Dipodomys spectabilis (banner-tailed kangaroo rat): 122108920
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Entry
122108920 CDS
T07891
Symbol
Setx
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122108920 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
dsp03021
]
122108920 (Setx)
Enzymes [BR:
dsp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
122108920 (Setx)
5.6.2.5 RNA 5'-3' helicase
122108920 (Setx)
Transcription machinery [BR:
dsp03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
122108920 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
SEN1_N
UvrD-helicase
AAA_19
AAA_30
AAA_22
ResIII
SLFN-g3_helicase
TniB
AAA_16
Helicase_RecD
nSTAND3
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
122108920
NCBI-ProteinID:
XP_042536898
LinkDB
All DBs
Position
Unknown
AA seq
2668 aa
AA seq
DB search
MSTCCWCTPGGISTLDFLKSYASRTLSGEFHTADEDLCYCLECVAEYHKAREELPFLHEV
LWELETLRLITHFEKSMKAELADDDDDELYIVDSNGEAQLFDFTGQDFENKLRVPLLEIL
KYPYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNL
GKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYW
LGICMLLTILEEQAMDSLLLGSDKQNDFMRSILHTMQKQSNDDSMDPFWPALHCFMVILD
RLGSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTKVEPEPYSDDMVTCSQIVYN
YNPEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSL
MDLKDLGVAYIVEVIHHLYSEVKNVLNHADAGCDKVTEFFLLILVSVIELHRNKKCLHLL
WVSSQKWVEAVVKCAKLPTTAFARISEKSPGSFSKGTTMMSSLSLHSVPSNSVQLACVQL
IRSLLKEGYQLGHHALCKRFWNKLNLFLRGNLSLGWQLTDQETRELQTCLKQIIKNIKGK
ASPCSTPVDLTSASKSPLVSFKEENEEIEKPKKDTNGMENCSPTFTKEPIKMETYQVQES
PLSRAGNIEWEDVKHTYPKDLNEEDQLPSESHLVQNSKGLFTKGAREQVKPSRGKQKSAR
EKVVCTSTSGPERDSDRGVIVSTYLLTDSSTDSLEKVSTSNEDSALTDDHGKTSRPKNKV
HKDEICAKLFRVIKQQPRRSTSLSHAAGAEGSKSDRDAEVESSAIGDSVTCDPSADPEAM
LDVEQGEQKPEDNLLLTKKQWKSEELDLYSPHEKSFQIQERRGKGVVSSTDMTNMTKTLS
PFQHPSAVLESRDTEASKSADWVSSTRDEPSDTTHKPTVGTDCLVDRDLHKVVAQASVIK
FPSNSTRNSSPQLERKVKNDKRCSTTNQNRVADTSYGQVIVISDSDDDEELLELEKHTNQ
DTVSSTKEVPGQCDSDANASGDKKFIKEEDAKSILLESDSQFFEFESASEVFSVWQDHKE
EGSKDSVEEVGGSSGGAHVSAEAEKDSTKRAEPHSRDEELCEMEVKKPRRKQYEKPVAKD
PLRPSSSRKKEQSHDDSDLHAVASETATPSLAALKRSSPKLRTYSKPIRKVPASKTPKKT
HSESKRGQNKSSHYLSCRTTPAVVPPKKFRQCPEPASTVEKLGLKKAPRKAFELSQRSLD
YLVQLRDHGKSVGVVETRKKAKLVSPQTLPVKNNKKLLPDQDDVQLQRQAKPKNRKDVLV
SESTRAKRTRSPVAASVDVVRPESGRPDESGKGTEVLANSGEKQLLHLSSSKAETPPAKR
ASKEPSDDCLLNYCDSRAQNGRMPDSDMPASTAESPGGGDLTGRSGQVAVVNQSELDSGS
DMDDDNLYLTQNDPEDMDLCSQMDTDYAHLIEVIPGEDALPTEDAVHPPHVESSSDTKCK
