KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122098457
Entry
122098457         CDS       T07891                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial-like
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00140  Steroid hormone biosynthesis
dsp01100  Metabolic pathways
dsp04913  Ovarian steroidogenesis
dsp04925  Aldosterone synthesis and secretion
dsp04927  Cortisol synthesis and secretion
dsp04934  Cushing syndrome
Module
dsp_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    122098457
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    122098457
   04925 Aldosterone synthesis and secretion
    122098457
   04927 Cortisol synthesis and secretion
    122098457
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    122098457
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:dsp00199]
    122098457
Enzymes [BR:dsp01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     122098457
Cytochrome P450 [BR:dsp00199]
 Cytochrome P450, animal type
  CYP11 family
   122098457
SSDB
Motif
Pfam: p450 DUF6895
Other DBs
NCBI-GeneID: 122098457
NCBI-ProteinID: XP_042524820
LinkDB
Position
Unknown
AA seq 526 aa
MFPKGFPGRSVLVQSCQPAWGTRRQSPGHPGVPGRGTATLSTPGPRPFHEIPSPGDNGWL
NLFRFWREEGAQGIHHHHVRSFQKYGTIYREKLGNIESVYIMDPEDVAVLFKGEGRHPER
YLIPPWVAYHQCYQKPTGVLLKKSEAWKTDRMVLNQEVMSPEAIKNFVPMMEAVSQDFVR
LLNRRVKQQCSGTFSGDLSHDLFRFAFESITSVIFGERLGMLEEIVDPDNQRFIDAIEHM
FHSSVPMLHLPPGLFRLLRTKIWKDHKEAWDTIFNKASNYTQNFYLDLRRRRKVDRYPGV
LHSLLEQNKLPQENIEANVTEMLAGGVDTTSMTLQWQLYEMGRHPKVQEQLRREVLAARR
QAGGSMAAMLHLVPLLKASIKETLRLHPISVTVQRYPENDLVLQNYKIPAKTLVQVANYA
MGRDPSVFPNPSNFQPARWLEKDKAATHFRFLSFGWGVRQCLGRRIAELEMAVLLMHVLE
NFRIELQQLSEVGTKFSLILVPDKPILLTLLPLAPAPAPPMAQGDP
NT seq 1581 nt   +upstreamnt  +downstreamnt
atgtttcccaaaggctttcctgggcgctcggtcctggtgcaaagctgccagcccgcctgg
ggcacgcgccgccagagccccgggcatcccggcgtgccaggccgaggcacggccaccctg
tccacgcccgggccgcgtcccttccacgagatcccgtccccgggggacaacggctggctg
aacctattccgcttctggagggaggaaggcgcccagggcatccaccaccaccacgtgcga
agcttccagaagtatgggaccatctacagggagaagcttgggaacatagagtctgtgtat
atcatggaccccgaggacgtggcggtgctgtttaagggggaagggcgtcacccggagcgc
tacctcatcccgccctgggtggcctatcaccagtgctaccagaaacccaccggcgtgctg
ctcaagaagtcggaggcctggaagacagaccgcatggtcctgaaccaggaggtgatgtct
ccggaggccatcaagaacttcgtgcccatgatggaggccgtgtctcaggactttgtcaga
ctgctgaacagacgcgtgaagcagcagtgctccggaaccttctcaggggacctcagtcac
gacttgttccgctttgccttcgagtcgatcacctccgtcatattcggggagcggctgggc
atgctggaggagatagtcgacccggacaaccagaggttcatcgacgccattgaacacatg
ttccacagcagcgtgcccatgctgcacctgccgcccggcctcttccgcctcctccgcacc
aagatctggaaggatcacaaggaagcctgggacacgattttcaacaaagccagcaactac
actcagaacttctacctggacctgagacggagaaggaaggtggacaggtacccaggcgtg
ctccacagcctcctggagcagaacaagctcccgcaggagaacatcgaggccaatgtcacg
gagatgctggcggggggcgtggacacgacctccatgacgctgcagtggcagctgtacgag
atgggccgccacccgaaggtgcaggagcagctgcggagagaggtgctggccgcgcggcgc
caggccgggggcagcatggccgccatgctccacctggtcccgctcctcaaagccagcatc
aaggagacgctgaggctgcaccccatctctgtaaccgtgcagagatacccggagaacgac
ttagtgctccagaactacaagatccctgccaagacgctggtgcaggtggccaactacgcc
atgggccgggatcccagcgtcttccccaaccccagcaacttccagcccgcgcgctggctg
gagaaagacaaggcggccacgcacttccggttcctcagcttcggctggggcgtgcgccag
tgcctgggccgcaggatcgcagagctggagatggcggtgctgctcatgcacgtgctggag
aacttccgcatcgaactgcagcagctcagcgaggtggggaccaaattcagcctcatcctg
gtgccggacaagcccatcctcctcaccctcctgcccctcgccccggcacccgccccgccg
atggcccagggggacccctga

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