Dipodomys spectabilis (banner-tailed kangaroo rat): 122106250
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Entry
122106250 CDS
T07891
Symbol
Lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp05012
Parkinson disease
dsp05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
122106250 (Lrrk2)
05022 Pathways of neurodegeneration - multiple diseases
122106250 (Lrrk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dsp01001
]
122106250 (Lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dsp04131
]
122106250 (Lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dsp04147
]
122106250 (Lrrk2)
Enzymes [BR:
dsp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122106250 (Lrrk2)
Protein kinases [BR:
dsp01001
]
Serine/threonine kinases: TKL group
LRRK family
122106250 (Lrrk2)
Membrane trafficking [BR:
dsp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
122106250 (Lrrk2)
Exosome [BR:
dsp04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
122106250 (Lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_14
LRR_9
WD40_2
WD40_CDC20-Fz
WDR55
Beta-prop_EML
Arf
LRR_NXF1-5
Beta-prop_RSE1_2nd
Beta-prop_EML_2
Ank_2
T2SSE
nSTAND3
AAA_22
LRR_13
MMR_HSR1
ABC_tran
TrwB_AAD_bind
Arm
AAA_16
AAA_7
Kdo
PduV-EutP
WD40_MABP1-WDR62_2nd
G-alpha
cobW
Septin
Beta-prop_RIG_2nd
MobB
Pox_A32
GTP_EFTU
TsaE
NACHT
LRR_6
Beta-prop_WDR19_1st
AAA_29
TniB
FtsK_SpoIIIE
ResIII
AAA_23
ARM_CUL7_CUL9
Motif
Other DBs
NCBI-GeneID:
122106250
NCBI-ProteinID:
XP_042533478
LinkDB
All DBs
Position
Unknown
AA seq
2530 aa
AA seq
DB search
MASGSCQGCEEEDEETLKKLLVRLNNVQEGKQIETLVQILEDMLVFTYCDHASKLFEGKN
FHVPLLIVLDSYMRVASVQQVGWSLLCKLIEVCPDTLQSLMGPQDVGNDWEVLGIHQLIL
KMLTVHHANVNLSTVGLKALELLLTSGKITLLILDEESDIFLLIFDAMNTFSANEEVQKL
GCKALHVLFERVSEEQLIEFVENKDYRILLSALQNFKGEEEIVLHVLHCLHSLAVPCSNV
EVLMSGNVRCYNIVIDAMRAFPIHEKIQQVSCCLLHRLTLGNFFNILVLNEVHEFVVKAV
ERYPKNAVLQISALSCLALLTETIFLNQDLEEKNETPESEKEEEVEEQEKLFWLEACYRA
LTWHRKNKHVQEAACWALNNLLMYQNGLHKKIGDEDGQFPAHREVMLAMLMHSCAKEVFQ
ASATALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNMS
LDTMAVVVPKIITIMKNHQTSLSVQLEALRAIVHFIVPGMPDVSRDEFQRKLNMVKKQSF
RNDIYKLVLSALNRFIGNPGIQRCGLKVISSLAHFPDVLEMLSLDGAVDSVLHTLQMYPD
DQEVQCLGLQLLGCLSTKKNICIGTGHLLAKILVSSLQRFKDVLEVQIIGFQTILAILDL
SEPFSKLLLHHSFESVIFHQMSLGITEPKGPQFLNLCCKCFAKLVMDPELKSVMLQRACD
QNNSIMVECLLLLGADANQAKEATSLICQVCEKESSPKLVELLLNSGSREQDVRKALMIS
MQKGDSHIISLLLRRLALDLANNSICLGGFGIGKIEPSWLAPLFPDKISNLRKQTNMGSM
LARMVLRYQMRSTVEEGAAAGSDENFSEDVLDKLGEWTFIPDSSMDSVFGQSDDLDSEGS
ESSFLVKKKSNSISVGEFYRDPALQRCSPNLQRHSNSLGPVFDHEDMLKRKIKILSSDDS
VRSSKLPSHMRHSDSISSLASEREYITALDLSANELRDIDALSQKCCISGHLEHLEKLEL
HQNALTNFPQQLCETLKCLTHLDLHSNKFTSFPSYLLKMNCLAHLDASRNDIGLPVVLDP
ALKCPTLKQFNLSYNQLSSVPENLAEAVEKLEQLILEGNKISEICSPLSLKELKVLNLSK
NNISSLPENFLKACPKVESFSARMNFLAAMPFLPSSITSLKLSQNKFTCVPDVILNLPHL
RSLDMSSNDIESLPGPSHWKSLNLRELLFSYNRISILDLSEKAHTWSRVEKLHLSHNKLK
EIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHVGCKAKDI
IRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGIQGATVGIDVKDWPI
QIRGKKRKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNI
KARASSSPVILVGTHLDVSDEKQRKACIGKITKELLNKRGFPAIRDYHCVNATEESDALA
KLRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVK
ENQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVDPKWLCKVMAQILTVKVEGY
PKHPKGIISRKDVEKFLSKKKRFPKNYMIQYFKLLEKFQIALPLGEEYLLVPSSLSDHRP
VIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGI
YLNWSPEAYCLVRSEILDNHPESFLKIIVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEI
DICGEGETLLKKWALYSFNDGEDHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPD
LILADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLR
QELVVLCHLHHPSLISLLAAGIRPRMLVMELASRGSLDRLLQQDKASLTRTLQHRIALHV
ADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGF
RAPEVARGNVIYNQQADVYSFGLLLYDILTAGGRIVEGLKFPNEFDELALQGKLPDPVKE
YGCTPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMKHISIPENIIAECMVAT
NSNSKNVSIWLGCGHSDKGQLSFLDLNTEEHITEQEVTDSRILCLAFVHLPAEKESWIVS
GTQSGVLLVIDAEDRTKRHSLEKMTDSITCLYCNCFSKQSKQKNFLLVGTANGNLAIFED
KAVKCNGAAPLKTLSLGDASTPLMCLSESMISSEKHIMWGGCGTKVFSFSNDFSVQKLIE
TRTNQLFSYAAFSDSNIIAVAVDTALYVAKKNSPVVEVWDKKTEKLCELIDCVQFLKEVM
VKISKESKHNLCYAGRVKALCLQKNTALWIGTGGGHILLLDLSTRRIIRIINNFCDSVRV
MVTAQLGSLKNVMLVLGYKQKSTEGTQQQKEIQSCLSIWDINLPHEVQNLEKHIEVRKEL
AEKMRKTSIE
NT seq
7593 nt
NT seq
+upstream
nt +downstream
nt
atggctagtggcagctgtcagggatgcgaagaggaggacgaggaaactctgaagaagttg
ctagtcagactgaacaatgtccaggaaggaaaacagatagagacgctagttcaaatcctg
gaggacatgctggtgttcacctactgcgatcacgcctccaagttattcgaaggcaaaaat
ttccacgtgcctctgctgatcgttttggattcctatatgagagtcgccagtgtgcagcag
gtgggctggtcacttctgtgtaaattaatagaagtctgtccagatacattgcaaagctta
atgggaccccaagatgttggaaatgattgggaagtccttggtattcaccaactgattctt
aaaatgctaacagttcatcatgctaatgtaaacctgtcaacagttggactgaaggcctta
gagctcctgctaacttcaggcaagatcacattgctgattctggatgaagaaagtgatatt
ttcttgttaatctttgatgccatgaacacattttcagccaacgaagaggtccagaaactt
gggtgcaaggcgttacatgtgctgtttgaaagagtgtctgaggaacaattgattgaattt
gttgagaacaaagattataggatattgttaagtgcattacaaaacttcaaaggtgaagag
gaaattgtgctccatgtactgcattgtttgcattctctagcggttccttgcagtaacgtt
gaagtcctcatgagtggcaatgtcaggtgttacaacattgtgatagatgctatgcgagca
ttccccatccatgaaaagattcagcaggtcagttgctgcttgctccatcggctgacctta
ggtaattttttcaatattctggtattaaatgaggtccatgagtttgtggtgaaggctgtg
gagagatatccaaagaatgcagtgttacaaatctcagctctcagctgcttagcactcttg
actgagaccattttcttaaatcaagacttagaggaaaagaatgagactccggagagtgag
aaggaggaggaggtggaagaacaagaaaaactgttctggttagaagcctgctatagagct
ttaacatggcacagaaagaataaacatgtgcaggaggctgcatgttgggcattaaacaat
cttctcatgtaccaaaatggtttacacaagaagattggagatgaagatggccagtttcca
gctcacagggaagtgatgcttgctatgctgatgcattcttgcgccaaggaagtcttccag
gcgtctgcaactgcattgtcaactctcttggaacaaaatgttaattttagaaaaatcctg
ctgtcaaaaggaatatacctgaatgttttggagttaatgcagaaacacatacattctccg
gaagtggctgaaagtggatgtaagatgctcaatcatctttttgaaggaagtaacatgtcc
ctggataccatggcagtagtggtccccaagataataacaattatgaaaaaccatcagaca
tcattgtccgtgcagctggaggctcttcgggctattgtgcacttcatagtgcctggcatg
ccagatgtttctagagatgaatttcagcgtaaactaaatatggttaagaaacagtctttc
aggaatgatatttataagctggtcttatcggctttgaacaggttcattggcaatcctggg
attcagagatgcggattgaaagtaatttcttcgctagcacatttccctgatgtgctggag