YKDCVETIKAQSEYCAQHSEAKTADDNVFRKPGLPLSAVRPLRPTTTKVFSSSGSSRIAN
LSRSLDNTTIPSTLRNKPTQSILKMPQSSAVLQKPVAEVKSLRSALNPQSPSSALRSAYR
PPPAASSPANALSSSQSISDTFIKEVLKWKYEMFLNFGQCGAPSSLCQCISRSVPVRFQD
CTEYFDVFLPLMILNTFETMAQEWINSPNKDNCYQVQLKKLAADYKKSWEFVVYLDESEL
AKQLHPKENDLVFLRCGRLSGEKKDTERGSVADHHMYYCGYVHKFRRTALMRSRKSECSL
SIQIQDHLPASLNELMKCVVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPMDFCTKDL
PAMSSERIVSADWMVPGRVRTCVVRRGVSHLKLLHAPLCVREDTSMCSDVWCQPSSFGEG
KINYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENPR
KGHSDENSNAKNKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRL
GPEKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHRKKEFLDHQLDELSRQRALCRGGRE
MQRKELDEKITRVSKERQELASKIKEVQGRPQKTQNNIILESHVICCTLSTSGGLLLESA
FRGQGGQAFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQECGYD
QSMMARFYKLLEESVEQNQIGRLPVVQLTVQYRMHPDICLFPSNYIYNKSLKTNRLTEAN
RCSSDWPFQPYLVFDVADGSERRDNDSYVNIQEIKLVMEIMKLIKDKRRDTTFRNIGIIT
HYKAQKTMIQKDLDKEFDRKGSAEVDTVDAFQGRQKDCIIVTCVRASATQGSIGFLASLQ
RLNVTITRAKYSLFILGHLRTLMENEHWNQLIQDAQKRGAIVKTYDKNYKHDAAKIMKLK
PVLQRGLSHPPTTAPEVARPQGGLPSSKLDGALATTSFAASLYHTPSNSKEAPVTITSNG
PERSCLQERLRDPRLFRRLELDAKGVFPRDPQPSSPQHSGATPPLGEPGFPMSHQDQGGR
GSTTKAAPVSSARSLPQARPPAPSHAGPTSGRRCRNPEPGLSYRRETRAFSRGEQERYSS
VSYYPKRNSYWPRRGPEEDSGAKKRRLL
NT seq
8007 nt
NT seq
+upstream
nt +downstream
nt
atgagcacttgttgctggtgcacaccgggtggcatttccacccttgacttcctaaagagc
tatgcctccaggaccctctctggagaattccacacagctgacgaagacctctgctactgc
ttagaatgtgtggctgaataccacaaagcaagagaagaattgcctttcttgcatgaggtt
ttatgggaattagaaaccctacgtctcataactcactttgaaaaatctatgaaagcagaa
cttgcagatgatgatgatgacgagttatatatagtagacagcaatggagaggcacagctg
tttgactttactggccaagactttgagaataagcttcgcgttcctctgcttgagatactg
aaatacccttacctgcttctacacgagcgtgtcaatgaattatgtgtggaagcactttgt
cggatggagcaagccaactgttcttttcaggttttcgacaaacatccagggatctatctg
tttttggttcatcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttg
gggaaggtagacagagatgattactacgacttacaggaagttttaacttgtctttttaaa
gtcattgagttggggcttctagaaagtccagacatttatacctcttctgtcctggaaaag
ggtaaactgattcttctgccctcacacatgtacgatactaccaactacaaaaactactgg
ctaggtatttgcatgttgctgaccattctcgaggagcaggccatggactcactgttgctg
ggctcagacaaacaaaatgactttatgaggtcgatccttcacaccatgcagaaacaatca
aatgatgatagcatggatcctttctggccagccttacactgtttcatggtgattctggat
cggcttggatctaaggtctggggtcaacttatcgatcctattgaagcatttcaaaccatc
atcaacaatgtgagctataacagagagatccaaaatatacggaacagctctgtgaggaca
