Dipodomys spectabilis (banner-tailed kangaroo rat): 122103174
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Entry
122103174 CDS
T07891
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
122103174 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dsp03032
]
122103174 (Top2a)
03036 Chromosome and associated proteins [BR:
dsp03036
]
122103174 (Top2a)
Enzymes [BR:
dsp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
122103174 (Top2a)
DNA replication proteins [BR:
dsp03032
]
Eukaryotic type
DNA Topoisomerases
122103174 (Top2a)
Chromosome and associated proteins [BR:
dsp03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
122103174 (Top2a)
Centrosome formation proteins
Centriole proteins
122103174 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
122103174
NCBI-ProteinID:
XP_042529548
LinkDB
All DBs
Position
Unknown
AA seq
1524 aa
AA seq
DB search
MEVSPLQPLSENMQMNKKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQHL
WVYDEEIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMYVPALIFGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMNNMGKAGEMELKPFSGEDYTCVTFQPDLSKFKMQNLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQV
QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDR
KEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFLGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIEE
LASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH
TDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRD
FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESDNEKSESVPDSGPSFNYLLDMPLWYLTKEKKDELC
KQRNEKEQELDTLKKKSPSDLWKEDLAAFIEELEVVEAKEKQDEQIGFPGKGGKAKGKKT
QMMEVLPSPQGKRVIPQVTIEMKAEAEKKIKRKIKSENTETKEDGMEIEGLKERLEKKQK
REPGAKVKKQTTLPFKPVKKGKKKNPWSDSDSDMSSTESNFDVPPREIEPRRAATKSKFT
VDLDSDEDFSDFDEKIEDEDFVPSDASPPKTKAPPKHTEKELKPQKSATSVVNLDDAEEN
VAPSSSLPSADLPAKIEILAQPSKKNVTVKKTATKSQSSTSVAGTKKRAAPKKTKTDPAL
NSDNSQKPDPAKNKTRRKRKPSTSDDSDSNFEKIISKAATSKKPKGETDEFLLDFDSAVA
PRAKSVRAKKPIKYLEESDEDDLF
NT seq
4575 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccgctgcagcctttaagtgaaaatatgcaaatgaacaaaaagaaaaat
gaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacacaattggaa
cacattttgctccgcccagacacctacattggatctgtggaattagtgacccagcatttg
tgggtttatgatgaagaaattggcattaactatagagaagtcacttttgttcctggtttg
tacaaaatctttgatgagattctagttaatgctgccgataataagcaaagggaccccaaa
atgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaataat
ggaaaaggaattcctgttgttgaacataaagttgaaaagatgtatgttcctgctctcata
tttggacatctcttaacttccagtaactatgacgatgatgaaaagaaagtaacaggtggt
cgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaaaca
gccagtagagagtacaagaaaatgttcaaacagacatggatgaataacatggggaaagct
ggtgagatggagctcaagccctttagtggagaagattatacatgcgtcaccttccagcct
gatttatccaagttcaaaatgcaaaacctagacaaagatattgttgcactaatggttaga
agagcatatgatattgccggatcaactaaagatgtcaaagtctttcttaatggaaataag
cttccagtgaaaggattccgtagctatgtggatatgtatctgaaggataagttagatgaa
actggcaacccattgaaagtaatacatgaacaagtaaaccacagatgggaagtgtgctta
acaatgagtgaaaaaggatttcagcaaattagctttgtcaatagcattgctacttccaag
ggtggcagacatgttgactatgtagctgatcagattgtgagtaaacttgttgatgtcgtg
aagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatgtgg
atttttgtgaatgccttaattgaaaacccaacttttgactctcagacaaaagaaaacatg
actttacaagccaagagctttgggtcaacatgtcaattaagtgaaaaattcatcaaagcg
gcaactggctgtggtattgtagaaagcatactaaattgggtgaagtttaaggcccaagtc
cagttaaacaagaagtgttcagctgtaaaacataatagaatcaaaggaattcccaaactt
gatgatgccaatgatgcagggagccgaaactctacggagtgtacacttatcctgactgaa
