Dipodomys spectabilis (banner-tailed kangaroo rat): 122108095
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Entry
122108095 CDS
T07891
Symbol
Top2b
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
122108095 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dsp03032
]
122108095 (Top2b)
03036 Chromosome and associated proteins [BR:
dsp03036
]
122108095 (Top2b)
Enzymes [BR:
dsp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
122108095 (Top2b)
DNA replication proteins [BR:
dsp03032
]
Eukaryotic type
DNA Topoisomerases
122108095 (Top2b)
Chromosome and associated proteins [BR:
dsp03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
122108095 (Top2b)
Centrosome formation proteins
Centriole proteins
122108095 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
122108095
NCBI-ProteinID:
XP_042536005
LinkDB
All DBs
Position
Unknown
AA seq
1623 aa
AA seq
DB search
MAKSGSGGAGAGAGGNGALTWVTLFDQNNAAKKEESEIANKNDSSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQ
PDLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEV
VKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPA
VDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
EGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGP
DFNYILNMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEA
QEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK
KGDSDTTAVKVEFDEEFSGTPVEGIGEEALTPAAPINKGPKPKREKKEPGTRVRKTPTTT
GKPGAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD
ADDDDDNNDLEELKVKASPIMNDGEDDFVPSDGLDKDEYTFSPGKSKATPEKPSHDKKGQ
DFGNLFSFTSYSQKSEDDSAKFDSNEEDTASVFSPSFGLKQADKVPSKTVAAKKGKPSSD
IAPKPKRAPKQKKVVETINSDSDSEFGIPKKTTAPKGKGRGAKKRKASGSENEGDYNPGR
KTSKPASKKPKKTAFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFA
MFN
NT seq
4872 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggcagcggcggcgcgggagccggcgcgggcggcaacggggcgctgacc
tgggtgactctttttgatcagaacaatgctgcaaagaaagaagagtcagaaatagcaaac
aaaaatgattcttcaaagaagttatctgttgaacgagtatatcagaagaaaacacaactt
gaacacattctccttcgtcctgatacatatattggatcagtggaaccactgacacagtta
atgtgggtatatgatgaagatgtaggaatgaattgcagagaggttacctttgttccaggt
ttatacaagatctttgatgaaatcctcgttaatgctgctgacaataagcagagggataag
aacatgacctgtattaaggtttctattgatcctgaatcaaacattattagcatttggaac
aatgggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcttta
atttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagttacaggt
ggccgcaatggttatggtgcaaaactttgtaatattttcagtacaaaatttacagtagaa
actgcttgtaaagaatacaagcatagttttaagcagacatggatgaacaatatgatgaag
acttctgaagccaaaattaaacattttgatggtgaggattacacatgtataacattccaa
ccagacctgtctaaatttaagatggaaaaacttgacaaggatattgtagccctcatgacc
agaagagcatatgatttggcaggttcatgtaaaggggtcaaggtcatgtttaatggaaag
aaattgcctgtaaatggatttcgcagttatgtagacctttatgtgaaagacaaattggat
gaaactggagtggccttgaaagttattcatgaacttgccaatgaaagatgggatgtttgt
ctcacattgagtgaaaaaggattccagcaaatcagttttgtaaatagtatcgcaactaca
aaaggtggccggcatgtggattatgtggtagatcaagttgttggtaaactgattgaagta
gttaagaaaaagaacaaagctggtgtttcagtgaaaccatttcaagtaaaaaaccacata
tgggtttttattaattgtcttattgaaaatccaacttttgattcccagactaaggaaaat
atgactctgcagcccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaa
gcagcctctaattgtggcattgtagaaagtatcttgaattgggtaaaatttaaggctcag
actcagctgaataagaagtgttcatcagtgaaatacagtaaaatcaaaggcattcccaaa
ctggatgatgctaatgatgctggtggcaaacattccttggagtgtacattgatattgaca
gagggagactctgctaaatcactggcggtgtctggattaggtgtgattggacgagacaga
tatggagtctttccactcaggggtaaaattcttaatgtacgagaagcttctcacaaacag
atcatggaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaagaaa
agctatgatgacgcagaatctctgaaaaccttgcgttatggaaagattatgattatgact
gaccaggatcaagatggctctcacataaaaggcttgcttattaatttcattcatcacaat
tggccatcacttttgaagcatggttttcttgaagaattcattactcctattgtaaaggcg
agcaaaaataagcaagaactttccttctatagtattcctgaatttgatgagtggaagaaa
catatagaaaatcagaaagcctggaaaataaaatactacaaaggattgggtaccagtaca
gctaaagaagcaaaggaatattttgctgatatggaaaggcatcgcattttgtttagatat
gctggtcctgaagatgatgcagccattaccctggcattcagtaagaagaagattgatgac
agaaaagaatggctaacaaattttatggaagaccggagacagcgtaggttacatggtttg
ccagagcaatttttatatggtacagcaacaaagcatttgacttacaatgattttatcaat
aaagaattaattcttttctcaaactctgacaatgaaagatcaataccatctcttgttgat
ggctttaaaccaggccaaagaaaagtcttgtttacttgtttcaagaggaatgataaacgt
gaagtgaaagttgcccagttggcggggtctgttgctgaaatgtctgcgtatcatcatgga
gaacaagcattgatgatgactatagtgaatttggctcagaactttgtgggaagtaacaac
attaacttgcttcagccgattggtcagtttggaactcggcttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagacttctttttcctgct
gtggatgacaacttgcttaagttcctttatgatgataatcaacgagtagagcctgagtgg
tatattcccattatccccatggttttaataaatggtgctgagggcattggtactggatgg
gcttgtaaactgcccaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta
gaaggattggatcctcatcccatgcttccaaactacaaaaattttaaaggcacaatccag
gaacttggtcaaaaccagtatgcagttagtggtgaaattttcgtggtggatagaaacaca
gtagaaattacagagcttccagttagaacctggacacaggtatacaaggaacaggtttta
gaacctatgctgaatggaacagataaaacaccagcattaatttctgattataaagaatat
catactgatacaactgtgaaatttgtggtgaaaatgacagaagagaaactagcgcaagca
gaagctgctggattacataaagtttttaaacttcaaactactcttacttgcaattctatg
gtactctttgatcatatgggatgtctgaagaaatatgaaactgtgcaagatattctgaaa
gaattctttgatttacgattaagttattatggtttacgaaaggaatggcttgtgggaatg
ttgggagcagaatctacaaagcttaacaatcaagctcgtttcattttagagaagatacaa
gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaacacaaaaccagcatgatgatagttcctctgactcaggaactccttcaggccct
gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagag
ctcattaaacagagagatacaaaaggacgagaggtcaatgatcttaaaagaaaatctcct
tcagatctttggaaagaagatttagcagcatttgttgaagaattggataaagtggaagca
caagaacgagaagatattctggcaggaatgtctggaaaagcaataaaaggtaaagttggc
aaacctaaggtgaagaaacttcagttggaagagacgatgccttcaccttatgggagaaga
ataattcctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaag
aagggtgattctgacaccacagcagtgaaagtggaatttgatgaagaatttagtggaaca
ccagtagaaggtataggagaagaggcattgaccccagcggctcctataaataaaggtccc
aaacccaaaagggagaaaaaggagcctggtaccagggttagaaaaacaccaacaacaact
ggtaaacctggtgcaaaaaaagtgaagaaacggaatccttggtcagatgatgagtccaag
tcagaaagtgacttagaagaaacagaacctgtggtgattccaagagattctctgctgaga
agagcagctgctgaaagacctaagtacacatttgatttctcagaagaagaggatgatgat
gctgatgatgatgatgacaataatgatttagaggaactgaaagtaaaagcctctcccata
atgaatgatggggaagacgattttgttccgtcagatggcttagataaagatgaatataca
ttttctccaggcaaatcaaaagctactccagaaaagccttcacatgacaaaaaagggcaa
gattttgggaatctcttctcattcacgtcatactctcagaagtcagaagacgattcagct
aaatttgacagtaatgaagaagatactgcttctgttttttcaccatcatttggtttgaag
caagcagacaaagtaccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagat
atagcccctaagcccaagagagcacctaaacagaagaaagtagtagagaccataaactct
gactcagactcagaatttggcattccaaagaagactacagcaccaaaaggtaaaggccga
ggtgcaaagaaaaggaaagcatcgggctctgaaaatgaaggtgattataaccctggcaga
aaaacatctaaaccagcaagcaagaaaccgaagaaaacagcttttgatcaggattcagat
gtagacatcttcccctcagactttacttctgaacctccttctctgccacggaccggtcgg
gcgaggaaagaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgca
atgtttaattaa
DBGET
integrated database retrieval system
