Dipodomys spectabilis (banner-tailed kangaroo rat): 122109059
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Entry
122109059 CDS
T07891
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00790
Folate biosynthesis
dsp01100
Metabolic pathways
dsp01240
Biosynthesis of cofactors
dsp01523
Antifolate resistance
dsp04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
122109059 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
122109059 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122109059 (Fpgs)
Enzymes [BR:
dsp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
122109059 (Fpgs)
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
122109059
NCBI-ProteinID:
XP_042537175
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Position
Unknown
AA seq
587 aa
AA seq
DB search
MSWAPGRLRAALLLAAVRGPSAIIRCAARRGLSARLAPQEPGMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQAQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTEHILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFSKHFWHLYHRLEETKDGSSVSMPAYFRF
LTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTMEKIA
WQKGGIFKRGIPAFTVLQPEGPLAVLKDRAQQISCPLYLCPPLETLEEGGAPLALGLEGE
HQRSNAALALQLANCWLQRHHQQTIQELKVSRPGNLWQLPLAPVFQPTSHMRHGLRDTEW
PGRTQVLRRGPLTWYLDGAHTSSSVQACVRWFRQALQRQERLSDGPEVCVLLFNSTGDRD
SAALLKLLQPCRFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCFQHQQHWSCLDKE
QNSPDIWSPSNPGLGGPASLLLASHPPRPCNTSSLVFSCISHALQWISQGRDPVFQPPSP
SRNLLTHPMASSGANVLREAAAIHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgccgggccgcctgcgcgcggctctgctcctggcagcggtccgtgggcct
agtgccatcatccggtgcgcggcgcggcgagggttgagcgcacggctcgcgccacaggaa
cccggcatggagtaccaggatgctgtgcgcatgctcaacaccctacagaccaatgctggc
tacctggagcaggtgaagcgccaaagaggtgatccccaggcacagctggaagccatggag
ctgtacctggcacggagtgggctgcaggtggaggacttggaccggctgaatatcatccat
gtcactgggactaagggaaagggctctacctgtgccttcactgagcatatcctgcgtaac
tatggcctgaaaacaggattctttagctctccccacctggtgcaggtacgagagcggatc
cgcatcaacgggcagcccatcagccctgagctcttcagcaagcacttctggcacctctat
caccgtctggaggaaaccaaggatggcagcagtgtctccatgcctgcctacttccgcttc
cttaccctcatggccttccacatcttcctgcaagagaaggtggacctggcggtggtagaa
gtaggcatcggtggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgtgga
gtgtcttctcttggtattgaccacacgagtcttctgggggacacgatggagaagatagcg
tggcagaaagggggcatctttaagcgtggcatccctgccttcactgtgctccagccggaa
ggtcccctggcagtgctgaaggatcgagcccagcagatctcatgtcctctctacctgtgt
ccaccactggaaaccctggaggaagggggcgctccactggccctaggcctggagggagag
caccagcgttcaaatgcagctttggccttgcagctggccaattgctggctgcaacggcac
catcagcagaccatccaggagctgaaggtatccagaccaggcaacctgtggcagctgccc
ctagcacctgtattccaacctacttcccatatgcgtcatgggcttcgagacacagagtgg
ccaggccggacacaggtgctgcggcgtggacccctcacttggtacctggatggtgcacac
accagcagtagtgtgcaggcctgtgtgcgctggttcagacaggccctgcagaggcaggag
aggctcagtgatgggcctgaggtgtgtgtcttgcttttcaattccactggggacagggac
tctgcagctctcctgaagctgctgcagccctgccggtttgactatgctgttttctgccct
aacctgacagaggtgtcatccacaggcaacgcagaccagcagaacttcactgtgacactg
gaccaggtgctgctccgctgcttccaacatcagcagcactggagttgtctggacaaggaa
caaaacagcccagacatctggagtccttcgaacccagggcttggcgggcctgcttctctg
ctactggcatctcacccaccccgcccctgcaataccagctcccttgtcttcagctgcata
tcacatgccttacagtggatcagccaaggccgggaccctgtctttcagccccccagcccc
tcacggaacctccttactcaccccatggccagcagcggggccaacgttctccgtgaagct
gctgccatccatgtgctggtcactggcagcctgcacttggtgggtggtgtcctaaagctt
ctggacccttccctgtcccagtag
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