aaggtagagccggaaccgtactcggatgatatggttacttgcagccagattgtgtacaat
tacaatcctgaaaagaccaagaaggattcaggatggagatcagccatttgcccagattat
tgtcctaatatgtatgaagaaatggaaacattagccaacgtgctccagtcagatatcggt
caagacatgcgtgtccataacagcacgtttctgtggttcataccttttgtccagtctctc
atggacctgaaggacctgggtgtggcctacatagtagaagttattcaccacctgtactct
gaagtcaagaatgtcctcaaccacgcagatgcaggatgtgacaaagtcacagagttcttt
ctcctgattttggtgtctgtgattgaactgcacagaaataagaaatgtttgcatttgctg
tgggttagttcccagaaatgggtggaagctgttgtgaaatgtgccaagcttcccactaca
gccttcgcacggatttctgagaaatcacctggaagtttctccaaaggaacaacgatgatg
tcctccctgtcgttgcattcggtgccatctaactctgtgcagcttgcttgtgtgcagctc
attaggagtcttctcaaagaaggctaccagcttggccatcacgctctttgcaagcgattc
tggaataagcttaacttattccttcgaggaaatttgtctctaggttggcagttgacggat
caggaaacccgtgagttacagacttgcttaaaacaaattattaagaacataaaaggcaaa
gcctctccatgtagcactccagtggacctgacttctgcttctaaaagcccgcttgtgtct
tttaaagaagaaaatgaagaaatagagaaacccaaaaaagacacgaatggtatggaaaat
tgtagtccaacatttactaaagaaccgatcaaaatggagacctatcaagtgcaagagagt
ccattgagcagagcgggtaacatagaatgggaggatgtgaagcacacttaccccaaggat
ctgaatgaggaagatcaactcccatccgagtcacacttagtgcagaatagtaaaggcctt
tttaccaaaggagctcgagagcaagtgaaacccagtagagggaaacagaagtctgccagg
gagaaagttgtatgcacctcaacaagtggcccagaaagggattctgacagaggagtaatt
gtttcaacatacttgttgactgattctagcactgattctctagaaaaagtgtccacatca
aatgaggattctgctttaacggatgatcatggtaaaacctcgagaccaaagaataaggtg
cataaagatgaaatatgtgcaaagctgttccgtgtcataaagcagcagcctagaaggagt
acttcactcagtcatgctgctggggcagaaggaagcaagagtgaccgtgatgccgaggta
gagagctctgcgataggagacagcgtcacgtgtgatccatctgcagaccctgaagccatg
ctggatgttgagcaaggagaacaaaagcctgaagacaatttattgctgacaaagaaacaa
tggaagagtgaagagttagatttgtactcgcctcatgaaaagagttttcagatacaggaa
agacgtggaaaaggggtggtatcgagtacagacatgaccaacatgacaaagactctgtct
ccctttcaacatccttcagctgtacttgagtcaagagatacggaagcaagtaagagtgca
gattgggtctcctctactagggacgagccctctgacactactcacaagcccactgttgga
acagattgcctggtggaccgagacctccacaaagtagtggcccaagccagtgttattaaa
tttccatcaaattcaaccagaaatagttcaccccaactagaaagaaaagtaaaaaatgac
aaaagatgttccacaactaaccagaacagagttgcagataccagctatgggcaagtgatc
gtcatttcagattctgatgacgacgaggaacttctggaacttgagaaacacaccaaccag
gacacagtaagcagcactaaggaagtgccaggccagtgtgactcggatgcaaatgctagt
ggtgacaagaagtttataaaggaggaagatgcaaagtccattctacttgagtccgattca
cagttttttgagtttgaaagtgcctctgaggtgttttcggtgtggcaggatcataaagaa
gaaggcagcaaggattcagttgaggaggtgggaggaagctcaggtggggcacatgtgtct
gctgaggctgagaaggacagcacaaaacgggcagagccacatagtagagatgaggaactg