atgctgtccctggatggtgcagtggactcagtgcttcacacactgcagatgtatccagat
gaccaagaagttcagtgtctgggtttacaactcttaggatgcttgagtaccaagaagaat
atatgcataggaactggacacctgctggctaagattttagtgtccagtttacaacgattt
aaagatgttcttgaagtgcagatcataggatttcagacaatcttggccattctggacttg
tcggaacccttttctaagctgctcttgcaccattcatttgagtccgtaatattccatcag
atgtctttaggcatcacggaaccaaagggcccacagtttctcaatctctgttgcaaatgt
tttgcaaaactggtgatggaccccgagttaaaaagtgtgatgttacaaagagcctgtgat
cagaataatagcatcatggtagaatgcttgcttctcctgggagcggatgccaatcaagcc
aaggaggcaacttctttaatttgtcaggtctgtgagaaggagagcagccctaaattggtg
gagctgctgctgaatagcgggtcccgtgaacaggatgtacggaaagcgctgatgatcagc
atgcagaagggtgacagccatatcatcagcttgctcttaagaaggctggccctggacctg
gccaacaacagcatctgcctgggagggtttggtataggaaaaattgaaccttcttggctg
gctcctttatttccagataagatatccaatttaaggaaacaaacaaacatgggttctatg
ctagcgaggatggtactcaggtaccagatgagaagcaccgtggaggaaggagcagctgca
gggagtgatgaaaatttctctgaagatgtactggataagcttggtgaatggactttcatt
ccagattcttccatggacagtgtgtttggtcaaagtgatgatctggatagtgaaggaagt
gaaagttcatttcttgtgaagaagaaatccaattccattagtgtgggagaattttaccgt
gatcctgcgttgcaacgttgctccccaaatttgcaaaggcattccaattcattggggcct
gtttttgatcatgaagatatgctgaagcgaaaaataaaaatattgtcttcagatgattca
gtcaggtcatcaaaacttccatctcacatgaggcattcagacagcatttcttccctggct
tctgagagagagtatattacggcattagacctttcagccaatgaactcagagatattgat
gccctgagccagaaatgctgtataagtggtcatttggagcatcttgaaaagttggagctt
caccagaatgcactcaccaacttcccacagcaactatgtgaaaccctaaagtgtttgaca
cacttggatttgcacagtaataagttcacatcctttccctcctacttgttgaaaatgaat
tgccttgcccacctggatgcctctcgaaatgacattggactcccagtggtgttagatccg
gccttgaagtgccccaccctgaagcagttcaacttgtcatataaccagctctcttctgta
cccgagaacctcgctgaagctgtggagaaactggagcagctcatcttagaagggaataaa
atatcagaaatatgttcccctttgagcctgaaggaattgaaggttttaaaccttagtaag
aacaacatctcatccctgccagagaactttcttaaagcttgtccaaaagtagagagtttc
agtgccaggatgaattttcttgctgctatgcctttcttgccttcttccataacaagccta
aaactatctcaaaataaatttacatgtgttccagatgtaattttaaatctaccacactta
cggtccttggatatgagcagcaatgacattgaaagtctgcctggaccttcacactggaaa
tctttgaacttaagggaactcttgtttagctacaatcggatcagcatcttggacttgagc
gaaaaagcacacacatggtctagagtagagaaactacacctttcccataataaactgaag
gagattcctcctgagattggctgtcttgaaaatctgacatctctggatgtcagttacaac
ttggaactgagatcatttcccaatgagatggggaaattaagcaaaatatgggatcttcct
ctggatgaattgcgtctaaattttgattttaaacatgtcggatgcaaagccaaagacatc
atcagatttcttcaacagcggttaaaaaaggctgtgccttacaaccgaatgaaactcatg
attgtaggaaatactgggagtggcaaaactaccttactgcagcaattaatgaaaaccaag
aaatcggatcttgggattcagggtgccacggttggcattgatgtgaaagactggcccatc
caaatcaggggcaagaagaggaaggacctcattctaaacgtgtgggattttgcaggtcgt
gaagaattctacagcactcacccccacttcatgacccagcgagcactataccttgctgtc
tatgatctcagcaaggggcaggcggaagtggatgccatgaaaccctggctcttcaatata
aaggctcgtgcgtcctcctccccggtcattcttgtgggcacacatctggacgtttctgat
gagaagcagcgcaaggcctgcatagggaaaatcaccaaggagctgttgaacaagcgaggc
tttcccgcaatccgagattaccactgtgtgaacgccacggaggaatctgatgctctagct
aaacttcggaaaactatcataaacgagagtctgaatttcaagattcgagaccagcctgtt
gtggggcagctaattccagactgctacgtggaacttgagaaaatcattttatcagagcgc
aaaaatgtgccaattgaatttcctgtgattgataggaaacgattactacaactagtgaaa