ggagactcagccaaaactttggctgtatcaggccttggtgtagttgggagagacaaatat
ggggttttccctctcagaggaaaaatactcaatgtccgagaagcttctcataaacagatc
atggaaaatgcagaaattaacaatatcatcaagattgttggtcttcagtataaaaaaaac
tatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgacagat
caggaccaagatggttcccatatcaaaggtttgctaattaattttattcatcacaactgg
ccctcccttctgcgacatcgttttctggaggaatttatcactcccattgtgaaggtgtct
aaaaacaagcaagaaatggcattctacagccttcctgaatttgaagaatggaaaagttct
actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca
aaagaagctaaggaatactttgcagatatgaaaagacatcgaatccaattcaaatattct
ggacctgaagatgatgctgcaatcagcctggcttttagcaagaaacagatagatgatcga
aaggaatggctaactaattttatggaggatagaagacaacggaagttacttggccttcct
gaggattatttatatggacaaactaccacttatctgacgtacaatgacttcataaacaag
gaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtagatggt
ttgaaaccaggtcagagaaaagttttgtttacttgtttcaaacggaatgacaaacgagag
gtaaaggttgcccagttagctgggtcagtggcagagatgtcctcttatcatcatggtgag
atgtcattaatgatgaccattatcaatttggctcagaattttttgggtagcaataatttg
aacctattgcagcccattggtcagttcggtaccaggctgcatggtggcaaagactctgct
agccctcgatacatctttacaatgctcagccctttggctcggttgttatttccaccaaaa
gatgaccacacactaaagttcttatatgatgacaatcaacgtgttgaacctgaatggtac
atacctattatacctatggtgctaataaatggtgctgaaggcatcggaactgggtggtcc
tgcaaaattcccaactttgatgttcgtgaagttgtaaataacatccggcgtttgatggat
ggagaagaacctttgccaatgctgccaagttacaagaacttcaagggtactattgaagag
ctggcttcaaatcaatatgtaattagtggtgaagtagctattcttaattccaccaccatt
gaaatctcagagcttcctatcagaacatggacccaaacatacaaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctctcatcacagactatagggaatatcat
acagatactacagtgaagtttgttgtaaagatgactgaagaaaaactggcagaagcagag
agagttggattacacaaagtctttaaactccaaactagtctcacctgcaattctatggta
ctttttgaccatgtagggtgtttaaagaaatatgacacggtgttggatattctaagagac
ttctttgaactcaggctcaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgccgaatctgctaaactgaacaatcaggctcgctttatcttagaaaaaatagatgga
aaaattgttattgaaaacaagcctaagaaagaacttattaaagttctgatccagagggga
tatgattcagatcctgtgaaagcctggaaagaagcccaacaaaaggttccagatgaggaa
gaaaatgaagaaagtgacaatgaaaagagtgaatctgtaccagattcagggccatccttc
aactaccttcttgatatgcccctttggtatctaaccaaggaaaaaaaggatgaactatgt
aaacaaagaaatgaaaaggagcaagaactggatacattaaagaaaaagagtccatcagat
ttatggaaagaagacttagctgcatttattgaagaattagaggttgttgaagccaaggaa
aaacaagatgaacaaatagggtttcctggaaaaggagggaaagccaaggggaagaaaaca
caaatgatggaagttttgccttctccacaaggaaaaagagtcattccccaagtgaccata
gaaatgaaagcagaagcagaaaagaaaattaaaaggaaaattaagagtgaaaacactgag
actaaggaggatgggatggaaatagaaggcctaaaagaaagattggagaagaaacagaaa
agagaaccaggtgccaaggtaaagaaacaaactacattgccatttaaacctgtcaaaaaa
ggaaagaagaaaaacccctggtcagattcagactcagatatgagtagtactgaaagtaat
tttgatgttcctccacgagaaatagagccacggagagctgcaacaaaatccaaattcaca
gtggatttggattcagatgaagatttttcagattttgatgaaaaaattgaagatgaagat
tttgtcccatcggatgctagtccacctaagaccaaagctcccccaaaacatactgaaaaa
gaactgaagccacagaaaagtgccacgtcagtagttaacttggatgatgctgaagaaaat
gtagccccttcttcaagccttccatctgctgacttaccagctaaaattgaaattctagct
caaccttctaaaaagaatgtgacagtgaagaagacagcaacaaaaagtcagtcttccacc
tctgttgctggtaccaaaaaaagggcagctcccaaaaaaaccaaaacagatccagcctta
aattctgataactctcaaaagcctgatcctgccaagaacaagactcgccgcaaaaggaag
ccatccacttctgatgattctgactctaattttgagaaaatcatttctaaagcagccaca
agcaagaaacccaaaggggagaccgatgagttccttctggactttgactcagctgtggct
cctcgggcaaagtctgtacgagccaagaaacctatcaagtacctcgaagagtcagatgaa
gatgacctgttttaa
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integrated database retrieval system