tgtgaaatggaagtcaaaaaacctaggagaaaacagtatgaaaaacctgtggccaaagac
cctctaaggccttcatcttctagaaagaaggagcagtctcatgatgacagtgacttgcac
gctgtggcctcagagaccgccacgcccagtctggctgcactgaagaggtcctcgccgaag
ctccggacttactccaagcctatcaggaaggtcccagcctccaaaacgcctaagaagaca
cattctgaatctaaaagagggcagaacaagagttcccattacctgagttgcagaacaact
cctgccgttgtgccacccaagaagttccgccagtgtcccgagccagcttcaaccgttgag
aaactgggtctgaagaaagcccctcggaaggcgttcgagctgtcccagcgctccttagac
tacttggtgcagttacgggatcatggcaaaagtgttggggttgtggagacccgaaaaaag
gccaagttagtttctccgcagactcttcctgtcaaaaacaacaagaaactgctgcccgac
caggatgatgttcagctacaaaggcaggcaaagcctaagaatagaaaagacgttttggtg
agtgaaagtacccgggctaagagaacaaggtcccccgtggctgcgagtgtagatgttgtg
aggccggagtctggcagaccagatgagtccgggaaaggcacagaggtgcttgccaacagc
ggtgaaaaacagctcctccacctctcatcctccaaagcagaaacaccgccagcaaagcgc
gcttcaaaggagcccagtgatgattgtcttctgaactactgtgattctagagcacagaat
ggaaggatgccagacagtgacatgcctgcctcgactgcagagagccctggaggcggtgat
ttgaccggacggagcgggcaggtggcagttgtgaaccagtctgagctggattccggcagc
gacatggatgacgacaatttatatttgacacaaaatgaccctgaagacatggacttatgt
tcacagatggacactgactacgctcacctgattgaagtgattcccggagaagatgcgctt
ccgacagaagatgctgtgcatccacctcacgtggagtcttcgagtgacactaagtgcaag
tacaaagactgtgttgaaaccataaaagcccagagtgagtactgcgcacagcactcagaa
gctaaaacagcagacgacaatgtcttccgcaaacctggcctgcctctttctgcagtcagg
cctttgagacctaccaccactaaggttttcagctcaagtggtagctcacggattgccaac
ctctccaggtctctggacaacactacaatcccatcaactctaagaaataagccaacacag
tcaattctgaaaatgccccagtcctccgcagtattgcagaagccggtggctgaagtgaag
agcttgcgcagtgctctcaacccacagagccccagcagcgccctcaggtcagcctacaga
cctccgccagcagcctcctcgcctgcaaacgcgctctcttcgtcacagtctatctctgac
accttcattaaagaggtcttaaagtggaaatacgagatgtttttgaactttggtcagtgc
ggggcaccgtcgagtctttgtcaatgcatctcaagatctgtgcctgtcagatttcaagat
tgtacagagtattttgatgtttttctccccttgatgatattgaatacttttgaaacaatg
gcacaggaatggatcaactctcccaataaagataattgctatcaggtacagctaaaaaag
cttgcagctgattataaaaaaagctgggagtttgtggtttatctggatgaaagtgaattg
gctaaacagcttcatcccaaggaaaatgatttggtgtttttgcgttgtgggagactaagt
ggagagaagaaagacacggagagaggcagcgtggcagaccaccatatgtattactgtggc
tatgtccataagttccgtcgcactgcgctcatgcgcagtaggaaatcggagtgttccctt
tccatccagattcaagatcacttgccagccagtttaaacgaacttatgaaatgtgttgta
atcagttccctggtaacaacacagaggaaattgaaagccatgtctctgttgagtggtcgg
aaccaactggccagagccattctgaatccaaatcccatggacttctgtaccaaagatcta
ccagctatgtcctctgagagaattgtgagtgctgattggatggtgccagggagagtcaga
acatgtgttgtcaggaggggagtgtcccatttgaagctgctccatgctcctctatgtgta
