04068 FoxO signaling pathway
    122097416 (Akt2)
   04072 Phospholipase D signaling pathway
    122097416 (Akt2)
   04071 Sphingolipid signaling pathway
    122097416 (Akt2)
   04024 cAMP signaling pathway
    122097416 (Akt2)
   04022 cGMP-PKG signaling pathway
    122097416 (Akt2)
   04151 PI3K-Akt signaling pathway
    122097416 (Akt2)
   04152 AMPK signaling pathway
    122097416 (Akt2)
   04150 mTOR signaling pathway
    122097416 (Akt2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122097416 (Akt2)
  09143 Cell growth and death
   04210 Apoptosis
    122097416 (Akt2)
   04218 Cellular senescence
    122097416 (Akt2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122097416 (Akt2)
   04550 Signaling pathways regulating pluripotency of stem cells
    122097416 (Akt2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122097416 (Akt2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122097416 (Akt2)
   04613 Neutrophil extracellular trap formation
    122097416 (Akt2)
   04620 Toll-like receptor signaling pathway
    122097416 (Akt2)
   04625 C-type lectin receptor signaling pathway
    122097416 (Akt2)
   04660 T cell receptor signaling pathway
    122097416 (Akt2)
   04662 B cell receptor signaling pathway
    122097416 (Akt2)
   04664 Fc epsilon RI signaling pathway
    122097416 (Akt2)
   04666 Fc gamma R-mediated phagocytosis
    122097416 (Akt2)
   04062 Chemokine signaling pathway
    122097416 (Akt2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122097416 (Akt2)
   04922 Glucagon signaling pathway
    122097416 (Akt2)
   04923 Regulation of lipolysis in adipocytes
    122097416 (Akt2)
   04920 Adipocytokine signaling pathway
    122097416 (Akt2)
   04929 GnRH secretion
    122097416 (Akt2)
   04915 Estrogen signaling pathway
    122097416 (Akt2)
   04914 Progesterone-mediated oocyte maturation
    122097416 (Akt2)
   04917 Prolactin signaling pathway
    122097416 (Akt2)
   04926 Relaxin signaling pathway
    122097416 (Akt2)
   04935 Growth hormone synthesis, secretion and action
    122097416 (Akt2)
   04919 Thyroid hormone signaling pathway
    122097416 (Akt2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122097416 (Akt2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    122097416 (Akt2)
  09156 Nervous system
   04725 Cholinergic synapse
    122097416 (Akt2)
   04728 Dopaminergic synapse
    122097416 (Akt2)
   04722 Neurotrophin signaling pathway
    122097416 (Akt2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122097416 (Akt2)
  09149 Aging
   04211 Longevity regulating pathway
    122097416 (Akt2)
   04213 Longevity regulating pathway - multiple species
    122097416 (Akt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122097416 (Akt2)
   05205 Proteoglycans in cancer
    122097416 (Akt2)
   05207 Chemical carcinogenesis - receptor activation
    122097416 (Akt2)
   05208 Chemical carcinogenesis - reactive oxygen species
    122097416 (Akt2)
   05230 Central carbon metabolism in cancer
    122097416 (Akt2)
   05231 Choline metabolism in cancer
    122097416 (Akt2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122097416 (Akt2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122097416 (Akt2)
   05212 Pancreatic cancer
    122097416 (Akt2)
   05225 Hepatocellular carcinoma
    122097416 (Akt2)
   05226 Gastric cancer
    122097416 (Akt2)
   05214 Glioma
    122097416 (Akt2)
   05221 Acute myeloid leukemia
    122097416 (Akt2)
   05220 Chronic myeloid leukemia
    122097416 (Akt2)
   05218 Melanoma
    122097416 (Akt2)
   05211 Renal cell carcinoma
    122097416 (Akt2)
   05215 Prostate cancer
    122097416 (Akt2)
   05213 Endometrial cancer
    122097416 (Akt2)
   05224 Breast cancer
    122097416 (Akt2)
   05222 Small cell lung cancer
    122097416 (Akt2)
   05223 Non-small cell lung cancer
