KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122098454
Entry
122098454         CDS       T07891                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial-like
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00140  Steroid hormone biosynthesis
dsp01100  Metabolic pathways
dsp04913  Ovarian steroidogenesis
dsp04925  Aldosterone synthesis and secretion
dsp04927  Cortisol synthesis and secretion
dsp04934  Cushing syndrome
Module
dsp_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    122098454
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    122098454
   04925 Aldosterone synthesis and secretion
    122098454
   04927 Cortisol synthesis and secretion
    122098454
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    122098454
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:dsp00199]
    122098454
Enzymes [BR:dsp01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     122098454
Cytochrome P450 [BR:dsp00199]
 Cytochrome P450, animal type
  CYP11 family
   122098454
SSDB
Motif
Pfam: p450 DUF6895
Other DBs
NCBI-GeneID: 122098454
NCBI-ProteinID: XP_042524817
LinkDB
Position
Unknown
AA seq 526 aa
MFPKGFPGRLVLVQSCQPAWGTRRQSPGHPGVPGRGTATLSTPWPRPFHEIPSPGDNGWL
NLFRFWREEGAQGIHHHHVRSFQKYGTIYREKLGNIESVYIMDPEDVAVLFKGEGRHPER
YLIPPWVAYHQCYQKPTGVLLKKSEAWKTDRMVLNQEVMSPEAIKNFVPMMEAVSQDFVR
LLNRRVKQQCSGTFSGDLSHDLFRFAFESITSVIFGERLGMLEEIVDPDNQRFIDAIEHM
FHSSVPMLHLPPGLFRLLRTKIWKDHKEAWDTIFNKASNYTQNFYLDLRRRRKVDRYPGV
LHSLLEQNKLPQENIEANVTEMLAGGVDTTSMTLQWQLYEMGRHPKVQEQLRREVLAARR
QAGGSMAAMLHLVPLLKASIKETLRLHPISVTVQRYPENDLVLQNYKIPAKTLVQVANYA
MGRDPSVFPNPSNFQPARWLEKDKAATHFRFLSFGWGVRQCLGRRIAELEMAVLLMHVLE
NFRIELQQLSEVGTKFSLILVPDKPILLTLLPLAPAPAPPMAQGDP
NT seq 1581 nt   +upstreamnt  +downstreamnt
atgtttcccaaaggctttcctgggcgcttggtcctggtgcaaagctgccagcccgcctgg
ggcacgcgccgccagagccccgggcatcccggcgtgccaggccgaggcacggccaccctg
tccacgccctggccgcgtcccttccacgagatcccgtcccccggggacaatggctggctg
aacctattccgcttctggagggaggaaggcgcccagggcatccaccaccaccacgtgcga
agcttccagaagtatgggaccatctacagggagaagcttgggaacatagagtctgtgtat
atcatggaccccgaggacgtggcggtgttgtttaagggggaagggcgtcacccggagcgc
tacctcatcccgccctgggtggcctatcaccagtgctaccagaaacccaccggcgtgctg
ctcaagaagtcggaggcctggaagacagaccgcatggtcctgaaccaggaggtgatgtct
ccggaggccatcaagaacttcgtgcccatgatggaggccgtgtctcaggactttgtcaga
ctgctgaacagacgcgtgaagcagcagtgctccggaaccttctcaggggacctcagtcac
gacttgttccgctttgccttcgagtcgatcacctccgtcatattcggggagcggctgggc
atgctggaggagatagtcgacccggacaaccagaggttcatcgacgccattgaacacatg
ttccacagcagcgtgcccatgctgcacctgccgcccggcctcttccgcctcctccgcacc
aagatctggaaggatcacaaggaagcctgggacacgattttcaacaaagccagcaactac
actcagaacttctacctggacctgagacggagaaggaaggtggacaggtacccaggcgtg
ctccacagcctcctggagcagaacaagctcccgcaggagaacatcgaggccaatgtcacg
gagatgctggcggggggcgtggacacgacctccatgacgctgcagtggcagctgtacgag
atgggccgccacccgaaggtgcaggagcagctgcggagagaggtgctggccgcgcggcgc
caggccgggggcagcatggccgccatgctccacctggtcccgctcctcaaagccagcatc
aaggagacgctgaggctgcaccccatctctgtaaccgtgcagagatacccggagaacgac
ttagtgctccagaactacaagatccctgccaagacgctggtgcaggtggccaactacgcc
atgggccgggatcccagcgtcttccccaaccccagcaacttccagcccgcgcgctggctg
gagaaagacaaggcggccacgcacttccggttcctcagcttcggctggggcgtgcgccag
tgcctgggccgcaggatcgcagagctggagatggcggtgctgctcatgcacgtgctggag
aacttccgcatcgaactgcagcagctcagcgaggtggggaccaaattcagcctcatcctg
gtgccggacaagcccatcctcctcaccctcctgcccctcgccccggcccccgccccgccg
atggcccagggggacccctga

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