cgagaagacacgtccatgtgcagtgatgtttggtgtcagccctcctccttcggggagggg
aagattaactacctaaaagatttcaatgaagatcaaaagaaagcaatagaaactgcatat
gccatggtgaaacactcaccatcagttgccaaaatctgtctgattcatgggccacctgga
acaggaaaatcaaaaactattgttggtctgctgtaccgcttactcacagagaacccgagg
aaggggcattctgatgaaaactccaatgcgaaaaacaaacaaaaccgtgtccttgtgtgt
gcaccttcgaatgcagccgttgatgaacttatgaaaaaaatcatcctcgaattcaaagaa
aaatgcaaagataagaaaaatcctttgggaaactgtggagatataaatttagtacgactg
ggtccagaaaagtccattaataatgaggtcctaaggttcagcttggacagccaagttaac
cacagaatgaagaaagacttaccttctcatgttcaagagatgcatagaaagaaggagttt
ctcgatcatcagctggatgagctttcccgccagcgggcgttatgccgaggtggacgggag
atgcagaggaaagagttagatgaaaaaattactagagtttcaaaagaaaggcaagaactt
gcttcaaaaattaaagaggttcagggacgcccccagaaaacacagaacaacatcatcttg
gagtcgcatgtcatctgctgcacgctgagcaccagcgggggtttgctgcttgagtcagct
ttccgcgggcaaggggggcaagccttcagctgtgtcattgtagacgaggctgggcagtcc
tgtgaggtcgagactcttactcccctcatccaccgctgcaacaagctcatcctagtggga
gaccccaagcagctcccacccactgtcatttccatgaaggcacaggagtgtggctatgac
cagtcgatgatggctcgcttctacaagctgctggaggagagtgtggagcagaaccagatc
ggcagactgccagttgtacagctcactgttcagtaccggatgcacccagacatatgtctc
ttcccttccaattacatttataacaaaagcttgaaaacaaataggctcactgaagccaat
cgatgctcctcagactggccatttcagccctacctcgtgtttgatgtcgcagatggttcg
gaaagacgggacaatgactcctacgtaaatattcaagaaataaaattggtgatggaaata
atgaagttgattaaagacaaaagaagagacactacctttcggaacattggcataataacc
cattacaaggctcagaagacgatgattcagaaggacttagacaaagaatttgataggaaa
ggctcggcggaagtggacactgtggacgctttccagggccgtcagaaggactgcatcatc
gtcacctgtgtccgggccagtgccacacaaggctccattggattcctggcaagtttgcag
agattgaatgtcaccatcacccgagccaagtatagtcttttcatcctggggcacctgagg
accctgatggaaaatgagcactggaatcaactgattcaggatgcccagaagcgaggggcc
atagtcaagacctacgacaagaactacaagcacgatgcagcgaagattatgaagctcaag
cctgtgctgcagaggggcctgagccacccccccaccacggccccagaggtggccaggccc
cagggcggcctgcccagcagcaagctggacggcgcactcgccaccacctcttttgctgct
tctctctatcacacgccctccaactccaaggaagcacctgtcaccatcacctcaaatggc
cccgaaaggtcttgtcttcaggagcgcctgagggacccacgactctttagaaggttggag
cttgatgccaagggggtgttccccagggatccacagccgtctagcccccagcattctggg
gcaacccctcccttgggagagccaggctttcccatgagtcaccaggaccagggtggcagg
gggtccactaccaaagcggctcctgtgagcagtgccaggtctctcccgcaggccaggcct
ccggctcccagccatgccgggcctaccagcggaaggaggtgcaggaacccggagccgggg
ctgagctacaggcgggagaccagggcttttagcaggggcgagcaggagaggtacagctcg
gtgtcctactatccaaagaggaactcttactggcccagaagggggcccgaggaggacagt
ggtgccaagaagagacggcttttatag
DBGET
integrated database retrieval system