    122097416 (Akt2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122097416 (Akt2)
   05170 Human immunodeficiency virus 1 infection
    122097416 (Akt2)
   05161 Hepatitis B
    122097416 (Akt2)
   05160 Hepatitis C
    122097416 (Akt2)
   05164 Influenza A
    122097416 (Akt2)
   05162 Measles
    122097416 (Akt2)
   05168 Herpes simplex virus 1 infection
    122097416 (Akt2)
   05163 Human cytomegalovirus infection
    122097416 (Akt2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122097416 (Akt2)
   05169 Epstein-Barr virus infection
    122097416 (Akt2)
   05165 Human papillomavirus infection
    122097416 (Akt2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122097416 (Akt2)
   05135 Yersinia infection
    122097416 (Akt2)
   05152 Tuberculosis
    122097416 (Akt2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122097416 (Akt2)
   05142 Chagas disease
    122097416 (Akt2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122097416 (Akt2)
   05017 Spinocerebellar ataxia
    122097416 (Akt2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122097416 (Akt2)
   05418 Fluid shear stress and atherosclerosis
    122097416 (Akt2)
   05415 Diabetic cardiomyopathy
    122097416 (Akt2)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    122097416 (Akt2)
   04932 Non-alcoholic fatty liver disease
    122097416 (Akt2)
   04931 Insulin resistance
    122097416 (Akt2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122097416 (Akt2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122097416 (Akt2)
   01524 Platinum drug resistance
    122097416 (Akt2)
   01522 Endocrine resistance
    122097416 (Akt2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dsp01001]
    122097416 (Akt2)
Enzymes [BR:dsp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     122097416 (Akt2)
Protein kinases [BR:dsp01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   122097416 (Akt2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Kinase-like Pkinase_C PH_20 PH_11 ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 122097416
NCBI-ProteinID: XP_042523823
LinkDB
Position
Unknown
AA seq 481 aa
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMQAIQMVANSLKQRGPGEDSM
DYKCGSPSDSSTPEEMDVAVSRARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLTINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgaacgaggtgtctgtcatcaaagaaggctggctgcacaagcgtggtgaatacatcaag
acttggaggcccaggtacttcctgctgaagagcgatggatccttcattgggtataaggag
agacccgaggctcccgaccagacccttcctcccttaaacaacttctccgttgcagaatgc
cagctgatgaagactgagaggccacggcccaacaccttcgtcatccgctgcctgcagtgg
accacggtcattgagaggaccttccatgtggactcccctgatgagagggaggagtggatg
caggccatccagatggtcgccaacagcctcaagcagcggggcccaggtgaggactcgatg
gactacaaatgtggctcccccagcgactcatccacgccagaggagatggatgtggcagtc
agccgagcccgggccaaggtgaccatgaatgacttcgattatctcaagctcctgggcaag
ggcacctttggtaaagtcatcctggtgcgggagaaggccacgggccgctactatgccatg
aagatcttgcggaaggaggtcatcattgccaaggatgaagtcgcccacacagtcacggag
agccgggtcctccagaacactaggcaccccttcctcaccgcactcaagtacgccttccag
acccacgaccgcctgtgcttcgtgatggaatatgccaacggaggggagctgttcttccac
ctgtcccgggagcgtgtgttcacggaggaccgcgcgcgcttctatggcgcagagatcgtc
tcagccctggagtacctgcactctcgggatgtggtataccgagacatcaagctggagaac
ctcatgctggacaaagatggccacatcaagatcactgacttcggcctatgcaaagagggc
atcagtgatggtgccaccatgaaaaccttctgcgggaccccggagtacctggcgcccgag
gtgctggaggacaacgactacggccgggcggtagactggtgggggctgggcgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcatcctcatggaggagatccgcttcccacgcacgctcggccccgaggccaagtccttg
cttgccgggctgctcaagaaggaccccaagcagaggcttggtggggggcccagcgatgcc
aaggaggtcatggagcacaggttcttcctcaccatcaactggcaggatgtggtacaaaag
aagctcctgccacccttcaaacctcaggtcacctccgaggtggacaccaggtacttcgat
gacgagttcaccgcgcagtccatcaccatcacaccgccggaccgctatgacagcctgggc
tcactggagctggaccagcggacgcacttcccccagttctcctactcagccagcatccgt
gagtga

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