gaaaaccagctacagttagatgaaaatgagctccctcatgcggtacatttcttaaatgaa
tcaggagtccttcttcattttcaagacccagcactgcagttaagtgacttatattttgtg
gaccccaagtggctttgtaaagttatggcccagattttgacagtaaaagtggaaggctat
ccaaaacatcccaagggaattatctcacggaaagatgtggaaaaatttctttcaaagaag
aaaagatttccaaagaactacatgatacagtactttaaactcttagaaaagttccagatt
gccttgccactaggagaagagtatttactggttccaagcagtttatctgaccacagacct
gtgatagagcttcctcattgtgagaactctgaaattatcattcgactctatgaaatgccc
tattttcccatgggattctggtcaagattaatcaatcgattgcttgaaatttcaccttac
atgctttctggaagagaacgagcacttcgcccaaacagaatgtactggcggcaaggcatc
tacttgaattggtctcctgaggcttattgtctggtgagatctgaaatcttagacaatcat
ccagagagtttcttaaaaatcatagttccttcttgtagaaaaggctgcattcttttgggc
caagttgtggaccacattgattctctcatggaagaatggtttcctgggttgctggagatt
gatatttgtggtgaaggtgaaactctgttgaagaaatgggcattatacagttttaacgat
ggcgaagatcatcagaaaatcttacttgacgacttgatgaagaaagcagaagaaggagac
cttctagtaaacccagatcaaccgaggctcaccattccgatctctcagattgcccctgac
ctgattttggccgacctgcctagaaatattatgttgaataatgatgagttggaatttgag
caagctccagaatttctcttaggtgatggcagttttggatctgtttatcgagcagcctat
gaaggtgaggaagtggctgtgaagatttttaataaacatacatcacttaggctgttacga
caagagctggtggtgctttgccaccttcatcaccccagcttaatatctttgctggcggct
gggattcgtcctcgaatgttggtgatggagttggcctccaggggctccttagatcgcctg
cttcagcaggacaaagccagcctcacccgaactctccagcacaggatcgcccttcatgtg
gctgatggcttgagatacctgcactcggccatgattatataccgagacttgaagccccat
aatgtgctgctttttaccctgtatcccaatgcggccatcattgcaaagattgctgactat
gggatcgctcagtactgctgcagaatgggaataaagacatcagagggaacaccaggattt
cgagcacctgaagttgctagaggaaatgtcatttataaccagcaggctgatgtttactcc
tttggcctgttactctatgacattttgacagctggaggtagaatagtagaaggtttgaag
tttccaaatgagtttgatgaattagccctgcaaggaaaattacctgatccagtcaaagaa
tatgggtgcaccccatggcctatggttgagaagctaattaaaaaatgtttgaaagaaaac
cctcaggaaaggcctacttctgcccaggtctttgacattctgaattcagctgagttaatc
tgtctgatgaagcacatttccataccagaaaacattatagctgaatgcatggttgctaca
aattctaatagcaagaatgtgagcatttggttaggctgtgggcacagtgacaaaggccag
ctctcctttcttgacttaaacacagaagaacacattactgagcaggaagttactgacagt
agaatattgtgcttggcctttgtgcatctccctgctgaaaaggagagctggatcgtgtca
gggacgcagtctggtgttctcctggtcattgatgctgaagatcggaccaaaagacattca
ctggaaaagatgactgattccattacttgtttgtattgtaattgcttttccaagcagagc
aagcagaaaaattttcttttggtgggaactgctaatggtaacttagcaatttttgaagat
aaagctgttaagtgtaatggagcggctcccttgaagactttgagcctgggagatgcgagc
actccactcatgtgcttgagtgaatcgatgatctcctctgagaaacacatcatgtgggga
ggatgtggcacgaaggtgttctcattctctaatgacttctccgttcagaaactcattgag
accaggacaaaccagctgttttcctatgcagctttcagtgattcaaacatcatagcagtt
gccgtagacacagccctctatgttgcaaagaaaaacagcccagttgtggaagtgtgggac
aagaagacagaaaagctctgtgaactaatagactgtgtgcagtttttaaaagaagtcatg
gtaaaaataagcaaggaatcaaagcacaatctgtgttatgctgggagggtgaaggccctc
tgccttcagaagaacacggcgctctggataggaactggaggaggccatattttactcctg
gacctttccacgcggcgaattatacggataattaacaacttctgtgattccgttcgagtc
atggtgacagcacagttaggaagccttaaaaatgtcatgctggttttggggtacaaacag
aaaagtactgaaggtactcaacaacaaaaagagatacagtcttgcttatctatttgggat
atcaatcttccacacgaagtgcaaaatttggaaaaacacattgaagtgaggaaagaatta
gctgaaaaaatgagaaaaacgtccattgaatag
DBGET
integrated database retrieval system
